Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propo...Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propose a multi-functional PSHE sensor based on VO_(2), a material that can reveal the phase transition behavior. By applying thermal control, the mutual transformation into different phase states of VO_(2) can be realized, which contributes to the flexible switching between multiple RI sensing tasks. When VO_(2) is insulating, the ultrasensitive detection of glucose concentrations in human blood is achieved. When VO_(2) is in a mixed phase, the structure can be designed to distinguish between the normal cells and cancer cells through no-label and real-time monitoring. When VO_(2) is metallic, the proposed PSHE sensor can act as an RI indicator for gas analytes. Compared with other multi-functional sensing devices with the complex structures, our design consists of only one analyte and two VO_(2) layers, which is very simple and elegant. Therefore, the proposed VO_(2)-based PSHE sensor has outstanding advantages such as small size, high sensitivity, no-label, and real-time detection, providing a new approach for investigating tunable multi-functional sensors.展开更多
BACKGROUND Hepatocellular carcinoma(HCC)ranks as the sixth most common cancer and the third-leading cause of cancer-related deaths worldwide.The multidisciplinary tumor board(MDTB)has been recognized for improving out...BACKGROUND Hepatocellular carcinoma(HCC)ranks as the sixth most common cancer and the third-leading cause of cancer-related deaths worldwide.The multidisciplinary tumor board(MDTB)has been recognized for improving outcomes in cancer management,but its role in patients with HCC undergoing liver transplantation(LT)remains underexplored.AIM To evaluate the impact of an MDTB on survival outcomes in patients with HCC undergoing LT.METHODS We retrospectively analyzed 393 patients with HCC who underwent LT at our institution from October 2015 to October 2021.Patients were categorized into the MDTB and non-MDTB groups.We compared preoperative and postoperative characteristics,overall survival(OS),and disease-free survival(DFS)between the two groups.RESULTS Within the University of California,San Francisco(UCSF)criteria,no significant differences in OS and DFS were noted between the MDTB and non-MDTB groups.However,for patients who exceeded the UCSF criteria,the MDTB group exhibited a substantial improvement in both OS and DFS.The 1-year,3-year,and 5-year OS rates for the MDTB group in this subgroup were 88.68%,75.29%,and 61.78%,respectively,compared to 83.02%,64.07%,and 38.25%,respectively in the non-MDTB group.Similarly,DFS rates were 89.47%,71.35%,and 63.52%,respectively,vs 82.18%,53.78%,and 34.04%,respectively.CONCLUSION The MDTB approach was particularly beneficial for patients with HCC exceeding the UCSF criteria,significantly improving OS and DFS.These findings advocate for integrating MDTB into clinical practice for optimizing the management of high-risk patients with HCC undergoing LT.展开更多
The high labor demand during rice seedling cultivation and transplantation poses a significant challenge in advancing machine-transplanted rice cultivation.This problem may be solved by increasing the seeding rate dur...The high labor demand during rice seedling cultivation and transplantation poses a significant challenge in advancing machine-transplanted rice cultivation.This problem may be solved by increasing the seeding rate during seedling production while reducing the number of seedling trays.This study conducted field experiments from 2021 to 2022,using transplanting seedling ages of 10 and 15 days to explore the effects of 250,300,and 350 g/tray on the seedling quality,mechanical transplantation quality,yields,and economic benefits of rice.The commonly used combination of 150 g/tray with a 20-day seedling age in rice production was used as CK.The cultivation of seedlings under a high seeding rate and short seedling age significantly affected seedling characteristics,but there was no significant difference in seedling vitality compared to CK.The minimum number of rice trays used in the experiment was observed in the treatment of 350-10(300 g/tray and 10-day seedling age),only 152-155 trays ha^(-1),resulting in a 62%reduction in the number of trays needed.By increasing the seeding rate of rice,missed holes during mechanical transplantation decreased by 2.8 to 4%.The treatment of 300-15(300 g/tray and 15-day seedling age)achieved the highest yields and economic gains.These results indicated that using crop straw boards can reduce the application of seedling trays.On that basis,rice yields can be increased by raising the seeding rate and shortening the seedling age of rice without compromising seedling quality.展开更多
This study explores the impact of board diversity on firm performance,with a focus on companies listed on the Singapore Stock Exchange(SGX).Board diversity is examined across various dimensions,including gender,age,et...This study explores the impact of board diversity on firm performance,with a focus on companies listed on the Singapore Stock Exchange(SGX).Board diversity is examined across various dimensions,including gender,age,ethnicity,and professional background,to understand its relationship with key performance indicators such as Return on Assets(ROA)and Return on Equity(ROE).Using a quantitative research approach,the study analyzes data from 90 publicly listed firms,employing descriptive statistics,correlation analysis,and multiple regression techniques.The findings reveal that the direct correlation between board diversity and financial performance,particularly in terms of ROA and ROE,is not statistically significant in the studied sample.Despite the lack of direct significance,the research underscores the nuanced and multifaceted role of diversity in corporate governance,suggesting that its impact may be more complex and influenced by various contextual factors.The study concludes by recommending that companies continue to enhance gender diversity,balance age structures,tailor professional backgrounds to industry needs,and manage board tenure effectively to optimize corporate governance and support sustainable growth.展开更多
