To characterize long-term nonprogressors （LTNPs） and viremia controllers （VCs）, infected with HIV-1 through contaminated blood donation or transfusion between 1992 and 1996 in Henan, China. LTNPs and VCs were defi...To characterize long-term nonprogressors （LTNPs） and viremia controllers （VCs）, infected with HIV-1 through contaminated blood donation or transfusion between 1992 and 1996 in Henan, China. LTNPs and VCs were defined by CD4＋T lymphocyte （CD4） count and viral load （VL）. Of 29,294 patients infected with HIV-1 via contaminated blood donation or transfusion that had conducted for more than 20 years, 92 were LTNPs/VCs. There were 70 LTNPs （0.24%）, 43 VCs （0.15%）, and 48 LTNPs＋VCs- （0.16%）.展开更多
One big achievement in the last decade is the rapid development in transplantation medicine, enabling seriously ill people to live longer. However, in the year 2014, 12 people in the European Union have died every day...One big achievement in the last decade is the rapid development in transplantation medicine, enabling seriously ill people to live longer. However, in the year 2014, 12 people in the European Union have died every day because of the lack of available organs. Nearly, 70,000 people were waiting for a matching graft. An analysis of donation and transplantation variation across the European member states shows that since many years, Spain occupies a pioneer role, whereas Germany and Austria are lagging behind. From the legal and administrative perspective, Spain and Austria are quite similar with their presumed consent system （opting out）, whereas Germany has an informed consent system （opting in）. Hence, there must be other influencing factors like the way of multilevel communication leading to the following research question： How does multilevel communication influence organ donations in Spain, Germany, and Austria？ On the basis of a cross-country study, it can be shown that strategic communication on the （inter）personal and organizational level supported by the creation of public awareness on the national level is crucial for succeeding in closing the gap between demands and realized organ transplantation.展开更多
Having a large number of timely donations during the early stages of a COVID-19 breakout would normally be considered rare. Donation is a special public goods game with zero yield for donors, and it has the characteri...Having a large number of timely donations during the early stages of a COVID-19 breakout would normally be considered rare. Donation is a special public goods game with zero yield for donors, and it has the characteristics of the prisoners’ dilemma. This paper discusses why timely donations in the early stages of COVID-19 occurred. Based on the idea that donation is a strategy adopted by players during interconnection on account of their understanding of the environment, donation-related populations are placed on social networks and the inter-correlation structures in the population are described by scale-free networks. Players in donation-related populations are of four types: donors, illegal beneficiaries,legal beneficiaries, and inactive people. We model the evolutionary game of donation on a scale-free network. Donors,illegal beneficiaries and inactive people learn and update strategies under the Fermi update rule, whereas the conversion between legal beneficiaries and the other three types is determined by the environment surrounding the players. We study the evolution of cooperative action when the agglomeration coefficient, the parameters of the utility function, the noise intensity, the utility coefficient, the donation coefficient and the initial states of the population on the scale-free network change. For population sizes of 50, 100, 150, and 200, we give the utility functions and the agglomeration coefficients for promoting cooperation and study the corresponding steady states and structural characteristics of the population. We identify the best ranges of the noise intensity K, the donation coefficient α and the utility coefficient β for promoting cooperation at different population sizes. Furthermore, with the increase of the population size, the donor traps are found.At the same time, it is discovered that the initial states of the population have a great impact on the steady states;thus the upper and lower triangle phenomena are proposed. We also find that the population size itself is also an important factor for promoting donation, pointing out the direction of efforts to further promote donation and achieve better social homeostasis under the donation model.展开更多
Over half of the forestland in the United States is in private hands. Just over 10 million individual and family owners control about 60% of this private forestland. Ownership of family forests changes on a regular ba...Over half of the forestland in the United States is in private hands. Just over 10 million individual and family owners control about 60% of this private forestland. Ownership of family forests changes on a regular basis;sometimes from generation to generation and sometimes to outside of the family. Often new owners are not interested in forest management and sell off the asset. Some owners attempt to ensure their family forest remains pristine and undeveloped. This is leading to timberland donations to entities that can be expected to hold the donated forest permanently and ensure sustainable forest management. University foundations and forestry schools are increasingly receiving timberland as donations. It is a way for donors to monetize the asset (with tax breaks) and protect it at the same time. Foundations have a problem with timberland as they often don’t fully understand it as an investment. Certainly there are even times when a foundation should not accept it as a donation. The nature of timberland as an investment is explained, along with basic terminology that is common use. Age class distribution and the resulting cash flow dis- tribution is explained, as well as timber volume, harvest scheduling, timberland investment analysis, tim- ber value, timber sales, and timber contracts. All of these are tools foundation board members need to evaluate timberland donations.展开更多
