AIM:To estimate the cost-benefit of endoscopic screening strategies of esophageal cancer(EC)in high-risk areas of China. METHODS:Markov model-based analyses were conducted to compare the net present values(NPVs)and th...AIM:To estimate the cost-benefit of endoscopic screening strategies of esophageal cancer(EC)in high-risk areas of China. METHODS:Markov model-based analyses were conducted to compare the net present values(NPVs)and the benefit-cost ratios(BCRs)of 12 EC endoscopic screening strategies.Strategies varied according to the targeted screening age,screening frequencies,and follow-up intervals.Model parameters were collected from population-based studies in China,published literatures,and surveillance data. RESULTS:Compared with non-screening outcomes,all strategies with hypothetical 100 000 subjects saved life years.Among five dominant strategies determined by the incremental cost-effectiveness analysis,screening once at age 50 years incurred the lowest NPV(international dollar-I$55 million)and BCR(2.52).Screening six times between 40-70 years at a 5-year interval[i.e., six times(40)f-strategy]yielded the highest NPV(I$99 million)and BCR(3.06).Compared with six times(40)fstrategy,screening thrice between 40-70 years at a 10-year interval resulted in relatively lower NPV,but the same BCR. CONCLUSION:EC endoscopic screening is cost-beneficial in high-risk areas of China.Policy-makers should consider the cost-benefit,population acceptance,and local economic status when choosing suitable screening strategies.展开更多
ABSTRACT In year 2000, a book entitled the Pathology and Genetics of Tumors of the Digestive System was published by the WHO, presenting some new diagnostic criteria and treatment principles. I have analyzed the epide...ABSTRACT In year 2000, a book entitled the Pathology and Genetics of Tumors of the Digestive System was published by the WHO, presenting some new diagnostic criteria and treatment principles. I have analyzed the epidemiologic change of tumors in over 30 years in the high-risk area with esophageal cancer. The following phenomenon was found: accompanied by the sharp decrease in the incidence and mortality of esophageal cancer, there was an increase in the incidence and death rate of stomach cancer involving cardiac cancer. This fact should be considered when analyzing the sharp decrease in esophageal cancer incidence and mortality rate. More attention was given to diagnosis of cardiac cancer; at the same time it is more practical to improve the early screening of cancers. To observe the development of high and low - grade intraepithelial neoplasms will be an urgent task for esophageal cancer research in the high risk area, according to WHO's new classification.展开更多
Objective: Given the unique cultural background, way of life, and physical environment of the Tibetan Plateau, this study aims to investigate the effects of health education using problem-based learning (PBL) approach...Objective: Given the unique cultural background, way of life, and physical environment of the Tibetan Plateau, this study aims to investigate the effects of health education using problem-based learning (PBL) approaches on the knowledge, attitude, practice, and coping skills of women with high-risk pregnancies in this region. Methods: 76 high-risk pregnancy cases were enrolled at Tibet’s Linzhi People’s Hospital between September 2023 and April 2024. 30 patients admitted between September 2023 and December 2023 were selected as the control group and were performed with regular patient education. 46 patients admitted between January 2024 and April 2024 were selected as the observation group and were performed regular patient education with problem-based learning approaches. Two groups’ performance on their health knowledge, attitude, practice and coping skills before and after interventions were evaluated, and patient satisfaction were measured at the end of the study. Results: There was no statistical significance (P P P Conclusions: Health education with problem-based learning approaches is worth promoting as it can help high-risk pregnant women in plateau areas develop better health knowledge, attitude and practice and healthier coping skills. Also, it can improve patient sanctification.展开更多
Objective:To explore the perspectives of high-risk pregnant women regarding the home care program for high-risk pregnancies.Methods:This qualitative study was conducted in a university hospital and 5 comprehensive hea...Objective:To explore the perspectives of high-risk pregnant women regarding the home care program for high-risk pregnancies.Methods:This qualitative study was conducted in a university hospital and 5 comprehensive health centers in Ahvaz,Iran,from February 2023 to July 2023.The sampling method used was purposive sampling considering the maximum possible diversity,which continued until data saturation.11 in-depth and semistructured interviews were conducted with high-risk pregnant women.Data were simultaneously analysed using Graneheim and Lundman content analysis by MAXQDA version 20 software.Results:Data analysis extracted 3 themes,12 categories,and 26 subcategories.The themes and categories were“high-risk pregnancy and related issues(pursuing treatment and paying attention to the high-risk situation by pregnant women,psychological aspect of high-risk pregnancy on pregnant women and caregivers,emotional and physical aspects of high-risk pregnancy,the consequences of high-risk pregnancy on the people around them and empowerment of high-risk pregnant women)”,“support dimension(family and community support for high-risk pregnant women)”,and“framework of program(acculturalization,means and equipment,security,manpower and the necessary arrangements for the home care)”.Conclusions:High-risk pregnancy affects various aspects of the lives of high-risk pregnant women and their families.Creating the necessary conditions for providing care at home plays a vital role in supporting high-risk pregnant women and removing related obstacles to receiving prenatal care in person.It will be especially beneficial for high-risk pregnant women in low-income areas.展开更多
Objective: Stroke is perceived as a serious illness although it is preventable, and lifestyle alterations can be made to reduce its risk. Improvement of stroke care should be achieved through awareness of public, espe...Objective: Stroke is perceived as a serious illness although it is preventable, and lifestyle alterations can be made to reduce its risk. Improvement of stroke care should be achieved through awareness of public, especially through high-risk group. Henceforth, the aim of this study was to evaluate the effect of nursing intervention on improving awareness of high-risk people about stroke prevention. Methods: A quasi-experimental design was used to carry out this study, where a purposive sample of 80 adult patients at high risk for stroke were enrolled while they were attending the out-patient clinics of Zagazig University Hospitals for follow-up treatment;they were divided into two groups: case (40 patients) and control (40 patients). An interview questionnaire was used to assess patients’ knowledge regarding warning signs, risk factors, and immediate treatment;attitude;and their practice for prevention for stroke at pretest and posttest. Results: The study revealed the poor level of knowledge, bad level of preventive behavior, and negative attitude regarding stroke prevention at pre-intervention. However, after intervention, the high-risk people had fair level of knowledge with moderate practice for stroke prevention and positive attitude, with statistically significant difference between pre-post intervention and between the case and control groups. Conclusions: The study revealed that the nursing intervention seemed to change the knowledge, practice, and attitude of subjects regarding stroke prevention. This, in turn, implies that awareness of prevention of stroke and high-risk factor control could be important to reduce the burden of stroke in Egypt. Thus, further research on a larger scale is required to improve population knowledge and behavior for stroke prevention and control.展开更多
