Background: Chemotherapy induced mucositis is one of the deterring factors influencing adherence to cancer treatment. Sodium bicarbonate mouth wash was recently shown to increase patients’ compliance. However, the co...Background: Chemotherapy induced mucositis is one of the deterring factors influencing adherence to cancer treatment. Sodium bicarbonate mouth wash was recently shown to increase patients’ compliance. However, the cost implication of this strategy was never explored. Aim: This study is designed to explore the compounding of sodium bicarbonate 2% mouth wash from sodium bicarbonate powder USP and commercially procured intravenous solution, and to determine the estimated cost implication for patients using this strategy. Materials and Methods: Sodium bicarbonate 2% were compounded using commercially procured sterile intravenous 8.4% solution and powder USP, diluted and dissolved in sterile water for irrigation respectively. The estimated cost savings between the 2 methods were compared to each other as well as to savings from when used in preventing or in adjuvant therapy for chemotherapy induced mucositis. Ethical approval not required by UVA Institutional Review Board. Study conducted according to the International Standards of Good Practice. Result: We came up with a new recipe, sodium bicarbonate 2% mouth wash using commercially procured sterile liquid formulation. Due to shortage, we compounded with sodium bicarbonate powder USP. Using USP 795 regulation, we assigned 14 days beyond use date with refrigeration to these formulations. These formulations resulted in estimated cost savings of $3597.52 and $3686.56 respectively if patients were to be treated for chemotherapy induced mucositis for 21 days. When compared to commercially procured sterile liquid formulation, the use of powder USP, will lead to additional estimated 60 to 66.67% savings for patients. Conclusion: By using sodium bicarbonate powder or solution to compound a 2% mouth wash, we came up with a cheap product that could be used by patients in the moment in the hospital. We were also able to suggest ways that an estimated cost savings for patients undergoing cancer treatment that use this product can be computed.展开更多
The wash-out filter （WF） technique is used to control the flutter of a two dimensional airfoil with cubic non-linearity in incompressible flow. Firstly, Hopf bifurcation theory is used to determine the point at whic...The wash-out filter （WF） technique is used to control the flutter of a two dimensional airfoil with cubic non-linearity in incompressible flow. Firstly, Hopf bifurcation theory is used to determine the point at which the nonlinear controller is introduced. The system is then transformed into Jordan canonical form, based on analysis of linearized eigenvalues of the system. Secondly, for the introduced WF controller, the linear control gain is determined according to Hopf bifurcation condition. The sym- bolic computing program of normal form direct method （NFDM） is also used to obtain the normal form of the controlled system. The non-linear control gain can be determined based on the relation of the type of bifurcation and the parameters of the normal form, to transform sub-critical Hopf bifurcation to be su- per-critical one. Lastly, numerical simulations are used to certify the validity of theoretical analysis, in which the amplitude of flutter or limit cycle of the controlled system is reduced greatly, comparing to the original system.展开更多
Phytoremediation is a cheap and environmentally friendly technique in which green plants in situ are used to clean the soil, sediments and water of heavy metals. This study investigated the phytoremediation potential ...Phytoremediation is a cheap and environmentally friendly technique in which green plants in situ are used to clean the soil, sediments and water of heavy metals. This study investigated the phytoremediation potential of six naturally occurring macrophytes from Nange (a stream in Buea municipality where cars have been driven into and washed for over 20 years). Plant samples were collected before and after car wash, then analysed for copper, zinc, lead and cadmium accumulation. There was an increase in concentration of all the four heavy metals in water after carwash point, with Zn having the highest concentration (0.27 mg/L). Mean concentration of the heavy metals in the water showed that Zn and Pb had the highest concentrations (0.24 mg/L each) while the least concentration was obtained in Cu (0.12 mg/kg). Heavy metal concentrations in the sediments were higher after car wash point than before. Cadmium had the highest concentration (5.58 mg/kg) while Cu had the least (0.75 mg/kg). <em>Ludwigia peruviana</em> had the highest BAFs for all the heavy metals (22.95 for Cu, 33.41 for Zn, 21.79 for Pb and 7.85 for Cd). Species with the leasts were: <em>Anubias barteri</em> for Cu (7.16), <em>Polygonum persicaria</em> for Zn (14.28), <em>Rorippa nasturtium-aquaticum</em> for Pb (11.60) and <em>Vallisneria spiralis</em> for Cd (1.98). <em>L. peruviana</em> had the highest BAC values (Cu = 10.11, Zn = 14.73, Pb = 11.39, Cd = 3.85) and BCF values (Cu = 12.84, Zn = 18.67, Pb = 10.40, Cd = 4.00). <em>A. barteri</em> had the highest TF (Cu = 1.49, Zn = 1.27, Cd = 1.99) except for Pb where both <em>A. barteri </em>and <em>L. peruviana</em> each had a TF of 1.10. While all the six plants were found to be good accumulators of the heavy metals, <em>L. peruviana</em> showed remarkable efficiency indicating that the species is a good candidate for cleaning such environments.展开更多
