On the occasion of the additional issue of the CONTAINERIZATION, I’d like to express my sincere appreciation to the readers and authors both at home and abroad on behalf of the CONTAINERIZATION. The container transpo...On the occasion of the additional issue of the CONTAINERIZATION, I’d like to express my sincere appreciation to the readers and authors both at home and abroad on behalf of the CONTAINERIZATION. The container transport in China is booming with leaps and bounds and the CONTAINERIZATION is becoming prosperous with each passing day. With the concern, support and help of the Ministry of Communications, Shanghai News Publication展开更多
Background: While causing a financial and economic loss in many countries in a few months, COVID 19 was of great impact on public health. The Iraqi government took several measures since the first Iraqi case was disco...Background: While causing a financial and economic loss in many countries in a few months, COVID 19 was of great impact on public health. The Iraqi government took several measures since the first Iraqi case was discovered in February 2020. One of the fundamental measures to control this pandemic is social isolation, which depends greatly on people’s awareness to decrease the incidence of COVID-19. Objectives: To study the COVID-19-effect on dentists’ social life and their future plan, and to find the relation between that effect and some dentists’ demographic variables. Methods: A cross-sectional study was conducted from 2nd January to 7th May 2021, by an electronic version of the questionnaire through Google form. With facilitating orders delivered to all the specialist dental centers for adults of Al-Resafa health directorate;any dentists working in specialist dental centers for adults of Al-Resafa health directorate, and accept to participate in this study. Results: A total of 10 specialist dental centers for adults of the Al-Resafa health directorate represent 566/628 dentists enrolled in this study with a response rate of 88.99%. Most of them aged less than 30 years old (62.2%), female (60.6%), married status (50.4%), had 1 - 3 children (71.91%), Rotator (51.1%), with less than five years of experience (61.3%). Conclusion: COVID-19 affected so many aspects of health workers’ lives including dentists. About two-thirds of dentists had negative feelings, of which almost all had anxiety. Younger ages, females, married and having children are factors that contribute to the affection of dental social lives more than other categories.展开更多
In this editorial,I comment on the article by Zhang et al.To emphasize the importance of the topic,I discuss the relationship between the use of smart medical devices and mental health.Smart medical services have the ...In this editorial,I comment on the article by Zhang et al.To emphasize the importance of the topic,I discuss the relationship between the use of smart medical devices and mental health.Smart medical services have the potential to positively influence mental health by providing monitoring,insights,and inter-ventions.However,they also come with challenges that need to be addressed.Understanding the primary purpose for which individuals use these smart tech-nologies is essential to tailoring them to specific mental health needs and prefe-rences.展开更多
This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signa...This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signals and degrade positioning accuracy.Managed by the Indonesian Geospatial Information Agency(BIG),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 GNSS receivers spanning equatorial to southern low-latitude regions.Ina-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast Asia.We provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this network.We generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific research.Two preliminary findings from the ROTI maps of Ina-CORS are noteworthy.First,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther eastward.Second,we demonstrate that combined ROTI maps from Ina-CORS and GNSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East Asia.We have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the G5 Geomagnetic Storm on May 11,2024.We observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities post-midnight.By sharing ROTI maps from Indonesia and integrating them with regional GNSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionospheric research.展开更多
BACKGROUND Monkeypox(Mpox),is a disease of global public health concern,as it does not affect only countries in western and central Africa.AIM To assess Burundi healthcare workers(HCWs)s’level of knowledge and confid...BACKGROUND Monkeypox(Mpox),is a disease of global public health concern,as it does not affect only countries in western and central Africa.AIM To assess Burundi healthcare workers(HCWs)s’level of knowledge and confidence in the diagnosis and management of Mpox.METHODS We conducted a cross-sectional study via an online survey designed mainly from the World Health Organization course distributed among Burundi HCWs from June-July 2023.The questionnaire comprises 8 socioprofessional-related questions,22 questions about Mpox disease knowledge,and 3 questions to assess confidence in Mpox diagnosis and management.The data were analyzed via SPSS software version 25.0.A P value<0.05 was considered to indicate statistical significance.RESULTS The study sample comprised 471 HCWs who were mainly medical doctors(63.9%)and nurses(30.1%).None of the 22 questions concerning Mpox knowledge had at least 50%correct responses.A very low number of HCWs(17.4%)knew that Mpox has a vaccine.The confidence level to diagnose(21.20%),treat(18.00%)or prevent(23.30%)Mpox was low among HCWs.The confidence level in the diagnosis of Mpox was associated with the HCWs’age(P value=0.009),sex(P value<0.001),work experience(P value=0.002),and residence(P value<0.001).The confidence level to treat Mpox was significantly associated with the HCWs’age(P value=0.050),sex(P value<0.001),education(P value=0.033)and occupation(P value=0.005).The confidence level to prevent Mpox was associated with the HCWs’education(P value<0.001),work experience(P value=0.002),residence(P value<0.001)and type of work institution(P value=0.003).CONCLUSION This study revealed that HCWs have the lowest level of knowledge regarding Mpox and a lack of confidence in the ability to diagnose,treat or prevent it.There is an urgent need to organize continuing medical education programs on Mpox epidemiology and preparedness for Burundi HCWs.We encourage future researchers to assess potential hesitancy toward Mpox vaccination and its associated factors.展开更多