Deceased organ donation is much less prominent in Japan than it is in Western and other Asian countries. Because a shortage of organ donation is a serious social issue in Japan, various solutions to the issue have bee...Deceased organ donation is much less prominent in Japan than it is in Western and other Asian countries. Because a shortage of organ donation is a serious social issue in Japan, various solutions to the issue have been considered. Although it was believed that the most critical factor in the organ shortage was the absence of a well-established social system, no prior studies attempted to analyze the issue from the perspective of the mechanisms and organizational behaviors. To identify common success factors of increasing organ donation, we conducted a qualitative survey in 5 countries promoting organ donations on a national level and increasing the number of organ donations. We found several important common factors: 1) to change from an explicit consent system to a presumed consent system with establishment of an appropriate in-hospital system, 2) to increase the level of job satisfaction of healthcare professionals and help them generating better results, 3) to demonstrate managements’ leadership for all staff to realize the importance of organ donations, 4) to establish an environment where medical professionals engaged in organ donations can appreciate autonomous working styles, the recognition of the importance of the work. It is suggested that these successful factors are introduced into Japan with long-, mid-term strategy to enhance organ donation.展开更多
Although national transplant organizations share common visions and goals,the creation of a unified global organization remains impractical.Differences in ethnicity,culture,religion,and education shape local practices...Although national transplant organizations share common visions and goals,the creation of a unified global organization remains impractical.Differences in ethnicity,culture,religion,and education shape local practices and infrastructure,making the establishment of a single global entity unfeasible.Even with these social disparities aside,logistical factors such as time and distance between organ procurement and transplantation sites pose significant challenges.While technological advancements have extended organ preservation times,they have yet to support the demands of transcontinental transplantations effectively.This review presents a comparative analysis of the structures,operational frameworks,policies,and legislation governing various transplant organizations around the world.Key differences pertain to the administration of these organizations,trends in organ donation,and organ allocation policies,which reflect the financial,cultural,and religious diversity across different regions.While a global transplant organization may be out of reach,agreeing on best practices for the benefit of patients is essential.展开更多
The relationship between air pollution and charitable donations of companies has received little attention from academia.To make up for this defect,we use a regression discontinuity design based on the spatial discont...The relationship between air pollution and charitable donations of companies has received little attention from academia.To make up for this defect,we use a regression discontinuity design based on the spatial discontinuity in air pollution created by China's winter heating policy in the north of Qinling Mountains–Huai River line to examine whether severe air pollution may cause polluting companies to make charitable donations.Our results consistently show that air pollution has a positive impact on the donations of polluting companies,regardless of whether the absolute donations,the relative donations,or the willingness to donate are used to measure donations.A series of robustness tests confirm that this relationship is causal.Furthermore,we find that under severe air pollution,the motivations of polluting companies to implement donation behaviors are to decrease the probability of environmental penalties,reduce environmental pollution costs,and decrease the extent to which air pollution affects company reputations.展开更多
