摘要
目的:本文探讨无创正压通气(NIPPV)慢性阻塞性肺疾病(COPD)肺动脉高压(AP)及脑钠肽(BNP)的影响。方法选择我院2008年1月~2013年1月所收治的30例COPD合并AP的患者作为研究对象,采用无创正压呼吸机面罩来对患者进行辅助通气治疗7d,对所有患者在接受无创正压通气前以及通气后PaCO2(mmHg)、PaO2(mmHg)、 AP(mmHg)、BNP(pg/ml)变化进行观察、比较。结果本研究所有患者中,有17例患者在经过7d的治疗后,其体内的PaCO2、PaO2、AP、BNP水平与治疗前存在明显差异,具有统计学意义,P<0.05。5例患者在治疗的过程中转为有创通气治疗。结论 NIPPV对无创正压通气对慢性阻塞性肺疾病肺动脉高压及脑钠肽都有明显改善。
Objective To study the noninvasive positive pressure ventilation(NIPPV)in patients with chronic obstructive pulmonary disease(COPD)in pulmonary arterial hypertension(AP)and brain natriuretic peptide(BNP)effect.Methods 30 cases of COPD complicated with AP in our hospital from 2008 January to 2013 January were treated patients as the research object,using non-invasive positive pressure ventilator mask to patients on ventilation for 7 days,al of the patients receiving noninvasive positive pressure ventilation ventilation before and after PaCO2(mmHg),PaO2(mmHg),AP(mmHg),BNP(pg/ml)were observed,compared.Results All patients in this study,17 patients in after 7 days of treatment,in which PaCO2,PaO2,AP,BNP levels before and after treatment has obvious dif erence,with statistical significance,<0.05.5 patients in the course of treatment for invasive ventilation in the treatment of transit.Conclusion NIPPV on noninvasive positive pressure ventilation in both on chronic obstructive pulmonary disease pulmonary hypertension and brain natriuretic peptide significantly improved.
作者
彭慧群
林伟革
刘龙英
PENG Hui-qun;LIN Wei-ge;LIU Long-ying(Department of Internal Medicine,Nanhai District Luocun Hospital,Foshan 528226,Guangdong,China)
关键词
无创正压通气
慢性阻塞性肺疾病
肺动脉高压
脑钠肽
影响
Noninvasive positive pressure ventilation
Chronic obstructive pulmonary disease
Pulmonary artery hypertension
Brain natriuretic peptide
Influence
