期刊文献+
共找到3,370篇文章
< 1 2 169 >
每页显示 20 50 100
Design of a Landscape Device for Children from the Perspective of Embodied Cognition in the New Era
1
作者 HU Bingbing 《Journal of Landscape Research》 2024年第5期5-9,共5页
In recent years,embodied cognition has ushered in a new research upsurge in the academic field,and has become a hot topic in the field of cognitive psychology.In this paper,from the perspective of embodied cognition,t... In recent years,embodied cognition has ushered in a new research upsurge in the academic field,and has become a hot topic in the field of cognitive psychology.In this paper,from the perspective of embodied cognition,the interaction ways of a landscape device for children were discussed to achieve a more real and harmonious interaction between children and scenes.The research data of embodied cognition used by children was analyzed,and the drawbacks and breakthrough points of current landscape devices for children were discussed.The core characteristics of children’s growth period were extracted to establish children’s interaction model and summarize the interactive design methods of landscape devices for children.Embodied cognition has become the most intuitive way for children to know and understand the environment,and plays a pivotal role in children’s growth.Based on embodied cognition principle and interactive behavior mode,the interactive design of a landscape device for children was studied,and three interactive design modes,including simple and convenient interaction mode,multi-sensory interaction mode and game natural interaction mode were summarized.On the basis of this research,relevant design practice and research were carried out to bring a new vision to the design of children’s landscape. 展开更多
关键词 Embodied cognition children’s landscape Device design Interactive behavior pattern
在线阅读 下载PDF
Research on Children’s Game Activity Design Strategies Based on Embodied Cognition Theory
2
作者 Xiangmiao He 《Journal of Contemporary Educational Research》 2024年第4期54-58,共5页
Edutainment,in the kindergarten education stage,emphasizes the game as the basic activity and combines the content of education with the form of the game,thus it also forms the educational method of gamification teach... Edutainment,in the kindergarten education stage,emphasizes the game as the basic activity and combines the content of education with the form of the game,thus it also forms the educational method of gamification teaching.Through investigation and analysis,it is found that the current kindergarten game activity design has the problem of improper combination of educational content and game form.The current kindergarten game activity design has problems such as stereotypes,children’s lack of active learning opportunities in activities,teachers’insufficient theoretical understanding,inappropriate teacher guidance methods,and so on.Embodied cognition theory attaches importance to the important role of the body in the development of cognition,provides new guidance for classroom teaching,and opens up a new path for classroom teaching reform.Based on the perspective of embodied cognition theory,the concept of body and mind integration should be adhered to in kindergarten teaching with games as the basic activity,experiential teaching situation should be created,children’s subjective experience should be respected,and games and interactions should be designed to promote children’s physical and mental participation,thus laying a foundation for the realization of children’s individual freedom,autonomy,and all-round development.Therefore,this paper aims at the existing problems in the current kindergarten gamification teaching and discusses the design strategy of children’s game activities based on embodied cognition theory. 展开更多
关键词 Embodied cognition children’s play Game activity design
在线阅读 下载PDF
Endoscopic management of foreign bodies in the upper gastrointestinal tract in children:report of 60 cases and 65 pieces
3
作者 李兆申 许国铭 孙振兴 《Journal of Medical Colleges of PLA(China)》 CAS 1996年第1期73-75,共3页
From January 1978 to March 1995, 60 children (age :1 day-12 years) were examined endoscopically for their ingested foreign bodies. Sixty children had 65 pieces of foreign bodies, of which 16 pieces were impacted in th... From January 1978 to March 1995, 60 children (age :1 day-12 years) were examined endoscopically for their ingested foreign bodies. Sixty children had 65 pieces of foreign bodies, of which 16 pieces were impacted in the esophagus, 41 in the stomach and 8 in the duodenum. Sixty pieces of foreign bodies were successfully removed from 56 children without any complications. But 5 pieces of foreign bodies in 4 children failed to be taken out because the foreign bodies lodged in the second part of the duodenum. The successful rate was 93.3% in respect to the number of children, and 92.3% in respect to the pieces of foreign bodies. Among all the foreign bodies taken out, the longest one was 150 mm in length and 34 mm in width. Endoscopy was performed under general anaesthesia for most of the children with foreign bodies. The endoscope for adults has been used safely in these children. 展开更多