The robust magnesium surfaces with multi-functions are highly desirable,and the simple and scalable methods to construct such surfaces are urgently indispensable.Herein,we conducted a one-step spraying method to facil...The robust magnesium surfaces with multi-functions are highly desirable,and the simple and scalable methods to construct such surfaces are urgently indispensable.Herein,we conducted a one-step spraying method to facilely fabricate the robust coating with multi-functions on magnesium alloys.The as-sprayed magnesium alloys surface is superhydrophobic with a static water contact angle(WCA)of 157.0°and a roll-off angle of 6.0°.Such surface has excellent mechanical,chemical and thermal stabilities,even undergoing various physical and chemical damages,including sand impact(10 gmin^(-1),≥20 min),water impact(2 impacts s^(-1),≥180 min),abrasion(1.00 kPa,≥25 cycles),peeling(≥2.15 kPa),high temperature(200°C,≥24 h),strong acidic/salty/basic media(p H=113)and organic-solvent immersion(ethanol and n-hexane,≥24 h),demonstrating brilliant robustness.Notably,the surface displays multi-functions of corrosion protection,anti-fouling and heat insulation,which will undoubtedly promote the much wider applications of magnesium alloys.展开更多
To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforc...To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforced polymer(CFRP)and aluminum components for a robotic aircraft assembly system.To meet the specific functional requirements for blind rivet installation on CFRP and aluminum materials,additional modules are incorporated on the end effector aside of the basic processing modules for drilling.And all of these processing modules allow for a onestep-drilling-countersinking process,hole inspection,automatic rivet feed,rivet geometry check,sealant application,rivet insertion and installation.Besides,to guarantee the better quality of the hole drilled and joints riveted,several online detection and adjustment measures are applied to this end effector,including the reference detection and perpendicular calibration,which could effectively ensure the positioning precision and perpendicular accuracy as demanded.Finally,the test result shows that this end effector is capable of producing each hole to a positioning precision within ±0.5 mm,aperpendicular accuracy within 0.3°,a diameter tolerance of H8,and a countersink depth tolerance of±0.01 mm.Moreover,it could drill and rivet up to three joints per minute,with acceptable shearing and tensile strength.展开更多
Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmo...Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmoplasia causes a hypoxic microenvironment in pancreatic cancer.In this study,a novel FR-directed,macropinocytosis-enhanced,and highly cytotoxic bioconjugate folate(F)-human serum albumin(HSA)-apoprotein of lidamycin(LDP)-active enediyne(AE)derived from lidamycin was designed and prepared.F-HSA-LDP-AE consisted of four moieties:F,HSA,LDP,and AE.F-HSA-LDP presented high binding efficiency with the FR and pancreatic cancer cells.Its uptake in wild-type cells was more extensive than in K-Ras mutant-type cells.By in vivo optical imaging,F-HSA-LDP displayed prominent tumor-specific biodistribution in pancreatic cancer xenograft-bearing mice,showing clear and lasting tumor localization for 360 h.In the MTT assay,F-HSA-LDP-AE demonstrated potent cytotoxicity in three types of pancreatic cancer cell lines.It also induced apoptosis and caused G2/M cell cycle arrest.F-HSALDP-AE markedly suppressed the tumor growth of AsPc-1 pancreatic cancer xenografts in athymic mice.At well-tolerated doses of 0.5 and 1 mg/kg,(i.v.,twice),the inhibition rates were 91.2%and 94.8%,respectively(P<0.01).The results of this study indicate that the F-HSA-LDP multi-functional bioconjugate might be effective for treating K-Ras mutant pancreatic cancer.展开更多
We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain...We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain sensor, and a 48-channel DWDM.This system can monitor temperature and strain changes at the same time.The ranges of these two sensors are from-20℃ to 100℃ and from-1000 με to 2000 με, respectively.The sensitivities of the temperature sensor and strain sensor are 0.03572 nm/℃ and 0.03808 nm/N, respectively.With the aid of a broadband source and spectrometer,different kinds and ranges of parameters in the environment can be monitored by using suitable sensors.展开更多
A compound multi-functional sensor was designed by the study on the on-line testing technology of wood-based panels, and its properties of shape, functions, size, resistance to special environment were studied in deta...A compound multi-functional sensor was designed by the study on the on-line testing technology of wood-based panels, and its properties of shape, functions, size, resistance to special environment were studied in details. The operational principles of different sensors, technical flow of manufacturing, development of software systems of special functions, and the assessments of technical specification were also be introduced. This sensor adopted many new technologies, such as the applications of piezoresistant effect and heat sensitive effect can effectively measure the pressure and temperature, digital signal processing technology was used to extract and treat signals, and resist interference, encapsulation technology was used to keep the normal run of sensor under a harsh environment. Thus, the on-line compound multi-functional temperature/pressure sensor can be applied better to supervise the production of wood-based panels. All technical specifications of the compound multi-functional sensor were tested and the results met the requirements of the equipments.展开更多