Garment washing is a significant area of the apparel industry. Washing is vital for denim and other casual garments for bringing some interesting washed-down effects. Unwashed condition does not exhibit customer’s de...Garment washing is a significant area of the apparel industry. Washing is vital for denim and other casual garments for bringing some interesting washed-down effects. Unwashed condition does not exhibit customer’s desired look, but after washing, the same garment becomes prominent in improved appearance, softness, comfort, light and dark shade, and patchy look that creates customer’s absolute satisfaction. Garment washing process increases the appeal with a lucrative outlook brought about by mechanical or chemical treatments in dry or wet conditions. This study gives an indication of different types of washing processes and the change of physical and chemical properties due to application of wet and dry washing processes as an imparting desired effect on garments. The aim of the project is to find out the changes that occur in physical properties of denim when it is subjected to stone enzyme wash on 12-ounce, 10-ounce and 8-ounce denim pants. Three different shades, namely dark shade, medium shade and light wash, were taken into consideration. Different behaviors and properties of the garments were found in the physical properties of the samples.展开更多
Greenwashing behaviors(GWBs)in green finance products(GFPs)by enterprises seriously hinder the realization of environmental protection goals.However,methods for effectively regulating GWBs in GFPs are unclear.This stu...Greenwashing behaviors(GWBs)in green finance products(GFPs)by enterprises seriously hinder the realization of environmental protection goals.However,methods for effectively regulating GWBs in GFPs are unclear.This study constructed a tripartite evolutionary game model to analyze the formation and governance mechanisms of GWBs in GFPs among regulatory authorities,enterprises,and investors.Subsequently,the stability equilibrium strategy and key factors influencing the system equilibrium were discussed.Several interesting conclusions were drawn.First,we demonstrated that an interdependence mechanism exists among three game agents who mutually influence each other.The larger the probability of regulatory authorities choosing active supervision and investors adopting feedback,the more enterprises are willing to carry out green projects.Second,three corresponding governance modes for GWBs were put forward following the developmental stages of GFPs.Among these,the collaboration mode is the most effective in incentivizing enterprises to implement green projects.Third,based on sensitivity simulations,the initial willingness of the tripartite stakeholders,investor feedback cost,investor compensation,the penalty for greenwashing enterprises,and the reputational benefit of enterprises are critical factors that influence evolutionary results.Finally,targeted countermeasures were provided for regulatory authorities to prevent enterprises from engaging in GWBs.展开更多
Simulating the traditional painting art by computer graphics is a challenging and attractive subject. Basing on the experience in the ink wash drawing, in this paper, we expound the artistic characters of ink wash p...Simulating the traditional painting art by computer graphics is a challenging and attractive subject. Basing on the experience in the ink wash drawing, in this paper, we expound the artistic characters of ink wash painting and particularly analyze the characteristics of the materials used in the ink wash drawing and the relationships between them. A simulation model is presented and some typical visual effects of the ink wash painting are realized.展开更多
AIM： To establish a more sensitive method for detection of free cancer cells in peritoneal washes from gastric cancer patients during surgery and to evaluate its clinical significance. METHODS： The carcinoembryonic ...AIM： To establish a more sensitive method for detection of free cancer cells in peritoneal washes from gastric cancer patients during surgery and to evaluate its clinical significance. METHODS： The carcinoembryonic antigen （CEA） mRNA levels in peritoneal washes from 65 cases of gastric cancer were detected by real-time RT-PCR. Peritoneal lavage cytology （PLC） was applied simultaneously to detection of free cancer cells. Negative controls included peritoneal washes from 5 cases of benign gastric disease and blood samples from 5 adult healthy volunteers. RESULTS： There was no CEA mRNA in peritoneal washes from benign gastric disease patients and in blood of adult healthy volunteers. The positive percentage of free cancer cells detected by real-time RT-PCR was 47.7% and only 22.3% by PLC. The positive rate of CEA mRNA was significantly related with serosa invasion between peritoneal metastasis and stage of gastric cancer. CONCLUSION： Real-time RT-PCR is a sensitive and rapid method for the detection of free cancer cells in peritoneal washes. The presence of free cancer cells in peritoneal washes is related to the Pathologic stage of gastric cancer.展开更多