This study was conducted at Fafan Research Center, Golajo research site to evaluate the effect of Moringa stenopetala and pigeon pea leaf supplementation on growth performance of short-eared Somali goat breed. A total...This study was conducted at Fafan Research Center, Golajo research site to evaluate the effect of Moringa stenopetala and pigeon pea leaf supplementation on growth performance of short-eared Somali goat breed. A total of fifteen yearling indigenous short-eared Somali goat breeds with an initial weight of 15.2 ± 0.30 kg were assigned to three treatment groups using completely randomized design. Pigeon pea (Pp) and Moringa stenopetala (MS) feeds were formulated using 0%, 5%, and 10% inclusion levels of MSLM and PPLM as experimental diets, respectively. The feed of the experiment was prepared in two levels (2 kg of Moringa stenopetala and 2 kg of pigeon pea) and was supplemented to experimental animals in treatments one and two, respectively. The average e initial body weight of selected male goats was 18.82 ± 0.37, 18.8 ± 0.37 and 17.8 ± 0.37 kg under treatment groups T1, T2 and control respectively. Data was analyzed using general linear model (GLM) procedure of SAS computer package Version 9.0 (SAS, 2002). The final weights gain (FWG) of goats on T1 and T2 of experimental group was significantly (P 0.05) the final weight gain of goat supplemented on Moringa stenopetala (T1) and pigeon pea levels (T2). The mean average weight gains (AWG) obtained from the supplemented group in this study were 7.50 ± 0.37 and 7.82 ± 0.37 kg for T1 and T2, whereas mean weight gains for un-supplemented goats were found to be 6.26 ± 0.37 kg. Feeding of dried Moringa stenopetala and pigeon pea leaves mixture improved body weights and average daily body weight gain without affecting feed intake and overall health of Somali goat breed. As Moringa stenopetala and pigeon pea leaves are rich nitrogen/protein source, they can be used effectively as substitute for conventional concentrate in the diet of growing goats at small holder farmer’s level where they can be grown in abundance. Therefore, for higher quality of forage and higher total DM yield for animal feeding, moringa should be harvested at wider harvesting intervals of at least 6th- to 8th-week intervals. Similarly, for pigeon peas, 4- to 6-week harvesting interval can result in optimum forage as well as feed quality and resulted in better growth performances for Somali short-eared goat breeds.展开更多
Muscle deconditioning due to hospitalisation is problematic, causing delayed discharges, more nursing, carer, or social service support following discharge, and possible discharge to a care home rather than the patien...Muscle deconditioning due to hospitalisation is problematic, causing delayed discharges, more nursing, carer, or social service support following discharge, and possible discharge to a care home rather than the patient’s own home. Muscle deconditioning is associated with increased mortality, infections, depression, and reductions in patient mobility and ability to engage in their activities of daily living. Preserving muscle strength and function should form part of patients’ rehabilitation plans. Progressive resistance training (PRE) offers the most cost-effective way of preserving muscle strength and function;however, it is not routinely carried out in hospitals. A leg strengthening device (the S-Press) has been developed with the aim of improving access to effective PRE for adults. Using a qualitative approach, thematic analysis of interviews with physiotherapists, patients, and relative carers about their experience of using the S-Press provided insight into integrating PRE into patients’ rehabilitation, what promoted or prevented its use, and the outcomes associated with its use. Four overall themes emerged from the data. “Experience of Users” described that the S-Press was accessible, convenient, time efficient, portable, and manoeuvrable, and it provided an objective measure of progress. “Facilitators” included findings around how the S-Press was easy to use, motivational, and comfortable when in use. “Barriers” comprised the inability of some patients to use the S-Press independently and the identification of obstacles that prevented consistent use. “Impact and Benefits” represented the perceptions of increased leg strength and psychological benefits. The S-Press is beneficial for patients’ rehabilitation by offering PRE that is simple and easy to use, acceptable to both patients and professionals, and can be integrated as part of patients’ rehabilitation plans.展开更多