The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established b...The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established by the World Health Organization(WHO). Reform in China has demonstrated the unwavering confidence and utmost determination of the Chinese government and the Chinese transplantation community. The year 2015 marked a historic turning point when voluntary donations from Chinese citizens became the sole legitimate source for organ transplantation. Since 2015, China has gradually established and refined the “Chinese Mode” and “China System” for organ donation and transplantation, fulfilling its political pledge of reform, and has garnered international recognition, and fostered a social culture which promotes organ donation. This article reviewed the history of reform on organ donation and transplantation in China, presented a new pattern of establishment of organ donation system in the new era of the country, and the direction of advances in the future.展开更多
On June 21, at the inauguration of the Beijing Normal University One Foundation Philanthropy Research Institute, Wang Zhenyao, the institute’s Dean and former Director of the Social Welfare and
This paper explores how the influences corporate donations, based on political identity of top managers upper echelons theory （UET）. The results show that the political identity of the top manager has a significant ...This paper explores how the influences corporate donations, based on political identity of top managers upper echelons theory （UET）. The results show that the political identity of the top manager has a significant impact on the donation behavior of a company, especially in areas with poor institutional environments. Corporate donations depend not only on whether the top manager has a political identity but also the type of this identity. Furthermore, the impact differs significantly between companies with different ownership structures. This study enriches our knowledge of corporate philanthropy by demonstrating that corporate donation practices are shaped by a range of contextual factors. Corporate giving behaviors in emerging economies such as China are differently motivated according to the fundamentally different aspects of their institutional settings.展开更多
The commonly held belief among most people is that acts of charity are carried out with no thought of getting something in return, or of attaching conditions to those who receive donations. It’s perhaps for this r...The commonly held belief among most people is that acts of charity are carried out with no thought of getting something in return, or of attaching conditions to those who receive donations. It’s perhaps for this rea- son that events surrounding the Henan Charity Federation’s recent decision to add an agenda to students’ financial aid caused such a public outcry.展开更多
The dust is slowly settling after the Sichuan quake and as restructuring work gets into full swing,the billions of yuan in donations is slowly finding their way to the
According to the risk management and reputation insurance theory of corporate social responsibility, corporate donations can help a company to repair its reputation after a crisis.This study uses a propensity score ma...According to the risk management and reputation insurance theory of corporate social responsibility, corporate donations can help a company to repair its reputation after a crisis.This study uses a propensity score matching–difference in difference(PSM + DID) methodology to investigate the charitable donation activities of companies that have been subject to regulatory penalties.The analysis of a sample of A-share listed companies in the 2004–2016 period shows that companies significantly increase their charitable donations after regulatory penalties, but this effect weakens over time.Further analysis reveals that non-state-owned companies, companies with higher ownership concentrations, and companies receiving severer penalties are more motivated to make donations after regulatory penalties.By studying the reputation repair behavior of companies that have been subject to regulatory penalties, this study offers further support for the risk management and reputation insurance theory of corporate social responsibility.It also enriches our understanding of companies’ active responses to regulatory penalties and provides insights into companies’ motives for making charitable donations.展开更多
Objective:To assess the attitude and willingness of medical students of the Faculty of Medicine,University of Jaffna,regarding gamete donation.Methods:An institutional-based descriptive cross-sectional study was condu...Objective:To assess the attitude and willingness of medical students of the Faculty of Medicine,University of Jaffna,regarding gamete donation.Methods:An institutional-based descriptive cross-sectional study was conducted at the Faculty of Medicine,University of Jaffna,from September 2022 to May 2023 among undergraduate medical students who gave their voluntary participation.A self-administered questionnaire was used as a study instrument to collect data regarding their attitude and willingness toward gamete donation.Results:A total of 345 participants were recruited and their sociodemographic data revealed that 56.8%of the participants were female,62.3%aged between 26 and 30 years,and 92.2%were unmarried.Many of them received information regarding gamete donations during their clinical appointments.Over half(67.8%)of them showed a negative attitude towards gamete donation.Regarding willingness,only 39.7%of participants had a positive approach for being a gamete donor;among them,84.7%preferred anonymous donations.Religion and ethnicity had a significant influence on their attitudes and willingness.In addition,male was also found to be more willing to donate gametes.Conclusions:Most medical students have negative views about gamete donation.Imparting awareness and knowledge of assisted reproductive technology and gamete donation within medical students'sociocultural and ethical backgrounds might facilitate a change in attitude towards gamete donation amongst future medical practitioners.展开更多