method of extracting astaxanthin from Phaffia rhodozyma with various solvents after acid washing was investigated. The extraction efficiency was distinctly increased after acid washing of P. rhodozyma cells. When the ...method of extracting astaxanthin from Phaffia rhodozyma with various solvents after acid washing was investigated. The extraction efficiency was distinctly increased after acid washing of P. rhodozyma cells. When the concentration of HCl was 0.4 mol.L^-1, the highest extraction efficiency of astaxanthin was achieved which was about three times higher than the control. Acetone or benzene as single polar or non-polar solvent was the most ef- fective solvent in our research. With a combination of isopropanol and n-hexane （volume ratio of 2 ： 1）, the maxi- mal extraction efficiency was achieved, approximately 60% higher than that obtained with a single solvent. The liquid-solid ratio and the extracting time were also optimized. Under the optimum extraction conditions, the extraction yield of astaxanthin exceeded 98%.展开更多
BACKGROUND The pathogenesis of gastroesophageal reflux disease(GERD)is closely associated with the intestinal bacteria composition and their metabolites.AIM To investigate whether washed microbiota transplantation(WMT...BACKGROUND The pathogenesis of gastroesophageal reflux disease(GERD)is closely associated with the intestinal bacteria composition and their metabolites.AIM To investigate whether washed microbiota transplantation(WMT)improves symptoms of nonerosive reflux disease(NERD)with proton pump inhibitor(PPI)dependency.METHODS Patients with recurrent NERD and PPI dependency at the First Affiliated Hospital of Guangdong Pharmaceutical University from 2017 to 2018 were included and divided into a WMT or PPI group treated with PPI with/without WMT.The endpoint was NERD symptom frequency evaluated 1 mo after WMT using reflux disease questionnaire(RDQ)and GERD questionnaire(GERDQ)scores,remission time,PPI dose,and the examination of intestinal mucosal barrier function.RESULTS In the WMT(n=15)and PPI(n=12)groups,the total remission rate at 1 mo after treatment was 93.3%vs 41.7%.Compared with the PPI group,the WMT group showed better results in GERDQ(P=0.004)and RDQ(P=0.003)and in remission months(8 vs 2,P=0.002).The PPI dose was reduced to some extent for 80%of patients in the WMT group and 33.3%in the PPI group.In 24 patients,intestinal mucosal barrier function was examined before treatment,and changes in the degree of damage were observed in 13 of these patients after treatment.Only one of the 15 patients had minor side effects,including a mushy stool two or three times a day,which resolved on their own after 1 wk.CONCLUSION This study is the first to demonstrate that WMT may be safe and effective for relieving NERD symptoms and reducing PPI dependency and recurrence.展开更多
Coal Washing Exploration in India dates back to 1900s; though, first coking coal washeries in India were installed after independence. At present, most of the coking coal washeries are owned by Public Sector Companies...Coal Washing Exploration in India dates back to 1900s; though, first coking coal washeries in India were installed after independence. At present, most of the coking coal washeries are owned by Public Sector Companies; whereas, most of the non-coking coal washeries are owned by Private Sector. Even after six decades of coal washing practices, there has not been significant development in the coal washing intelligentsia. Indian Coal Washing industry is still dependent on imported equipment, which has been designed to treat coal that is significantly different from Indian coal of drift origin. In this paper, authors have ventured into evolution of Indian Coal Washing Industry （with a focus on coking coal washing sector）, its present condition and future prospect for growth. The paper emphasizes need for developing indigenous solutions to industrial challenges and highlights importance of increased coordination among academia-research institutions and coal industry.展开更多
Production of glass-ceramics by sintering the molten slag obtained from electric arc furnace treatment of fly ash was investigated. The effect of washing pretreatment prior to melting the fly ash on the microstructure...Production of glass-ceramics by sintering the molten slag obtained from electric arc furnace treatment of fly ash was investigated. The effect of washing pretreatment prior to melting the fly ash on the microstructure and properties of the glass-ceramics was examined. The results show that washing pretreatment of fly ash can decrease alkali metal chloride and increase network former in fly ash, which results in the increase of peak crystallization temperature of parent glass and strengthening of properties of bending strength and chemical stability of the glass-ceramics. The optimal heat treatment temperature for parent glass of washed fly ash is 1 173 K, at which the crystalline phase of glass-ceramics is composed of gelignite （Ca2A12SiO7） and akermanite （Ca2MgSi207）. Glass-ceramics produced at optimal heat treatment temperature are excellent in term of the physical and chemical properties and leaching characteristics, indicating attractive potential as substitute of nature materials.展开更多
CO2 removal from biogas by water washing system was investigated with various parameters, including liquid/ gas ratio, pressure, temperature, and CO2 content. The results indicate that CO2 removal ratio could reach 34...CO2 removal from biogas by water washing system was investigated with various parameters, including liquid/ gas ratio, pressure, temperature, and CO2 content. The results indicate that CO2 removal ratio could reach 34.6%- 94.2% as liquid/gas ratio increased from 0.14 to 0.50. Increasing pressure （from 0.8 to 1.2 MPa） could improve gas purification with a constant inflow rate of gas. Temperature played a key role in the process and lower temper- ature in absorption tower was beneficial for reducing CO2 content. CO2 removal ratio could reach 24.4%-83.2% when CO2 content in the simulated gas was 25%-45%. The lowest CO2 content after absorption was 2.6% at 1.2 MPa with 400 L·h-1 gas flow and 200 L·h-1 water flow, which meets the requirement of CO2 content in natural Ras for vehicle fuel.展开更多