Fever is the primary reason for consultation and admission to pediatric emergency departments. The aim of this study was to describe the clinical, etiological and prognostic aspects of acute fever in children aged 0 -...Fever is the primary reason for consultation and admission to pediatric emergency departments. The aim of this study was to describe the clinical, etiological and prognostic aspects of acute fever in children aged 0 - 15 years. Patients and Methods: This was a prospective cross-sectional study from April 1, 2021 to March 31, 2022 and affected all children aged 0 to 15 years old with a temperature of 39˚C or higher (≥), having less than five days and hospitalized in the pediatric department of the Gabriel Touré University Hospital. Results: During the study period, 150 children were included, the sex-ratio was 0.85. Children aged 0 - 5 years represented 71.4% of the sample. References represented more than half of the sample, or 58% of cases. Body temperature was above 40˚C in 18.7% of cases. Functional signs were dominated by respiratory signs in 28% and digestive signs in 18%. Clinical pallor was found in 55.3% of children associated with signs of respiratory struggle in 70% of cases and tachycardia in 40% of patients. Anemia was present in 65.3% of patients. Hyperleucocytosis and leukopenia were found in 45.3% and 43.3% of patients respectively. The C-reactive protein was positive in 44.7% of patients and Cytobacteriological Examination and Chemistry of Cerebrospinal Fluid was positive in 8.7% of cases. The thick drop was positive in 44.7% of patients and blood cultures grew in 6 patients. Etiology was dominated by severe malaria 54 cases (36%), pneumonia (19.3%), meningitis (12.6%), and in those under one month it was bacterial neonatal infection (8.6%). In our study, slightly more than one patient out of three died during hospitalization, 36% (54 cases/150) and among these 70% (38 cases/54) were under 5 years old. The most lethal pathologies were severe malaria (36%), bacterial pneumonia (19.3%), meningitis (12.6%), bacterial neonatal infections (8.6%) and measles complicated by pneumonia (5.3%). Mortality during hospitalization was 36% of deaths (54 out of 150 patients) and 70.3% (38/54) of the deceased patients were under 5 years old. Conclusion: This study shows that fever is a frequent symptom and a sign of serious and very lethal pathologies. The cause of fever can be a diagnostic challenge for health workers. However, early identification of children at risk for serious illness could allow for prompt and appropriate management in appropriate settings.展开更多
BACKGROUND Although breast milk is ideal for newborns,in some cases,it is replaced with cow’s milk,which contains proteins that increase the risk of cow’s milk protein allergy(CMPA).AIM To evaluate CMPA prevalence i...BACKGROUND Although breast milk is ideal for newborns,in some cases,it is replaced with cow’s milk,which contains proteins that increase the risk of cow’s milk protein allergy(CMPA).AIM To evaluate CMPA prevalence in Bahrain and compare clinical characteristics of children with immunoglobulin E(IgE)-and non-IgE-mediated CMPA.METHODS This retrospective cohort study examined children with CMPA diagnosed at the pediatric gastroenterology outpatient clinic of the Salmaniya Medical Complex,Bahrain,between 2014 and 2022,and assessed CMPA prevalence.Clinical presentations,laboratory findings,dietary modifications,and outcomes were compared between children with IgE-mediated and non-IgE-mediated CMPA.Categorical variables were compared using Fisher’s exact test or Pearson’sχ2 test,whereas continuous variables were compared using Student’s t-test or the Mann-Whitney U test.RESULTS Of 8332 patients,6022(72.3%)adhered to their appointment.Of them,618(10.3%)were suggested of having CMPA and 595(96.3%)were included;CMPA prevalence was 2%.Most patients were Bahraini(93.8%)and males(55.3%).Non-IgE-mediated type accounted for 77.3%cases and IgE-mediated type,22.7%.IgE-mediated CMPA presented more in boys(P=0.030),and later in life(5.1 months±4.5 months vs 4.2 months±4.2 months,P=0.016,95%CI:0.08-1.73),had more associated diseases(P<0.001);and presented with more cutaneous(P=0.024)and respiratory(P=0.003)manifestations,severe symptoms[rash/dry skin(P=0.031),facial swelling/angioedema(P=0.003),failure to thrive(P=0.013),apparent life-threatening event(P<0.001)],and positive physical findings(P=0.002)than non-IgE-mediated CMPA.Most patients were exclusively fed cow milk formula(50.3%).The amino acid-based formula(AAF)was most prescribed(60.5%)with no difference between the two types(P=0.173).Although breastfeeding was recommended to 49.6%,only 8.2%were exclusively breastfed.IgE-mediated CMPA was associated with a longer follow-up duration than non-IgE-mediated CMPA(17.3 months±14.0 months vs 13.5 months±13.4 months,P=0.005,95%CI:1.1-6.3).CONCLUSION This study revealed a high CMPA prevalence with clinical differences between both types that can influence treatment.AAF was most prescribed,while breastfeeding with dietary modification is rarely applied.展开更多
Over the last few decades, dengue fever epidemics have increased in frequency and intensity worldwide, making it a major global concern for public health. Its prevention, which is essentially vector-based control, is ...Over the last few decades, dengue fever epidemics have increased in frequency and intensity worldwide, making it a major global concern for public health. Its prevention, which is essentially vector-based control, is already being compromised by reports of resistance of the main vector Aedes aegypti to insecticides. To tackle the rapid increase in insecticide resistance and outbreaks, the biological vector control is a promising approach. One of the strategies of this approach is the use of entomopathogenic fungi because of their great efficacy and their eco-friendly aspects. However, some aspects of their use, such as the low efficiency, the high cost of production and the sensitivity to various adverse conditions, need to be addressed for their successful large-scale application. Therefore, innovative technologies based on strains of transgenic fungi with improved biocontrol potentials by genetic engineering are actively pursued. Although these modified mycoinsecticides are acclaimed for their better effectiveness against target insects, the main concern remains their potential adverse effects on the environment and human health. The present review is dedicated to giving an update on recent developments in transgenic entomopathogenic fungi (TEF) for Aedes mosquito control. Future perspectives are also proposed to address the safety concerns related to the release of transgenic entomopathogenic fungi into the environment.展开更多