关键词 UPPER GAsTROINTEsTINAL FOREIGN bodies endoscopy children
在线阅读 下载PDF
Appendicitis combined with Meckel’s diverticulum obstruction, perforation, and inflammation in children: Three case reports 被引量:1
4
作者 Yi-Meng Sun Wang Xin +4 位作者 Yu-Fang Liu Zhe-Ming Guan Hao-Wen Du Ning-Ning Sun Yong-Dong Liu 《World Journal of Clinical Cases》 SCIE 2024年第4期865-871,共7页
BACKGROUND Meckel’s diverticulum is a common congenital malformation of the small intestine,with the three most common complications being obstruction,per-foration,and inflammation.To date,only a few cases have been ... BACKGROUND Meckel’s diverticulum is a common congenital malformation of the small intestine,with the three most common complications being obstruction,per-foration,and inflammation.To date,only a few cases have been reported world-wide.In children,the clinical symptoms are similar to appendicitis.As most of the imaging features are nonspecific,the preoperative diagnosis is not precise.In addition,the clinical characteristics are highly similar to pediatric acute appendicitis,thus special attention is necessary to distinguish Meckel’s diver-ticulum from pediatric appendicitis.Patients with poor disease control should undergo laparoscopic exploration to avoid serious complications,including intestinal necrosis,intestinal perforation and gastrointestinal bleeding.CASE SUMMARY This report presents three cases of appendicitis in children combined with intestinal obstruction,which was caused by fibrous bands(ligaments)arising from the top part of Meckel's diverticulum,diverticular perforation,and diver-ticular inflammation.All three patients,aged 11-12 years,had acute appendicitis as their initial clinical presentation.All were treated by laparoscopic surgery with a favorable outcome.A complete dataset including clinical presentation,dia-gnostic imaging,surgical information,and histopathologic findings was also provided.CONCLUSION Preoperative diagnosis of Meckel’s diverticulum and its complications is challenging because its clinical signs and complications are similar to those of appendicitis in children.Laparoscopy combined with laparotomy is useful for diagnosis and treatment. 展开更多
关键词 Meckel’s diverticulum Complications Intestinal obstruction PERFORATION Appendicitis in children Mesodiverticular band LIGAMENT Diverticular disease Case report
在线阅读 下载PDF
Western view of the management of gastroesophageal foreign bodies 被引量:3
5
作者 Aurora Burgos Luis Rábago Paloma Triana 《World Journal of Gastrointestinal Endoscopy》 CAS 2016年第9期378-384,共7页
The best modality for foreign body removal has beenthe subject of much controversy over the years.We have read with great interest the recent article by Souza Aguiar Municipal Hospital,Rio de Janeiro,Brazil,describing... The best modality for foreign body removal has beenthe subject of much controversy over the years.We have read with great interest the recent article by Souza Aguiar Municipal Hospital,Rio de Janeiro,Brazil,describing their experience with the management of esophageal foreign bodies in children.Non-endoscopic methods of removing foreign bodies(such as a Foley catheter guided or not by fluoroscopy)have been successfully used at this center.These methods could be an attractive option because of the following advantages:Shorter hospitalization time;easy to perform;no need for anesthesia;avoids esophagoscopy;and lower costs.However,the complications of these procedures can be severe and potentially fatal if not performed correctly,such as bronchoaspiration,perforation,and acute airway obstruction.In addition,it has some disadvantages,such as the inability to directly view the esophagus and the inability to always retrieve foreign bodies.Therefore,in Western countries clinical practice usually recommends endoscopic removal of foreign bodies under direct vision and with airway protection whenever possible. 展开更多
关键词 FOREIGN bodies children Foley CATHETER Flexible ENDOsCOPY
在线阅读 下载PDF
A novel binary effective medium model to describe the prepeak stressstrain relationship of combined bodies of rock-like material and rock 被引量:2
6
作者 Tienan Wang Yue Zhai +2 位作者 Huan Gao Yubai Li Ruifeng Zhao 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第5期601-616,共16页