Different LiNi0.8Co0.15Al0.05O2 cathode materials were washed by ethanol solvent. Inductively coupled plasma atomic emission spectroscopy（ICP-AES）, Fourier transformed infrared（FTIR） spectrum, X-ray diffraction（...Different LiNi0.8Co0.15Al0.05O2 cathode materials were washed by ethanol solvent. Inductively coupled plasma atomic emission spectroscopy（ICP-AES）, Fourier transformed infrared（FTIR） spectrum, X-ray diffraction（XRD）, scanning electron microscopy（SEM）, charge-discharge test and electrochemical impedance spectroscopy（EIS） were used to evaluate the elemental contents, structures, morphologies and electrochemical properties of samples. The results show that ethanol washing can remove effectively the synthetic residues LiOH/Li2 O on the freshly-prepared LiNi0.8Co0.15Al0.05O2 and make the sample much more resistant to H2O and CO2, without destroying its bulk structure, surface morphology and electrochemical performances. Moreover, the discharge specific capacity and cycle performance of LiNi0.8Co0.15Al0.05O2 after storage in air with a relative humidity of 80% for three months are improved by immediate ethanol washing.展开更多
We conducted experimental and numerical studies on the vibrating modes of a dragon wash basin (DWB) and the free surface waves inside the DWB. Both the vibration of the DWB and the sound produced were studied carefull...We conducted experimental and numerical studies on the vibrating modes of a dragon wash basin (DWB) and the free surface waves inside the DWB. Both the vibration of the DWB and the sound produced were studied carefully. It was found that the DWB can be excited at different intrinsic modes under different excitation, including striking and rubbing it fast/slowly. However, with gentle rubbing, the DWB will be excited mainly at the first vibrating mode. We showed that the concave side wall of a DWB decreases the intrinsic frequencies (compared with a straight side wall), and the ears of a DWB lead to breaking of the vibrating-axisymmetry and cause the separation of modes I/II and IV/V as well. A theoretical model, in which the water is assumed to be incompressible and inviscid, is applied to the first order vibration and predicts the relation of vibrating frequency versus water depth in the system. The measurement shows that both the radial and azimuthal waves are produced as DWB is working. The frequency of the first component of the surface wave is twice as large as the second one induced by non-linear effects. For both the radial and azimuthal waves, the dispersion relation is presented in the framework of capillary wave theory.展开更多
Objective:Coronavirus disease 2019(COVTD-19)is often accompanied by gastrointestinal symptoms,which are related to gut microbiota dysbiosis(GMD).Whether washed microbiota transplantation(WMT)is an effective treatment ...Objective:Coronavirus disease 2019(COVTD-19)is often accompanied by gastrointestinal symptoms,which are related to gut microbiota dysbiosis(GMD).Whether washed microbiota transplantation(WMT)is an effective treatment for COV1D-19 patients suspected of having GMD by restoring the gut microbiota is unknown.This study is designed to explore the efficacy and safety of WMT in COVID-19 patients suspected of having GMD.Methods:This is a randomized,multicenter,single-blind prospective study.COVID-19 patients suspected of having GMD will be randomly divided to receive routine treatment only or to receive routine treatment and WMT.The frequency of WMT will be once a day for three consecutive days.Laboratory and imaging examinations will be performed at admission,1 and 2 weeks after treatment,and on the day of discharge.Then a telephone follow-up will be conducted at 1st week,2nd week,and 6th month after discharge.The clinical efficacy and safety of WMT in COVD-19 patients suspected of having GMD and the effects of WMT on the organ function,homeostasis,inflammatory response,intestinal mucosal barrier function,and immunity of the patients will be evaluated.Results:By following the proposed protocol,WMT is expected to be efficacious and safe for the treatment of COVID-19 patients suspected of having GMD,and the therapeutic effect is expected to be associated with improvement of the intestinal mucosal barrier function,inflammatory response,and immunity.Conclusion:The findings from this study may offer a new approach for the prevention and treatment of COVID-19 patients suspected of having GMD.展开更多
Water-washing removes fluoride from Antarctic krill but produces large volumes of wash water containing water-soluble proteins and fluoride. The freeze concentration method was tested to determine if it could be used ...Water-washing removes fluoride from Antarctic krill but produces large volumes of wash water containing water-soluble proteins and fluoride. The freeze concentration method was tested to determine if it could be used to recover water-soluble proteins while leaving the fluoride in solution. After freezing and thawing the wash water, protein and fluoride contents of the thawed fractions were determined to explore the melting regularity of components in the wash water. The highest concentration factors of protein and fluoride were obtained after 80 min of thawing, such as 1.48 ± 0.06 and 1.35 ± 0.04 times, respectively. The free amino-nitrogen(FAN) content and sodium dodecyl sulfate-polyacrylamide gel electrophoresis pattern results revealed that the highest concentrations of all ingredients were obtained after 80 min of the process. The degree of hydrolysis of all fractions from the thawing process fluctuated in a narrow range around 12% during the entire process, indicating that the thawing order did not change with various proteins or time during the entire thawing course. These results demonstrate that the freeze concentration method can be used to concentrate protein solutions, even those with fluoride. It was concluded that condensation was achieved and no ingredient could be separated, regardless of fluoride, amino acids, or different proteins in the water.展开更多