Pancreatic cancer is usually associated with a poor prognosis.Surgery is the main curative treatment but pancreatic operations are aggressive and new tools that help clinicians to predict surgical and prognostic outco...Pancreatic cancer is usually associated with a poor prognosis.Surgery is the main curative treatment but pancreatic operations are aggressive and new tools that help clinicians to predict surgical and prognostic outcomes are necessary.Lu et al recently published a retrospective,single centre cohort study evaluating the impact of seven nutritional and inflammatory markers in pancreatic cancer surgical patients:The albumin-to-globulin ratio,prognostic nutritional index(PNI),systemic immune-inflammation index(SII),neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),nutritional risk index,and the geriatric nutritional risk index.A significant correlation was found between the PNI,SII,NLR,and PLR and a hospital discharge of less than 15 days.In a univariable analysis,PNI,SII,NLR and PLR were significantly related to recurrence-free survival and,in a multivariable analysis PNI was associated with overall survival.Various meta-analyses corroborate the results in terms of prognosis but individual studies are discordant on their usefulness.Besides,the cut-off values for these markers vary significantly between studies and there are no clinical trials comparing them to identify the most relevant ones.These are limitations when implementing nutritional and inflammatory biomarkers into clinical practice and further studies are needed in order to answer these questions.展开更多
Introduction: The WHO’s measles control strategy is based on epidemiological surveillance and vaccination. Little is currently known about the performance of the surveillance system, particularly in outlying areas. I...Introduction: The WHO’s measles control strategy is based on epidemiological surveillance and vaccination. Little is currently known about the performance of the surveillance system, particularly in outlying areas. It is in this context that the present study was carried out to evaluate the measles epidemiological surveillance system in the Kangaba health district. Method: This was a descriptive cross-sectional study with retrospective data collection for the period from 1 January to 31 December 2022 in the Kangaba health district with 18 epidemiological surveillance officers. Data were collected using an observation grid and documentary analysis. Results: We found a simplicity of 97%, a representativeness of 95% and a reactivity of 53%. Not all notified cases were sampled (64%). Of the 17 CSCom, 8 were positive. A total of 34 confirmed cases of measles were recorded, with one death. Conclusion: Overall, the system is functional and well-established in the health centres, but it remains important to ensure that suspected cases are investigated and that the time between sampling and the availability of laboratory results is respected.展开更多
Chronic kidney disease(CKD),which represents a significant global health concern,is characterized by a gradual decline in kidney function,leading to complications such as electrolyte imbalance,cardiovascular disease,a...Chronic kidney disease(CKD),which represents a significant global health concern,is characterized by a gradual decline in kidney function,leading to complications such as electrolyte imbalance,cardiovascular disease,and immune dysfunction.Standard CKD management includes dietary modifications,ketoana-logues supplementation,blood pressure and blood glucose control,hydration maintenance,and treatment of the underlying causes.Emerging evidence has indicated a significant role of the gut microbiota in CKD,and that dysbiosis of the gut microbiota contributes to the progression of CKD towards end-stage renal disease.Probiotics and prebiotics have recently garnered attention owing to their potential to enhance gastrointestinal health and well-being by restoring the balance of the gut microbiota.Specific probiotic strains,including Lactobacillus and Bifidobacterium,promote beneficial bacterial growth,suppress harmful bacteria,and exert anti-inflammatory,antihypertensive,and antidiabetic effects.The combination of Streptococcus thermophilus,Lactobacillus acidophilus,Bifidobacterium longum,and Bacillus coagulans has demonstrated potential as a therapeutic formulation for CKD management in various studies,highlighting its promise in treating CKD;however,supporting evidence remains limited,making it crucial to conduct further investigations to determine the specific effects of different probiotic formulations on outcomes in patients with CKD.展开更多
The integration of digital tools and effective knowledge management practices is critical for enhancing administrative efficiency and institutional continuity in higher education. This study investigates the relations...The integration of digital tools and effective knowledge management practices is critical for enhancing administrative efficiency and institutional continuity in higher education. This study investigates the relationships between knowledge modeling, institutional memory, leadership styles, technology, and administrative efficiency at the University of Cape Coast (UCC). The study sought to identify the challenges and opportunities in integrating digital tools into administrative processes and to provide actionable recommendations for improvement. A mixed-methods research design was employed, combining quantitative analysis using Partial Least Squares Structural Equation Modeling (PLS-SEM) with qualitative thematic analysis of interviews. The findings revealed key challenges, including resistance to change, fragmented knowledge repositories, and inadequate funding, alongside opportunities such as centralized knowledge systems, cost-effective open-source tools, and capacity-building initiatives. The study highlights the importance of strategic leadership, robust policies, and investments in digital infrastructure to enhance administrative practices. Policy implications include the need for clear digital transformation guidelines and leadership training to foster innovation and collaboration. Recommendations include investing in scalable digital tools, implementing comprehensive capacity-building programs, and promoting stakeholder engagement to drive successful digital integration. These insights provide a roadmap for UCC and similar institutions seeking to optimize administrative efficiency through digital transformation.展开更多