In Niger, irrigated agriculture constitutes the main alternative for meeting family needs. It is within this framework that the state and its partners have adopted strategies to promote irrigated production sites. Thi...In Niger, irrigated agriculture constitutes the main alternative for meeting family needs. It is within this framework that the state and its partners have adopted strategies to promote irrigated production sites. This study was carried out on the Konni irrigated perimeter, the objective of which is to analyze the physical state of hydraulic infrastructures and their operation before the rehabilitation of the said perimeter. The methodology adopted consisted, first of all, of documentary research focused on data relating to this scope and our theme to properly guide the collection of data in the field. The field phase was then followed with an observation of hydraulic infrastructures one by one in order to assess their condition. Thus, the collected data was processed and analyzed. The results of this study show a notable deterioration of hydraulic infrastructure which affected the operating yield of the study area, with the development of barely 700 ha out of 1226 ha planned by the basic study for off-season production (57%). Bathymetric measurements showed that the volume of sediment that accumulated in the Zongo Dam is 1.2 million m3, which reduces its initial capacity from 12 million m3 to 10.8 million m3 after 43 years of service. The expansion joints of the feed canal are all in poor condition. 90% of the total length of the tertiary canals are degraded, 82.32% of the panels of the main canal C are degraded and 17.68% are cracked. All crossing structures are blocked between the RN1 and the Zongo dam. Based on this critical situation, it would be essential to consider rehabilitation work on all infrastructure in order to restore the hydraulic and even agronomic performance of the Konni irrigated area.展开更多
Diuron (N-(3,4-dichlorophenyl)-N,N-dimethylurea) is one among the booster biocides substituted tributyltin as an antifouling agent. It has continued to be used ever since, though little is known about their levels in ...Diuron (N-(3,4-dichlorophenyl)-N,N-dimethylurea) is one among the booster biocides substituted tributyltin as an antifouling agent. It has continued to be used ever since, though little is known about their levels in the maritime setting of Zanzibar. This paper details the occurrence and distribution of diuron around the coastline of Zanzibar Island. The reported concentrations of diuron in water ranged from Below Detection Limit to 1321.67 ± 52.3 ng/L at Bwawani. Majority of the sites showed levels above Environmental Risk Limit of 430 ng/L as proposed by the Dutch Authorities. The findings suggest the contamination is elevated especial in Harbor, Bwawani, Chapwani and even at Marine Protected Areas such Mnemba Island where the value of 620.33 ± 5.70 ng/L was recorded. The main possible sources of the contamination are cargo shipping, passenger speedboats, fishing, and tourism activities taking places in these areas. Therefore, future studies on the antifouling biocide diuron particularly on long term monitoring, chronic exposure, risk assessment, organisms’ responses and pollution models will add special value towards better understanding of the mechanisms and sustainable marine ecosystem health.展开更多
Research on habitat quality in ecologically vulnerable areas has gained attention due to mountain urbanization and climate change. However, the absence of comprehensive reviews limits a systematic understanding of hab...Research on habitat quality in ecologically vulnerable areas has gained attention due to mountain urbanization and climate change. However, the absence of comprehensive reviews limits a systematic understanding of habitat quality. This study investigates habitat quality research in ecologically vulnerable regions of China, drawing data from Web of Science and Scopus. Using CiteSpace software analyzes trends in publication volume, geographic distribution, journal outlets, research disciplines, and keyword co-occurrence. The findings identify two distinct research phases: an initial exploratory stage and a period of steady growth, with the Loess Plateau emerging as a primary focal region. Key journals, such as Ecological Indicators and Acta Ecologica Sinica, dominate the field, reflecting contributions from disciplines including environmental science and ecology. Research hotspots center on trade-offs between habitat quality and ecosystem services, driving factors of change, landscape pattern optimization, and simulation techniques. Future research should prioritize addressing the spatial heterogeneity of vulnerable regions, advancing methodological approaches, and enhancing uncertainty analyses in model parameterization. This study provides a critical foundation for addressing key scientific challenges and guiding future research, with implications for ecological security and sustainable development.展开更多
BACKGROUND Effective health management for high-risk stroke populations is essential.The hospital-community-home(HCH)collaborative health management(CHM)model leverages resources from hospitals,communities,and familie...BACKGROUND Effective health management for high-risk stroke populations is essential.The hospital-community-home(HCH)collaborative health management(CHM)model leverages resources from hospitals,communities,and families.By integrating patient information across these three domains,it facilitates the delivery of tailored guidance,health risk assessments,and three-in-one health education.AIM To explore the effects of the HCH-CHM model on stroke risk reduction in highrisk populations.METHODS In total,110 high-risk stroke patients screened in the community from January 2019 to January 2023 were enrolled,with 52 patients in the control group receiving routine health education and 58 in the observation group receiving HCH-CHM model interventions based on routine health education.Stroke awareness scores,health behavior levels,medication adherence,blood pressure,serum biochemical markers(systolic/diastolic blood pressure,total cholesterol,and triglyceride),and psychological measures(self-rating anxiety/depression scale)were evaluated and compared between groups.RESULTS The observation group showed statistically significant improvements in stroke awareness scores and health behavior levels compared to the control group(P<0.05),with notable enhancements in lifestyle and dietary habits(P<0.05)and reductions in postintervention systolic blood pressure,diastolic blood pressure,total cholesterol,triglyceride,self-rating anxiety scale,and self-rating depression scale scores(P<0.05).CONCLUSION The HCH-CHM model had a significant positive effect on high-risk stroke populations,effectively increasing disease awareness,improving health behavior and medication adherence,and appropriately ameliorating blood pressure,serum biochemical marker levels,and negative psychological symptoms.展开更多
BACKGROUND Inadequately controlled hypertension often leads to an increased cardiovascular death rate in type 2 diabetes mellitus(T2DM).It remains unclear whether systolic blood pressure(SBP)status of hypertension is ...BACKGROUND Inadequately controlled hypertension often leads to an increased cardiovascular death rate in type 2 diabetes mellitus(T2DM).It remains unclear whether systolic blood pressure(SBP)status of hypertension is related to coronary inflammation and plaques in T2DM.AIM To evaluate whether SBP variability(SBPV)and levels of hypertension are related to coronary inflammation and plaques in T2DM patients using coronary computed tomography angiography(CCTA).METHODS This retrospective study involved 881 T2DM patients with CCTA images,including 668 hypertension and 213 normotension patients.Hypertension patients were subgroup based on SBP status:(1)SBPV:Low(<8.96 mmHg)and high(≥8.96 mmHg)groups;and(2)SBP levels:Controlled(<140 mmHg)and uncontrolled(≥140 mmHg)groups.Pericoronary adipose tissue(PCAT)attenuation,high-risk plaques(HRPs)and obstructive stenosis(OS)were evaluated by CCTA.Propensity score matching was utilized to compare these CCTA findings for these groups.The impact of SBPV and SBP levels of hypertension on these CCTA findings in T2DM patients were evaluated by multivariate logistic regression and multivariable linear regression.RESULTS PCAT attenuation of the left anterior descending artery(LAD),any low attenuation plaque(LAP),any spotty calcification(SC),any positive remodeling(PR),and OS had significant differences between the hypertension group and the normotension group,as well as between the high SBPV or uncontrolled SBP group and the low SBPV or controlled SBP group(all P<0.05).Hypertension was independently positively correlated with LADPCAT attenuation(β=1.815,P=0.010),LAP(OR=1.612,P=0.019),SC(OR=1.665,P=0.013),PR(OR=1.549,P=0.033),and OS(OR=1.928,P=0.036)in all T2DM patients.Additionally,high SBPV and uncontrolled SBP were independently positively correlated with LAD-PCAT attenuation(high SBPV:β=1.673,P=0.048;uncontrolled SBP:β=2.370,P=0.004)and PR(high SBPV:OR=1.903,P=0.048;uncontrolled SBP:OR=2.230,P=0.013)in T2DM patients with hypertension.CONCLUSION Inadequately controlled hypertension,including high SBPV and/or uncontrolled SBP levels,may be related to increased coronary artery inflammation,HRPs,and OS in T2DM,leading to increased cardiovascular risk.Achieving both low SBPV and controlled SBP levels simultaneously,especially in individuals with T2DM and hypertension,warrants clinical attention.展开更多