A new appraisal method（QDA, quasi-distribution appraisal） which could be used to evaluate the finite element analysis of multi-functional structure made of honeycomb sandwich materials is developed based on sub-sect...A new appraisal method（QDA, quasi-distribution appraisal） which could be used to evaluate the finite element analysis of multi-functional structure made of honeycomb sandwich materials is developed based on sub-section Bezier curve. It is established by simulating the distribution histogram data obtained from the numerical finite element analysis values of a satellite component with sub-section Bezier curve. Being dealt with area normalization method, the simulation curve could be regarded as a kind of probability density function（PDF）, its mathematical expectation and the variance could be used to evaluate the result of finite element analysis. Numerical experiments have indicated that the QDA method demonstrates the intrinsic characteristics of the finite element analysis of multi-functional structure made of honeycomb sandwich materials, as an appraisal method, it is effective and feasible.展开更多
We demonstrate a fiber-loop ring down multi-function sensors system, which can be used to measure refractive index and curvature simultaneously. Good agreement has been found between theoretical analyses and experimen...We demonstrate a fiber-loop ring down multi-function sensors system, which can be used to measure refractive index and curvature simultaneously. Good agreement has been found between theoretical analyses and experimental results. It has great potential for sensor applications.展开更多
Calcium is a critical second messenger molecule in all cells and is vital in neurons for synaptic transmission.Given this importance,calcium ions are tightly controlled by a host of molecular players including ion cha...Calcium is a critical second messenger molecule in all cells and is vital in neurons for synaptic transmission.Given this importance,calcium ions are tightly controlled by a host of molecular players including ion channels,sensors,and buffering proteins.Calcium can act directly by binding to signaling molecules or calcium’s effects can be indirect,for example by altering nuclear histones.展开更多
In order to meet increasing demand for higher productivity and flexibility, recently many kinds of multi-functional machine tools, which are capable of multiple machining functions or different kinds of machining proc...In order to meet increasing demand for higher productivity and flexibility, recently many kinds of multi-functional machine tools, which are capable of multiple machining functions or different kinds of machining processes on one machine, have been developed and widely used in manufacturing industries. In this study, a multi-functional turning lathe, which has two spindles and two turrets so that multiple turning operations and various machining processes could be performed simultaneously, has been developed. Furthermore, the equations of correlation between whole responses and cross responses of the two spindles have been derived to examine to what extent the two spindles affect each other’s vibrations.展开更多
This study presents a design of a multifunctional laparoscopic appendectomy device that includes three surgical instruments commonly used in laparoscopic appendicitis surgeries:endoloop,endobag and scissors.It collect...This study presents a design of a multifunctional laparoscopic appendectomy device that includes three surgical instruments commonly used in laparoscopic appendicitis surgeries:endoloop,endobag and scissors.It collects these three independent surgical tools in a single laparoscopic appendectomy device.These days there is a trend of moving to multi-functional surgery devices during minimally invasive surgery.The main reasons behind the minimal invasive surgery are to avoid changing the devices several times during the operation,to reduce the time spent in operation,to increase the efficiency of the operation,to facilitate the follow-up of the camera and devices,and to leave trocars to be used for other surgical instruments.The multi-functional appendectomy device that,we present here,provides these benefits.The standard trocar entries are appropriate for its usage.The presented multifunctional laparoscopic appendectomy device offers more practical use in comparison to individual devices.On the other hand,development of these multi-functional surgery devices can be directly enhanced to the robotic surgery devices.展开更多
The experimental idea of the present project was elaborated in order to create a structure where different categories and institutions could collaborate, with the common aim to develop a sustainable and profitable agr...The experimental idea of the present project was elaborated in order to create a structure where different categories and institutions could collaborate, with the common aim to develop a sustainable and profitable agriculture in mountain and marginal areas. The target was the recovering of an abandoned agricultural site, throughout its re-organisation, re-qualification and auto-sustainability, involving local citizens. This approach was based on three further broad functions such as environmental, economic and social purposes. This cooperation, that allows the capitalization of local knowledge and the forging of relationships between local and external sources of expertise, information and advice, is fundamental to the future of existing rural communities, in particular in mountain areas. The model proposed, with the elaboration of a management software and technical agronomic sheets, could be an incentive for the activities already present in that region and to stimulate new ones. The enhancing of the native ecological system, the biodiversity tutelage and the valorization of the knowledge of the territory is the basic requirement for the successful of any land management.展开更多