The year 2025 marks the 75th anniversary of the establishment of diplomatic relations between China and Vietnam and the China-Vietnam People-to-People Exchange Year.Over the last 75 years,China has always regarded Vie...The year 2025 marks the 75th anniversary of the establishment of diplomatic relations between China and Vietnam and the China-Vietnam People-to-People Exchange Year.Over the last 75 years,China has always regarded Vietnam as a priority in its neighborhood diplomacy,and Vietnam has regarded its relations with China as the top priority in its independent,all-round,and diversified foreign policy.The two sides have continuously strengthened mutually beneficial cooperation in various fields and elevated their comprehensive strategic partnership to new heights to build a China-Vietnam community with a shared future with strategic significance.展开更多
文摘On the occasion of the additional issue of the CONTAINERIZATION, I’d like to express my sincere appreciation to the readers and authors both at home and abroad on behalf of the CONTAINERIZATION. The container transport in China is booming with leaps and bounds and the CONTAINERIZATION is becoming prosperous with each passing day. With the concern, support and help of the Ministry of Communications, Shanghai News Publication
文摘Background: While causing a financial and economic loss in many countries in a few months, COVID 19 was of great impact on public health. The Iraqi government took several measures since the first Iraqi case was discovered in February 2020. One of the fundamental measures to control this pandemic is social isolation, which depends greatly on people’s awareness to decrease the incidence of COVID-19. Objectives: To study the COVID-19-effect on dentists’ social life and their future plan, and to find the relation between that effect and some dentists’ demographic variables. Methods: A cross-sectional study was conducted from 2nd January to 7th May 2021, by an electronic version of the questionnaire through Google form. With facilitating orders delivered to all the specialist dental centers for adults of Al-Resafa health directorate;any dentists working in specialist dental centers for adults of Al-Resafa health directorate, and accept to participate in this study. Results: A total of 10 specialist dental centers for adults of the Al-Resafa health directorate represent 566/628 dentists enrolled in this study with a response rate of 88.99%. Most of them aged less than 30 years old (62.2%), female (60.6%), married status (50.4%), had 1 - 3 children (71.91%), Rotator (51.1%), with less than five years of experience (61.3%). Conclusion: COVID-19 affected so many aspects of health workers’ lives including dentists. About two-thirds of dentists had negative feelings, of which almost all had anxiety. Younger ages, females, married and having children are factors that contribute to the affection of dental social lives more than other categories.
文摘In this editorial,I comment on the article by Zhang et al.To emphasize the importance of the topic,I discuss the relationship between the use of smart medical devices and mental health.Smart medical services have the potential to positively influence mental health by providing monitoring,insights,and inter-ventions.However,they also come with challenges that need to be addressed.Understanding the primary purpose for which individuals use these smart tech-nologies is essential to tailoring them to specific mental health needs and prefe-rences.
基金JSPS KAKENHI Grant Number16H06286 supports global GNSS ionospheric maps (TEC,ROTI,and detrended TEC maps) developed by the Institute for SpaceEarth Environmental Research (ISEE) of Nagoya Universitysupport of the 2024 JASSO Follow-up Research Fellowship Program for a 90-day visiting research at the Institute for Space-Earth Environmental Research (ISEE),Nagoya University+3 种基金the support received from Telkom University under the“Skema Penelitian Terapan Periode I Tahun Anggaran 2024”the Memorandum of Understanding for Research Collaboration on Regional Ionospheric Observation (No:092/SAM3/TE-DEK/2021)the National Institute of Information and Communications Technology (NICT) International Exchange Program 2024-2025(No.2024-007)support for a one-year visiting research at Hokkaido University
文摘This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signals and degrade positioning accuracy.Managed by the Indonesian Geospatial Information Agency(BIG),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 GNSS receivers spanning equatorial to southern low-latitude regions.Ina-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast Asia.We provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this network.We generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific research.Two preliminary findings from the ROTI maps of Ina-CORS are noteworthy.First,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther eastward.Second,we demonstrate that combined ROTI maps from Ina-CORS and GNSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East Asia.We have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the G5 Geomagnetic Storm on May 11,2024.We observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities post-midnight.By sharing ROTI maps from Indonesia and integrating them with regional GNSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionospheric research.
