目的:旨在研究风湿免疫病患者不同年龄组间血清免疫球蛋白(IgG, IgA, IgM)的含量特点。方法:选取2023年1月至2023年12月就诊于泰安中心医院风湿免疫科门诊及住院患者的病历资料共13,949例。统计其IgM、IgG、IgA值进行相关性分析,结果:对...目的:旨在研究风湿免疫病患者不同年龄组间血清免疫球蛋白(IgG, IgA, IgM)的含量特点。方法:选取2023年1月至2023年12月就诊于泰安中心医院风湿免疫科门诊及住院患者的病历资料共13,949例。统计其IgM、IgG、IgA值进行相关性分析,结果:对于IgG,三个年龄组的平均值分别为9.406、12.211、12.436,表明IgG水平随年龄增长呈上升趋势(F = 735.069, P 60岁组及31~60岁组显著高于1~30岁组,分别为2.751、2.69和1.205 (F = 1097.913, P Objective: To investigate the content of immunoglobulin (IgG, IgA, IgM) in serum of patients with rheumatic immune diseases in different age groups and between adult men and women. Methods: A total of 13,949 outpatients and inpatients in the Department of Rheumatology and Immunology of Tai’an Central Hospital, Qingdao University from January 2023 to December 2023 were enrolled. Results: For IgG, the mean values of the three age groups were 9.406, 12.211 and 12.436, respectively, indicating that the IgG level showed an upward trend with age (F = 735.069, P the 60-year-old group and the 31~60 years old group was significantly higher than that in the 1~30 years old group, which were 2.751, 2.69 and 1.205 (F = 1097.913, P < 0.001), respectively, and the level of IgA increased with aging. Conclusion: There is a certain relationship between immunoglobulin level and age in patients with rheumatic immune diseases.展开更多
目的系统评价高敏C反应蛋白(hs-CRP)与患者行冠状动脉造影(CAG)或经皮冠状动脉介入治疗(PCI)术后发生对比剂肾病(CIN)的相关性。方法检索PubMed、Web of Science、中国生物医学文献数据库、中国知网、万方数据等数据库,选取从建库到2021...目的系统评价高敏C反应蛋白(hs-CRP)与患者行冠状动脉造影(CAG)或经皮冠状动脉介入治疗(PCI)术后发生对比剂肾病(CIN)的相关性。方法检索PubMed、Web of Science、中国生物医学文献数据库、中国知网、万方数据等数据库,选取从建库到2021年3月7日发表的CIN组和非CIN组CAG或PCI患者术前hs-CRP水平的研究。获得相关数据后,使用RevMan 5.3和Stata 12.0软件进行Meta分析。结果最终纳入了14项相关研究,包括11885例CAG或PCI治疗患者(1034例CIN患者和10851例非CIN患者)。Meta分析结果显示,CIN组hs-CRP水平显著高于非CIN组(WMD=3.77,95%CI:2.80~4.74,P<0.001,I2=93%),CAG或PCI术前hs-CRP水平较高的患者更容易发生CIN。敏感性分析表明该研究的结果具有较好的稳定性,亚组分析的结果表明样本量、研究人群、地理位置和CIN的定义的差异具有统计学意义。结论现有证据显示,高hs-CRP水平是CAG或PCI术后CIN的危险因素,然而仍需要大样本试验来支持这一结论。展开更多
文摘目的:旨在研究风湿免疫病患者不同年龄组间血清免疫球蛋白(IgG, IgA, IgM)的含量特点。方法:选取2023年1月至2023年12月就诊于泰安中心医院风湿免疫科门诊及住院患者的病历资料共13,949例。统计其IgM、IgG、IgA值进行相关性分析,结果:对于IgG,三个年龄组的平均值分别为9.406、12.211、12.436,表明IgG水平随年龄增长呈上升趋势(F = 735.069, P 60岁组及31~60岁组显著高于1~30岁组,分别为2.751、2.69和1.205 (F = 1097.913, P Objective: To investigate the content of immunoglobulin (IgG, IgA, IgM) in serum of patients with rheumatic immune diseases in different age groups and between adult men and women. Methods: A total of 13,949 outpatients and inpatients in the Department of Rheumatology and Immunology of Tai’an Central Hospital, Qingdao University from January 2023 to December 2023 were enrolled. Results: For IgG, the mean values of the three age groups were 9.406, 12.211 and 12.436, respectively, indicating that the IgG level showed an upward trend with age (F = 735.069, P the 60-year-old group and the 31~60 years old group was significantly higher than that in the 1~30 years old group, which were 2.751, 2.69 and 1.205 (F = 1097.913, P < 0.001), respectively, and the level of IgA increased with aging. Conclusion: There is a certain relationship between immunoglobulin level and age in patients with rheumatic immune diseases.
文摘目的系统评价高敏C反应蛋白(hs-CRP)与患者行冠状动脉造影(CAG)或经皮冠状动脉介入治疗(PCI)术后发生对比剂肾病(CIN)的相关性。方法检索PubMed、Web of Science、中国生物医学文献数据库、中国知网、万方数据等数据库,选取从建库到2021年3月7日发表的CIN组和非CIN组CAG或PCI患者术前hs-CRP水平的研究。获得相关数据后,使用RevMan 5.3和Stata 12.0软件进行Meta分析。结果最终纳入了14项相关研究,包括11885例CAG或PCI治疗患者(1034例CIN患者和10851例非CIN患者)。Meta分析结果显示,CIN组hs-CRP水平显著高于非CIN组(WMD=3.77,95%CI:2.80~4.74,P<0.001,I2=93%),CAG或PCI术前hs-CRP水平较高的患者更容易发生CIN。敏感性分析表明该研究的结果具有较好的稳定性,亚组分析的结果表明样本量、研究人群、地理位置和CIN的定义的差异具有统计学意义。结论现有证据显示,高hs-CRP水平是CAG或PCI术后CIN的危险因素,然而仍需要大样本试验来支持这一结论。