文摘Background: Chemotherapy induced mucositis is one of the deterring factors influencing adherence to cancer treatment. Sodium bicarbonate mouth wash was recently shown to increase patients’ compliance. However, the cost implication of this strategy was never explored. Aim: This study is designed to explore the compounding of sodium bicarbonate 2% mouth wash from sodium bicarbonate powder USP and commercially procured intravenous solution, and to determine the estimated cost implication for patients using this strategy. Materials and Methods: Sodium bicarbonate 2% were compounded using commercially procured sterile intravenous 8.4% solution and powder USP, diluted and dissolved in sterile water for irrigation respectively. The estimated cost savings between the 2 methods were compared to each other as well as to savings from when used in preventing or in adjuvant therapy for chemotherapy induced mucositis. Ethical approval not required by UVA Institutional Review Board. Study conducted according to the International Standards of Good Practice. Result: We came up with a new recipe, sodium bicarbonate 2% mouth wash using commercially procured sterile liquid formulation. Due to shortage, we compounded with sodium bicarbonate powder USP. Using USP 795 regulation, we assigned 14 days beyond use date with refrigeration to these formulations. These formulations resulted in estimated cost savings of $3597.52 and $3686.56 respectively if patients were to be treated for chemotherapy induced mucositis for 21 days. When compared to commercially procured sterile liquid formulation, the use of powder USP, will lead to additional estimated 60 to 66.67% savings for patients. Conclusion: By using sodium bicarbonate powder or solution to compound a 2% mouth wash, we came up with a cheap product that could be used by patients in the moment in the hospital. We were also able to suggest ways that an estimated cost savings for patients undergoing cancer treatment that use this product can be computed.
文摘The wash-out filter （WF） technique is used to control the flutter of a two dimensional airfoil with cubic non-linearity in incompressible flow. Firstly, Hopf bifurcation theory is used to determine the point at which the nonlinear controller is introduced. The system is then transformed into Jordan canonical form, based on analysis of linearized eigenvalues of the system. Secondly, for the introduced WF controller, the linear control gain is determined according to Hopf bifurcation condition. The sym- bolic computing program of normal form direct method （NFDM） is also used to obtain the normal form of the controlled system. The non-linear control gain can be determined based on the relation of the type of bifurcation and the parameters of the normal form, to transform sub-critical Hopf bifurcation to be su- per-critical one. Lastly, numerical simulations are used to certify the validity of theoretical analysis, in which the amplitude of flutter or limit cycle of the controlled system is reduced greatly, comparing to the original system.
文摘Phytoremediation is a cheap and environmentally friendly technique in which green plants in situ are used to clean the soil, sediments and water of heavy metals. This study investigated the phytoremediation potential of six naturally occurring macrophytes from Nange (a stream in Buea municipality where cars have been driven into and washed for over 20 years). Plant samples were collected before and after car wash, then analysed for copper, zinc, lead and cadmium accumulation. There was an increase in concentration of all the four heavy metals in water after carwash point, with Zn having the highest concentration (0.27 mg/L). Mean concentration of the heavy metals in the water showed that Zn and Pb had the highest concentrations (0.24 mg/L each) while the least concentration was obtained in Cu (0.12 mg/kg). Heavy metal concentrations in the sediments were higher after car wash point than before. Cadmium had the highest concentration (5.58 mg/kg) while Cu had the least (0.75 mg/kg). <em>Ludwigia peruviana</em> had the highest BAFs for all the heavy metals (22.95 for Cu, 33.41 for Zn, 21.79 for Pb and 7.85 for Cd). Species with the leasts were: <em>Anubias barteri</em> for Cu (7.16), <em>Polygonum persicaria</em> for Zn (14.28), <em>Rorippa nasturtium-aquaticum</em> for Pb (11.60) and <em>Vallisneria spiralis</em> for Cd (1.98). <em>L. peruviana</em> had the highest BAC values (Cu = 10.11, Zn = 14.73, Pb = 11.39, Cd = 3.85) and BCF values (Cu = 12.84, Zn = 18.67, Pb = 10.40, Cd = 4.00). <em>A. barteri</em> had the highest TF (Cu = 1.49, Zn = 1.27, Cd = 1.99) except for Pb where both <em>A. barteri </em>and <em>L. peruviana</em> each had a TF of 1.10. While all the six plants were found to be good accumulators of the heavy metals, <em>L. peruviana</em> showed remarkable efficiency indicating that the species is a good candidate for cleaning such environments.
