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Modeling and Validation of Diamagnetic Rotor Levitated by Permanent Magnetics
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作者 Yuanping Xu Yue Zhang +1 位作者 Jin Zhou Chaowu Jin 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第3期224-235,共12页
As an innovative,low-power consuming,and low-stiffness suspension approach,the diamagnetic levitation technique has attracted considerable interest because of its potential applicability in miniaturized mechanical sys... As an innovative,low-power consuming,and low-stiffness suspension approach,the diamagnetic levitation technique has attracted considerable interest because of its potential applicability in miniaturized mechanical systems.The foundation of a diamagnetic levitation system is mathematical modeling,which is essential for operating performance optimization and stability prediction.However,few studies on systematic mathematical modeling have been reported.In this study,a systematic mathematical model for a disc-shaped diamagnetically levitated rotor on a permanent magnet array is proposed.Based on the proposed model,the magnetic field distribution characteristics,diamagnetic levitation force characteristics(i.e.,levitation height and stiffness),and optimized theoretical conditions for realizing stable levitation are determined.Experiments are conducted to verify the feasibility of the proposed mathematical model.Theoretical predictions and experimental results indicate that increasing the levitation height enlarges the stable region.Moreover,with a further increase in the rotor radius,the stable regions of the rotor gradually diminish and even vanish.Thus,when the levitation height is fixed,a moderate rotor radius permits stable levitation.This study proposes a mathematical modeling method for a diamagnetic levitation system that has potential applications in miniaturized mechanical systems. 展开更多
关键词 Diamagnetic levitation Magnetic levitation ROTOR MODELING VALIDATION STABILITY
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Magnetic microbubble:A biomedical platform co-constructed from magnetics and acoustics 被引量:1
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作者 杨芳 顾竹笑 +2 位作者 金熙 王皓瑶 顾宁 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第10期1-12,共12页
Generation of magnetic micrbubbles and their basic magnetic and acoustic mechanism are reviewed. The ultrasound (US) and magnetic resonance (MR) dual imaging, the controlled therapeutic delivery, as well as theran... Generation of magnetic micrbubbles and their basic magnetic and acoustic mechanism are reviewed. The ultrasound (US) and magnetic resonance (MR) dual imaging, the controlled therapeutic delivery, as well as theranostic multifunctions are all introduced based on recent research results. Some on-going research is also discussed. 展开更多
关键词 magnetic nanoparticles MICROBUBBLES magnetic micobubbles magnetics ACOUSTICS biomedicalapplication
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CoEv Magnetics功率电感
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《电子产品世界》 2004年第10B期49-49,共1页
关键词 CoEv magnetics公司 功率电感 电流电感 DZM系列 无铅 RoHS规范 技术规格
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Servo Magnetics低压无刷DC电动机
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《电子产品世界》 2004年第11B期41-41,共1页
Servo Magnetics公司新000—0222无刷DC电机是为那些需要保证经济性和标准NEMA 23接口的低电压工作环境而设计的产品。其工作电压为12V,可以发出25oz—in连续力矩。
关键词 SERVO magnetics公司 无刷DC电动机 技术规格 工作电压
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Conference Information CHINA MAGNETICS 2006
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《China Rare Earth Information》 2006年第5期4-4,共1页
Intertech-Pira has announced that its conference 'China Magnetics 2006' will be held on September 19-21, 2006 at the Sofitel Shanghai Hotel in Shanghai, China. This event is expected to attract over 150 attend... Intertech-Pira has announced that its conference 'China Magnetics 2006' will be held on September 19-21, 2006 at the Sofitel Shanghai Hotel in Shanghai, China. This event is expected to attract over 150 attendees. 展开更多
关键词 OVER Conference Information CHINA magnetics 2006
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PERFORMANCE OF A KIND OF PERMANENT MAGNETICSUCKERSUSED IN WALL- CLIMBING ROBOTS
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作者 仝建刚 马培荪 +1 位作者 包志军 陈俊梅 《Journal of Shanghai Jiaotong university(Science)》 EI 2000年第2期42-46,共5页