文摘BACKGROUND Monkeypox(Mpox),is a disease of global public health concern,as it does not affect only countries in western and central Africa.AIM To assess Burundi healthcare workers(HCWs)s’level of knowledge and confidence in the diagnosis and management of Mpox.METHODS We conducted a cross-sectional study via an online survey designed mainly from the World Health Organization course distributed among Burundi HCWs from June-July 2023.The questionnaire comprises 8 socioprofessional-related questions,22 questions about Mpox disease knowledge,and 3 questions to assess confidence in Mpox diagnosis and management.The data were analyzed via SPSS software version 25.0.A P value<0.05 was considered to indicate statistical significance.RESULTS The study sample comprised 471 HCWs who were mainly medical doctors(63.9%)and nurses(30.1%).None of the 22 questions concerning Mpox knowledge had at least 50%correct responses.A very low number of HCWs(17.4%)knew that Mpox has a vaccine.The confidence level to diagnose(21.20%),treat(18.00%)or prevent(23.30%)Mpox was low among HCWs.The confidence level in the diagnosis of Mpox was associated with the HCWs’age(P value=0.009),sex(P value<0.001),work experience(P value=0.002),and residence(P value<0.001).The confidence level to treat Mpox was significantly associated with the HCWs’age(P value=0.050),sex(P value<0.001),education(P value=0.033)and occupation(P value=0.005).The confidence level to prevent Mpox was associated with the HCWs’education(P value<0.001),work experience(P value=0.002),residence(P value<0.001)and type of work institution(P value=0.003).CONCLUSION This study revealed that HCWs have the lowest level of knowledge regarding Mpox and a lack of confidence in the ability to diagnose,treat or prevent it.There is an urgent need to organize continuing medical education programs on Mpox epidemiology and preparedness for Burundi HCWs.We encourage future researchers to assess potential hesitancy toward Mpox vaccination and its associated factors.
文摘This study was conducted at Fafan Research Center, Golajo research site to evaluate the effect of Moringa stenopetala and pigeon pea leaf supplementation on growth performance of short-eared Somali goat breed. A total of fifteen yearling indigenous short-eared Somali goat breeds with an initial weight of 15.2 ± 0.30 kg were assigned to three treatment groups using completely randomized design. Pigeon pea (Pp) and Moringa stenopetala (MS) feeds were formulated using 0%, 5%, and 10% inclusion levels of MSLM and PPLM as experimental diets, respectively. The feed of the experiment was prepared in two levels (2 kg of Moringa stenopetala and 2 kg of pigeon pea) and was supplemented to experimental animals in treatments one and two, respectively. The average e initial body weight of selected male goats was 18.82 ± 0.37, 18.8 ± 0.37 and 17.8 ± 0.37 kg under treatment groups T1, T2 and control respectively. Data was analyzed using general linear model (GLM) procedure of SAS computer package Version 9.0 (SAS, 2002). The final weights gain (FWG) of goats on T1 and T2 of experimental group was significantly (P 0.05) the final weight gain of goat supplemented on Moringa stenopetala (T1) and pigeon pea levels (T2). The mean average weight gains (AWG) obtained from the supplemented group in this study were 7.50 ± 0.37 and 7.82 ± 0.37 kg for T1 and T2, whereas mean weight gains for un-supplemented goats were found to be 6.26 ± 0.37 kg. Feeding of dried Moringa stenopetala and pigeon pea leaves mixture improved body weights and average daily body weight gain without affecting feed intake and overall health of Somali goat breed. As Moringa stenopetala and pigeon pea leaves are rich nitrogen/protein source, they can be used effectively as substitute for conventional concentrate in the diet of growing goats at small holder farmer’s level where they can be grown in abundance. Therefore, for higher quality of forage and higher total DM yield for animal feeding, moringa should be harvested at wider harvesting intervals of at least 6th- to 8th-week intervals. Similarly, for pigeon peas, 4- to 6-week harvesting interval can result in optimum forage as well as feed quality and resulted in better growth performances for Somali short-eared goat breeds.
文摘Muscle deconditioning due to hospitalisation is problematic, causing delayed discharges, more nursing, carer, or social service support following discharge, and possible discharge to a care home rather than the patient’s own home. Muscle deconditioning is associated with increased mortality, infections, depression, and reductions in patient mobility and ability to engage in their activities of daily living. Preserving muscle strength and function should form part of patients’ rehabilitation plans. Progressive resistance training (PRE) offers the most cost-effective way of preserving muscle strength and function;however, it is not routinely carried out in hospitals. A leg strengthening device (the S-Press) has been developed with the aim of improving access to effective PRE for adults. Using a qualitative approach, thematic analysis of interviews with physiotherapists, patients, and relative carers about their experience of using the S-Press provided insight into integrating PRE into patients’ rehabilitation, what promoted or prevented its use, and the outcomes associated with its use. Four overall themes emerged from the data. “Experience of Users” described that the S-Press was accessible, convenient, time efficient, portable, and manoeuvrable, and it provided an objective measure of progress. “Facilitators” included findings around how the S-Press was easy to use, motivational, and comfortable when in use. “Barriers” comprised the inability of some patients to use the S-Press independently and the identification of obstacles that prevented consistent use. “Impact and Benefits” represented the perceptions of increased leg strength and psychological benefits. The S-Press is beneficial for patients’ rehabilitation by offering PRE that is simple and easy to use, acceptable to both patients and professionals, and can be integrated as part of patients’ rehabilitation plans.