The standard approach to organ preservation in liver transplantation is by static cold storage and the time between the cross-clamping of a graft in a donor and its reperfusion in the recipient is defined as cold isch...The standard approach to organ preservation in liver transplantation is by static cold storage and the time between the cross-clamping of a graft in a donor and its reperfusion in the recipient is defined as cold ischemia time(CIT).This simple definition reveals a multifactorial time frame that depends on donor hepatectomy time,transit time,and recipient surgery time,and is one of the most important donor-related risk factors which may influence the graft and recipient’s survival.Recently,the growing demand for the use of marginal liver grafts has prompted scientific exploration to analyze ischemia time factors and develop different organ preservation strategies.This review details the CIT definition and analyzes its different factors.It also explores the most recent strategies developed to implement each timestamp of CIT and to protect the graft from ischemic injury.展开更多
There is shortage of organs,including kidneys,worldwide.Along with deceased kidney transplantation,there is a significant rise in live kidney donation.The prevalence of prediabetes(PD),including impaired fasting gluco...There is shortage of organs,including kidneys,worldwide.Along with deceased kidney transplantation,there is a significant rise in live kidney donation.The prevalence of prediabetes(PD),including impaired fasting glucose and impaired glucose tolerance,is on the rise across the globe.Transplant teams frequently come across prediabetic kidney donors for evaluation.Prediabetics are at risk of diabetes,chronic kidney disease,cardiovascular events,stroke,neuropathy,retinopathy,dementia,depression and nonalcoholic liver disease along with increased risk of all-cause mortality.Unfortunately,most of the studies done in prediabetic kidney donors are retrospective in nature and have a short follow up period.There is lack of prospective long-term studies to know about the real risk of complications after donation.Furthermore,there are variations in recommendations from various guidelines across the globe for donations in prediabetics,leading to more confusion among clinicians.This increases the responsibility of transplant teams to take appropriate decisions in the best interest of both donors and recipients.This review focuses on pathophysiological changes of PD in kidneys,potential complications of PD,other risk factors for development of type 2 diabetes,a review of guidelines for kidney donation,the potential role of diabetes risk score and calculator in kidney donors and the way forward for the evaluation and selection of prediabetic kidney donors.展开更多
This article provides a concise overview of the development of organ transplantation in China.Inspired by international advancements in organ transplantation,China embarked on its own organ transplantation research jo...This article provides a concise overview of the development of organ transplantation in China.Inspired by international advancements in organ transplantation,China embarked on its own organ transplantation research journey in 1958.The clinical evaluation phase is marked by the first cadaveric kidney transplant in 1960 and the first living-donor kidney transplant in 1972.By 1989,the annual number of successful kidney transplants had surpassed 1000.However,57 liver transplants were performed between 1977 and 1983;limitations in technology and the scarcity of cyclosporine A resulted in unfavorable outcomes for most recipients,with the majority succumbing within 3 months of surgery.These factors led to a near-complete halt in liver,heart,and lung transplants for the following decade.With all 4 conditions met-(1)mature surgical techniques,(2)powerful immunosuppressive agents available for clinical use,(3)new organ preservation solutions that ensure the quality and transportation of donor organs,and(4)reasonable and legal sources of organs-China's organ transplantation field has experienced rapid development.In 2014,there were 9652 organ transplants,and this number grew to 20,225 by 2022.Despite the progress,China's organ donation rate per million remains relatively low,3.86 ranking 48th globally in 2022,underscoring the need for increased public awareness and support for organ donation.展开更多
基金supported by grants from The National Key Science and Technology Projects on Major Infectious Disease Grant[2012ZX10001‐002 and 2017ZX10105009]Key Projects for Science and Technology Development of Henan Province[142102310076 and 162300410123]
文摘To characterize long-term nonprogressors （LTNPs） and viremia controllers （VCs）, infected with HIV-1 through contaminated blood donation or transfusion between 1992 and 1996 in Henan, China. LTNPs and VCs were defined by CD4＋T lymphocyte （CD4） count and viral load （VL）. Of 29,294 patients infected with HIV-1 via contaminated blood donation or transfusion that had conducted for more than 20 years, 92 were LTNPs/VCs. There were 70 LTNPs （0.24%）, 43 VCs （0.15%）, and 48 LTNPs＋VCs- （0.16%）.
