The development of tissue engineering and regeneration research has created new platforms for bone transplantation.However,the preparation of scaffolds with good fiber integrity is challenging,because scaffolds prepar...The development of tissue engineering and regeneration research has created new platforms for bone transplantation.However,the preparation of scaffolds with good fiber integrity is challenging,because scaffolds prepared by traditional printing methods are prone to fiber cracking during solvent evaporation.Human skin has an excellent natural heat-management system,which helps to maintain a constant body temperature through perspiration or blood-vessel constriction.In this work,an electrohydrodynamic-jet 3D-printing method inspired by the thermal-management system of skin was developed.In this system,the evaporation of solvent in the printed fibers can be adjusted using the temperature-change rate of the substrate to prepare 3D structures with good structural integrity.To investigate the solvent evaporation and the interlayer bonding of the fibers,finite-element analysis simulations of a three-layer microscale structure were carried out.The results show that the solvent-evaporation path is from bottom to top,and the strain in the printed structure becomes smaller with a smaller temperaturechange rate.Experimental results verified the accuracy of these simulation results,and a variety of complex 3D structures with high aspect ratios were printed.Microscale cracks were reduced to the nanoscale by adjusting the temperature-change rate from 2.5 to 0.5℃s-1.Optimized process parameters were selected to prepare a tissue engineering scaffold with high integrity.It was confirmed that this printed scaffold had good biocompatibility and could be used for bone-tissue regeneration.This simple and flexible 3D-printing method can also help with the preparation of a wide range of micro-and nanostructured sensors and actuators.展开更多
The deformation characteristics of silty soils under vibrational loads can easily change due to the wetting process,leading to the failure of roadbed structures.Commonly used methods for improving silty soils in engin...The deformation characteristics of silty soils under vibrational loads can easily change due to the wetting process,leading to the failure of roadbed structures.Commonly used methods for improving silty soils in engineering often yield unsatisfactory economic and ecological outcomes.As an environment-friendly soil improvement material,Xanthan gum has broad application prospects and is therefore considered a solidifying agent for enhancing silty soil properties in the Yellow River Basin.In this study,a series of tests is conducted using a scanning electron microscope and a dynamic triaxial testing apparatus to investigate the microstructure and dynamic deformation characteristics of unsaturated silty soil with varying xanthan gum contents during the wetting process.The results show that xanthan gum effectively fills voids between soil particles and adheres to their surfaces,forming fibrous and network structures.This modification enhances the inherent properties of the silty soil and significantly improves its stability under dynamic loading.Specifically,with increasing xanthan gum content,the dynamic shear modulus increases while the damping ratio decreases.During the wetting process,as suction decreases,the dynamic shear modulus decreases while the damping ratio increases.Xanthan gum reduces the sensitivity of the dynamic deformation characteristics of the treated silty soil to changes in suction levels.Finally,based on the modified Hardin-Drnevich hyperbolic model,a predictive model for the dynamic shear modulus and damping ratio of treated silty soil is proposed,considering the xanthan gum content.These research findings provide a theoretical basis for the construction and maintenance of water conservancy,slope stabilization,and roadbed projects in the Yellow River Basin.展开更多
In this study,to simulate open channel flows,an explicit incompressible mesh-free method is employed in which the pressure field is obtained by explicitly solving the pressure Poisson equation.To capture the velocity ...In this study,to simulate open channel flows,an explicit incompressible mesh-free method is employed in which the pressure field is obtained by explicitly solving the pressure Poisson equation.To capture the velocity information in open channel flows,the source term in the pressure Poisson equation is modified while the spatial discretization of gradient and Laplacian models is based on the moving particle semi-implicit(MPS)method.The inflow boundary condition is treated by injecting fluid particles into the domain according to the inlet discharge,and the outflow condition is handled by prescribing the pressure distribution and removing the fluid particles beyond the domain.The explicit incompressible mesh-free method is then used to simulate open channel flows,including weir flow,hydraulic jump,and flow over an obstacle.In the simulations,velocity distribution and flow pattern are examined.The simulated results are compared to available experimental measurements and other numerical results.There is a good agreement between the simulated results and the experimental measurements.It shows that the explicit incompressible mesh-free method can reproduce the flow characteristics in the open channel flows.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.52105577)the Natural Science Foundation of Zhejiang Province(Grant Nos.LQ22E050001 and LQ21E080007)+1 种基金the Natural Science Foundation of Ningbo(Grant Nos.2021J088 and 2023J376)the Ningbo Yongjiang Talent Introduction Program(Grant No.2021A-137-G).
