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抗真菌性外耳道炎药物载体应用于真菌性外耳道炎的临床效果 被引量:9

Clinical effect of antifungal drugs supporter on fungal otitis externa
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摘要 目的观察抗真菌性外耳道炎药物载体应用于武警官兵真菌性外耳道炎的临床效果。方法选取武警河南总队医院2017-01至2020-12就诊的武警官兵真菌性外耳道炎患者85例(109耳),随机分为载体组和对照组。两组患者均首先清洁病变区域,并给予病变区域抗真菌软膏涂抹,完成治疗后,载体组置入抗真菌外耳道炎药物载体,对照组患者自行涂抹抗真菌软膏,每日1或2次。2周后复诊,比较两组疗效;比较两组6个月后复发率。结果对照组治疗总有效率为55.81%(24/43),明显低于载体组的95.23%(40/42),差异有统计学意义(P<0.05)。载体组复发率2.50%(1/40),对照组复发率29.17%(7/24),对照组复发率明显高于载体组,差异有统计学意义(P<0.05)。结论抗真菌性外耳道炎药物载体应用于武警官兵真菌性外耳道炎,可以提高疗效,值得临床推广应用。 Objective To observe the clinical effect of antifungal drugs supporter on fungal otitis externa.Methods Eighty-five patients with fungal otitis externa who were admitted to the hospital from January 2017 to December 2020 were randomly divided into two groups(treatment group and control group).The control group were applied with antifungal ointment by the patients themselves,while the treatment group were treated with antifungal drugs supporter.The curative effect was compared 2 weeks later and the recurrence rate was surveyed 6 months later.Results The total effective rates in the treatment group were significantly higher than those in the control group(95.23%vs.55.81%),and there was significant difference(P<0.05).The recurrence rate in the treatment group were lower than that in the control group(2.50%vs.29.17%),and there was also significant difference(P<0.05).Conclusions The clinical effect of antifungal drugs supporter which is clear in the treatment of fungal otitis externa is worthy of clinical application.
作者 张旭东 李楠 刘清源 王倩 郇颖静 张莉 ZHANG Xudong;LI Nan;LIU Qingyuan;WANG Qan;HUAN Yingjing;ZHANG Li(Department of Otolaryngology,Henan Provincial Corps Hospital of Chinese People’s Armed Police Force,Zhengzhou 450052,China;Department of Internal Medicine,Western Medical Branch of PLA General Hospital,Beijing 100000,China)
出处 《武警医学》 CAS 2022年第6期461-463,467,共4页 Medical Journal of the Chinese People's Armed Police Force
关键词 真菌性外耳道炎 抗真菌药物载体 复发 fungal otitis externa antifungal drugs supporter recurrence
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