A chronic liver disease usually results in iron accumulation, and an excess of iron will further aggravate liver injury, forming a vicious circle. Likewise, it also plays a significant role in other organs when it com...A chronic liver disease usually results in iron accumulation, and an excess of iron will further aggravate liver injury, forming a vicious circle. Likewise, it also plays a significant role in other organs when it comes to iron metabolism. A long time passes between the time it takes to break through to MRIbased iron diagnosis and its ability to distinguish the types of iron accumulation accurately and quickly.This work highlighted a new type of iron accumulation treatment solution integrated with diagnosis and treatment. A chelating method for ICG and Leci that can assist PAI and MRI to achieve better diagnostic and therapeutic effects. This work revealed biomaterial engineering techniques are being adapted to address clinical medical problems through cutting-edge research.展开更多
基金supported by the Major State Basic Research Development Program of China (No. 2017YFA0205201)the National Natural Science Foundation of China (Nos. 81925019 and U1705281)+2 种基金the Fundamental Research Funds for the Central Universities (Nos. 20720190088 and 20720200019)the China Postdoctoral Science Foundation (Nos. 2020TQ0181 and 2021M690096)the Program for New Century Excellent Talents in University, China (No. NCET-13-0502)。
文摘A chronic liver disease usually results in iron accumulation, and an excess of iron will further aggravate liver injury, forming a vicious circle. Likewise, it also plays a significant role in other organs when it comes to iron metabolism. A long time passes between the time it takes to break through to MRIbased iron diagnosis and its ability to distinguish the types of iron accumulation accurately and quickly.This work highlighted a new type of iron accumulation treatment solution integrated with diagnosis and treatment. A chelating method for ICG and Leci that can assist PAI and MRI to achieve better diagnostic and therapeutic effects. This work revealed biomaterial engineering techniques are being adapted to address clinical medical problems through cutting-edge research.