文摘Fever is the primary reason for consultation and admission to pediatric emergency departments. The aim of this study was to describe the clinical, etiological and prognostic aspects of acute fever in children aged 0 - 15 years. Patients and Methods: This was a prospective cross-sectional study from April 1, 2021 to March 31, 2022 and affected all children aged 0 to 15 years old with a temperature of 39˚C or higher (≥), having less than five days and hospitalized in the pediatric department of the Gabriel Touré University Hospital. Results: During the study period, 150 children were included, the sex-ratio was 0.85. Children aged 0 - 5 years represented 71.4% of the sample. References represented more than half of the sample, or 58% of cases. Body temperature was above 40˚C in 18.7% of cases. Functional signs were dominated by respiratory signs in 28% and digestive signs in 18%. Clinical pallor was found in 55.3% of children associated with signs of respiratory struggle in 70% of cases and tachycardia in 40% of patients. Anemia was present in 65.3% of patients. Hyperleucocytosis and leukopenia were found in 45.3% and 43.3% of patients respectively. The C-reactive protein was positive in 44.7% of patients and Cytobacteriological Examination and Chemistry of Cerebrospinal Fluid was positive in 8.7% of cases. The thick drop was positive in 44.7% of patients and blood cultures grew in 6 patients. Etiology was dominated by severe malaria 54 cases (36%), pneumonia (19.3%), meningitis (12.6%), and in those under one month it was bacterial neonatal infection (8.6%). In our study, slightly more than one patient out of three died during hospitalization, 36% (54 cases/150) and among these 70% (38 cases/54) were under 5 years old. The most lethal pathologies were severe malaria (36%), bacterial pneumonia (19.3%), meningitis (12.6%), bacterial neonatal infections (8.6%) and measles complicated by pneumonia (5.3%). Mortality during hospitalization was 36% of deaths (54 out of 150 patients) and 70.3% (38/54) of the deceased patients were under 5 years old. Conclusion: This study shows that fever is a frequent symptom and a sign of serious and very lethal pathologies. The cause of fever can be a diagnostic challenge for health workers. However, early identification of children at risk for serious illness could allow for prompt and appropriate management in appropriate settings.
文摘BACKGROUND Although breast milk is ideal for newborns,in some cases,it is replaced with cow’s milk,which contains proteins that increase the risk of cow’s milk protein allergy(CMPA).AIM To evaluate CMPA prevalence in Bahrain and compare clinical characteristics of children with immunoglobulin E(IgE)-and non-IgE-mediated CMPA.METHODS This retrospective cohort study examined children with CMPA diagnosed at the pediatric gastroenterology outpatient clinic of the Salmaniya Medical Complex,Bahrain,between 2014 and 2022,and assessed CMPA prevalence.Clinical presentations,laboratory findings,dietary modifications,and outcomes were compared between children with IgE-mediated and non-IgE-mediated CMPA.Categorical variables were compared using Fisher’s exact test or Pearson’sχ2 test,whereas continuous variables were compared using Student’s t-test or the Mann-Whitney U test.RESULTS Of 8332 patients,6022(72.3%)adhered to their appointment.Of them,618(10.3%)were suggested of having CMPA and 595(96.3%)were included;CMPA prevalence was 2%.Most patients were Bahraini(93.8%)and males(55.3%).Non-IgE-mediated type accounted for 77.3%cases and IgE-mediated type,22.7%.IgE-mediated CMPA presented more in boys(P=0.030),and later in life(5.1 months±4.5 months vs 4.2 months±4.2 months,P=0.016,95%CI:0.08-1.73),had more associated diseases(P<0.001);and presented with more cutaneous(P=0.024)and respiratory(P=0.003)manifestations,severe symptoms[rash/dry skin(P=0.031),facial swelling/angioedema(P=0.003),failure to thrive(P=0.013),apparent life-threatening event(P<0.001)],and positive physical findings(P=0.002)than non-IgE-mediated CMPA.Most patients were exclusively fed cow milk formula(50.3%).The amino acid-based formula(AAF)was most prescribed(60.5%)with no difference between the two types(P=0.173).Although breastfeeding was recommended to 49.6%,only 8.2%were exclusively breastfed.IgE-mediated CMPA was associated with a longer follow-up duration than non-IgE-mediated CMPA(17.3 months±14.0 months vs 13.5 months±13.4 months,P=0.005,95%CI:1.1-6.3).CONCLUSION This study revealed a high CMPA prevalence with clinical differences between both types that can influence treatment.AAF was most prescribed,while breastfeeding with dietary modification is rarely applied.
文摘Over the last few decades, dengue fever epidemics have increased in frequency and intensity worldwide, making it a major global concern for public health. Its prevention, which is essentially vector-based control, is already being compromised by reports of resistance of the main vector Aedes aegypti to insecticides. To tackle the rapid increase in insecticide resistance and outbreaks, the biological vector control is a promising approach. One of the strategies of this approach is the use of entomopathogenic fungi because of their great efficacy and their eco-friendly aspects. However, some aspects of their use, such as the low efficiency, the high cost of production and the sensitivity to various adverse conditions, need to be addressed for their successful large-scale application. Therefore, innovative technologies based on strains of transgenic fungi with improved biocontrol potentials by genetic engineering are actively pursued. Although these modified mycoinsecticides are acclaimed for their better effectiveness against target insects, the main concern remains their potential adverse effects on the environment and human health. The present review is dedicated to giving an update on recent developments in transgenic entomopathogenic fungi (TEF) for Aedes mosquito control. Future perspectives are also proposed to address the safety concerns related to the release of transgenic entomopathogenic fungi into the environment.