Combined bodies of rock-like material and rock are widely encountered in geotechnical engineering,such as tunnels and mines.The existing theoretical models describing the stress-strain relationship of a combined body ... Combined bodies of rock-like material and rock are widely encountered in geotechnical engineering,such as tunnels and mines.The existing theoretical models describing the stress-strain relationship of a combined body lack a binary feature.Based on effective medium theory,this paper presents the governing equation of the“elastic modulus”for combined and single bodies under triaxial compressive tests.A binary effective medium model is then established.Based on the compressive experiment of concretegranite combined bodies,the feasibility of determining the stress threshold based on crack axial strain is discussed,and the model is verified.The model is further extended to coal-rock combined bodies of more diverse types,and the variation laws of the compressive mechanical parameters are then discussed.The results show that the fitting accuracy of the model with the experimental curves of the concretegranite combined bodies and various types of coal-rock combined bodies are over 95%.The crack axial strain method can replace the crack volumetric strain method,which clarifies the physical meanings of the model parameters.The variation laws of matrix parameters and crack parameters are discussed in depth and are expected to be more widely used in geotechnical engineering. 展开更多
关键词 Combined body stress-strain relationship Hooke’s law Effective medium theory stress threshold determination
在线阅读 下载PDF
On Reverses of the Blaschke-Santalo Inequality for Convex Bodies 被引量:2
7
作者 WANG Wei-dong ZHOU Yan-ping 《Chinese Quarterly Journal of Mathematics》 CSCD 2013年第4期605-611,共7页
Reisner proved a reverse of the Blaschke-Santal5 inequality for zonoid bodies, Bourgain and Milman showed another reverse of the Blaschke-Santal5 inequality for centered convex bodies. In this paper, two reverses of t... Reisner proved a reverse of the Blaschke-Santal5 inequality for zonoid bodies, Bourgain and Milman showed another reverse of the Blaschke-Santal5 inequality for centered convex bodies. In this paper, two reverses of the Blaschke-Santal5 inequality for convex bodies are given by the Petty projection inequality and above two reverses. Further, using above methods, we also obtain two analogues of the Petty's conjecture for projection bodies, respectively. 展开更多
关键词 convex body Blaschke-santal5 inequality REVERsE Petty's conjecture
在线阅读 下载PDF
Relationship between Authoritative Parenting Style and Preschool Children’s Emotion Regulation:A Moderated Mediation Model
8
作者 Yan Jin Wei Chen 《International Journal of Mental Health Promotion》 2024年第3期189-198,共10页
An authoritative parenting style has been shown to promote children’s emotion regulation in European-American family studies.However,little is known about how sleep problems and the child’s sibling status in Chinese... An authoritative parenting style has been shown to promote children’s emotion regulation in European-American family studies.However,little is known about how sleep problems and the child’s sibling status in Chinese families affect this relationship.Based on family system theory,this study attempts to better understand the relationship between authoritative parenting style and emotion regulation.Mothers of preschool children in Chinese kindergartens completed questionnaires about their children’s sleep habits,their authoritative parenting styles,and children’s emotion regulation.A total of 531 children participated in this study.Results showed that authoritative parenting was positively associated with emotional regulation.Sleep problems mediated the effects of authoritative parenting style on emotion regulation.The child’s sibling status moderated the mediating effects of sleep problems in authoritative parenting and emotion regulation relationships.Specifically,the relationship between the authoritative parenting style and sleep problems was significant for only children,while birth order had no significant influence on the authoritative parenting style and sleep problems in two-child families.These findings suggest that a lowauthoritative parenting style predicts low emotion regulation through sleep problems,and this depends on the child’s sibling status,indicating that children without siblings may impair emotion regulation due to increased sleep problems. 展开更多
关键词 sleep problem emotional regulation authoritative parenting child’s sibling status preschool children
在线阅读 下载PDF
The Research of the Flow of Bodies with Use of the Vector Form of the Newton’s Law for the Viscous Liquid 被引量:2
9
作者 Andrey N. Volobuev Eugene S. Petrov 《Engineering(科研)》 2011年第2期162-167,共6页
On the basis of the vector formula of the Newton’s law for a viscous liquid and the integrated vector form of the equation of an impulse for a viscous liquid for resistance and carrying power of a profile of any form... On the basis of the vector formula of the Newton’s law for a viscous liquid and the integrated vector form of the equation of an impulse for a viscous liquid for resistance and carrying power of a profile of any form and the big length dependences are found in a stream. Application of the found dependences at a circulating flow of the cylinder located across a stream is showed. The analysis of a tensor of viscosity for laminar and turbulent flow is carried out. 展开更多