文摘The development of tissue engineering and regeneration research has created new platforms for bone transplantation.However,the preparation of scaffolds with good fiber integrity is challenging,because scaffolds prepared by traditional printing methods are prone to fiber cracking during solvent evaporation.Human skin has an excellent natural heat-management system,which helps to maintain a constant body temperature through perspiration or blood-vessel constriction.In this work,an electrohydrodynamic-jet 3D-printing method inspired by the thermal-management system of skin was developed.In this system,the evaporation of solvent in the printed fibers can be adjusted using the temperature-change rate of the substrate to prepare 3D structures with good structural integrity.To investigate the solvent evaporation and the interlayer bonding of the fibers,finite-element analysis simulations of a three-layer microscale structure were carried out.The results show that the solvent-evaporation path is from bottom to top,and the strain in the printed structure becomes smaller with a smaller temperaturechange rate.Experimental results verified the accuracy of these simulation results,and a variety of complex 3D structures with high aspect ratios were printed.Microscale cracks were reduced to the nanoscale by adjusting the temperature-change rate from 2.5 to 0.5℃s-1.Optimized process parameters were selected to prepare a tissue engineering scaffold with high integrity.It was confirmed that this printed scaffold had good biocompatibility and could be used for bone-tissue regeneration.This simple and flexible 3D-printing method can also help with the preparation of a wide range of micro-and nanostructured sensors and actuators.
基金supported by the Postgraduate Education Reform and Quality Improvement Project of Henan Province,China(Grant No.YJS2023AL004)the Graduate Innovation Project of North China University of Water Resources and Electric Power(Grant No.NCWUYC-202315069)the China National Scholarship Fund organized by the China Scholarship Council(Grant No.202208410337).
文摘The deformation characteristics of silty soils under vibrational loads can easily change due to the wetting process,leading to the failure of roadbed structures.Commonly used methods for improving silty soils in engineering often yield unsatisfactory economic and ecological outcomes.As an environment-friendly soil improvement material,Xanthan gum has broad application prospects and is therefore considered a solidifying agent for enhancing silty soil properties in the Yellow River Basin.In this study,a series of tests is conducted using a scanning electron microscope and a dynamic triaxial testing apparatus to investigate the microstructure and dynamic deformation characteristics of unsaturated silty soil with varying xanthan gum contents during the wetting process.The results show that xanthan gum effectively fills voids between soil particles and adheres to their surfaces,forming fibrous and network structures.This modification enhances the inherent properties of the silty soil and significantly improves its stability under dynamic loading.Specifically,with increasing xanthan gum content,the dynamic shear modulus increases while the damping ratio decreases.During the wetting process,as suction decreases,the dynamic shear modulus decreases while the damping ratio increases.Xanthan gum reduces the sensitivity of the dynamic deformation characteristics of the treated silty soil to changes in suction levels.Finally,based on the modified Hardin-Drnevich hyperbolic model,a predictive model for the dynamic shear modulus and damping ratio of treated silty soil is proposed,considering the xanthan gum content.These research findings provide a theoretical basis for the construction and maintenance of water conservancy,slope stabilization,and roadbed projects in the Yellow River Basin.
基金This work was supported by the Key Research and Development Program of Zhejiang Province(Grant No.2020C03082)the Visiting Researcher Fund Program of State Key Laboratory of Water Resources and Hydropower Engineering Science,Wuhan University(Grant No.2021HLG01).
文摘In this study,to simulate open channel flows,an explicit incompressible mesh-free method is employed in which the pressure field is obtained by explicitly solving the pressure Poisson equation.To capture the velocity information in open channel flows,the source term in the pressure Poisson equation is modified while the spatial discretization of gradient and Laplacian models is based on the moving particle semi-implicit(MPS)method.The inflow boundary condition is treated by injecting fluid particles into the domain according to the inlet discharge,and the outflow condition is handled by prescribing the pressure distribution and removing the fluid particles beyond the domain.The explicit incompressible mesh-free method is then used to simulate open channel flows,including weir flow,hydraulic jump,and flow over an obstacle.In the simulations,velocity distribution and flow pattern are examined.The simulated results are compared to available experimental measurements and other numerical results.There is a good agreement between the simulated results and the experimental measurements.It shows that the explicit incompressible mesh-free method can reproduce the flow characteristics in the open channel flows.