Multi-functioning in virtual monitoring and assessment of ultimate dynamics of thin-walled bridges is treated in present paper. The approach enables multiple functions in virtual monitoring of the bridges made of inte...Multi-functioning in virtual monitoring and assessment of ultimate dynamics of thin-walled bridges is treated in present paper. The approach enables multiple functions in virtual monitoring of the bridges made of integrated thin-walled members with their hierarchical configuration. Theoretical, numerical and experimental in situ assessments of the problem are presented. Some results of structural application are submitted.展开更多
The paper intfoduces a PC-DSP based real-time digital simulator which is portable in size and aimed at the closed-loop testing of various types of protective relays for their design and application. The simulator can ...The paper intfoduces a PC-DSP based real-time digital simulator which is portable in size and aimed at the closed-loop testing of various types of protective relays for their design and application. The simulator can be widely used in not only concerning utilities but also manufacturers and research / certification institutes because of its many functions. The hardware architecture and software implementation of the simulator are described. The main features and functions of the simulator are also展开更多
H-steel all-bolted connection steel frame structures with heat preservation and decoration composite wall boards were investigated and the seismic performances of three scaled specimens were studied.The failure modes,...H-steel all-bolted connection steel frame structures with heat preservation and decoration composite wall boards were investigated and the seismic performances of three scaled specimens were studied.The failure modes,hysteresis curves,bearing capacity,ductility,energy dissipation capacity,stiffness degradation and strain distribution were discussed.The calculation method of structural theoretical internal force was presented.The results showed that the overall structural seismic performance was better,and the structural ductility met the demands of elastic-plastic inter-story drift angle for seismic design.The H-steel weak-axis connection structure obtained better energy dissipation capacity,and its bearing capacity and stiffness were slightly different from the strong-axis connection.The heat preservation and decoration performance of composite wallboard and the all-bolted connection of the steel frame realized prefabrication during the whole construction period.The plastic hinge of the steel beam can be moved outwards because of the L-angles,which effectively avoids stress concentration in joint areas and expands the plastic hinge range.The errors between the theoretical structural capacity calculated by the plastic analysis method and the test results were within 2.44%.In addition,structural failure mechanisms and bearing capacities were verified by the finite element(FE)analysis,and the effects of the main parameters on the structures were investigated.The FE verification results were the same as in the test.The research results provide theoretical support and technical guidance for the application of thermal insulation and decorative composite wall panels in H-shaped steel all-bolted steel frames.展开更多
Oxygen-enriched top-blown smelting is a promising technology for processing waste printed circuit boards(WPCBs).The distribution behavior of valuable elements in WPCBs during smelting was investigated by varying the o...Oxygen-enriched top-blown smelting is a promising technology for processing waste printed circuit boards(WPCBs).The distribution behavior of valuable elements in WPCBs during smelting was investigated by varying the oxygen-enriched concentration,oxygen volume,CaO/SiO_(2)(mass ratio),and Fe/SiO_(2)(mass ratio).The optimal operating conditions were obtained by implementing a one-factor-at-a-time method.X-ray diffractometer,scanning electron microscopy−energy dispersive spectrometer,and inductive coupled plasma-atomic emission spectroscopy methods were utilized to detect the chemical composition,occurrence state as well as elemental contents of alloy and slag.It is found that the elements of Cu,Sn and Ni are mainly accumulated in the alloy while Fe is mainly oxidized into the slag.The direct yields of Cu,Sn and Ni are 90.18%,85.32%and 81.10%under the optimal conditions of temperature 1250℃,oxygen-enriched concentration 30%,oxygen volume 24 L,CaO/SiO_(2) mass ratio 0.55,and Fe/SiO_(2) mass ratio 1.05.The results show that the valuable metals are mainly lost in the slag through mechanical entrainment.展开更多
基金Project supported by the National Natural Science Foundation of China(Grant No.NSFC 12175107)the Natural Science Foundation of Nanjing Vocational University of Industry Technology,China(Grant No.YK22-02-08)+3 种基金the Qing Lan Project of Jiangsu Province,Chinathe Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(Grant No.KYCX23_0964)the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20230347)the Fund from the Research Center of Industrial Perception and Intelligent Manufacturing Equipment Engineering of Jiangsu Province,China(Grant No.ZK21-05-09)。
文摘Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propose a multi-functional PSHE sensor based on VO_(2), a material that can reveal the phase transition behavior. By applying thermal control, the mutual transformation into different phase states of VO_(2) can be realized, which contributes to the flexible switching between multiple RI sensing tasks. When VO_(2) is insulating, the ultrasensitive detection of glucose concentrations in human blood is achieved. When VO_(2) is in a mixed phase, the structure can be designed to distinguish between the normal cells and cancer cells through no-label and real-time monitoring. When VO_(2) is metallic, the proposed PSHE sensor can act as an RI indicator for gas analytes. Compared with other multi-functional sensing devices with the complex structures, our design consists of only one analyte and two VO_(2) layers, which is very simple and elegant. Therefore, the proposed VO_(2)-based PSHE sensor has outstanding advantages such as small size, high sensitivity, no-label, and real-time detection, providing a new approach for investigating tunable multi-functional sensors.