文摘Garment washing is a significant area of the apparel industry. Washing is vital for denim and other casual garments for bringing some interesting washed-down effects. Unwashed condition does not exhibit customer’s desired look, but after washing, the same garment becomes prominent in improved appearance, softness, comfort, light and dark shade, and patchy look that creates customer’s absolute satisfaction. Garment washing process increases the appeal with a lucrative outlook brought about by mechanical or chemical treatments in dry or wet conditions. This study gives an indication of different types of washing processes and the change of physical and chemical properties due to application of wet and dry washing processes as an imparting desired effect on garments. The aim of the project is to find out the changes that occur in physical properties of denim when it is subjected to stone enzyme wash on 12-ounce, 10-ounce and 8-ounce denim pants. Three different shades, namely dark shade, medium shade and light wash, were taken into consideration. Different behaviors and properties of the garments were found in the physical properties of the samples.
基金Supports from the National Natural Science Foundation of China under Grant Nos.72348003,72022020 and 71974181the National Social Science Foundation of China under Grant No.20BJL058 are acknowledged.
文摘Greenwashing behaviors(GWBs)in green finance products(GFPs)by enterprises seriously hinder the realization of environmental protection goals.However,methods for effectively regulating GWBs in GFPs are unclear.This study constructed a tripartite evolutionary game model to analyze the formation and governance mechanisms of GWBs in GFPs among regulatory authorities,enterprises,and investors.Subsequently,the stability equilibrium strategy and key factors influencing the system equilibrium were discussed.Several interesting conclusions were drawn.First,we demonstrated that an interdependence mechanism exists among three game agents who mutually influence each other.The larger the probability of regulatory authorities choosing active supervision and investors adopting feedback,the more enterprises are willing to carry out green projects.Second,three corresponding governance modes for GWBs were put forward following the developmental stages of GFPs.Among these,the collaboration mode is the most effective in incentivizing enterprises to implement green projects.Third,based on sensitivity simulations,the initial willingness of the tripartite stakeholders,investor feedback cost,investor compensation,the penalty for greenwashing enterprises,and the reputational benefit of enterprises are critical factors that influence evolutionary results.Finally,targeted countermeasures were provided for regulatory authorities to prevent enterprises from engaging in GWBs.
文摘Simulating the traditional painting art by computer graphics is a challenging and attractive subject. Basing on the experience in the ink wash drawing, in this paper, we expound the artistic characters of ink wash painting and particularly analyze the characteristics of the materials used in the ink wash drawing and the relationships between them. A simulation model is presented and some typical visual effects of the ink wash painting are realized.
文摘AIM： To establish a more sensitive method for detection of free cancer cells in peritoneal washes from gastric cancer patients during surgery and to evaluate its clinical significance. METHODS： The carcinoembryonic antigen （CEA） mRNA levels in peritoneal washes from 65 cases of gastric cancer were detected by real-time RT-PCR. Peritoneal lavage cytology （PLC） was applied simultaneously to detection of free cancer cells. Negative controls included peritoneal washes from 5 cases of benign gastric disease and blood samples from 5 adult healthy volunteers. RESULTS： There was no CEA mRNA in peritoneal washes from benign gastric disease patients and in blood of adult healthy volunteers. The positive percentage of free cancer cells detected by real-time RT-PCR was 47.7% and only 22.3% by PLC. The positive rate of CEA mRNA was significantly related with serosa invasion between peritoneal metastasis and stage of gastric cancer. CONCLUSION： Real-time RT-PCR is a sensitive and rapid method for the detection of free cancer cells in peritoneal washes. The presence of free cancer cells in peritoneal washes is related to the Pathologic stage of gastric cancer.
基金Supported by the Fundamental Research Funds for the Central Universities （FRF-AS-10-001B） and the National Natural Science Foundation of China （11071013）.
文摘method of extracting astaxanthin from Phaffia rhodozyma with various solvents after acid washing was investigated. The extraction efficiency was distinctly increased after acid washing of P. rhodozyma cells. When the concentration of HCl was 0.4 mol.L^-1, the highest extraction efficiency of astaxanthin was achieved which was about three times higher than the control. Acetone or benzene as single polar or non-polar solvent was the most ef- fective solvent in our research. With a combination of isopropanol and n-hexane （volume ratio of 2 ： 1）, the maxi- mal extraction efficiency was achieved, approximately 60% higher than that obtained with a single solvent. The liquid-solid ratio and the extracting time were also optimized. Under the optimum extraction conditions, the extraction yield of astaxanthin exceeded 98%.
