Objective To study the contribution of executive function to abnormal recognition of facia expressions of emotion in schizophrenia patients. Methods Abnormal recognition of facial expressions of emotion was assayed ac...Objective To study the contribution of executive function to abnormal recognition of facia expressions of emotion in schizophrenia patients. Methods Abnormal recognition of facial expressions of emotion was assayed according to Japanese and Caucasian facial expressions of emotion （JACFEE）, Wisconsin card sorting test {WCST）, positive and negative symptom scale, and Hamilton anxiety and depression scale, respectively, in 88 paranoid schizophrenia patients and 75 healthy volunteers. Results Patients scored higher on the Positive and Negative Symptom Scale and the Hamilton Anxiety and Depression Scales, displayed lower JACFEE recognition accuracies and poorer WCST performances. The JACFEE recognition accuracy of contempt and disgust was negatively correlated with the negative symptom scale score while the recognition accuracy of fear was positively with the positive symptom scale score and the recognition accuracy of surprise was negatively with the general psychopathology score in patients. Moreover, the WCST could predict the JACFEE recognition accuracy of contempt, disgust, and sadness in patients, and the perseverative errors negatively predicted the recognition accuracy of sadness in healthy volunteers. The JACFEE recognition accuracy of sadness could predict the WCST categories in paranoid schizophrenia patients. Conclusion Recognition accuracy of social-/moral emotions, such as contempt, disgust and sadness is related to the executive function in paranoid schizophrenia patients, especially when regarding sadness.展开更多
Personality disorders often act as a common denominator for many psychiatric problems,and studies on personality disorders contribute to the etiopathology,diagnosis,and treatment of many mental disorders.In recent yea...Personality disorders often act as a common denominator for many psychiatric problems,and studies on personality disorders contribute to the etiopathology,diagnosis,and treatment of many mental disorders.In recent years,increasing evidence from various studies has shown distinctive features of personality disorders,and that from genetic and neuroimaging studies has been especially valuable.Genetic studies primarily target the genes encoding neurotransmitters and enzymes in the serotoninergic and dopaminergic systems,and neuroimaging studies mainly focus on the frontal and temporal lobes as well as the limbic-paralimbic system in patients with personality disorders.Although some studies have suffered due to unclear diagnoses of personality disorders and some have included few patients for a given personality disorder,great opportunities remain for investigators to launch new ideas and technologies in the field.展开更多
Objective When English-speaking people listen to the Deutsch ＂high-low＂ word illusion, they report hearing English words. Whether Chinese-speaking people report Chinese words when listening to the illusion, or wheth...Objective When English-speaking people listen to the Deutsch ＂high-low＂ word illusion, they report hearing English words. Whether Chinese-speaking people report Chinese words when listening to the illusion, or whether any reported words might be correlated with personality traits as previous investigations have demonstrated for listening to music in other cultures, is open to question. The present study aimed to address this. Methods A total of 308 right-handed, healthy volunteers （177 women and 131 men） were given the illusion test and asked to answer the Zuckerman-Kuhlman personality questionnaire （ZKPQ）. Their depressive tendency was measured by the Plutchik-van Praag depression inventory （PVP）. Results There was no gender effect regarding either the PVP score or the number of reported Chinese words from the illusion. Women scored higher on ZKPQ neuroticism-anxiety than men. The number of meaningful Chinese words reported was correlated with the ZKPQ impulsive sensation-seeking, aggression-hostility, and activity scores. Some words reported by participants who scored higher on these three traits were related in meaning to those scales. Conclusion Our preliminary results suggest that when Chinese-speaking people listen to the Deutsch ＂high-low＂ word illusion, they might use personality-related, specific cognitive schemata.展开更多
基金supported by the Natural Science Foundation of China (Nos. 30971042 and 91132715)the Innovative Research Team for Translational Neuropsychiatric Medicine, Zhejiang Province (2011R50049)the Program for Changjiang Scholars and Innovative Research Team in University, Chinese Ministry of Education (No. IRT1038)
文摘Objective To study the contribution of executive function to abnormal recognition of facia expressions of emotion in schizophrenia patients. Methods Abnormal recognition of facial expressions of emotion was assayed according to Japanese and Caucasian facial expressions of emotion （JACFEE）, Wisconsin card sorting test {WCST）, positive and negative symptom scale, and Hamilton anxiety and depression scale, respectively, in 88 paranoid schizophrenia patients and 75 healthy volunteers. Results Patients scored higher on the Positive and Negative Symptom Scale and the Hamilton Anxiety and Depression Scales, displayed lower JACFEE recognition accuracies and poorer WCST performances. The JACFEE recognition accuracy of contempt and disgust was negatively correlated with the negative symptom scale score while the recognition accuracy of fear was positively with the positive symptom scale score and the recognition accuracy of surprise was negatively with the general psychopathology score in patients. Moreover, the WCST could predict the JACFEE recognition accuracy of contempt, disgust, and sadness in patients, and the perseverative errors negatively predicted the recognition accuracy of sadness in healthy volunteers. The JACFEE recognition accuracy of sadness could predict the WCST categories in paranoid schizophrenia patients. Conclusion Recognition accuracy of social-/moral emotions, such as contempt, disgust and sadness is related to the executive function in paranoid schizophrenia patients, especially when regarding sadness.
基金supported by a grant from the Natural Science Foundation of China (91132715)
文摘Personality disorders often act as a common denominator for many psychiatric problems,and studies on personality disorders contribute to the etiopathology,diagnosis,and treatment of many mental disorders.In recent years,increasing evidence from various studies has shown distinctive features of personality disorders,and that from genetic and neuroimaging studies has been especially valuable.Genetic studies primarily target the genes encoding neurotransmitters and enzymes in the serotoninergic and dopaminergic systems,and neuroimaging studies mainly focus on the frontal and temporal lobes as well as the limbic-paralimbic system in patients with personality disorders.Although some studies have suffered due to unclear diagnoses of personality disorders and some have included few patients for a given personality disorder,great opportunities remain for investigators to launch new ideas and technologies in the field.
基金supported by grants from the National Natural Science Foundation of China (30971042)the Innovative Research Team for Translational Neuropsychiatric Medicine, Zhejiang Province (2011R50049)the Program for Changjiang Scholars and Innovative Research Team in University,Chinese Ministry of Education (IRT1038)
文摘Objective When English-speaking people listen to the Deutsch ＂high-low＂ word illusion, they report hearing English words. Whether Chinese-speaking people report Chinese words when listening to the illusion, or whether any reported words might be correlated with personality traits as previous investigations have demonstrated for listening to music in other cultures, is open to question. The present study aimed to address this. Methods A total of 308 right-handed, healthy volunteers （177 women and 131 men） were given the illusion test and asked to answer the Zuckerman-Kuhlman personality questionnaire （ZKPQ）. Their depressive tendency was measured by the Plutchik-van Praag depression inventory （PVP）. Results There was no gender effect regarding either the PVP score or the number of reported Chinese words from the illusion. Women scored higher on ZKPQ neuroticism-anxiety than men. The number of meaningful Chinese words reported was correlated with the ZKPQ impulsive sensation-seeking, aggression-hostility, and activity scores. Some words reported by participants who scored higher on these three traits were related in meaning to those scales. Conclusion Our preliminary results suggest that when Chinese-speaking people listen to the Deutsch ＂high-low＂ word illusion, they might use personality-related, specific cognitive schemata.