文摘One big achievement in the last decade is the rapid development in transplantation medicine, enabling seriously ill people to live longer. However, in the year 2014, 12 people in the European Union have died every day because of the lack of available organs. Nearly, 70,000 people were waiting for a matching graft. An analysis of donation and transplantation variation across the European member states shows that since many years, Spain occupies a pioneer role, whereas Germany and Austria are lagging behind. From the legal and administrative perspective, Spain and Austria are quite similar with their presumed consent system （opting out）, whereas Germany has an informed consent system （opting in）. Hence, there must be other influencing factors like the way of multilevel communication leading to the following research question： How does multilevel communication influence organ donations in Spain, Germany, and Austria？ On the basis of a cross-country study, it can be shown that strategic communication on the （inter）personal and organizational level supported by the creation of public awareness on the national level is crucial for succeeding in closing the gap between demands and realized organ transplantation.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.72031009 and 71871171)the National Social Science Foundation of China(Grant No.20&ZD058)。
文摘Having a large number of timely donations during the early stages of a COVID-19 breakout would normally be considered rare. Donation is a special public goods game with zero yield for donors, and it has the characteristics of the prisoners’ dilemma. This paper discusses why timely donations in the early stages of COVID-19 occurred. Based on the idea that donation is a strategy adopted by players during interconnection on account of their understanding of the environment, donation-related populations are placed on social networks and the inter-correlation structures in the population are described by scale-free networks. Players in donation-related populations are of four types: donors, illegal beneficiaries,legal beneficiaries, and inactive people. We model the evolutionary game of donation on a scale-free network. Donors,illegal beneficiaries and inactive people learn and update strategies under the Fermi update rule, whereas the conversion between legal beneficiaries and the other three types is determined by the environment surrounding the players. We study the evolution of cooperative action when the agglomeration coefficient, the parameters of the utility function, the noise intensity, the utility coefficient, the donation coefficient and the initial states of the population on the scale-free network change. For population sizes of 50, 100, 150, and 200, we give the utility functions and the agglomeration coefficients for promoting cooperation and study the corresponding steady states and structural characteristics of the population. We identify the best ranges of the noise intensity K, the donation coefficient α and the utility coefficient β for promoting cooperation at different population sizes. Furthermore, with the increase of the population size, the donor traps are found.At the same time, it is discovered that the initial states of the population have a great impact on the steady states;thus the upper and lower triangle phenomena are proposed. We also find that the population size itself is also an important factor for promoting donation, pointing out the direction of efforts to further promote donation and achieve better social homeostasis under the donation model.
文摘Over half of the forestland in the United States is in private hands. Just over 10 million individual and family owners control about 60% of this private forestland. Ownership of family forests changes on a regular basis;sometimes from generation to generation and sometimes to outside of the family. Often new owners are not interested in forest management and sell off the asset. Some owners attempt to ensure their family forest remains pristine and undeveloped. This is leading to timberland donations to entities that can be expected to hold the donated forest permanently and ensure sustainable forest management. University foundations and forestry schools are increasingly receiving timberland as donations. It is a way for donors to monetize the asset (with tax breaks) and protect it at the same time. Foundations have a problem with timberland as they often don’t fully understand it as an investment. Certainly there are even times when a foundation should not accept it as a donation. The nature of timberland as an investment is explained, along with basic terminology that is common use. Age class distribution and the resulting cash flow dis- tribution is explained, as well as timber volume, harvest scheduling, timberland investment analysis, tim- ber value, timber sales, and timber contracts. All of these are tools foundation board members need to evaluate timberland donations.
文摘Deceased organ donation is much less prominent in Japan than it is in Western and other Asian countries. Because a shortage of organ donation is a serious social issue in Japan, various solutions to the issue have been considered. Although it was believed that the most critical factor in the organ shortage was the absence of a well-established social system, no prior studies attempted to analyze the issue from the perspective of the mechanisms and organizational behaviors. To identify common success factors of increasing organ donation, we conducted a qualitative survey in 5 countries promoting organ donations on a national level and increasing the number of organ donations. We found several important common factors: 1) to change from an explicit consent system to a presumed consent system with establishment of an appropriate in-hospital system, 2) to increase the level of job satisfaction of healthcare professionals and help them generating better results, 3) to demonstrate managements’ leadership for all staff to realize the importance of organ donations, 4) to establish an environment where medical professionals engaged in organ donations can appreciate autonomous working styles, the recognition of the importance of the work. It is suggested that these successful factors are introduced into Japan with long-, mid-term strategy to enhance organ donation.