The gap between the projected urban areas in the current trend(UAC)and those in the sustainable scenario(UAS)is a critical factor in understanding whether cities can fulfill the requirements of sustainable development...The gap between the projected urban areas in the current trend(UAC)and those in the sustainable scenario(UAS)is a critical factor in understanding whether cities can fulfill the requirements of sustainable development.However,there is a paucity of knowledge on this cutting-edge topic.Given the extensive and rapid urbanization in the United States(U.S.)over the past two centuries,accurately measuring this gap between UAS and UAC is of critical importance for advancing future sustainable urban development,as well as having significant global implications.This study finds that although the 740 U.S.cities have a large UAC in 2100,these cities will encom pass a significant gap from UAC to UAS(approximately 165,000 km2),accounting for 30%UAC at that time.The study also reveals the spatio-temporal heterogeneity of the gap.The gap initially increases before reaching a inflection point in 2090,and it disparates greatly from−100%to 240%at city level.While cities in the Northwestern U.S.maintain UAC that exceeds UAS from 2020 to 2100,cities in other regions shift from UAC that exceeds UAS to UAC that falls short of UAS.Filling the gap without additional urban growth planning could lead to a reduction of crop production ranging from 0.3%to 3%and a 0.68%loss of biomass.Hence,dynamic and forward-looking urban planning is essential for addressing the challenges of sustainable development posed by urbanization,both within the U.S.and globally.展开更多
In the context of rapid urbanization,cities must leverage their unique advantages to enhance their competitiveness.It has become a prevalent practice to integrate Chinese cultural elements into a city’s brand identit...In the context of rapid urbanization,cities must leverage their unique advantages to enhance their competitiveness.It has become a prevalent practice to integrate Chinese cultural elements into a city’s brand identity,as well as to transform and elevate the existing landscape.This paper examines the landscape evolution of Nanchang Bayi Park(Baihuazhou)and the associated measures for its transformation and enhancement.The findings indicate that,from the perspective of urban visual art,these transformations significantly enhance the city’s aesthetic perception and more effectively address the needs of people.Consequently,this contributes to the ongoing improvement and development of the city’s brand image.By modifying the urban structure,enhancing the urban environment,upgrading infrastructure,and elevating the cultural levels within urban areas,the objective of transforming and upgrading urban landscapes can be realized.展开更多
Alkaline igneous rocks represent one of the most economically important resources of radioactive minerals and rare metals.New field observations and petrographic studies are integrated with whole-rock geochemical anal...Alkaline igneous rocks represent one of the most economically important resources of radioactive minerals and rare metals.New field observations and petrographic studies are integrated with whole-rock geochemical analyses and Gamma ray spectroscopy data of alkaline rocks associated with the Amreit complex.The fieldwork was achieved by the collection of more than forty samples from alkaline granites and alkaline syenites.The youngest rocks cropping out in the study area are the cogenetic alkaline rocks,ranging from alkaline granite to alkaline syenite.These alkaline rocks are composed essentially of K-feldspar,alkali amphiboles(arfvedsonite),and sodic pyroxene,with accessories such as zircon,apatite,and ilmenite.Mineral characterization of the highly radioactive zones in both alkaline granite and alkaline syenite displays enrichment in monazite,thorite,zircon,ferro-columbite,xenotime,and allanite minerals.Geochemical analyses indicate that the Amreit rocks are alkaline with peralkaline affinity and have high concentrations of total alkalis(K_(2)O+Na_(2)O),large ion lithophile elements(LILEs;Ba and Rb),high field strength elements(HFSEs;Y,Zr and Nb),rare earth elements(REEs)and significantly depleted in K,Sr,P,Ti,and Eu,typically of post-collision A-type granites.Typically,the Amreit alkaline igneous rocks are classified as within plate granites and display A2 subtype characteristics.The fractionation of K-feldspars played a distinctive role during the magmatic evolution of these alkaline rocks.The geochemical characteristics indicate that the studied alkaline igneous rocks which were originated by fractional crystallization of alkaline magmas were responsible for the enrichment of the REE and rare metals in the residual melt.The high radioactivity is essentially related to accessory minerals,such as zircon,allanite,and monazite.The alkaline granite is the most U-and Thrich rock,where radioactivity level reaches up to 14.7 ppm(181.55 Bq/kg)e U,40.6 ppm(164.84 Bq/kg)e Th,whereas in alkaline syenite radioactivity level is 8.5 ppm(104.96 Bq/kg)e U,30.2 ppm(122.61 Bq/kg)e Th.These observations suppose that these alkaline rocks may be important targets for REEs and radioactive mineral exploration.展开更多
Background:Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. While liver transplantation (LT) provides the best long-term survival, it is constrained by organ scarcity and strict criteria....Background:Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. While liver transplantation (LT) provides the best long-term survival, it is constrained by organ scarcity and strict criteria. Liver resection (LR) is often the initial treatment for patients with solitary tumors and preserved liver function. The high recurrence rates associated with LR has prompted the exploration of sequential living donor liver transplantation (seq LDLT) after LR as a strategy for HCC patients with high-risk of recurrence.Methods:We analyzed data from 27 adult patients who underwent seq LDLT after LR for HCC at Kaohsiung Chang Gung Memorial Hospital (KCGMH) between June 1994 and December 2023. Patients were selected based on high-risk histopathological features post-LR or as part of downstaging strategy. Outcomes measured included overall survival (OS) and disease-free survival (DFS).Results:Among 765 HCC patients who underwent LDLT, 204 received LR before LDLT, and 27 underwent seqL DLT. Five patients (19%) underwent living donor liver transplantation (LDLT) following LR as a downstaging strategy while the rest received seqL DLT as a preemptive strategy. The median age was 53.5 years with 85%males. Chronic hepatitis B was the predominant underlying disease (74%). The 1-, 3-, and 5-year OS and DFS rates were 100%, 96.0%, 96.0%and 100%, 96.2%, 96.2%, respectively, with two patients experiencing HCC recurrence. One patient died from HCC recurrence. High-risk histopathological features included microvascular invasion (52%), satellite nodules (15%), multiple tumors (26%), tumors> 5 cm(19%), and a total tumor diameter> 10 cm (7%).Conclusions:Seq LDLT offers a promising, tailored approach for managing HCC with adverse histopathologic features. Combining seq LDLT, downstaging strategies, and multidisciplinary treatments can achieve satisfactory OS and DFS in carefully selected patients, highlighting the need for refined criteria to identify the best candidates.展开更多
Assessment of SDG11.3.1 indicator of the United Nations Sustainable Development Goals(SDGs)is a valuable tool for policymakers in urban planning.This study aims to enhance the accuracy of the SDG11.3.1 evaluation and ...Assessment of SDG11.3.1 indicator of the United Nations Sustainable Development Goals(SDGs)is a valuable tool for policymakers in urban planning.This study aims to enhance the accuracy of the SDG11.3.1 evaluation and explore the impact of varying precision levels in urban built-up area on the indicator’s assessment outcomes.We developed an algorithm to generate accurate urban built-up area data products based on China’s Geographical Condition Monitoring data with a 2 m resolution.The study evaluates urban land-use efficiency in China from 2015 to 2020 across different geographical units using both the research product and data derived from other studies utilizing medium and low-resolution imagery.The results indicate:(1)A significant improvement in the accuracy of our urban built-up area data,with the SDG11.3.1 evaluation results demonstrating a more precise reflection of spatiotemporal characteristics.The indicator shows a positive correlation with the accuracy level of the built-up area data;(2)From 2015 to 2020,Chinese prefecture-level cities have undergone faster urbanization in terms of land expansion relative to population growth,leading to less optimal land resource utilization.Only in extra-large cities does urban population growth show a relatively balanced pattern.However,urban popula tion growth in other regions and cities of various sizes lags behind land urbanization.Notably,Northeast China and small to medium cities encounter significant challenges in urban population growth.The comprehensive framework developed for evaluating SDG11.3.1 with high-precision urban built-up area data can be adapted to different national regions,yielding more accurate SDG11.3.1 outcomes.Our urban area and built-up area data products provide crucial inputs for calculating at least four indicators related to SDG11.展开更多