文摘Pancreatic cancer is usually associated with a poor prognosis.Surgery is the main curative treatment but pancreatic operations are aggressive and new tools that help clinicians to predict surgical and prognostic outcomes are necessary.Lu et al recently published a retrospective,single centre cohort study evaluating the impact of seven nutritional and inflammatory markers in pancreatic cancer surgical patients:The albumin-to-globulin ratio,prognostic nutritional index(PNI),systemic immune-inflammation index(SII),neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),nutritional risk index,and the geriatric nutritional risk index.A significant correlation was found between the PNI,SII,NLR,and PLR and a hospital discharge of less than 15 days.In a univariable analysis,PNI,SII,NLR and PLR were significantly related to recurrence-free survival and,in a multivariable analysis PNI was associated with overall survival.Various meta-analyses corroborate the results in terms of prognosis but individual studies are discordant on their usefulness.Besides,the cut-off values for these markers vary significantly between studies and there are no clinical trials comparing them to identify the most relevant ones.These are limitations when implementing nutritional and inflammatory biomarkers into clinical practice and further studies are needed in order to answer these questions.
文摘Introduction: The WHO’s measles control strategy is based on epidemiological surveillance and vaccination. Little is currently known about the performance of the surveillance system, particularly in outlying areas. It is in this context that the present study was carried out to evaluate the measles epidemiological surveillance system in the Kangaba health district. Method: This was a descriptive cross-sectional study with retrospective data collection for the period from 1 January to 31 December 2022 in the Kangaba health district with 18 epidemiological surveillance officers. Data were collected using an observation grid and documentary analysis. Results: We found a simplicity of 97%, a representativeness of 95% and a reactivity of 53%. Not all notified cases were sampled (64%). Of the 17 CSCom, 8 were positive. A total of 34 confirmed cases of measles were recorded, with one death. Conclusion: Overall, the system is functional and well-established in the health centres, but it remains important to ensure that suspected cases are investigated and that the time between sampling and the availability of laboratory results is respected.
文摘Chronic kidney disease(CKD),which represents a significant global health concern,is characterized by a gradual decline in kidney function,leading to complications such as electrolyte imbalance,cardiovascular disease,and immune dysfunction.Standard CKD management includes dietary modifications,ketoana-logues supplementation,blood pressure and blood glucose control,hydration maintenance,and treatment of the underlying causes.Emerging evidence has indicated a significant role of the gut microbiota in CKD,and that dysbiosis of the gut microbiota contributes to the progression of CKD towards end-stage renal disease.Probiotics and prebiotics have recently garnered attention owing to their potential to enhance gastrointestinal health and well-being by restoring the balance of the gut microbiota.Specific probiotic strains,including Lactobacillus and Bifidobacterium,promote beneficial bacterial growth,suppress harmful bacteria,and exert anti-inflammatory,antihypertensive,and antidiabetic effects.The combination of Streptococcus thermophilus,Lactobacillus acidophilus,Bifidobacterium longum,and Bacillus coagulans has demonstrated potential as a therapeutic formulation for CKD management in various studies,highlighting its promise in treating CKD;however,supporting evidence remains limited,making it crucial to conduct further investigations to determine the specific effects of different probiotic formulations on outcomes in patients with CKD.
文摘The integration of digital tools and effective knowledge management practices is critical for enhancing administrative efficiency and institutional continuity in higher education. This study investigates the relationships between knowledge modeling, institutional memory, leadership styles, technology, and administrative efficiency at the University of Cape Coast (UCC). The study sought to identify the challenges and opportunities in integrating digital tools into administrative processes and to provide actionable recommendations for improvement. A mixed-methods research design was employed, combining quantitative analysis using Partial Least Squares Structural Equation Modeling (PLS-SEM) with qualitative thematic analysis of interviews. The findings revealed key challenges, including resistance to change, fragmented knowledge repositories, and inadequate funding, alongside opportunities such as centralized knowledge systems, cost-effective open-source tools, and capacity-building initiatives. The study highlights the importance of strategic leadership, robust policies, and investments in digital infrastructure to enhance administrative practices. Policy implications include the need for clear digital transformation guidelines and leadership training to foster innovation and collaboration. Recommendations include investing in scalable digital tools, implementing comprehensive capacity-building programs, and promoting stakeholder engagement to drive successful digital integration. These insights provide a roadmap for UCC and similar institutions seeking to optimize administrative efficiency through digital transformation.
文摘The year 2025 marks the 75th anniversary of the establishment of diplomatic relations between China and Vietnam and the China-Vietnam People-to-People Exchange Year.Over the last 75 years,China has always regarded Vietnam as a priority in its neighborhood diplomacy,and Vietnam has regarded its relations with China as the top priority in its independent,all-round,and diversified foreign policy.The two sides have continuously strengthened mutually beneficial cooperation in various fields and elevated their comprehensive strategic partnership to new heights to build a China-Vietnam community with a shared future with strategic significance.