The magnetic circuit of a kind of permanent magnetic sucker attached to the tracks of a wall climbing robot was researched. The formula of the attractive force of sucker to a wall was derived and the relationship betw... The magnetic circuit of a kind of permanent magnetic sucker attached to the tracks of a wall climbing robot was researched. The formula of the attractive force of sucker to a wall was derived and the relationship between the force and the air gaps was analyzed. Furthermore the effect of the parameters of the magnetic sucker on the sucker’s performance was discussed. The experiments show that proper selections of the sucker’s structural parameters can provide sufficient attractive force so as to make the wall climbing robot move safely on the steel wall surface. 展开更多
关键词 permanent MAGNETIC SUCKER ATTRACTIVE force MAGNETIC circuit WALL CLIMBING robot Document code:A
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Computational study of combined effects of conduction-radiation and hydromagnetics on natural convection flow past magnetized permeable plate
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作者 M.ASHRAF S.ASGHAR M.A.HOSSAIN 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2012年第6期731-748,共18页
The computational study of the combined effects of radiation and hydro- magnetics on the natural convection flow of a viscous, incompressible, and electrically conducting fluid past a magnetized permeable vertical pla... The computational study of the combined effects of radiation and hydro- magnetics on the natural convection flow of a viscous, incompressible, and electrically conducting fluid past a magnetized permeable vertical plate is presented. The governing non-similar equations are numerically solved by using a finite difference method for all values of the suction parameter and the asymptotic solution for small and large values of ~. The effects of varying the Prandtl number Pr, the magnetic Prandtl number Prm, the magnetic force parameter S, the radiation parameter Rd, and the surface temperature Ow on the coefficients of the skin friction, the rate of heat transfer, and the current density are shown graphically and in tables. An attempt is made to examine the effects of the above mentioned physical parameters on the velocity profile, the temperature distribution, and the transverse component of the magnetic field. 展开更多
关键词 HYDROMAGNETIC fluctuating natural convection magnetized plate currentdensity heat transfer
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Effects of chemical pressure on diluted magneticsemiconductor(Ba,K)(Zn,Mn)_2As_2
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作者 Y Peng S Yu +10 位作者 G Q Zhao W M Li J F Zhao L P Cao X C Wang Q Q Liu S J Zhang R Z Yu Z Deng X H Zhu C Q Jin 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第5期288-292,共5页
Chemical pressure induced by iso-valent doping has been widely employed to tune physical properties of materials. In this work, we report effects of chemical pressure by substitution of Sb or P into As on a recently d... Chemical pressure induced by iso-valent doping has been widely employed to tune physical properties of materials. In this work, we report effects of chemical pressure by substitution of Sb or P into As on a recently discovered diluted magnetic semiconductor(Ba,K)(Zn,Mn)_2 As_2, which has the record of reliable Curie temperature of 230 K due to independent charge and spin doping. Sb and P are substituted into As-site to produce negative and positive chemical pressures, respectively.X-ray diffraction results demonstrate the successful chemical solution of dopants. Magnetic properties of both K-underdoped and K-optimal-doped samples are effectively tuned by Sb-and P-doping. The Hall effect measurements do not show decrease in carrier concentrations upon Sb-and P-doping. Impressively, magnetoresistance is significantly improved from7% to 27% by only 10% P-doping, successfully extending potential application of(Ba,K)(Zn,Mn)_2 As_2. 展开更多
关键词 chemical pressure (Ba K)(Zn Mn)2As2 DILUTED magnetic SEMICONDUCTOR iso-valent DOPING
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A New Form of Quantum Mechanical Wave Equation Unifying Quantum Mechanics and Electro-Magnetics
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作者 Sadegh Angha Sirus Arya Enejad 《Journal of Analytical Sciences, Methods and Instrumentation》 CAS 2022年第2期25-30,共6页
