Marine biodiversity has emerged as a very promising resource of bioactive compounds and secondary metabolites from different sea organisms.The sponge’s secondary metabolites demonstrated various bioactivities and pot...Marine biodiversity has emerged as a very promising resource of bioactive compounds and secondary metabolites from different sea organisms.The sponge’s secondary metabolites demonstrated various bioactivities and potential pharmacological properties.This systematic review of the literature focuses on the advances achieved in the antioxidant potential of marine sponges in vitro.The review was performed in accordance with PRISMA guidelines.The main inclusion criterion for analysis was articles with identification of compounds from terpene classes that demonstrate antioxidant activity in vitro.Searching in three different databases,two hundred articles were selected.After screening abstracts,titles and evaluating for eligibility of manuscripts 14 articles were included.The most performed analyzes to detect antioxidant activity were scavenging activity 2,2-diphenyl-1-picrylhydrazyl(DPPH)and measurement of intracellular reactive oxygen species(ROS).It was possible to identify 17 compounds of the terpene class with pronounced antioxidant activity in vitro.Scientific evidence of the studies included in this review was accessed by the GRADE analysis.Terpenes play an important ecological role,moreover these molecules have a pharmaceutical and industrial application.展开更多
We revisit in this work a model for repeating Fast Radio Bursts based of the release of energy provoked by the magnetic field dynamics affecting a magnetar’s crust.We address the basics of such a model by solving the...We revisit in this work a model for repeating Fast Radio Bursts based of the release of energy provoked by the magnetic field dynamics affecting a magnetar’s crust.We address the basics of such a model by solving the propagation of the perturbation approximately,and quantify the energetics and the radiation by bunches of charges in the so-called charge starved region in the magnetosphere.The(almost)simultaneous emission of newly detected X-rays from SGR 1935+2154 is tentatively associated with a reconnection behind the propagation.The strength of f-mode gravitational radiation excited by the event is quantified,and more detailed studies of the nonlinear(spiky)soliton solutions are suggested.展开更多
基金the FAPESP(Fundação de AmparoàPesquisa do Estado de São Paulo)A.C.M.R(2019/10228-5)A.C.C.A.(2019/19708-0).FAPEG(Fundação de AmparoàPesquisa do Estado de Goiás)L.R.F.S(202110267000075).
文摘Marine biodiversity has emerged as a very promising resource of bioactive compounds and secondary metabolites from different sea organisms.The sponge’s secondary metabolites demonstrated various bioactivities and potential pharmacological properties.This systematic review of the literature focuses on the advances achieved in the antioxidant potential of marine sponges in vitro.The review was performed in accordance with PRISMA guidelines.The main inclusion criterion for analysis was articles with identification of compounds from terpene classes that demonstrate antioxidant activity in vitro.Searching in three different databases,two hundred articles were selected.After screening abstracts,titles and evaluating for eligibility of manuscripts 14 articles were included.The most performed analyzes to detect antioxidant activity were scavenging activity 2,2-diphenyl-1-picrylhydrazyl(DPPH)and measurement of intracellular reactive oxygen species(ROS).It was possible to identify 17 compounds of the terpene class with pronounced antioxidant activity in vitro.Scientific evidence of the studies included in this review was accessed by the GRADE analysis.Terpenes play an important ecological role,moreover these molecules have a pharmaceutical and industrial application.
基金financial support.J.E.H.has been supported by the CNPq Agency(Brazil)the FAPESP foundation(S?o Paulo,Brazil)。
文摘We revisit in this work a model for repeating Fast Radio Bursts based of the release of energy provoked by the magnetic field dynamics affecting a magnetar’s crust.We address the basics of such a model by solving the propagation of the perturbation approximately,and quantify the energetics and the radiation by bunches of charges in the so-called charge starved region in the magnetosphere.The(almost)simultaneous emission of newly detected X-rays from SGR 1935+2154 is tentatively associated with a reconnection behind the propagation.The strength of f-mode gravitational radiation excited by the event is quantified,and more detailed studies of the nonlinear(spiky)soliton solutions are suggested.