关键词 Newton’s LAW for VIsCOsITY A Body FLOW CIRCULATION of speed Resistance Factor A VIsCOsITY TENsOR
在线阅读 下载PDF
On Translation of Children’s Literature Based on Reception Aesthetics:A Case Study of The Secret Garden
10
作者 HOU Wen-lan LI Ju-yuan 《Journal of Literature and Art Studies》 2024年第3期194-200,共7页
Grounded in reader-centered theories,Reception Aesthetics prioritizes the active engagement and acceptance of target readers.This study examines the translation of children’s literature through the lens of Reception ... Grounded in reader-centered theories,Reception Aesthetics prioritizes the active engagement and acceptance of target readers.This study examines the translation of children’s literature through the lens of Reception Aesthetics,using Li Wenjun’s rendition of The Secret Garden as a case study.The objective is to scrutinize various aspects of the translation-including vocabulary,syntax,rhetorical devices,and cultural nuances-and to discern how the adaptation and application of diverse translation strategies cater to the aesthetic expectations. 展开更多
关键词 Reception Aesthetics translation of children’s literature The secret Garden
在线阅读 下载PDF
Reflections on Conducting Kindergarten Language Education Activities Based on Children’s Literature
11
作者 Pujun Tong 《Journal of Contemporary Educational Research》 2024年第3期118-123,共6页
In early childhood education,language education is a crucial component,yet in kindergarten teaching,there often exists issues such as“emphasis on knowledge and neglect of practice.”To address this problem,teachers n... In early childhood education,language education is a crucial component,yet in kindergarten teaching,there often exists issues such as“emphasis on knowledge and neglect of practice.”To address this problem,teachers need to incorporate children’s literature in a reasonable manner to create a conducive environment for language education for young children.This article analyzes and discusses the significance of integrating children’s literature into kindergarten language education activities,and proposes strategies for addressing the current issues in kindergarten language education activities and conducting them based on children’s literature. 展开更多
关键词 KINDERGARTEN Language education children’s literature
在线阅读 下载PDF
Research on the Influence of Family Education on Children’s Behavioral Habits
12
作者 Jiayi Wen 《Journal of Contemporary Educational Research》 2024年第8期176-180,共5页
Under the background of the all-round deepening of quality education,the cultivation of comprehensive quality has become the main theme of contemporary education reform.Good behavior and habits are of great significan... Under the background of the all-round deepening of quality education,the cultivation of comprehensive quality has become the main theme of contemporary education reform.Good behavior and habits are of great significance to children’s future learning,growth,and development.Through literature review and other methods,this paper analyzes the current situation of children’s family education and the influence of family education on the cultivation of children’s behavioral habits and provides some strategies for cultivating children’s good behavioral habits in family education. 展开更多
关键词 Family education children’s behavior Habit cultivation PARENTs
在线阅读 下载PDF
The Market Development of Children’s Go Training and the Difficulty and Countermeasure Analysis of Go Training
13
作者 Yangcheng Zhao 《Proceedings of Business and Economic Studies》 2024年第3期161-165,共5页
The children’s Go training market is experiencing vigorous growth but also faces several challenges.As the importance of Go in cultural education increases,the market expands,with growing demand and involvement from ... The children’s Go training market is experiencing vigorous growth but also faces several challenges.As the importance of Go in cultural education increases,the market expands,with growing demand and involvement from training and educational institutions.However,the market encounters difficulties such as a shortage of high-quality Go coaches,uniformity in training content and methods,and high training costs.To address these issues,measures can be taken to strengthen the team of Go coaches,diversify training content and methods,and optimize the training cost structure,thereby promoting the healthy development of the children’s Go training market. 展开更多
关键词 children’s Go Training market development Go training
在线阅读 下载PDF
A Study of Health Prescribing for Children with Tourette’s Disorders in Children’s Health Education Specialty Care Clinics
