摘要
目的探讨不同类型结直肠息肉分布的临床特征。方法收集444例结直肠息肉患者的临床资料,分析结直肠息肉与不同性别、年龄、检出部位、病理及直径大小之间的相关性。结果结直肠息肉患者中男性构成比明显高于女性(男∶女=2.02∶1)。检出部位在左半结肠患者比例明显高于右半结肠(64.6%比25.7%)。不同病理类型中,腺瘤性息肉的检出率为(86.1%)高于非腺瘤性息肉(13.9%),且管状腺瘤的低级别上皮内瘤变检出率(83.2%)高于低级别上皮内瘤病变其他病理类型(P<0.001)。女性右半结肠息肉的检出率高于男性,而全肠道息肉检出率低于男性(P<0.05)。年龄≥80岁患者全肠道息肉检出率(37.5%)明显高于其他年龄段(P<0.05)。炎性、增生性息肉的上皮内瘤变检出率(5.9%)明显低于其他类型息肉,且癌变程度随绒毛含量增加而增加(P<0.05)。上皮内瘤变检出率随着息肉直径增大而增加(P<0.05)。结论结直肠息肉直径及绒毛含量与癌变风险呈正相关,为今后临床个体化筛查方案的制定与评判提供了新的思路。
Objective To investigate the clinical characteristics of different types of colorectal polyps.Methods A total of 444 consecutive patients with colorectal polyps were enrolled in the study.The correlation between colorectal polyps and different gender,ages,the detection site,the pathological results,and polyp with the size were analyzed.Results The ratio of male with colorectal polyps was higher than female(male∶female=2.02∶1).The proportion of patients with left colon polyps was significantly higher than that of the right colon(64.6%v.s.25.7%).Among different pathological types,the detection rate of adenomatous polyps(86.1%)was higher than that of non-adenomatous polyps(13.9%).The detection rate of low-grade intraepithelial neoplasia in tubular adenoma(83.2%)was higher than that in other pathological types of low-grade intraepithelial neoplasia(P<0.001).The detection right colonpolyps in females were higher than that of males,and the detection rate of total intestinal polyps were significantly lower than that in males(P<0.05).The detection rate of pan-intestinal polyps in patients aged≥80 years(37.5%)was significantly higher than that in other age groups(P<0.05).The detection rate of neoplasia in inflammatory and hyperplastic polyps(5.9%)was signficantly lower than that of other types of polyps,and the degree of polyposis increased with the increase of villus content(P<0.05).The detection rate of neoplasia was significantly increased with the diameter(P<0.05).Conclusion The size of colorectal polyps and content of villus components are positively correlated with the polyposis,and it may provide new ideas for individualized screening and prevention of intestinal polyps and colorectal cancer in the future.
作者
田晓彤
卜淑蕊
Tian Xiaotong;Bu Shurui(Department of Gastroenterology,Jinshan Hospital Affiliated to Hehai University,Shanghai 201508,China)
出处
《临床内科杂志》
CAS
2022年第2期91-94,共4页
Journal of Clinical Internal Medicine
关键词
结直肠息肉
临床特征
Colorectal Polyps
Clinical Features