基金Supported by Natural Science Foundation of Tianjin,No.21JCYBJC01140Key Project of Tianjin Science and Technology Bureau Applied Basic Research,No.23JCZDJC01200+1 种基金Key Project of Scientific Research Plan of Tianjin Municipal Education Commission,No.2023YXZD07Project of Tianjin Science and Technology Bureau Applied Basic Research,No.23JCYBJC01800.
文摘BACKGROUND Hepatocellular carcinoma(HCC)ranks as the sixth most common cancer and the third-leading cause of cancer-related deaths worldwide.The multidisciplinary tumor board(MDTB)has been recognized for improving outcomes in cancer management,but its role in patients with HCC undergoing liver transplantation(LT)remains underexplored.AIM To evaluate the impact of an MDTB on survival outcomes in patients with HCC undergoing LT.METHODS We retrospectively analyzed 393 patients with HCC who underwent LT at our institution from October 2015 to October 2021.Patients were categorized into the MDTB and non-MDTB groups.We compared preoperative and postoperative characteristics,overall survival(OS),and disease-free survival(DFS)between the two groups.RESULTS Within the University of California,San Francisco(UCSF)criteria,no significant differences in OS and DFS were noted between the MDTB and non-MDTB groups.However,for patients who exceeded the UCSF criteria,the MDTB group exhibited a substantial improvement in both OS and DFS.The 1-year,3-year,and 5-year OS rates for the MDTB group in this subgroup were 88.68%,75.29%,and 61.78%,respectively,compared to 83.02%,64.07%,and 38.25%,respectively in the non-MDTB group.Similarly,DFS rates were 89.47%,71.35%,and 63.52%,respectively,vs 82.18%,53.78%,and 34.04%,respectively.CONCLUSION The MDTB approach was particularly beneficial for patients with HCC exceeding the UCSF criteria,significantly improving OS and DFS.These findings advocate for integrating MDTB into clinical practice for optimizing the management of high-risk patients with HCC undergoing LT.
基金funded by the Jiangsu Key Research Program,China(BE2022338)the Jiangsu Agricultural Science and Technology Innovation Fund,China(CX(23)3107)+3 种基金the Natural Science Foundation of the Jiangsu Higher Education Institutions,China(22KJB210004)the Jiangsu Province Agricultural Major Technology Collaborative Promotion Project,China(2022-ZYXT-04-1)the Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(KYCX23_3569)the Priority Academic Program Development of Jiangsu Higher Education Institutions,China.
文摘The high labor demand during rice seedling cultivation and transplantation poses a significant challenge in advancing machine-transplanted rice cultivation.This problem may be solved by increasing the seeding rate during seedling production while reducing the number of seedling trays.This study conducted field experiments from 2021 to 2022,using transplanting seedling ages of 10 and 15 days to explore the effects of 250,300,and 350 g/tray on the seedling quality,mechanical transplantation quality,yields,and economic benefits of rice.The commonly used combination of 150 g/tray with a 20-day seedling age in rice production was used as CK.The cultivation of seedlings under a high seeding rate and short seedling age significantly affected seedling characteristics,but there was no significant difference in seedling vitality compared to CK.The minimum number of rice trays used in the experiment was observed in the treatment of 350-10(300 g/tray and 10-day seedling age),only 152-155 trays ha^(-1),resulting in a 62%reduction in the number of trays needed.By increasing the seeding rate of rice,missed holes during mechanical transplantation decreased by 2.8 to 4%.The treatment of 300-15(300 g/tray and 15-day seedling age)achieved the highest yields and economic gains.These results indicated that using crop straw boards can reduce the application of seedling trays.On that basis,rice yields can be increased by raising the seeding rate and shortening the seedling age of rice without compromising seedling quality.