The Schr?dinger differential equation is what we usually solve for the microscopic particles in non-relativistic quantum mechanics. Niels Bohr suggested the power two of the (usually) complex answer shows the probabil... The Schr?dinger differential equation is what we usually solve for the microscopic particles in non-relativistic quantum mechanics. Niels Bohr suggested the power two of the (usually) complex answer shows the probability of the particle’s existence at a point of space. Also, the time dependence of Schrodinger wave equation is one whereas for light in electromagnetism is two. In this paper, we show a solution for both problems. We derive a Wave Equation for the energy of every system. This electromagnetic wave equation is shown to convert to those classical (i.e. the Schrodinger) and special relativistic (i.e. Klein-Gordon) quantum mechanical equations. Also, accordingly there definitely is a physical meaning to answer to this wave equation. And therefore, switching the probabilistic interpretation of quantum mechanics to a deterministic one as (Albert) Einstein demanded. 展开更多
关键词 Quantum Mechanics Electricity & Magnetism Wave Equations Probabilistic vs Deterministic Presentations
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Integration of Ground Magnetics and Energy Dispersive X-Ray Fluorescence Spectroscopy in Ilmenite Prospection in Magaoni, Kenya
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作者 George Oduor Otieno John Gitonga Githiri Willis Jakanyango Ambusso 《Open Journal of Applied Sciences》 2016年第2期79-88,共10页
The geology of Magaoni area is associated with the presence of heavy minerals [1]. Magaoni’s neighbours Maumba and Nguluku where ilmenite was discovered by Tiomin Resource Inc. in 1996, using drilling and chemical an... The geology of Magaoni area is associated with the presence of heavy minerals [1]. Magaoni’s neighbours Maumba and Nguluku where ilmenite was discovered by Tiomin Resource Inc. in 1996, using drilling and chemical analysis [2]. Ilmenite mineral is known to be magnetically weak, but provides observable magnetic response [3]. In this study, ground magnetic survey method was carried out to map magnetic anomalies of established stations, associated with ilmenite bearing formations. The magnetic contour map plotted showed weak and shallow magnetic signatures spread throughout the study area. 2D Euler deconvolution solutions revealed presence of magnetised formations from near surface to a maximum depth of about 450 m at some points. The weak magnetic formations of near surface indicated presence of ilmenite. Energy dispersive X-ray spectroscopy was done on soil samples collected randomly from the study area to determine the percentage of iron and titanium oxides. The results showed elevated values of titanium dioxide, ranging from 1.5% to 13% which is way above the global average of about 0.7% [4]. The percentage of iron oxide was low, ranging from 1.5% to 4%, this being the reason for weak magnetisation of the study area. 展开更多
关键词 ILMENITE Magnetic Survey Euler Deconvolution SPECTROSCOPY
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Overview of Planar Magnetics for High-frequency Resonant Converters 被引量:1
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作者 Yue Liu Yufeng Song +3 位作者 Dingfan Hu Yang Li Zuoqian Zhang Hongfei Wu 《Chinese Journal of Electrical Engineering》 CSCD 2022年第4期61-78,共18页
With the continuous development of power supplies toward miniaturization,light weights,and high levels of integration,research on high-frequency resonant conversion based on planar magnetics is becoming extensive.Comb... With the continuous development of power supplies toward miniaturization,light weights,and high levels of integration,research on high-frequency resonant conversion based on planar magnetics is becoming extensive.Combining the soft-switching characteristics of resonant converters with those of wide bandgap devices,the switching frequency can be increase to the MHz range,and the power density of the entire system can be improved considerably.However,higher switching frequencies impose new requirements for the structural design,loss distribution,and common mode(CM)noise suppression of passive magnetic components.Herein,a thorough survey of the-state-of-the-art of planar magnetics in high-frequency resonant converters is conducted.Printed circuit board winding-based planar magnetics,magnetic integration,and power-loss optimization strategies are summarized in detail.Suppression methods for CM noise in high-frequency planar magnetics are also clarified and discussed.An insight view into the future development of planar magnetics for high-frequency resonant converters is presented. 展开更多
关键词 Planar magnetics resonant converter matrix transformer magnetic integration PCB winding loss model loss measurement CM noise suppression
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Low‑Temperature Oxidation Induced Phase Evolution with Gradient Magnetic Heterointerfaces for Superior Electromagnetic Wave Absorption