The Tarim Basin has revealed numerous tight sandstone oil and gas reservoirs.The tidal fl at zone in the Shunbei area is currently in the detailed exploration stage,requiring a comprehensive description of the sand bo...The Tarim Basin has revealed numerous tight sandstone oil and gas reservoirs.The tidal fl at zone in the Shunbei area is currently in the detailed exploration stage,requiring a comprehensive description of the sand body distribution characteristics for rational exploration well deployment.However,using a single method for sand body prediction has yielded poor results.Seismic facies analysis can eff ectively predict the macro-development characteristics of sedimentary sand bodies but lacks the resolution to capture fi ne details.In contrast,single-well sedimentary facies analysis can describe detailed sand body development but struggles to reveal broader trends.Therefore,this study proposes a method that combines seismic facies analysis with single-well sedimentary microfacies analysis,using the lower section of the Kepingtage Formation in the Shunbei area as a case study.First,seismic facies were obtained through unsupervised vector quantization to control the macro-distribution characteristics of sand bodies,while principal component analysis(PCA)was applied to improve the depiction of fi ne sand body details from seismic attributes.Based on 3D seismic data,well-logging data,and geological interpretation results,a detailed structural interpretation was performed to establish a high-precision stratigraphic framework,thereby enhancing the accuracy of sand body prediction.Seismic facies analysis was then conducted to obtain the macro-distribution characteristics of the sand bodies.Subsequently,core data and logging curves from individual wells were used to clarify the vertical development characteristics of tidal channels and sandbars.Next,PCA was employed to select the seismic attributes most sensitive to sand bodies in diff erent sedimentary facies.Results indicate that RMS amplitude in the subtidal zone and instantaneous phase in the intertidal zone are the most sensitive to sand bodies.A comparative analysis of individual seismic attributes for sand body characterization revealed that facies-based delineation improved the accuracy of sand body identifi cation,eff ectively capturing their contours and shapes.This method,which integrates seismic facies,single-well sedimentary microfacies,and machine learning techniques,enhances the precision of sand body characterization and off ers a novel approach to sand body prediction.展开更多
The Majiagou Formation in the Fuxian area of the southeastern Ordos Basin has undergone a complex diagenetic evolution history under the influence of eustacy and the Caledonian karstification,resulting in several comp...The Majiagou Formation in the Fuxian area of the southeastern Ordos Basin has undergone a complex diagenetic evolution history under the influence of eustacy and the Caledonian karstification,resulting in several complex reservoir types.Through analyses of mineralogy,petrology,and reservoir geology,three major types of dolomite reservoirs with different genetic mechanisms,including anhydritic moldicdissolved pore type,dolomitic intercrystalline-pore type,and fractured type were identified,and their formation mechanisms and distribution patterns were examined.The aphanocrystalline to very finecrystalline anhydritic dolomite was resulted from Sabhak dolomitization,and is characterized by small size of crystals and high content of anhydrite.Dolomite reservoirs of anhydritic moldic-dissolved pore type were developed in multi-stage dissolution processes and mainly distributed at higher positions of the paleogeomorphology where the filling was weak.The very fine to fine-crystalline dolomite of shoal facies was formed under seepage-reflux dolomitization,and characterized by larger sizes of crystals and well-developed intercrystalline pores.Dolomite reservoirs of intercrystalline-pore type were mainly developed at the lower positions of the paleogeomorphology where bedding-parallel karst dissolution was strong.The fractured dolomite reservoirs,generated by the anhydrite swelling and karst cave collapse,occur in multiple horizons but within limited areas due to multi-stage fillings.展开更多
This paper presents a standardised workflow for conducting hazard assessments of mass wasting processes in remote mountain areas with limited data.The methodology integrates geomorphological mapping and remote sensing...This paper presents a standardised workflow for conducting hazard assessments of mass wasting processes in remote mountain areas with limited data.The methodology integrates geomorphological mapping and remote sensing techniques and is adaptable to different national standards,thus ensuring its applicability in a variety of contexts.The principal objective is to guarantee the safety of mountainous regions,particularly in the vicinity of essential infrastructure,where the scope for implementing structural measures is restricted.The framework commences with comprehensive geomorphological mapping,which facilitates the identification of past hazardous processes and potential future hazards.New technologies,such as uncrewed aerial vehicles(UAVs),are employed to create high-resolution DEMs,which are particularly beneficial in regions with limited data availability.These models facilitate the assessment of potential hazards and inform decisions regarding protective measures.The utilisation of UAVs enhances the accuracy and efficiency of data collection,particularly in remote mountainous regions where alternative remotely sensed information may be unavailable.The integration of modern approaches into traditional hazard assessment methods allows for a comprehensive analysis of the spatial distribution of factors driving mass wasting processes.This workflow provides valuable insights that assist in the prioritisation of interventions and the optimisation of risk reduction in high mountainous areas.展开更多
RBOE is a new type of DNAN-based high-energy melt-cast mixed explosive,whose safety under thermal stimulation is significantly affected by heating conditions and venting area of the warhead.Based on the thermal decomp...RBOE is a new type of DNAN-based high-energy melt-cast mixed explosive,whose safety under thermal stimulation is significantly affected by heating conditions and venting area of the warhead.Based on the thermal decomposition reaction characteristics and combustion characteristics of each component of RBOE explosive,the cook-off calculation models of RBOE warhead before and after ignition were established.In addition,closed and vented warheads were designed,as well as fast and slow cook-off test devices.The cook-off characteristics and thermal safety venting area of RBOE warhead were extensively studied.The results showed that the closed RBOE warhead underwent deflagration reaction under both slow and fast cook-off conditions.The calculation result of the shell wall temperature before slow cookoff ignition response of the warhead was 454.06 K,with an error of+1.75%compared to the test result of462.15 K,and the temperature rise rate calculated was in good agreement with the test.The calculated ignition time of RBOE warhead under fast cook-off was 161 s,with an error of+8.8%compared to the test result of 148 s,which verified the accuracy of cook-off model of RBOE warhead before ignition.According to the cook-off calculation model of the warhead after ignition and cook-off test of the vented warhead,it was determined that the thermal safety venting area was 1124.61 mm^(2)for fast cook-off and 530.66 mm~2 for slow cook-off,effectively preventing the reaction of warhead above combustion.Therefore,this study provides a scientific basis for the thermal safety design and evaluation of insensitive warheads.展开更多