文摘Although national transplant organizations share common visions and goals,the creation of a unified global organization remains impractical.Differences in ethnicity,culture,religion,and education shape local practices and infrastructure,making the establishment of a single global entity unfeasible.Even with these social disparities aside,logistical factors such as time and distance between organ procurement and transplantation sites pose significant challenges.While technological advancements have extended organ preservation times,they have yet to support the demands of transcontinental transplantations effectively.This review presents a comparative analysis of the structures,operational frameworks,policies,and legislation governing various transplant organizations around the world.Key differences pertain to the administration of these organizations,trends in organ donation,and organ allocation policies,which reflect the financial,cultural,and religious diversity across different regions.While a global transplant organization may be out of reach,agreeing on best practices for the benefit of patients is essential.
基金supported by the National Natural Science Foundation of China (No.72203180)Huazhong University of Science and Technology Double First-class Funds for Humanities and Social Sciences。
文摘The relationship between air pollution and charitable donations of companies has received little attention from academia.To make up for this defect,we use a regression discontinuity design based on the spatial discontinuity in air pollution created by China's winter heating policy in the north of Qinling Mountains–Huai River line to examine whether severe air pollution may cause polluting companies to make charitable donations.Our results consistently show that air pollution has a positive impact on the donations of polluting companies,regardless of whether the absolute donations,the relative donations,or the willingness to donate are used to measure donations.A series of robustness tests confirm that this relationship is causal.Furthermore,we find that under severe air pollution,the motivations of polluting companies to implement donation behaviors are to decrease the probability of environmental penalties,reduce environmental pollution costs,and decrease the extent to which air pollution affects company reputations.
文摘The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established by the World Health Organization(WHO). Reform in China has demonstrated the unwavering confidence and utmost determination of the Chinese government and the Chinese transplantation community. The year 2015 marked a historic turning point when voluntary donations from Chinese citizens became the sole legitimate source for organ transplantation. Since 2015, China has gradually established and refined the “Chinese Mode” and “China System” for organ donation and transplantation, fulfilling its political pledge of reform, and has garnered international recognition, and fostered a social culture which promotes organ donation. This article reviewed the history of reform on organ donation and transplantation in China, presented a new pattern of establishment of organ donation system in the new era of the country, and the direction of advances in the future.
文摘On June 21, at the inauguration of the Beijing Normal University One Foundation Philanthropy Research Institute, Wang Zhenyao, the institute’s Dean and former Director of the Social Welfare and
基金Acknowledgements We thank the editor and two anonymous reviewers for their many insightful and constructive suggestions. This work was supported by the National Natural Science Foundation of China （71372166, 71502174） and the Research Base on Low-carbon Economy for Guangzhou Area.
文摘This paper explores how the influences corporate donations, based on political identity of top managers upper echelons theory （UET）. The results show that the political identity of the top manager has a significant impact on the donation behavior of a company, especially in areas with poor institutional environments. Corporate donations depend not only on whether the top manager has a political identity but also the type of this identity. Furthermore, the impact differs significantly between companies with different ownership structures. This study enriches our knowledge of corporate philanthropy by demonstrating that corporate donation practices are shaped by a range of contextual factors. Corporate giving behaviors in emerging economies such as China are differently motivated according to the fundamentally different aspects of their institutional settings.
文摘The commonly held belief among most people is that acts of charity are carried out with no thought of getting something in return, or of attaching conditions to those who receive donations. It’s perhaps for this rea- son that events surrounding the Henan Charity Federation’s recent decision to add an agenda to students’ financial aid caused such a public outcry.
文摘The dust is slowly settling after the Sichuan quake and as restructuring work gets into full swing,the billions of yuan in donations is slowly finding their way to the
基金financial support from the China National Social Science Foundation Key Research Project (Project No.17ZDA086)
文摘According to the risk management and reputation insurance theory of corporate social responsibility, corporate donations can help a company to repair its reputation after a crisis.This study uses a propensity score matching–difference in difference(PSM + DID) methodology to investigate the charitable donation activities of companies that have been subject to regulatory penalties.The analysis of a sample of A-share listed companies in the 2004–2016 period shows that companies significantly increase their charitable donations after regulatory penalties, but this effect weakens over time.Further analysis reveals that non-state-owned companies, companies with higher ownership concentrations, and companies receiving severer penalties are more motivated to make donations after regulatory penalties.By studying the reputation repair behavior of companies that have been subject to regulatory penalties, this study offers further support for the risk management and reputation insurance theory of corporate social responsibility.It also enriches our understanding of companies’ active responses to regulatory penalties and provides insights into companies’ motives for making charitable donations.