文摘This study explores the impact of board diversity on firm performance,with a focus on companies listed on the Singapore Stock Exchange(SGX).Board diversity is examined across various dimensions,including gender,age,ethnicity,and professional background,to understand its relationship with key performance indicators such as Return on Assets(ROA)and Return on Equity(ROE).Using a quantitative research approach,the study analyzes data from 90 publicly listed firms,employing descriptive statistics,correlation analysis,and multiple regression techniques.The findings reveal that the direct correlation between board diversity and financial performance,particularly in terms of ROA and ROE,is not statistically significant in the studied sample.Despite the lack of direct significance,the research underscores the nuanced and multifaceted role of diversity in corporate governance,suggesting that its impact may be more complex and influenced by various contextual factors.The study concludes by recommending that companies continue to enhance gender diversity,balance age structures,tailor professional backgrounds to industry needs,and manage board tenure effectively to optimize corporate governance and support sustainable growth.
基金supported by the National Natural Science Foundation of China(21773019,21972012)the Graduate Research and Innovation Foundation of Chongqing(CYB18044)the sharing fund of Chongqing University s Large-scale Equipment
文摘The robust magnesium surfaces with multi-functions are highly desirable,and the simple and scalable methods to construct such surfaces are urgently indispensable.Herein,we conducted a one-step spraying method to facilely fabricate the robust coating with multi-functions on magnesium alloys.The as-sprayed magnesium alloys surface is superhydrophobic with a static water contact angle(WCA)of 157.0°and a roll-off angle of 6.0°.Such surface has excellent mechanical,chemical and thermal stabilities,even undergoing various physical and chemical damages,including sand impact(10 gmin^(-1),≥20 min),water impact(2 impacts s^(-1),≥180 min),abrasion(1.00 kPa,≥25 cycles),peeling(≥2.15 kPa),high temperature(200°C,≥24 h),strong acidic/salty/basic media(p H=113)and organic-solvent immersion(ethanol and n-hexane,≥24 h),demonstrating brilliant robustness.Notably,the surface displays multi-functions of corrosion protection,anti-fouling and heat insulation,which will undoubtedly promote the much wider applications of magnesium alloys.
基金supported by the National Natural Science Foundations of China(Nos.5157051626,51475225)
文摘To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforced polymer(CFRP)and aluminum components for a robotic aircraft assembly system.To meet the specific functional requirements for blind rivet installation on CFRP and aluminum materials,additional modules are incorporated on the end effector aside of the basic processing modules for drilling.And all of these processing modules allow for a onestep-drilling-countersinking process,hole inspection,automatic rivet feed,rivet geometry check,sealant application,rivet insertion and installation.Besides,to guarantee the better quality of the hole drilled and joints riveted,several online detection and adjustment measures are applied to this end effector,including the reference detection and perpendicular calibration,which could effectively ensure the positioning precision and perpendicular accuracy as demanded.Finally,the test result shows that this end effector is capable of producing each hole to a positioning precision within ±0.5 mm,aperpendicular accuracy within 0.3°,a diameter tolerance of H8,and a countersink depth tolerance of±0.01 mm.Moreover,it could drill and rivet up to three joints per minute,with acceptable shearing and tensile strength.
基金supported by grants from CAMS Innovation Fund for Medical Sciences(Grant No.:2021-I2M-1-026)Scientific Research Project of Tianjin Education Commission(Grant No.:2020KJ140)Tianjin Health Research Project(Grant No.:KJ20017)。
文摘Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmoplasia causes a hypoxic microenvironment in pancreatic cancer.In this study,a novel FR-directed,macropinocytosis-enhanced,and highly cytotoxic bioconjugate folate(F)-human serum albumin(HSA)-apoprotein of lidamycin(LDP)-active enediyne(AE)derived from lidamycin was designed and prepared.F-HSA-LDP-AE consisted of four moieties:F,HSA,LDP,and AE.F-HSA-LDP presented high binding efficiency with the FR and pancreatic cancer cells.Its uptake in wild-type cells was more extensive than in K-Ras mutant-type cells.By in vivo optical imaging,F-HSA-LDP displayed prominent tumor-specific biodistribution in pancreatic cancer xenograft-bearing mice,showing clear and lasting tumor localization for 360 h.In the MTT assay,F-HSA-LDP-AE demonstrated potent cytotoxicity in three types of pancreatic cancer cell lines.It also induced apoptosis and caused G2/M cell cycle arrest.F-HSALDP-AE markedly suppressed the tumor growth of AsPc-1 pancreatic cancer xenografts in athymic mice.At well-tolerated doses of 0.5 and 1 mg/kg,(i.v.,twice),the inhibition rates were 91.2%and 94.8%,respectively(P<0.01).The results of this study indicate that the F-HSA-LDP multi-functional bioconjugate might be effective for treating K-Ras mutant pancreatic cancer.
