卵黄囊瘤(Yolk Sac Tumor, YST),又称为内胚窦瘤(Endodermal Sinus Tumor, EST),是一种罕见的来源于原始生殖细胞的恶性肿瘤(Germ Cell Tumor, GCT),归为非精原细胞瘤的一种。由于其分化程度低,增殖速度快,故在生殖细胞恶性肿瘤中恶性...卵黄囊瘤(Yolk Sac Tumor, YST),又称为内胚窦瘤(Endodermal Sinus Tumor, EST),是一种罕见的来源于原始生殖细胞的恶性肿瘤(Germ Cell Tumor, GCT),归为非精原细胞瘤的一种。由于其分化程度低,增殖速度快,故在生殖细胞恶性肿瘤中恶性程度很高,预后差。本文通过回顾收治的1例纵膈卵黄囊瘤伴双肺多发转移的青年男性患者经标准方案化疗后仍迅速进展至死亡的诊治过程,为纵膈卵黄囊瘤肺转移的临床诊疗工作提供一些经验及思路。Yolk Sac Tumor (YST), also known as Endodermal Sinus Tumor (EST), is a rare malignant tumor derived from primitive Germ Cell Tumor (GCT), which is classified as a type of non-seminoma. Due to its low degree of differentiation and rapid proliferation, it has a high degree of malignancy and a poor prognosis in germ cell malignancies. This article reviews the diagnosis and treatment process of a young male patient with mediastinal yolk sac tumor with multiple metastases in both lungs who died rapidly after standard chemotherapy, so as to provide some experience and ideas for the clinical diagnosis and treatment of lung metastasis of mediastinal yolk sac tumor.展开更多
文摘卵黄囊瘤(Yolk Sac Tumor, YST),又称为内胚窦瘤(Endodermal Sinus Tumor, EST),是一种罕见的来源于原始生殖细胞的恶性肿瘤(Germ Cell Tumor, GCT),归为非精原细胞瘤的一种。由于其分化程度低,增殖速度快,故在生殖细胞恶性肿瘤中恶性程度很高,预后差。本文通过回顾收治的1例纵膈卵黄囊瘤伴双肺多发转移的青年男性患者经标准方案化疗后仍迅速进展至死亡的诊治过程,为纵膈卵黄囊瘤肺转移的临床诊疗工作提供一些经验及思路。Yolk Sac Tumor (YST), also known as Endodermal Sinus Tumor (EST), is a rare malignant tumor derived from primitive Germ Cell Tumor (GCT), which is classified as a type of non-seminoma. Due to its low degree of differentiation and rapid proliferation, it has a high degree of malignancy and a poor prognosis in germ cell malignancies. This article reviews the diagnosis and treatment process of a young male patient with mediastinal yolk sac tumor with multiple metastases in both lungs who died rapidly after standard chemotherapy, so as to provide some experience and ideas for the clinical diagnosis and treatment of lung metastasis of mediastinal yolk sac tumor.