14
作者 Wenping Yang Le Wang +2 位作者 Sha Wang Nannan Ma Li Mei 《Journal of Clinical and Nursing Research》 2024年第7期261-266,共6页
Objective:This study designs and implements the health prescription of children’s health education specialized nursing clinic based on the physical and mental characteristics of children with Tourette’s syndrome.Met... Objective:This study designs and implements the health prescription of children’s health education specialized nursing clinic based on the physical and mental characteristics of children with Tourette’s syndrome.Methods:Applying the evidence-based nursing model and nursing intervention theory based on the survey research by searching China Knowledge Network,Wanfang Database and Wipro Chinese Science and Technology Journal Database,the study collected the literature on the health prescription intervention research in children’s Tourette’s disorders health education in children’s health education of specialized nursing outpatient clinic for review and combined with the specialty characteristics to formulate“Children’s Tourette’s Disorder Health Education Prescription.”Results:Tourette’s syndrome in children is a common pediatric neurological disorder,mainly manifested as involuntary,rapid and repeated muscle twitching and vocal tics,which brings serious psychological pressure and life disturbance to the affected children.Conclusion:For children with Tourette’s syndrome,healthcare professionals should give enough care and understanding to the children and their parents,provide timely and effective health education to them,help them improve their bad behavioral habits,establish correct cognitive attitudes,enhance self-confidence,improve patient compliance,reduce the frequency of recurrence,reduce the incidence of complications and promote children’s physical and mental health development. 展开更多
关键词 children’s health education specialty care clinic Childhood Tourette’s disorder Health prescription
在线阅读 下载PDF
Aspiration of foreign bodies that allow air passage through
15
作者 Demet Can Ozge Yilmaz +2 位作者 Suna Asilsoy Saniye Gulle Hasan Yuksel 《Open Journal of Pediatrics》 2011年第4期90-93,共4页
Foreign body aspiration is commonly encountered in children. In cases that foreign body does not disturb respiratory physiology, clinical and radiological diagnosis may be delayed leading to severe complications. Four... Foreign body aspiration is commonly encountered in children. In cases that foreign body does not disturb respiratory physiology, clinical and radiological diagnosis may be delayed leading to severe complications. Four cases with aspiration of a foreign body not obstructing ventilation and without typical clinical and radiological findings are discussed. 展开更多
关键词 FOREIGN BODY AsPIRATION children Ventilation Air PAssAGE
在线阅读 下载PDF
Asymptotic properties of two affine invariants for 1-unconditional convex bodies
16
作者 谢富生 何斌吾 易军 《Journal of Shanghai University(English Edition)》 CAS 2010年第3期223-227,共5页
Let K be a 1-unconditional convex bodies in Euclidean spaces.We study the asymptotic properties of two affine invariants m2(K) and S2(K) for a random simplex inside K.As an application,we discuss the asymptotic pr... Let K be a 1-unconditional convex bodies in Euclidean spaces.We study the asymptotic properties of two affine invariants m2(K) and S2(K) for a random simplex inside K.As an application,we discuss the asymptotic properties of two affine invariants m2(Bpn ) and S2(Bpn ),where Bpn = {x ∈ Rn : ‖x‖ p 1}. 展开更多
关键词 convex body 1-unconditional convex body isotropic constant sylvester’s problem random simplex
在线阅读 下载PDF
Colliding Bodies Optimization with Machine Learning Based Parkinson’s Disease Diagnosis
17
作者 Ashit Kumar Dutta Nazik M.A.Zakari +1 位作者 Yasser Albagory Abdul Rahaman Wahab Sait 《Computer Systems Science & Engineering》 SCIE EI 2023年第3期2195-2207,共13页
Parkinson’s disease(PD)is one of the primary vital degenerative diseases that affect the Central Nervous System among elderly patients.It affect their quality of life drastically and millions of seniors are diagnosed... Parkinson’s disease(PD)is one of the primary vital degenerative diseases that affect the Central Nervous System among elderly patients.It affect their quality of life drastically and millions of seniors are diagnosed with PD every year worldwide.Several models have been presented earlier to detect the PD using various types of measurement data like speech,gait patterns,etc.Early identification of PD is important owing to the fact that the patient can offer important details which helps in slowing down the progress of PD.The recently-emerging Deep Learning(DL)models can leverage the past data to detect and classify PD.With this motivation,the current study develops a novel Colliding Bodies Optimization Algorithm with Optimal Kernel Extreme Learning Machine(CBO-OKELM)for