基金Project supported by the National Key Research and Development Program of China(Grant No.2016YFB0402504)the National Natural Science Foundation of China(Grant Nos.61875069 and 61575076)+1 种基金Hong Kong Scholars Program,China(Grant No.XJ2016026)the Science and Technology Development Plan of Jilin Province,China(Grant Nos.20190302010GX and 20160520091JH)
文摘We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain sensor, and a 48-channel DWDM.This system can monitor temperature and strain changes at the same time.The ranges of these two sensors are from-20℃ to 100℃ and from-1000 με to 2000 με, respectively.The sensitivities of the temperature sensor and strain sensor are 0.03572 nm/℃ and 0.03808 nm/N, respectively.With the aid of a broadband source and spectrometer,different kinds and ranges of parameters in the environment can be monitored by using suitable sensors.
基金This project was supported by China Postdoctoral Science Funds, Jiangsu Planned Projects for Postdoctoral Research Funds and Northeast Forestry University Research Funds.
文摘A compound multi-functional sensor was designed by the study on the on-line testing technology of wood-based panels, and its properties of shape, functions, size, resistance to special environment were studied in details. The operational principles of different sensors, technical flow of manufacturing, development of software systems of special functions, and the assessments of technical specification were also be introduced. This sensor adopted many new technologies, such as the applications of piezoresistant effect and heat sensitive effect can effectively measure the pressure and temperature, digital signal processing technology was used to extract and treat signals, and resist interference, encapsulation technology was used to keep the normal run of sensor under a harsh environment. Thus, the on-line compound multi-functional temperature/pressure sensor can be applied better to supervise the production of wood-based panels. All technical specifications of the compound multi-functional sensor were tested and the results met the requirements of the equipments.
基金Funded by the National Natural Science Foundation of China(No.61471024)National Marine Technology Program for Public Welfare,China(No.201505002-1)
文摘A new appraisal method（QDA, quasi-distribution appraisal） which could be used to evaluate the finite element analysis of multi-functional structure made of honeycomb sandwich materials is developed based on sub-section Bezier curve. It is established by simulating the distribution histogram data obtained from the numerical finite element analysis values of a satellite component with sub-section Bezier curve. Being dealt with area normalization method, the simulation curve could be regarded as a kind of probability density function（PDF）, its mathematical expectation and the variance could be used to evaluate the result of finite element analysis. Numerical experiments have indicated that the QDA method demonstrates the intrinsic characteristics of the finite element analysis of multi-functional structure made of honeycomb sandwich materials, as an appraisal method, it is effective and feasible.
文摘We demonstrate a fiber-loop ring down multi-function sensors system, which can be used to measure refractive index and curvature simultaneously. Good agreement has been found between theoretical analyses and experimental results. It has great potential for sensor applications.
文摘Calcium is a critical second messenger molecule in all cells and is vital in neurons for synaptic transmission.Given this importance,calcium ions are tightly controlled by a host of molecular players including ion channels,sensors,and buffering proteins.Calcium can act directly by binding to signaling molecules or calcium’s effects can be indirect,for example by altering nuclear histones.
文摘In order to meet increasing demand for higher productivity and flexibility, recently many kinds of multi-functional machine tools, which are capable of multiple machining functions or different kinds of machining processes on one machine, have been developed and widely used in manufacturing industries. In this study, a multi-functional turning lathe, which has two spindles and two turrets so that multiple turning operations and various machining processes could be performed simultaneously, has been developed. Furthermore, the equations of correlation between whole responses and cross responses of the two spindles have been derived to examine to what extent the two spindles affect each other’s vibrations.
文摘This study presents a design of a multifunctional laparoscopic appendectomy device that includes three surgical instruments commonly used in laparoscopic appendicitis surgeries:endoloop,endobag and scissors.It collects these three independent surgical tools in a single laparoscopic appendectomy device.These days there is a trend of moving to multi-functional surgery devices during minimally invasive surgery.The main reasons behind the minimal invasive surgery are to avoid changing the devices several times during the operation,to reduce the time spent in operation,to increase the efficiency of the operation,to facilitate the follow-up of the camera and devices,and to leave trocars to be used for other surgical instruments.The multi-functional appendectomy device that,we present here,provides these benefits.The standard trocar entries are appropriate for its usage.The presented multifunctional laparoscopic appendectomy device offers more practical use in comparison to individual devices.On the other hand,development of these multi-functional surgery devices can be directly enhanced to the robotic surgery devices.
