摘要
目的探讨富细胞型子宫肌瘤的磁共振成像特点以及Ki-67表达情况。方法回顾性分析2018年12月~2019年11月在绍兴市妇幼保健院经手术病理证实的富细胞型子宫肌瘤患者42例,普通型子宫肌瘤患者84例作对照。用西门子1.5 T超导型MR扫描仪行常规T1WI、T2WI和DWI扫描。子宫肌瘤术后行免疫组化Ki-67检测。结果富细胞型子宫肌瘤在抑脂T2WI上呈高、稍高或等信号的占64.29%(27/42),而普通型子宫肌瘤占21.43%(18/84),差异有统计学意义(P<0.000);富细胞型子宫肌瘤在DWI上呈高、或稍高信号的占73.81%(31/42),而普通型子宫肌瘤占14.29%(12/84),差异有统计学意义(P<0.000);富细胞型子宫肌瘤Ki-67阳性率64.29%(27/42),而普通型子宫肌瘤为19.05%(16/84),差异有统计学意义(P<0.000)。结论富细胞型子宫肌瘤在MRI的抑脂T2WI及DWI上信号不同于普通型子宫肌瘤,且Ki-67多呈阳性表达。
Objective:To evaluate the MRI features of the cellular leiomyoma and to analyze the expression of Ki-67 in cellular leiomyoma.Methods:Forty-two cases of cellular leiomyoma and eighty-four cases of ordinary leiomyoma with MRI and pathology were analyzed from December 2018 to November 2019 in ShaoXing Women And Children Hospital.All of them were examed with Siemens avanto 1.5T super-conducting MR,plain scan were acquired with T1-weighted imaging,T2-weighted imaging and diffusion-weighted imaging.Compared the differences of MRI signal between the two groups.The expression of Ki-67 in different leiomyoma were detected by immunohistochemical methods.Results:Most cellular leiomyoma showed high,slightly high or equal signal on T2WI(27/42),while only 21.43%(18/84)of the ordinary leiomyoma showed the same signal,they had statistical difference(P<0.000).Most cellular leiomyoma showed high or slightly high signal on DWI(31/42),while only 14.29%(12/84)of the ordinary leiomyoma showed the same signal,they had statistical difference(P<0.000).The positive rate of Ki-67 expression was 64.29%(27/42)in cellular leiomyoma and was 19.05%(16/84)in ordinary leiomyoma,they had statistical difference(P<0.000).Conclusion:The signal features of cellular leiomyoma on conventional MRI(T2WI and DWI)were different from those of ordinary leiomyoma.And the expression of Ki-67 in cellular leiomyoma was higher than that in ordinary leiomyoma.
作者
李丽
夏阳
蒋宁
LI Li;XIA Yang;JIANG Ning(Shaoxing Women And Children Hospital,Zhejiang Shaoxing 312000)
出处
《中国优生与遗传杂志》
2020年第6期705-707,共3页
Chinese Journal of Birth Health & Heredity
