Elcctrospiiming is a straightforward method to produce micro/nanoscale fibers from polymer solutions typically using an operating voltage of 10 kV 30 kV and spinning distance of 10 cm 20 cm. In this paper, polyvinyl p...Elcctrospiiming is a straightforward method to produce micro/nanoscale fibers from polymer solutions typically using an operating voltage of 10 kV 30 kV and spinning distance of 10 cm 20 cm. In this paper, polyvinyl pyrrolidone （PVP） non-woven nanofibers with diameters of 200 nm 900 nm were prepared by low-voltage near-field electrospinning with a working voltage of less than 2.8 kV and a spinning distance of less than 10 mm. Besides the uniform fibers, beaded-fibers were also fabricated and the formation mechanism was discussed. Particularly, a series of experiments were carried out to explore the influence of processing variables on the formation of near-field electrospun PVP nanofibers, including concentration, humidity, collecting position, and spinning distance.展开更多
Electrospinning is a straightforward method to produce micro/nanoscale fibers from polymer solutions typically using an operating voltage of 10 kV–30 kV and spinning distance of 10 cm–20 cm. In this paper, polyvinyl...Electrospinning is a straightforward method to produce micro/nanoscale fibers from polymer solutions typically using an operating voltage of 10 kV–30 kV and spinning distance of 10 cm–20 cm. In this paper, polyvinyl pyrrolidone (PVP) non-woven nanofibers with diameters of 200 nm–900 nm were prepared by low-voltage near-field electrospinning with a working voltage of less than 2.8 kV and a spinning distance of less than 10 mm. Besides the uniform fibers, beaded-fibers were also fabricated and the formation mechanism was discussed. Particularly, a series of experiments were carried out to explore the influence of processing variables on the formation of near-field electrospun PVP nanofibers, including concentration, humidity, collecting position, and spinning distance.展开更多
In this study,orthogonal experiments were designed to explore the optimal process parameters for preparing polycaprolactone(PCL)scaffolds by the near-field direct-writing melt electrospinning(NFDWMES)technology.Based ...In this study,orthogonal experiments were designed to explore the optimal process parameters for preparing polycaprolactone(PCL)scaffolds by the near-field direct-writing melt electrospinning(NFDWMES)technology.Based on the optimal process parameters,the PCL scaffolds with different thicknesses,gaps and structures were manufactured and the corresponding hydrophilicities were characterized.The PCL scaffolds were modified by chitosan(CS)and hyaluronic acid(HA)to improve biocompatibility and hydrophilicity.Both Fourier transform infrared spectroscopy(FTIR)analysis and antibacterial experimental results show that the chitosan and hyaluronic acid adhere to the surface of PCL scaffolds,suggesting that the modification plays a positive role in biocompatibility and antibacterial effect.The PCL scaffolds were then employed as a carrier to culture cells.The morphology and distribution of the cells observed by a fluorescence microscope demonstrate that the modified PCL scaffolds have good biocompatibility,and the porous structure of the scaffolds is conducive to adhesion and deep growth of cells.展开更多
基金supported by the National Natural Science Foundation of China (Grant Nos. 11074138, 11004114, and 50973098)the Natural Science Foundation of Shandong Province for Distinguished Young Scholars (Grant No. JQ201103)the National Key Basic Research Development Program of China (Grant No. 2012CB722705)
文摘Elcctrospiiming is a straightforward method to produce micro/nanoscale fibers from polymer solutions typically using an operating voltage of 10 kV 30 kV and spinning distance of 10 cm 20 cm. In this paper, polyvinyl pyrrolidone （PVP） non-woven nanofibers with diameters of 200 nm 900 nm were prepared by low-voltage near-field electrospinning with a working voltage of less than 2.8 kV and a spinning distance of less than 10 mm. Besides the uniform fibers, beaded-fibers were also fabricated and the formation mechanism was discussed. Particularly, a series of experiments were carried out to explore the influence of processing variables on the formation of near-field electrospun PVP nanofibers, including concentration, humidity, collecting position, and spinning distance.
基金supported by the National Natural Science Foundation of China (Grant Nos. 11074138, 11004114, and 50973098)the Natural Science Foundation of Shandong Province for Distinguished Young Scholars (Grant No. JQ201103)the National Key Basic Research Development Program of China (Grant No. 2012CB722705)
文摘Electrospinning is a straightforward method to produce micro/nanoscale fibers from polymer solutions typically using an operating voltage of 10 kV–30 kV and spinning distance of 10 cm–20 cm. In this paper, polyvinyl pyrrolidone (PVP) non-woven nanofibers with diameters of 200 nm–900 nm were prepared by low-voltage near-field electrospinning with a working voltage of less than 2.8 kV and a spinning distance of less than 10 mm. Besides the uniform fibers, beaded-fibers were also fabricated and the formation mechanism was discussed. Particularly, a series of experiments were carried out to explore the influence of processing variables on the formation of near-field electrospun PVP nanofibers, including concentration, humidity, collecting position, and spinning distance.
基金This work was supported by the National Science Foundation of China(No.51973168).
文摘In this study,orthogonal experiments were designed to explore the optimal process parameters for preparing polycaprolactone(PCL)scaffolds by the near-field direct-writing melt electrospinning(NFDWMES)technology.Based on the optimal process parameters,the PCL scaffolds with different thicknesses,gaps and structures were manufactured and the corresponding hydrophilicities were characterized.The PCL scaffolds were modified by chitosan(CS)and hyaluronic acid(HA)to improve biocompatibility and hydrophilicity.Both Fourier transform infrared spectroscopy(FTIR)analysis and antibacterial experimental results show that the chitosan and hyaluronic acid adhere to the surface of PCL scaffolds,suggesting that the modification plays a positive role in biocompatibility and antibacterial effect.The PCL scaffolds were then employed as a carrier to culture cells.The morphology and distribution of the cells observed by a fluorescence microscope demonstrate that the modified PCL scaffolds have good biocompatibility,and the porous structure of the scaffolds is conducive to adhesion and deep growth of cells.