Deforestation remains one of the most imminent threats to biodiversity in the tropics.As such,its causes and dynamics need to be studied and understood to put a halt to further forest loss and degradation.In tropical ...Deforestation remains one of the most imminent threats to biodiversity in the tropics.As such,its causes and dynamics need to be studied and understood to put a halt to further forest loss and degradation.In tropical countries such as Uganda,agricultural expansion and wood fuel demand are its leading drivers.While the establishment of protected areas is a key tool in conserving remaining forest biodiversity,results indicate that current management does not sufficiently provide alternatives to forest resources utilised by households and income provided from timber and non-timber forest products.Beyond safeguarding ecosystems,protected areas need to ensure the sustainable socioeconomic development of adjacent communities for effective biodiversity conservation–however,both management and research often neglect to consider all dimensions.In this study,we analysed five decades of forest cover change in the Mount Elgon region,Uganda,by conducting a remote sensing analysis of its protected areas using Landsat MSS and TM data from 1973-2023 in combination with literature and subsequent interview analysis to consider both the ecological and socioeconomic dimension.We applied a random forest approach to differentiate forest and non-forest areas and carried out a pixel-based change detection analysis to differentiate temporal and spatial changes.Throughout the study period of 50 years,forest cover has evolved dynamically within the boundaries of the protected areas of Mount Elgon.A significant decline was observed in both Mount Elgon National Park with a loss of-5.98%(-46.83km²)and Mount Elgon Biosphere Reserve with a loss of-14.96%(-134.33km²).Our results showcase a cycle of deforestation and afforestation that could be tied to a series of development initiatives,re-demarcation of boundaries,changes in management and recurring evictions.Overall,the results lead to the conclusion that the lack of sustainable and efficient management and funding has fostered the rate of deforestation and accelerated ecological degradation in the region,but that existing problems are also rooted in the land tenure history of the region.We recommend the proper implementation of participatory and long-term management approaches on the ground and to address the land rights issue to contribute to both socioeconomic wellbeing and sustainable conservation outcomes.展开更多
基金Supported by The National Science and Technology Pillar Program of the 11th National Five-Year Plan of China,No. 2006BAI02A15
文摘AIM:To estimate the cost-benefit of endoscopic screening strategies of esophageal cancer(EC)in high-risk areas of China. METHODS:Markov model-based analyses were conducted to compare the net present values(NPVs)and the benefit-cost ratios(BCRs)of 12 EC endoscopic screening strategies.Strategies varied according to the targeted screening age,screening frequencies,and follow-up intervals.Model parameters were collected from population-based studies in China,published literatures,and surveillance data. RESULTS:Compared with non-screening outcomes,all strategies with hypothetical 100 000 subjects saved life years.Among five dominant strategies determined by the incremental cost-effectiveness analysis,screening once at age 50 years incurred the lowest NPV(international dollar-I$55 million)and BCR(2.52).Screening six times between 40-70 years at a 5-year interval[i.e., six times(40)f-strategy]yielded the highest NPV(I$99 million)and BCR(3.06).Compared with six times(40)fstrategy,screening thrice between 40-70 years at a 10-year interval resulted in relatively lower NPV,but the same BCR. CONCLUSION:EC endoscopic screening is cost-beneficial in high-risk areas of China.Policy-makers should consider the cost-benefit,population acceptance,and local economic status when choosing suitable screening strategies.
文摘ABSTRACT In year 2000, a book entitled the Pathology and Genetics of Tumors of the Digestive System was published by the WHO, presenting some new diagnostic criteria and treatment principles. I have analyzed the epidemiologic change of tumors in over 30 years in the high-risk area with esophageal cancer. The following phenomenon was found: accompanied by the sharp decrease in the incidence and mortality of esophageal cancer, there was an increase in the incidence and death rate of stomach cancer involving cardiac cancer. This fact should be considered when analyzing the sharp decrease in esophageal cancer incidence and mortality rate. More attention was given to diagnosis of cardiac cancer; at the same time it is more practical to improve the early screening of cancers. To observe the development of high and low - grade intraepithelial neoplasms will be an urgent task for esophageal cancer research in the high risk area, according to WHO's new classification.
文摘Objective: Given the unique cultural background, way of life, and physical environment of the Tibetan Plateau, this study aims to investigate the effects of health education using problem-based learning (PBL) approaches on the knowledge, attitude, practice, and coping skills of women with high-risk pregnancies in this region. Methods: 76 high-risk pregnancy cases were enrolled at Tibet’s Linzhi People’s Hospital between September 2023 and April 2024. 30 patients admitted between September 2023 and December 2023 were selected as the control group and were performed with regular patient education. 46 patients admitted between January 2024 and April 2024 were selected as the observation group and were performed regular patient education with problem-based learning approaches. Two groups’ performance on their health knowledge, attitude, practice and coping skills before and after interventions were evaluated, and patient satisfaction were measured at the end of the study. Results: There was no statistical significance (P P P Conclusions: Health education with problem-based learning approaches is worth promoting as it can help high-risk pregnant women in plateau areas develop better health knowledge, attitude and practice and healthier coping skills. Also, it can improve patient sanctification.
文摘Objective:To explore the perspectives of high-risk pregnant women regarding the home care program for high-risk pregnancies.Methods:This qualitative study was conducted in a university hospital and 5 comprehensive health centers in Ahvaz,Iran,from February 2023 to July 2023.The sampling method used was purposive sampling considering the maximum possible diversity,which continued until data saturation.11 in-depth and semistructured interviews were conducted with high-risk pregnant women.Data were simultaneously analysed using Graneheim and Lundman content analysis by MAXQDA version 20 software.Results:Data analysis extracted 3 themes,12 categories,and 26 subcategories.The themes and categories were“high-risk pregnancy and related issues(pursuing treatment and paying attention to the high-risk situation by pregnant women,psychological aspect of high-risk pregnancy on pregnant women and caregivers,emotional and physical aspects of high-risk pregnancy,the consequences of high-risk pregnancy on the people around them and empowerment of high-risk pregnant women)”,“support dimension(family and community support for high-risk pregnant women)”,and“framework of program(acculturalization,means and equipment,security,manpower and the necessary arrangements for the home care)”.Conclusions:High-risk pregnancy affects various aspects of the lives of high-risk pregnant women and their families.Creating the necessary conditions for providing care at home plays a vital role in supporting high-risk pregnant women and removing related obstacles to receiving prenatal care in person.It will be especially beneficial for high-risk pregnant women in low-income areas.
文摘Objective: Stroke is perceived as a serious illness although it is preventable, and lifestyle alterations can be made to reduce its risk. Improvement of stroke care should be achieved through awareness of public, especially through high-risk group. Henceforth, the aim of this study was to evaluate the effect of nursing intervention on improving awareness of high-risk people about stroke prevention. Methods: A quasi-experimental design was used to carry out this study, where a purposive sample of 80 adult patients at high risk for stroke were enrolled while they were attending the out-patient clinics of Zagazig University Hospitals for follow-up treatment;they were divided into two groups: case (40 patients) and control (40 patients). An interview questionnaire was used to assess patients’ knowledge regarding warning signs, risk factors, and immediate treatment;attitude;and their practice for prevention for stroke at pretest and posttest. Results: The study revealed the poor level of knowledge, bad level of preventive behavior, and negative attitude regarding stroke prevention at pre-intervention. However, after intervention, the high-risk people had fair level of knowledge with moderate practice for stroke prevention and positive attitude, with statistically significant difference between pre-post intervention and between the case and control groups. Conclusions: The study revealed that the nursing intervention seemed to change the knowledge, practice, and attitude of subjects regarding stroke prevention. This, in turn, implies that awareness of prevention of stroke and high-risk factor control could be important to reduce the burden of stroke in Egypt. Thus, further research on a larger scale is required to improve population knowledge and behavior for stroke prevention and control.