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作者 Zizhuang He Lingzi Shi +6 位作者 Ran Sun Lianfei Ding Mukun He Jiaming Li Hua Guo Tiande Gao Panbo Liu 《Nano-Micro Letters》 SCIE EI CAS 2025年第1期191-204,共14页
Gradient magnetic heterointerfaces have injected infinite vitality in optimizing impedance matching,adjusting dielectric/magnetic resonance and promoting electromagnetic(EM)wave absorption,but still exist a significan... Gradient magnetic heterointerfaces have injected infinite vitality in optimizing impedance matching,adjusting dielectric/magnetic resonance and promoting electromagnetic(EM)wave absorption,but still exist a significant challenging in regulating local phase evolution.Herein,accordion-shaped Co/Co_(3)O_(4)@N-doped carbon nanosheets(Co/Co_(3)O_(4)@NC)with gradient magnetic heterointerfaces have been fabricated via the cooperative high-temperature carbonization and lowtemperature oxidation process.The results indicate that the surface epitaxial growth of crystal Co_(3)O_(4) domains on local Co nanoparticles realizes the adjustment of magnetic-heteroatomic components,which are beneficial for optimizing impedance matching and interfacial polarization.Moreover,gradient magnetic heterointerfaces simultaneously realize magnetic coupling,and long-range magnetic diffraction.Specifically,the synthesized Co/Co_(3)O_(4)@NC absorbents display the strong electromagnetic wave attenuation capability of−53.5 dB at a thickness of 3.0 mm with an effective absorption bandwidth of 5.36 GHz,both are superior to those of single magnetic domains embedded in carbon matrix.This design concept provides us an inspiration in optimizing interfacial polarization,regulating magnetic coupling and promoting electromagnetic wave absorption. 展开更多
关键词 Magnetic heterointerfaces Phase evolution Interfacial polarization Magnetic coupling Electromagnetic wave absorption
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Construction of iron manganese metal-organic framework-derived manganese ferrite/carbon-modified graphene composites toward broadband and efficient electromagnetic dissipation 被引量:1
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作者 Baohua Liu Shuai Liu +1 位作者 Zaigang Luo Ruiwen Shu 《International Journal of Minerals,Metallurgy and Materials》 2025年第3期546-555,共10页
The preparation of carbon-based electromagnetic wave(EMW)absorbers possessing thin matching thickness,wide absorption bandwidth,strong absorption intensity,and low filling ratio remains a huge challenge.Metal-organic ... The preparation of carbon-based electromagnetic wave(EMW)absorbers possessing thin matching thickness,wide absorption bandwidth,strong absorption intensity,and low filling ratio remains a huge challenge.Metal-organic frameworks(MOFs)are ideal self-sacrificing templates for the construction of carbon-based EMW absorbers.In this work,bimetallic FeMn-MOF-derived MnFe_(2)O_(4)/C/graphene composites were fabricated via a two-step route of solvothermal reaction and the following pyrolysis treatment.The results re-veal the evolution of the microscopic morphology of carbon skeletons from loofah-like to octahedral and then to polyhedron and pomegran-ate after the adjustment of the Fe^(3+)to Mn^(2+)molar ratio.Furthermore,at the Fe^(3+)to Mn^(2+)molar ratio of 2:1,the obtained MnFe_(2)O_(4)/C/graphene composite exhibited the highest EMW absorption capacity.Specifically,a minimum reflection loss of-72.7 dB and a max-imum effective absorption bandwidth of 5.1 GHz were achieved at a low filling ratio of 10wt%.In addition,the possible EMW absorp-tion mechanism of MnFe_(2)O_(4)/C/graphene composites was proposed.Therefore,the results of this work will contribute to the construction of broadband and efficient carbon-based EMW absorbers derived from MOFs. 展开更多
关键词 metal-organic frameworks GRAPHENE magnetic composites morphology regulation electromagnetic dissipation
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Review of recent advances in ferrite-based materials:From synthesis techniques to electromagnetic wave absorption performance 被引量:1
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作者 Xingliang Chen Di Lan +5 位作者 Luoting Zhou Hailing Liu Xiyu Song Shouyu Wang Zhuanyong Zou Guanglei Wu 《International Journal of Minerals,Metallurgy and Materials》 2025年第3期591-608,共18页
