摘要
目的观察同仁牛黄清心丸治疗原发性高血压(痰热上扰证)的临床疗效及安全性。方法选取2021年3月—2022年8月于北京同仁堂中医医院就诊的80例原发性高血压(痰热上扰证)患者,随机分为对照组与试验组,各40例,对照组予替米沙坦,试验组加服同仁牛黄清心丸,疗程28 d。比较2组治疗前后血压、眩晕中医证候评分、生活质量评分及安全性。结果治疗后2组SBP、DBP均下降,组内比较P<0.05,组间比较P>0.05。2组治疗后中医证候评分均降低,组内比较P<0.05;试验组组间比较P<0.05,对照组组间比较P>0.05。杜氏高血压生活质量量表评分比较,治疗后2组生活质量均改善,组内比较P<0.05,且试验组改善更显著,组间比较P<0.05。2组均未见不良反应。结论同仁牛黄清心丸联合西药可降低原发性高血压(痰热上扰证)的血压,优势在于改善患者眩晕中医证候,提高生活质量,未见不良反应。
Objective To observe the clinical efficacy and safety of Tongren Niuhuang Qingxin pills in the treatment of essential hypertension(phlegm-heat invading upward syndrome).Methods A total of 80 patients with essential hypertension(phlegm-heat invading upward syndrome)who were treated in Beijing Tongrentang Hospital of Traditional Chinese Medicine from March 2021 to August 2022 were randomly divided into control group and experimental group,with 40 patients in each group.The control group was given telmisartan,and the experimental group was given Tongren Niuhuang Qingxin pill for 28 days.Blood pressure,TCM syndrome score of vertigo,quality of life score and safety of 2 groups before and after treatment were compared.Results After treatment,SBP and DBP decreased in both groups(P<0.05 for intra-group comparison and P>0.05 for inter-group comparison).The TCM syndrome scores of 2 groups were decreased after treatment,and the comparison among groups was P<0.05.The comparison between the experimental group and the control group was P<0.05.Compared with the scores of Duchenne Hypertension Quality of Life scale,the quality of life in both groups improved after treatment(P<0.05),and the improvement in experimental group was more significant(P<0.05).No adverse reactions were observed in both groups.Conclusion Tongren Niuhuang Qingxin pills combined with Western medicine can reduce the blood pressure of essential hypertension(phlegm-heat invading upward syndrome).The advantage is that it can improve the patients’dizziness and TCM syndrome and improve their quality of life without any adverse reactions.
作者
孔繁飞
岳春梅
龙晓华
续晓彤
关伟
杨阳
KONG Fanfei;YUE Chunmei;LONG Xiaohua;XU Xiaotong;GUAN Wei;YANG Yang(Departmentof Internal Medicine,Beijing Tongrentang Hospital of Traditional Chinese Medicine,Beijing 100051,China;Comprehensive Ward,Beijing Tongrentang Hospital of Traditional Chinese Medicine,Beijing 100051,China;Department of Science and Education,Beijing Tongrentang Hospital of Traditional Chinese Medicine,Beijing 100051,China;Science Data Research Laboratory of Traditional Chinese Medicine,Institute of Traditional Chinese Medicine Information,China Academy of Traditional Chinese Medicine,Beijing 100700,China)
出处
《光明中医》
2024年第10期2054-2057,共4页
GUANGMING JOURNAL OF CHINESE MEDICINE
基金
北京市中医药科技发展资金项目(No.JJ-2020-28)
关键词
眩晕
高血压病
痰热上扰证
同仁牛黄清心丸
中医药疗法
vertigo
hypertension
phlegm-heat invading upward syndrome
Tongren Niuhuang Qingxin pill
therapy of TCM