文摘In Niger, irrigated agriculture constitutes the main alternative for meeting family needs. It is within this framework that the state and its partners have adopted strategies to promote irrigated production sites. This study was carried out on the Konni irrigated perimeter, the objective of which is to analyze the physical state of hydraulic infrastructures and their operation before the rehabilitation of the said perimeter. The methodology adopted consisted, first of all, of documentary research focused on data relating to this scope and our theme to properly guide the collection of data in the field. The field phase was then followed with an observation of hydraulic infrastructures one by one in order to assess their condition. Thus, the collected data was processed and analyzed. The results of this study show a notable deterioration of hydraulic infrastructure which affected the operating yield of the study area, with the development of barely 700 ha out of 1226 ha planned by the basic study for off-season production (57%). Bathymetric measurements showed that the volume of sediment that accumulated in the Zongo Dam is 1.2 million m3, which reduces its initial capacity from 12 million m3 to 10.8 million m3 after 43 years of service. The expansion joints of the feed canal are all in poor condition. 90% of the total length of the tertiary canals are degraded, 82.32% of the panels of the main canal C are degraded and 17.68% are cracked. All crossing structures are blocked between the RN1 and the Zongo dam. Based on this critical situation, it would be essential to consider rehabilitation work on all infrastructure in order to restore the hydraulic and even agronomic performance of the Konni irrigated area.
文摘Diuron (N-(3,4-dichlorophenyl)-N,N-dimethylurea) is one among the booster biocides substituted tributyltin as an antifouling agent. It has continued to be used ever since, though little is known about their levels in the maritime setting of Zanzibar. This paper details the occurrence and distribution of diuron around the coastline of Zanzibar Island. The reported concentrations of diuron in water ranged from Below Detection Limit to 1321.67 ± 52.3 ng/L at Bwawani. Majority of the sites showed levels above Environmental Risk Limit of 430 ng/L as proposed by the Dutch Authorities. The findings suggest the contamination is elevated especial in Harbor, Bwawani, Chapwani and even at Marine Protected Areas such Mnemba Island where the value of 620.33 ± 5.70 ng/L was recorded. The main possible sources of the contamination are cargo shipping, passenger speedboats, fishing, and tourism activities taking places in these areas. Therefore, future studies on the antifouling biocide diuron particularly on long term monitoring, chronic exposure, risk assessment, organisms’ responses and pollution models will add special value towards better understanding of the mechanisms and sustainable marine ecosystem health.
文摘Research on habitat quality in ecologically vulnerable areas has gained attention due to mountain urbanization and climate change. However, the absence of comprehensive reviews limits a systematic understanding of habitat quality. This study investigates habitat quality research in ecologically vulnerable regions of China, drawing data from Web of Science and Scopus. Using CiteSpace software analyzes trends in publication volume, geographic distribution, journal outlets, research disciplines, and keyword co-occurrence. The findings identify two distinct research phases: an initial exploratory stage and a period of steady growth, with the Loess Plateau emerging as a primary focal region. Key journals, such as Ecological Indicators and Acta Ecologica Sinica, dominate the field, reflecting contributions from disciplines including environmental science and ecology. Research hotspots center on trade-offs between habitat quality and ecosystem services, driving factors of change, landscape pattern optimization, and simulation techniques. Future research should prioritize addressing the spatial heterogeneity of vulnerable regions, advancing methodological approaches, and enhancing uncertainty analyses in model parameterization. This study provides a critical foundation for addressing key scientific challenges and guiding future research, with implications for ecological security and sustainable development.
基金Supported by Guiding Project of Hebei Provincial Health Commission,No.20201190 and 20180220.
文摘BACKGROUND Effective health management for high-risk stroke populations is essential.The hospital-community-home(HCH)collaborative health management(CHM)model leverages resources from hospitals,communities,and families.By integrating patient information across these three domains,it facilitates the delivery of tailored guidance,health risk assessments,and three-in-one health education.AIM To explore the effects of the HCH-CHM model on stroke risk reduction in highrisk populations.METHODS In total,110 high-risk stroke patients screened in the community from January 2019 to January 2023 were enrolled,with 52 patients in the control group receiving routine health education and 58 in the observation group receiving HCH-CHM model interventions based on routine health education.Stroke awareness scores,health behavior levels,medication adherence,blood pressure,serum biochemical markers(systolic/diastolic blood pressure,total cholesterol,and triglyceride),and psychological measures(self-rating anxiety/depression scale)were evaluated and compared between groups.RESULTS The observation group showed statistically significant improvements in stroke awareness scores and health behavior levels compared to the control group(P<0.05),with notable enhancements in lifestyle and dietary habits(P<0.05)and reductions in postintervention systolic blood pressure,diastolic blood pressure,total cholesterol,triglyceride,self-rating anxiety scale,and self-rating depression scale scores(P<0.05).CONCLUSION The HCH-CHM model had a significant positive effect on high-risk stroke populations,effectively increasing disease awareness,improving health behavior and medication adherence,and appropriately ameliorating blood pressure,serum biochemical marker levels,and negative psychological symptoms.
基金Supported by Natural Science Foundation of Hubei Province,No.2023AFB848.
文摘BACKGROUND Inadequately controlled hypertension often leads to an increased cardiovascular death rate in type 2 diabetes mellitus(T2DM).It remains unclear whether systolic blood pressure(SBP)status of hypertension is related to coronary inflammation and plaques in T2DM.AIM To evaluate whether SBP variability(SBPV)and levels of hypertension are related to coronary inflammation and plaques in T2DM patients using coronary computed tomography angiography(CCTA).METHODS This retrospective study involved 881 T2DM patients with CCTA images,including 668 hypertension and 213 normotension patients.Hypertension patients were subgroup based on SBP status:(1)SBPV:Low(<8.96 mmHg)and high(≥8.96 mmHg)groups;and(2)SBP levels:Controlled(<140 mmHg)and uncontrolled(≥140 mmHg)groups.Pericoronary adipose tissue(PCAT)attenuation,high-risk plaques(HRPs)and obstructive stenosis(OS)were evaluated by CCTA.Propensity score matching was utilized to compare these CCTA findings for these groups.The impact of SBPV and SBP levels of hypertension on these CCTA findings in T2DM patients were evaluated by multivariate logistic regression and multivariable linear regression.RESULTS PCAT attenuation of the left anterior descending artery(LAD),any low attenuation plaque(LAP),any spotty calcification(SC),any positive remodeling(PR),and OS had significant differences between the hypertension group and the normotension group,as well as between the high SBPV or uncontrolled SBP group and the low SBPV or controlled SBP group(all P<0.05).Hypertension was independently positively correlated with LADPCAT attenuation(β=1.815,P=0.010),LAP(OR=1.612,P=0.019),SC(OR=1.665,P=0.013),PR(OR=1.549,P=0.033),and OS(OR=1.928,P=0.036)in all T2DM patients.Additionally,high SBPV and uncontrolled SBP were independently positively correlated with LAD-PCAT attenuation(high SBPV:β=1.673,P=0.048;uncontrolled SBP:β=2.370,P=0.004)and PR(high SBPV:OR=1.903,P=0.048;uncontrolled SBP:OR=2.230,P=0.013)in T2DM patients with hypertension.CONCLUSION Inadequately controlled hypertension,including high SBPV and/or uncontrolled SBP levels,may be related to increased coronary artery inflammation,HRPs,and OS in T2DM,leading to increased cardiovascular risk.Achieving both low SBPV and controlled SBP levels simultaneously,especially in individuals with T2DM and hypertension,warrants clinical attention.
基金supported by the National Natural Science Foun-dation of China(Grants No.42330103,42271469)the Ningbo Science and Technology Bureau(Grant No.2022Z081).