文摘BACKGROUND The pathogenesis of gastroesophageal reflux disease(GERD)is closely associated with the intestinal bacteria composition and their metabolites.AIM To investigate whether washed microbiota transplantation(WMT)improves symptoms of nonerosive reflux disease(NERD)with proton pump inhibitor(PPI)dependency.METHODS Patients with recurrent NERD and PPI dependency at the First Affiliated Hospital of Guangdong Pharmaceutical University from 2017 to 2018 were included and divided into a WMT or PPI group treated with PPI with/without WMT.The endpoint was NERD symptom frequency evaluated 1 mo after WMT using reflux disease questionnaire(RDQ)and GERD questionnaire(GERDQ)scores,remission time,PPI dose,and the examination of intestinal mucosal barrier function.RESULTS In the WMT(n=15)and PPI(n=12)groups,the total remission rate at 1 mo after treatment was 93.3%vs 41.7%.Compared with the PPI group,the WMT group showed better results in GERDQ(P=0.004)and RDQ(P=0.003)and in remission months(8 vs 2,P=0.002).The PPI dose was reduced to some extent for 80%of patients in the WMT group and 33.3%in the PPI group.In 24 patients,intestinal mucosal barrier function was examined before treatment,and changes in the degree of damage were observed in 13 of these patients after treatment.Only one of the 15 patients had minor side effects,including a mushy stool two or three times a day,which resolved on their own after 1 wk.CONCLUSION This study is the first to demonstrate that WMT may be safe and effective for relieving NERD symptoms and reducing PPI dependency and recurrence.
文摘Coal Washing Exploration in India dates back to 1900s; though, first coking coal washeries in India were installed after independence. At present, most of the coking coal washeries are owned by Public Sector Companies; whereas, most of the non-coking coal washeries are owned by Private Sector. Even after six decades of coal washing practices, there has not been significant development in the coal washing intelligentsia. Indian Coal Washing industry is still dependent on imported equipment, which has been designed to treat coal that is significantly different from Indian coal of drift origin. In this paper, authors have ventured into evolution of Indian Coal Washing Industry （with a focus on coking coal washing sector）, its present condition and future prospect for growth. The paper emphasizes need for developing indigenous solutions to industrial challenges and highlights importance of increased coordination among academia-research institutions and coal industry.
基金Funded by the National Natural Science Foundation of China(No.20806051)the Key Laboratory of Education Ministry for Solid Waste Management and Environment Safety(No.SWMES-2010-07)the Science and Technology Project of Housing and Urban-Rural Ministry(No.2010-K4-2)
文摘Production of glass-ceramics by sintering the molten slag obtained from electric arc furnace treatment of fly ash was investigated. The effect of washing pretreatment prior to melting the fly ash on the microstructure and properties of the glass-ceramics was examined. The results show that washing pretreatment of fly ash can decrease alkali metal chloride and increase network former in fly ash, which results in the increase of peak crystallization temperature of parent glass and strengthening of properties of bending strength and chemical stability of the glass-ceramics. The optimal heat treatment temperature for parent glass of washed fly ash is 1 173 K, at which the crystalline phase of glass-ceramics is composed of gelignite （Ca2A12SiO7） and akermanite （Ca2MgSi207）. Glass-ceramics produced at optimal heat treatment temperature are excellent in term of the physical and chemical properties and leaching characteristics, indicating attractive potential as substitute of nature materials.
基金Supported by the National Technology Research and Development Program of China(2008AA062402)the China-US International Cooperation Project(2011DFA90800)the Ministry of Science and Technology,China
文摘CO2 removal from biogas by water washing system was investigated with various parameters, including liquid/ gas ratio, pressure, temperature, and CO2 content. The results indicate that CO2 removal ratio could reach 34.6%- 94.2% as liquid/gas ratio increased from 0.14 to 0.50. Increasing pressure （from 0.8 to 1.2 MPa） could improve gas purification with a constant inflow rate of gas. Temperature played a key role in the process and lower temper- ature in absorption tower was beneficial for reducing CO2 content. CO2 removal ratio could reach 24.4%-83.2% when CO2 content in the simulated gas was 25%-45%. The lowest CO2 content after absorption was 2.6% at 1.2 MPa with 400 L·h-1 gas flow and 200 L·h-1 water flow, which meets the requirement of CO2 content in natural Ras for vehicle fuel.