文摘Objective:To assess the attitude and willingness of medical students of the Faculty of Medicine,University of Jaffna,regarding gamete donation.Methods:An institutional-based descriptive cross-sectional study was conducted at the Faculty of Medicine,University of Jaffna,from September 2022 to May 2023 among undergraduate medical students who gave their voluntary participation.A self-administered questionnaire was used as a study instrument to collect data regarding their attitude and willingness toward gamete donation.Results:A total of 345 participants were recruited and their sociodemographic data revealed that 56.8%of the participants were female,62.3%aged between 26 and 30 years,and 92.2%were unmarried.Many of them received information regarding gamete donations during their clinical appointments.Over half(67.8%)of them showed a negative attitude towards gamete donation.Regarding willingness,only 39.7%of participants had a positive approach for being a gamete donor;among them,84.7%preferred anonymous donations.Religion and ethnicity had a significant influence on their attitudes and willingness.In addition,male was also found to be more willing to donate gametes.Conclusions:Most medical students have negative views about gamete donation.Imparting awareness and knowledge of assisted reproductive technology and gamete donation within medical students'sociocultural and ethical backgrounds might facilitate a change in attitude towards gamete donation amongst future medical practitioners.
文摘The standard approach to organ preservation in liver transplantation is by static cold storage and the time between the cross-clamping of a graft in a donor and its reperfusion in the recipient is defined as cold ischemia time(CIT).This simple definition reveals a multifactorial time frame that depends on donor hepatectomy time,transit time,and recipient surgery time,and is one of the most important donor-related risk factors which may influence the graft and recipient’s survival.Recently,the growing demand for the use of marginal liver grafts has prompted scientific exploration to analyze ischemia time factors and develop different organ preservation strategies.This review details the CIT definition and analyzes its different factors.It also explores the most recent strategies developed to implement each timestamp of CIT and to protect the graft from ischemic injury.
文摘There is shortage of organs,including kidneys,worldwide.Along with deceased kidney transplantation,there is a significant rise in live kidney donation.The prevalence of prediabetes(PD),including impaired fasting glucose and impaired glucose tolerance,is on the rise across the globe.Transplant teams frequently come across prediabetic kidney donors for evaluation.Prediabetics are at risk of diabetes,chronic kidney disease,cardiovascular events,stroke,neuropathy,retinopathy,dementia,depression and nonalcoholic liver disease along with increased risk of all-cause mortality.Unfortunately,most of the studies done in prediabetic kidney donors are retrospective in nature and have a short follow up period.There is lack of prospective long-term studies to know about the real risk of complications after donation.Furthermore,there are variations in recommendations from various guidelines across the globe for donations in prediabetics,leading to more confusion among clinicians.This increases the responsibility of transplant teams to take appropriate decisions in the best interest of both donors and recipients.This review focuses on pathophysiological changes of PD in kidneys,potential complications of PD,other risk factors for development of type 2 diabetes,a review of guidelines for kidney donation,the potential role of diabetes risk score and calculator in kidney donors and the way forward for the evaluation and selection of prediabetic kidney donors.
文摘This article provides a concise overview of the development of organ transplantation in China.Inspired by international advancements in organ transplantation,China embarked on its own organ transplantation research journey in 1958.The clinical evaluation phase is marked by the first cadaveric kidney transplant in 1960 and the first living-donor kidney transplant in 1972.By 1989,the annual number of successful kidney transplants had surpassed 1000.However,57 liver transplants were performed between 1977 and 1983;limitations in technology and the scarcity of cyclosporine A resulted in unfavorable outcomes for most recipients,with the majority succumbing within 3 months of surgery.These factors led to a near-complete halt in liver,heart,and lung transplants for the following decade.With all 4 conditions met-(1)mature surgical techniques,(2)powerful immunosuppressive agents available for clinical use,(3)new organ preservation solutions that ensure the quality and transportation of donor organs,and(4)reasonable and legal sources of organs-China's organ transplantation field has experienced rapid development.In 2014,there were 9652 organ transplants,and this number grew to 20,225 by 2022.Despite the progress,China's organ donation rate per million remains relatively low,3.86 ranking 48th globally in 2022,underscoring the need for increased public awareness and support for organ donation.