文摘The gap between the projected urban areas in the current trend(UAC)and those in the sustainable scenario(UAS)is a critical factor in understanding whether cities can fulfill the requirements of sustainable development.However,there is a paucity of knowledge on this cutting-edge topic.Given the extensive and rapid urbanization in the United States(U.S.)over the past two centuries,accurately measuring this gap between UAS and UAC is of critical importance for advancing future sustainable urban development,as well as having significant global implications.This study finds that although the 740 U.S.cities have a large UAC in 2100,these cities will encom pass a significant gap from UAC to UAS(approximately 165,000 km2),accounting for 30%UAC at that time.The study also reveals the spatio-temporal heterogeneity of the gap.The gap initially increases before reaching a inflection point in 2090,and it disparates greatly from−100%to 240%at city level.While cities in the Northwestern U.S.maintain UAC that exceeds UAS from 2020 to 2100,cities in other regions shift from UAC that exceeds UAS to UAC that falls short of UAS.Filling the gap without additional urban growth planning could lead to a reduction of crop production ranging from 0.3%to 3%and a 0.68%loss of biomass.Hence,dynamic and forward-looking urban planning is essential for addressing the challenges of sustainable development posed by urbanization,both within the U.S.and globally.
文摘In the context of rapid urbanization,cities must leverage their unique advantages to enhance their competitiveness.It has become a prevalent practice to integrate Chinese cultural elements into a city’s brand identity,as well as to transform and elevate the existing landscape.This paper examines the landscape evolution of Nanchang Bayi Park(Baihuazhou)and the associated measures for its transformation and enhancement.The findings indicate that,from the perspective of urban visual art,these transformations significantly enhance the city’s aesthetic perception and more effectively address the needs of people.Consequently,this contributes to the ongoing improvement and development of the city’s brand image.By modifying the urban structure,enhancing the urban environment,upgrading infrastructure,and elevating the cultural levels within urban areas,the objective of transforming and upgrading urban landscapes can be realized.
文摘Alkaline igneous rocks represent one of the most economically important resources of radioactive minerals and rare metals.New field observations and petrographic studies are integrated with whole-rock geochemical analyses and Gamma ray spectroscopy data of alkaline rocks associated with the Amreit complex.The fieldwork was achieved by the collection of more than forty samples from alkaline granites and alkaline syenites.The youngest rocks cropping out in the study area are the cogenetic alkaline rocks,ranging from alkaline granite to alkaline syenite.These alkaline rocks are composed essentially of K-feldspar,alkali amphiboles(arfvedsonite),and sodic pyroxene,with accessories such as zircon,apatite,and ilmenite.Mineral characterization of the highly radioactive zones in both alkaline granite and alkaline syenite displays enrichment in monazite,thorite,zircon,ferro-columbite,xenotime,and allanite minerals.Geochemical analyses indicate that the Amreit rocks are alkaline with peralkaline affinity and have high concentrations of total alkalis(K_(2)O+Na_(2)O),large ion lithophile elements(LILEs;Ba and Rb),high field strength elements(HFSEs;Y,Zr and Nb),rare earth elements(REEs)and significantly depleted in K,Sr,P,Ti,and Eu,typically of post-collision A-type granites.Typically,the Amreit alkaline igneous rocks are classified as within plate granites and display A2 subtype characteristics.The fractionation of K-feldspars played a distinctive role during the magmatic evolution of these alkaline rocks.The geochemical characteristics indicate that the studied alkaline igneous rocks which were originated by fractional crystallization of alkaline magmas were responsible for the enrichment of the REE and rare metals in the residual melt.The high radioactivity is essentially related to accessory minerals,such as zircon,allanite,and monazite.The alkaline granite is the most U-and Thrich rock,where radioactivity level reaches up to 14.7 ppm(181.55 Bq/kg)e U,40.6 ppm(164.84 Bq/kg)e Th,whereas in alkaline syenite radioactivity level is 8.5 ppm(104.96 Bq/kg)e U,30.2 ppm(122.61 Bq/kg)e Th.These observations suppose that these alkaline rocks may be important targets for REEs and radioactive mineral exploration.
文摘Background:Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. While liver transplantation (LT) provides the best long-term survival, it is constrained by organ scarcity and strict criteria. Liver resection (LR) is often the initial treatment for patients with solitary tumors and preserved liver function. The high recurrence rates associated with LR has prompted the exploration of sequential living donor liver transplantation (seq LDLT) after LR as a strategy for HCC patients with high-risk of recurrence.Methods:We analyzed data from 27 adult patients who underwent seq LDLT after LR for HCC at Kaohsiung Chang Gung Memorial Hospital (KCGMH) between June 1994 and December 2023. Patients were selected based on high-risk histopathological features post-LR or as part of downstaging strategy. Outcomes measured included overall survival (OS) and disease-free survival (DFS).Results:Among 765 HCC patients who underwent LDLT, 204 received LR before LDLT, and 27 underwent seqL DLT. Five patients (19%) underwent living donor liver transplantation (LDLT) following LR as a downstaging strategy while the rest received seqL DLT as a preemptive strategy. The median age was 53.5 years with 85%males. Chronic hepatitis B was the predominant underlying disease (74%). The 1-, 3-, and 5-year OS and DFS rates were 100%, 96.0%, 96.0%and 100%, 96.2%, 96.2%, respectively, with two patients experiencing HCC recurrence. One patient died from HCC recurrence. High-risk histopathological features included microvascular invasion (52%), satellite nodules (15%), multiple tumors (26%), tumors> 5 cm(19%), and a total tumor diameter> 10 cm (7%).Conclusions:Seq LDLT offers a promising, tailored approach for managing HCC with adverse histopathologic features. Combining seq LDLT, downstaging strategies, and multidisciplinary treatments can achieve satisfactory OS and DFS in carefully selected patients, highlighting the need for refined criteria to identify the best candidates.
基金funded by the National Key Research and De-velopment Program of China(Grant No.2023YFC3804001)the Natural Resources Planning and Management Project(Grant No.A2417,A2418)the Fundamental Scientific Research Funds for Central Public Wel-fare Research Institutes(Grant No.AR2409).
文摘Assessment of SDG11.3.1 indicator of the United Nations Sustainable Development Goals(SDGs)is a valuable tool for policymakers in urban planning.This study aims to enhance the accuracy of the SDG11.3.1 evaluation and explore the impact of varying precision levels in urban built-up area on the indicator’s assessment outcomes.We developed an algorithm to generate accurate urban built-up area data products based on China’s Geographical Condition Monitoring data with a 2 m resolution.The study evaluates urban land-use efficiency in China from 2015 to 2020 across different geographical units using both the research product and data derived from other studies utilizing medium and low-resolution imagery.The results indicate:(1)A significant improvement in the accuracy of our urban built-up area data,with the SDG11.3.1 evaluation results demonstrating a more precise reflection of spatiotemporal characteristics.The indicator shows a positive correlation with the accuracy level of the built-up area data;(2)From 2015 to 2020,Chinese prefecture-level cities have undergone faster urbanization in terms of land expansion relative to population growth,leading to less optimal land resource utilization.Only in extra-large cities does urban population growth show a relatively balanced pattern.However,urban popula tion growth in other regions and cities of various sizes lags behind land urbanization.Notably,Northeast China and small to medium cities encounter significant challenges in urban population growth.The comprehensive framework developed for evaluating SDG11.3.1 with high-precision urban built-up area data can be adapted to different national regions,yielding more accurate SDG11.3.1 outcomes.Our urban area and built-up area data products provide crucial inputs for calculating at least four indicators related to SDG11.
基金Collaborative Project Grant from the Exploration and Development Research Institute of SINOPEC Northwest Oilfi eld Company(Grant No.KY2021-S-104).
