摘要
目的:综合评价中医非药物治疗紧张型头痛的有效性。方法:计算机搜索2010年1月—2021年6月维普、万方、CNK、CBM、PubMed、EmBase、Cochrane图书馆、中国临床试验注册中心、美国临床试验注册中心的中医非药物治疗紧张性头痛的随机对照试验。客观评价文献质量,提取文献数据,采用RevMan5.3软件进行数据分析。结果:本研究共纳入符合标准的文献9篇,纳入病例629例。Meta结果显示:(1)总有效率:中医非药物治疗优于西医常规治疗[RR=1.25,95%Cl(1.16-1.35),P<0.00001];(2)发作次数:中医非药物治疗显著减少头痛发作次数,优于对照组[RR=-0.70,95%Cl(-1.07~-0.33),P=0.0002<0.05];(3)发作程度:中医非药物治疗显著缓解头痛发作程度,优于对照组[RR=-0.80,95%Cl(-1.09~-0.51),P<0.0001];(4)持续时间:中医非药物治疗显著减少头痛发作持续时间,优于对照组[RR=-0.52,95%Cl(-0.77~-0.27),P<0.0001]。结论:中医非药物治疗紧张型头痛临床有效率、发作次数、持续时间优于西医常规治疗。但由于纳入文献中核心期刊文献较少,多数研究方法未采用盲法,随机分组存在质量低下等情况,也可能存在发表偏倚,使本篇Meta分析结果可信度有所降低,上述结论仍需进一步大样本、高质量的随机双盲试验证实。
Objective:To compr ehensively evaluate the efficacy of non-drug traditional Chinese medicine in the treatment of tension headache.Methods:From January 2010 to June 2021,we searched VIP,Wanfang,CNK,CBM,PubMed,EmBase,Cochrane Library,China Clinical trial Registration Center and American Clinical trial Registration Center for non-drug randomized controlled trials of traditional Chinese medicine in the treatment of tension headache.Objective evaluation of literature quality,extraction of literature data,using RevMan5.3 software for data analysis.Results:A total of 9 articles in accordance with the criteria and 629 cases were included in this study.The results of Meta showed that the total effective rate of non-drug treatment of traditional Chinese medicine was better than that of routine treatment of western medicine[RR=1.25,95%Cl(1.16-1.35),P<0.00001],and the number of attacks of non-drug treatment of traditional Chinese medicine was significantly better than that of the control group[RR=-0.70,95%Cl(-1.07~-0.33),P=0.0002<0.05].The degree of pelvic attack:the degree of headache attack in the non-drug treatment group was significantly better than that in the con-trol group[RR=-0.80,95%Cl(-1.09~-0.51),P<0.0001],and the duration of elm:the duration of headache attack in the non-drug treatment group was significantly lower than that in the control group[RR=-0.52,95%Cl(-0.77~-0.27),P<0.0001].Conclusion:The clinical effective rate,attack times and duration of non-drug treatment of tension-type headache in traditional Chinese medicine is better than that of western medicine.However,due to the lack of core journals included in the literature,the blind method is not used in most research methods,the quality of random grouping is low,and there may also be publication bias,which reduces the credibility of the re-sults of this meta analysis.The above conclusions still need to be confirmed by a large sample,high-quality randomized double-blind trial.
作者
于海
朱林平
YU Hai;ZHU Lin-ping(Tianjin University of traditional Chinese medicine,Tianjin 301617,China;Tianjin Ninghe district hospital,Tianjin 301501,China;The Second Affiliated Hospital of Tianjin University of traditional Chinese medicine,Tianjin 300000,China)
出处
《内蒙古中医药》
2023年第2期36-39,92,共5页
Inner Mongolia Journal of Traditional Chinese Medicine
基金
国家中医药管理局第六批全国老中医药专家学术经验继承工作项目{国中医药人教发[2017]29号}
天津市卫生和健康委员会中医中西医科研课题项目(2017138)
天津市教育委员会科研计划项目(2018KJ017)
关键词
中医非药物疗法
紧张型头痛
META分析
随机对照
中医
Non-drug therapy of traditional Chinese medicine
Tension headache
Meta analysis
Randomized control
Traditional Chinese medicine