With the booming development of electronic information science and 5G communication technology,electromagnetic radi-ation pollution poses a huge threat and damage to humanity.Developing novel and high-performance elec... With the booming development of electronic information science and 5G communication technology,electromagnetic radi-ation pollution poses a huge threat and damage to humanity.Developing novel and high-performance electromagnetic wave(EMW)ab-sorbers is an effective method to solve the above issue and has attracted the attention of many researchers.As a typical magnetic material,ferrite plays an important role in the design of high-performance EMW absorbers,and related research focuses on diversified synthesis methods,strong absorption performance,and refined microstructure development.Herein,we focus on the synthesis of ferrites and their composites and introduce recent advances in the high-temperature solid-phase method,sol-gel method,chemical coprecipitation method,and solvent thermal method in the preparation of high-performance EMW absorbers.This review aims to help researchers understand the advantages and disadvantages of ferrite-based EMW absorbers fabricated through these methods.It also provides important guidance and reference for researchers to design high-performance EMW absorption materials based on ferrite. 展开更多
关键词 FERRITE electromagnetic wave absorber sol-gel method magnetic material solvent thermal method
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Imaging characteristics of hypervascular focal nodular hyperplasialike lesions in patients with chronic alcoholic liver disease
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作者 Atsushi Urase Masakatsu Tsurusaki +3 位作者 Ryohei Kozuki Atsushi Kono Keitaro Sofue Kazunari Ishii 《World Journal of Gastroenterology》 SCIE CAS 2025年第2期61-70,共10页
BACKGROUND Focal nodular hyperplasia(FNH)-like lesions are hyperplastic formations in patients with micronodular cirrhosis and a history of alcohol abuse.Although pathologically similar to hepatocellular carcinoma(HCC... BACKGROUND Focal nodular hyperplasia(FNH)-like lesions are hyperplastic formations in patients with micronodular cirrhosis and a history of alcohol abuse.Although pathologically similar to hepatocellular carcinoma(HCC)lesions,they are benign.As such,it is important to develop methods to distinguish between FNH-like lesions and HCC.AIM To evaluate diagnostically differential radiological findings between FNH-like lesions and HCC.METHODS We studied pathologically confirmed FNH-like lesions in 13 patients with alco-holic cirrhosis[10 men and 3 women;mean age:54.5±12.5(33-72)years]who were negative for hepatitis-B surface antigen and hepatitis-C virus antibody and underwent dynamic computed tomography(CT)and magnetic resonance imaging(MRI),including superparamagnetic iron oxide(SPIO)and/or gadoxetic acid-enhanced MRI.Seven patients also underwent angiography-assisted CT.RESULTS The evaluated lesion features included arterial enhancement pattern,washout appearance(low density compared with that of surrounding liver parenchyma),signal intensity on T1-weighted image(T1WI)and T2-weighted image(T2WI),central scar presence,chemical shift on in-and out-of-phase images,and uptake pattern on gadoxetic acid-enhanced MRI hepatobiliary phase and SPIO-enhanced MRI.Eleven patients had multiple small lesions(<1.5 cm).Radiological features of FNH-like lesions included hypervascularity despite small lesions,lack of“corona-like”enhancement in the late phase on CT during hepatic angiography(CTHA),high-intensity on T1WI,slightly high-or iso-intensity on T2WI,no signal decrease in out-of-phase images,and complete SPIO uptake or incomplete/partial uptake of gadoxetic acid.Pathologically,similar to HCC,FNH-like lesions showed many unpaired arteries and sinusoidal capillarization.CONCLUSION Overall,the present study showed that FNH-like lesions have unique radiological findings useful for differential diagnosis.Specifically,SPIO-and/or gadoxetic acid-enhanced MRI and CTHA features might facilitate differential diagnosis of FNH-like lesions and HCC. 展开更多
关键词 Focal nodular hyperplasia Alcoholic liver disease Hepatocellular carcinoma Magnetic resonance imaging LIVER
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An embedded electron current layer observed at the edge of the plasma sheet in the Earth’s magnetotail
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作者 ChenChen Zhan RongSheng Wang +2 位作者 QuanMing Lu San Lu XinMin Li 《Earth and Planetary Physics》 EI CAS 2025年第1期148-158,共11页