文摘The Tarim Basin has revealed numerous tight sandstone oil and gas reservoirs.The tidal fl at zone in the Shunbei area is currently in the detailed exploration stage,requiring a comprehensive description of the sand body distribution characteristics for rational exploration well deployment.However,using a single method for sand body prediction has yielded poor results.Seismic facies analysis can eff ectively predict the macro-development characteristics of sedimentary sand bodies but lacks the resolution to capture fi ne details.In contrast,single-well sedimentary facies analysis can describe detailed sand body development but struggles to reveal broader trends.Therefore,this study proposes a method that combines seismic facies analysis with single-well sedimentary microfacies analysis,using the lower section of the Kepingtage Formation in the Shunbei area as a case study.First,seismic facies were obtained through unsupervised vector quantization to control the macro-distribution characteristics of sand bodies,while principal component analysis(PCA)was applied to improve the depiction of fi ne sand body details from seismic attributes.Based on 3D seismic data,well-logging data,and geological interpretation results,a detailed structural interpretation was performed to establish a high-precision stratigraphic framework,thereby enhancing the accuracy of sand body prediction.Seismic facies analysis was then conducted to obtain the macro-distribution characteristics of the sand bodies.Subsequently,core data and logging curves from individual wells were used to clarify the vertical development characteristics of tidal channels and sandbars.Next,PCA was employed to select the seismic attributes most sensitive to sand bodies in diff erent sedimentary facies.Results indicate that RMS amplitude in the subtidal zone and instantaneous phase in the intertidal zone are the most sensitive to sand bodies.A comparative analysis of individual seismic attributes for sand body characterization revealed that facies-based delineation improved the accuracy of sand body identifi cation,eff ectively capturing their contours and shapes.This method,which integrates seismic facies,single-well sedimentary microfacies,and machine learning techniques,enhances the precision of sand body characterization and off ers a novel approach to sand body prediction.
基金The research project is funded by the Geological Joint Fund(U2244209).
文摘The Majiagou Formation in the Fuxian area of the southeastern Ordos Basin has undergone a complex diagenetic evolution history under the influence of eustacy and the Caledonian karstification,resulting in several complex reservoir types.Through analyses of mineralogy,petrology,and reservoir geology,three major types of dolomite reservoirs with different genetic mechanisms,including anhydritic moldicdissolved pore type,dolomitic intercrystalline-pore type,and fractured type were identified,and their formation mechanisms and distribution patterns were examined.The aphanocrystalline to very finecrystalline anhydritic dolomite was resulted from Sabhak dolomitization,and is characterized by small size of crystals and high content of anhydrite.Dolomite reservoirs of anhydritic moldic-dissolved pore type were developed in multi-stage dissolution processes and mainly distributed at higher positions of the paleogeomorphology where the filling was weak.The very fine to fine-crystalline dolomite of shoal facies was formed under seepage-reflux dolomitization,and characterized by larger sizes of crystals and well-developed intercrystalline pores.Dolomite reservoirs of intercrystalline-pore type were mainly developed at the lower positions of the paleogeomorphology where bedding-parallel karst dissolution was strong.The fractured dolomite reservoirs,generated by the anhydrite swelling and karst cave collapse,occur in multiple horizons but within limited areas due to multi-stage fillings.
基金Open access funding provided by University of Natural Resources and Life Sciences Vienna(BOKU).
文摘This paper presents a standardised workflow for conducting hazard assessments of mass wasting processes in remote mountain areas with limited data.The methodology integrates geomorphological mapping and remote sensing techniques and is adaptable to different national standards,thus ensuring its applicability in a variety of contexts.The principal objective is to guarantee the safety of mountainous regions,particularly in the vicinity of essential infrastructure,where the scope for implementing structural measures is restricted.The framework commences with comprehensive geomorphological mapping,which facilitates the identification of past hazardous processes and potential future hazards.New technologies,such as uncrewed aerial vehicles(UAVs),are employed to create high-resolution DEMs,which are particularly beneficial in regions with limited data availability.These models facilitate the assessment of potential hazards and inform decisions regarding protective measures.The utilisation of UAVs enhances the accuracy and efficiency of data collection,particularly in remote mountainous regions where alternative remotely sensed information may be unavailable.The integration of modern approaches into traditional hazard assessment methods allows for a comprehensive analysis of the spatial distribution of factors driving mass wasting processes.This workflow provides valuable insights that assist in the prioritisation of interventions and the optimisation of risk reduction in high mountainous areas.
基金National Natural Science Foundation of china(Grant No.12402468)。
文摘RBOE is a new type of DNAN-based high-energy melt-cast mixed explosive,whose safety under thermal stimulation is significantly affected by heating conditions and venting area of the warhead.Based on the thermal decomposition reaction characteristics and combustion characteristics of each component of RBOE explosive,the cook-off calculation models of RBOE warhead before and after ignition were established.In addition,closed and vented warheads were designed,as well as fast and slow cook-off test devices.The cook-off characteristics and thermal safety venting area of RBOE warhead were extensively studied.The results showed that the closed RBOE warhead underwent deflagration reaction under both slow and fast cook-off conditions.The calculation result of the shell wall temperature before slow cookoff ignition response of the warhead was 454.06 K,with an error of+1.75%compared to the test result of462.15 K,and the temperature rise rate calculated was in good agreement with the test.The calculated ignition time of RBOE warhead under fast cook-off was 161 s,with an error of+8.8%compared to the test result of 148 s,which verified the accuracy of cook-off model of RBOE warhead before ignition.According to the cook-off calculation model of the warhead after ignition and cook-off test of the vented warhead,it was determined that the thermal safety venting area was 1124.61 mm^(2)for fast cook-off and 530.66 mm~2 for slow cook-off,effectively preventing the reaction of warhead above combustion.Therefore,this study provides a scientific basis for the thermal safety design and evaluation of insensitive warheads.
基金The financial support by the Deutsche Bundesstiftung Umwelt (DBU)
文摘Deforestation remains one of the most imminent threats to biodiversity in the tropics.As such,its causes and dynamics need to be studied and understood to put a halt to further forest loss and degradation.In tropical countries such as Uganda,agricultural expansion and wood fuel demand are its leading drivers.While the establishment of protected areas is a key tool in conserving remaining forest biodiversity,results indicate that current management does not sufficiently provide alternatives to forest resources utilised by households and income provided from timber and non-timber forest products.Beyond safeguarding ecosystems,protected areas need to ensure the sustainable socioeconomic development of adjacent communities for effective biodiversity conservation–however,both management and research often neglect to consider all dimensions.In this study,we analysed five decades of forest cover change in the Mount Elgon region,Uganda,by conducting a remote sensing analysis of its protected areas using Landsat MSS and TM data from 1973-2023 in combination with literature and subsequent interview analysis to consider both the ecological and socioeconomic dimension.We applied a random forest approach to differentiate forest and non-forest areas and carried out a pixel-based change detection analysis to differentiate temporal and spatial changes.Throughout the study period of 50 years,forest cover has evolved dynamically within the boundaries of the protected areas of Mount Elgon.A significant decline was observed in both Mount Elgon National Park with a loss of-5.98%(-46.83km²)and Mount Elgon Biosphere Reserve with a loss of-14.96%(-134.33km²).Our results showcase a cycle of deforestation and afforestation that could be tied to a series of development initiatives,re-demarcation of boundaries,changes in management and recurring evictions.Overall,the results lead to the conclusion that the lack of sustainable and efficient management and funding has fostered the rate of deforestation and accelerated ecological degradation in the region,but that existing problems are also rooted in the land tenure history of the region.We recommend the proper implementation of participatory and long-term management approaches on the ground and to address the land rights issue to contribute to both socioeconomic wellbeing and sustainable conservation outcomes.