文摘The experimental idea of the present project was elaborated in order to create a structure where different categories and institutions could collaborate, with the common aim to develop a sustainable and profitable agriculture in mountain and marginal areas. The target was the recovering of an abandoned agricultural site, throughout its re-organisation, re-qualification and auto-sustainability, involving local citizens. This approach was based on three further broad functions such as environmental, economic and social purposes. This cooperation, that allows the capitalization of local knowledge and the forging of relationships between local and external sources of expertise, information and advice, is fundamental to the future of existing rural communities, in particular in mountain areas. The model proposed, with the elaboration of a management software and technical agronomic sheets, could be an incentive for the activities already present in that region and to stimulate new ones. The enhancing of the native ecological system, the biodiversity tutelage and the valorization of the knowledge of the territory is the basic requirement for the successful of any land management.
文摘Multi-functioning in virtual monitoring and assessment of ultimate dynamics of thin-walled bridges is treated in present paper. The approach enables multiple functions in virtual monitoring of the bridges made of integrated thin-walled members with their hierarchical configuration. Theoretical, numerical and experimental in situ assessments of the problem are presented. Some results of structural application are submitted.
文摘The paper intfoduces a PC-DSP based real-time digital simulator which is portable in size and aimed at the closed-loop testing of various types of protective relays for their design and application. The simulator can be widely used in not only concerning utilities but also manufacturers and research / certification institutes because of its many functions. The hardware architecture and software implementation of the simulator are described. The main features and functions of the simulator are also
文摘H-steel all-bolted connection steel frame structures with heat preservation and decoration composite wall boards were investigated and the seismic performances of three scaled specimens were studied.The failure modes,hysteresis curves,bearing capacity,ductility,energy dissipation capacity,stiffness degradation and strain distribution were discussed.The calculation method of structural theoretical internal force was presented.The results showed that the overall structural seismic performance was better,and the structural ductility met the demands of elastic-plastic inter-story drift angle for seismic design.The H-steel weak-axis connection structure obtained better energy dissipation capacity,and its bearing capacity and stiffness were slightly different from the strong-axis connection.The heat preservation and decoration performance of composite wallboard and the all-bolted connection of the steel frame realized prefabrication during the whole construction period.The plastic hinge of the steel beam can be moved outwards because of the L-angles,which effectively avoids stress concentration in joint areas and expands the plastic hinge range.The errors between the theoretical structural capacity calculated by the plastic analysis method and the test results were within 2.44%.In addition,structural failure mechanisms and bearing capacities were verified by the finite element(FE)analysis,and the effects of the main parameters on the structures were investigated.The FE verification results were the same as in the test.The research results provide theoretical support and technical guidance for the application of thermal insulation and decorative composite wall panels in H-shaped steel all-bolted steel frames.
基金supported by the National Key R&D Program of China (No.2022YFC2904201)the National Natural Science Foundation of China (Nos.51904124,52004111)+4 种基金Jiangxi Provincial Natural Science Foundation,China (Nos.20224BAB214040,20232BAB204036)the Program of Qingjiang Excellent Young Talents,Jiangxi University of Science and Technology,China (No.JXUSTQJYX2020012)Jiangxi Provincial Cultivation Program for Academic and Technical Leaders of Major Subjects,China (Nos.20212BCJL23052,20212BCJ23006,20212BCJ23007)Double Thousand Plan in Jiangxi Province,China (No.jxsq2019201040)Key Project of Jiangxi Provincial Natural Science Foundation,China (No.20212ACB204015)。
文摘Oxygen-enriched top-blown smelting is a promising technology for processing waste printed circuit boards(WPCBs).The distribution behavior of valuable elements in WPCBs during smelting was investigated by varying the oxygen-enriched concentration,oxygen volume,CaO/SiO_(2)(mass ratio),and Fe/SiO_(2)(mass ratio).The optimal operating conditions were obtained by implementing a one-factor-at-a-time method.X-ray diffractometer,scanning electron microscopy−energy dispersive spectrometer,and inductive coupled plasma-atomic emission spectroscopy methods were utilized to detect the chemical composition,occurrence state as well as elemental contents of alloy and slag.It is found that the elements of Cu,Sn and Ni are mainly accumulated in the alloy while Fe is mainly oxidized into the slag.The direct yields of Cu,Sn and Ni are 90.18%,85.32%and 81.10%under the optimal conditions of temperature 1250℃,oxygen-enriched concentration 30%,oxygen volume 24 L,CaO/SiO_(2) mass ratio 0.55,and Fe/SiO_(2) mass ratio 1.05.The results show that the valuable metals are mainly lost in the slag through mechanical entrainment.