The formation of an embedded electron current sheet within the magnetotail plasma sheet has been poorly understood.In this article,we present an electron current layer detected at the edge of the magnetotail plasma sh... The formation of an embedded electron current sheet within the magnetotail plasma sheet has been poorly understood.In this article,we present an electron current layer detected at the edge of the magnetotail plasma sheet.The ions were demagnetized inside the electron current layer,but the electrons were still frozen in with the magnetic field line.Thus,this decoupling of ions and electrons gave rise to a strong Hall electric field,which could be the reason for the formation of the embedded thin current layer.The magnetized electrons,the absence of the nongyrotropic electron distribution,and negligible energy dissipation in the layer indicate that magnetic reconnection had not been triggered within the embedded thin current layer.The highly asymmetric plasma on the two sides of the current layer and low magnetic shear across it could suppress magnetic reconnection.The observations indicate that the embedded electric current layer,probably generated by the Hall electric field,even down to electron scale,is not a sufficient condition for magnetic reconnection. 展开更多
关键词 MAGNETOTAIL plasma sheet magnetic reconnection
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Temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries on magnetic resonance imaging
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作者 Holly Flyger Samantha J.Holdsworth +2 位作者 Alistair J.Gunn Laura Bennet Hamid Abbasi 《Neural Regeneration Research》 SCIE CAS 2025年第11期3144-3150,共7页
Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental disability.Detailed asse... Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental disability.Detailed assessment is important to help identify highrisk infants,to help families,and to support appropriate interventions.A wide range of monitoring tools is available to assess changes over time,including urine and blood biomarkers,neurological examination,and electroencephalography.At present,magnetic resonance imaging is unique as although it is expensive and not suited to monitoring the early evolution of hypoxic-ischemic encephalopathy by a week of life it can provide direct insight into the anatomical changes in the brain after hypoxic-ischemic encephalopathy and so offers strong prognostic information on the long-term outcome after hypoxic-ischemic encephalopathy.This review investigated the temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries,with a particular emphasis on exploring the correlation between the prognostic implications of magnetic resonance imaging scans in the first week of life and their relationship to long-term outcome prediction,particularly for infants treated with therapeutic hypothermia.A comprehensive literature search,from 2016 to 2024,identified 20 pertinent articles.This review highlights that while the optimal timing of magnetic resonance imaging scans is not clear,overall,it suggests that magnetic resonance imaging within the first week of life provides strong prognostic accuracy.Many challenges limit the timing consistency,particularly the need for intensive care and clinical monitoring.Conversely,although most reports examined the prognostic value of scans taken between 4 and 10 days after birth,there is evidence from small numbers of cases that,at times,brain injury may continue to evolve for weeks after birth.This suggests that in the future it will be important to explore a wider range of times after hypoxic-ischemic encephalopathy to fully understand the optimal timing for predicting long-term outcomes. 展开更多
关键词 magnetic resonance imaging neonatal hypoxic-ischemic encephalopathy neurodevelopmental outcomes prognostic biomarkers in neuroimaging scan timing therapeutic hypothermia
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Progress of research in the application of ultrasound technology for the treatment of Alzheimer’s disease
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作者 Qiuquan Cai Lianghui Meng +5 位作者 Meina Quan Ling Wang Jing Ren Chenguang Zheng Jiajia Yang Dong Ming 《Neural Regeneration Research》 SCIE CAS 2025年第10期2823-2837,共15页
Alzheimer’s disease is a common neurodegenerative disorder defined by decreased reasoning abilities,memory loss,and cognitive deterioration.The presence of the blood-brain barrier presents a major obstacle to the dev... Alzheimer’s disease is a common neurodegenerative disorder defined by decreased reasoning abilities,memory loss,and cognitive deterioration.The presence of the blood-brain barrier presents a major obstacle to the development of effective drug therapies for Alzheimer’s disease.The use of ultrasound as a novel physical modulation approach has garnered widespread attention in recent years.As a safe and feasible therapeutic and drug-delivery method,ultrasound has shown promise in improving cognitive deficits.This article provides a summary of the application of ultrasound technology for treating Alzheimer’s disease over the past 5 years,including standalone ultrasound treatment,ultrasound combined with microbubbles or drug therapy,and magnetic resonance imaging-guided focused ultrasound therapy.Emphasis is placed on the benefits of introducing these treatment methods and their potential mechanisms.We found that several ultrasound methods can open the blood-brain barrier and effectively alleviate amyloid-βplaque deposition.We believe that ultrasound is an effective therapy for Alzheimer’s disease,and this review provides a theoretical basis for future ultrasound treatment methods. 展开更多