基金Projects(15B054,17C0400) supported by the Scientific Research Fund of Hunan Provincial Education Department,ChinaProjects(2017JJ2060,2015JJ2042) supported by the Natural Science Foundation of Hunan Province,ChinaProject(2014-207) supported by the Aid Program for Science and Technology Innovative Research Team in Higher Educational Instituions of Hunan Province,China
文摘Different LiNi0.8Co0.15Al0.05O2 cathode materials were washed by ethanol solvent. Inductively coupled plasma atomic emission spectroscopy（ICP-AES）, Fourier transformed infrared（FTIR） spectrum, X-ray diffraction（XRD）, scanning electron microscopy（SEM）, charge-discharge test and electrochemical impedance spectroscopy（EIS） were used to evaluate the elemental contents, structures, morphologies and electrochemical properties of samples. The results show that ethanol washing can remove effectively the synthetic residues LiOH/Li2 O on the freshly-prepared LiNi0.8Co0.15Al0.05O2 and make the sample much more resistant to H2O and CO2, without destroying its bulk structure, surface morphology and electrochemical performances. Moreover, the discharge specific capacity and cycle performance of LiNi0.8Co0.15Al0.05O2 after storage in air with a relative humidity of 80% for three months are improved by immediate ethanol washing.
基金the National Natural Science Foundation of China(Grants 11172241 and 11472220).
文摘We conducted experimental and numerical studies on the vibrating modes of a dragon wash basin (DWB) and the free surface waves inside the DWB. Both the vibration of the DWB and the sound produced were studied carefully. It was found that the DWB can be excited at different intrinsic modes under different excitation, including striking and rubbing it fast/slowly. However, with gentle rubbing, the DWB will be excited mainly at the first vibrating mode. We showed that the concave side wall of a DWB decreases the intrinsic frequencies (compared with a straight side wall), and the ears of a DWB lead to breaking of the vibrating-axisymmetry and cause the separation of modes I/II and IV/V as well. A theoretical model, in which the water is assumed to be incompressible and inviscid, is applied to the first order vibration and predicts the relation of vibrating frequency versus water depth in the system. The measurement shows that both the radial and azimuthal waves are produced as DWB is working. The frequency of the first component of the surface wave is twice as large as the second one induced by non-linear effects. For both the radial and azimuthal waves, the dispersion relation is presented in the framework of capillary wave theory.
基金supported by the Special Research Project on Prevention and Control of COVID-19 in Universities of the Guangdong Provincial Education Department(No.2020KZDZX1132).
文摘Objective:Coronavirus disease 2019(COVTD-19)is often accompanied by gastrointestinal symptoms,which are related to gut microbiota dysbiosis(GMD).Whether washed microbiota transplantation(WMT)is an effective treatment for COV1D-19 patients suspected of having GMD by restoring the gut microbiota is unknown.This study is designed to explore the efficacy and safety of WMT in COVID-19 patients suspected of having GMD.Methods:This is a randomized,multicenter,single-blind prospective study.COVID-19 patients suspected of having GMD will be randomly divided to receive routine treatment only or to receive routine treatment and WMT.The frequency of WMT will be once a day for three consecutive days.Laboratory and imaging examinations will be performed at admission,1 and 2 weeks after treatment,and on the day of discharge.Then a telephone follow-up will be conducted at 1st week,2nd week,and 6th month after discharge.The clinical efficacy and safety of WMT in COVD-19 patients suspected of having GMD and the effects of WMT on the organ function,homeostasis,inflammatory response,intestinal mucosal barrier function,and immunity of the patients will be evaluated.Results:By following the proposed protocol,WMT is expected to be efficacious and safe for the treatment of COVID-19 patients suspected of having GMD,and the therapeutic effect is expected to be associated with improvement of the intestinal mucosal barrier function,inflammatory response,and immunity.Conclusion:The findings from this study may offer a new approach for the prevention and treatment of COVID-19 patients suspected of having GMD.
基金supported by the Key Research and Development Project of Shandong Province (No.2015 GSF115005)the Huimin Special Fund of Qingdao Municipal Achievement Transformation Plan (No.15-9-2-120NSH)the National Natural Science Foundation of China (No.31101380)
文摘Water-washing removes fluoride from Antarctic krill but produces large volumes of wash water containing water-soluble proteins and fluoride. The freeze concentration method was tested to determine if it could be used to recover water-soluble proteins while leaving the fluoride in solution. After freezing and thawing the wash water, protein and fluoride contents of the thawed fractions were determined to explore the melting regularity of components in the wash water. The highest concentration factors of protein and fluoride were obtained after 80 min of thawing, such as 1.48 ± 0.06 and 1.35 ± 0.04 times, respectively. The free amino-nitrogen(FAN) content and sodium dodecyl sulfate-polyacrylamide gel electrophoresis pattern results revealed that the highest concentrations of all ingredients were obtained after 80 min of the process. The degree of hydrolysis of all fractions from the thawing process fluctuated in a narrow range around 12% during the entire process, indicating that the thawing order did not change with various proteins or time during the entire thawing course. These results demonstrate that the freeze concentration method can be used to concentrate protein solutions, even those with fluoride. It was concluded that condensation was achieved and no ingredient could be separated, regardless of fluoride, amino acids, or different proteins in the water.