关键词 Alzheimer’s disease blood-brain barrier DRUGS magnetic resonance imaging-guided focused ultrasound MICROBUBBLES scanning ultrasound ULTRASOUND ultrasound stimulation
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Repetitive transcranial magnetic stimulation in Alzheimer’s disease:effects on neural and synaptic rehabilitation
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作者 Yi Ji Chaoyi Yang +7 位作者 Xuerui Pang Yibing Yan Yue Wu Zhi Geng Wenjie Hu Panpan Hu Xingqi Wu Kai Wang 《Neural Regeneration Research》 SCIE CAS 2025年第2期326-342,共17页
Alzheimer’s disease is a neurodegenerative disease resulting from deficits in synaptic transmission and homeostasis.The Alzheimer’s disease brain tends to be hyperexcitable and hypersynchronized,thereby causing neur... Alzheimer’s disease is a neurodegenerative disease resulting from deficits in synaptic transmission and homeostasis.The Alzheimer’s disease brain tends to be hyperexcitable and hypersynchronized,thereby causing neurodegeneration and ultimately disrupting the operational abilities in daily life,leaving patients incapacitated.Repetitive transcranial magnetic stimulation is a cost-effective,neuro-modulatory technique used for multiple neurological conditions.Over the past two decades,it has been widely used to predict cognitive decline;identify pathophysiological markers;promote neuroplasticity;and assess brain excitability,plasticity,and connectivity.It has also been applied to patients with dementia,because it can yield facilitatory effects on cognition and promote brain recovery after a neurological insult.However,its therapeutic effectiveness at the molecular and synaptic levels has not been elucidated because of a limited number of studies.This study aimed to characterize the neurobiological changes following repetitive transcranial magnetic stimulation treatment,evaluate its effects on synaptic plasticity,and identify the associated mechanisms.This review essentially focuses on changes in the pathology,amyloidogenesis,and clearance pathways,given that amyloid deposition is a major hypothesis in the pathogenesis of Alzheimer’s disease.Apoptotic mechanisms associated with repetitive transcranial magnetic stimulation procedures and different pathways mediating gene transcription,which are closely related to the neural regeneration process,are also highlighted.Finally,we discuss the outcomes of animal studies in which neuroplasticity is modulated and assessed at the structural and functional levels by using repetitive transcranial magnetic stimulation,with the aim to highlight future directions for better clinical translations. 展开更多
关键词 Alzheimer’s disease amyloid deposition apoptotic mechanisms BIOMARKER neural regeneration NEURODEGENERATION repetitive transcranial magnetic stimulation synaptic plasticity
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Multisensory mechanisms of gait and balance in Parkinson’s disease:an integrative review
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作者 Stiven Roytman Rebecca Paalanen +4 位作者 Giulia Carli Uros Marusic Prabesh Kanel Teus van Laar Nico I.Bohnen 《Neural Regeneration Research》 SCIE CAS 2025年第1期82-92,共11页
Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have ... Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging population.Posture and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous mechanisms.To effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory signals.The mechanisms which underpin the integration of these multisensory signals are the principal topic of the present work.Existing multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older adults.Insufficient emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and balance.In the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s disease.We also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older adults.Lastly,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases. 展开更多
关键词 aging BALANCE encephalography functional magnetic resonance imaging GAIT multisensory integration Parkinson’s disease positron emission tomography SOMATOSENSORY VESTIBULAR visual
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