diagnosis and classification of PD.The goal of the proposed CBO-OKELM technique is to identify whether PD exists or not.CBO-OKELM technique involves the design of Colliding Bodies Optimization-based Feature Selection(CBO-FS)technique for optimal subset of features.In addition,Water Strider Algorithm(WSA)with Kernel Extreme Learning Machine(KELM)model is also developed for the classification of PD.CBO algorithm is used to elect the optimal set of fea-tures whereas WSA is utilized for parameter tuning of KELM model which alto-gether helps in accomplishing the maximum PD diagnostic performance.The experimental analysis was conducted for CBO-OKELM technique against four benchmark datasets and the model portrayed better performance such as 95.68%,96.34%,92.49%,and 92.36%on Speech PD,Voice PD,Hand PD Mean-der,and Hand PD Spiral datasets respectively. 展开更多
关键词 Parkinson’s disease colliding bodies optimization algorithm feature selection metaheuristics classification kelm model
在线阅读 下载PDF
Bacterial Biofilm in Water Bodies of Cherrapunjee: The Rainiest Place on Planet Earth
18
作者 Subhro Banerjee Sudha Rai +1 位作者 Barnali Sarma Santa Ram Joshi 《Advances in Microbiology》 2012年第4期465-475,共11页
Bacterial attachment is influenced by the cell surface, attachment media and other environmental factors. Bacterial community composition involved in biofilm formation in extremely high rainfall areas like Cherrapunje... Bacterial attachment is influenced by the cell surface, attachment media and other environmental factors. Bacterial community composition involved in biofilm formation in extremely high rainfall areas like Cherrapunjee has not been reported. The present study was undertaken to characterize bacteria involved in biofilm formation on different substrata in water bodies of Cherrapunjee, the highest rainfall receiving place on planet earth and to assess if the continuous rainfall has an effect on nature and colonization of biofilm bacteria. We developed the biofilm bacteria on stainless steel and glass surfaces immersed in water bodies of the study sites. Isolation of biofilm bacteria were performed on different culture media followed by estimation of protein and carbohydrate content of bacterial exopolysaccharides. 16S rRNA gene sequences were amplified for molecular characterization. The results showed that the biofilm bacterial diversity in water bodies of Cherrapunjee was influenced by substratum and was observed more in stainless steel than glass surface. Scanning electron microscopy images revealed that biofilm microstructure may represent a key determinant of biofilm growth and physiology of associated bacteria. The overall protein content of the extracted EPS of all the isolates were relatively higher than the carbohydrate content. Diverse bacteria proliferated on the substrata regardless of each other's presence, with more diverse bacteria colonizing the substrata on 7th day compared to 15th day of incubation. The biofilm bacteria compositions in the highest rainfall receiving habitat were not distinctly different from reports available, hence not unique from other water bodies. 展开更多
关键词 Cherrapunjee Rainiest PLACE Water bodies BACTERIAL BIOFILM 16s RDNA EPs
在线阅读 下载PDF
Protein Bodies in Cotyledon Cells Exhibit Differential Patterns of Legumin-Like Proteins Mobilization during Seedling Germinating States
19
作者 Jose C. Jimenez-Lopez Maria C. Hernandez-Soriano 《American Journal of Plant Sciences》 2013年第12期2444-2454,共11页
Olive (Olea europaea L.) tree is one of the most extensive and important agricultural crop in Mediterranean countries due to its beneficial health and nutritional properties and its high economic value. Currently, oli... Olive (Olea europaea L.) tree is one of the most extensive and important agricultural crop in Mediterranean countries due to its beneficial health and nutritional properties and its high economic value. Currently, olive tree constitutes the sixth most important cultivated plant in the world, spreading from the Mediterranean region of origin to new production areas such as Australia, South and North America and South Africa. However, the mobilization processes of storage materials i.e. reserve proteins during seed germination, which are largely involved in essential physiological process including plant growth and development, remain poorly understood. Morphometric and immunohistochemistry analyses of protein bodies contained in olive seed storage tissues, cotyledon and endosperm, were performed by using different microscopy techniques, including light (bright-field and fluorescence) microscopy and transmission electron microscopy. Furthermore, we used legumin-like proteins (11S-type globulins) as a molecular marker to study the mobilization of reserve proteins from PBs of cotyledons at germinating seedling stages by using immunofluorescence assays. Results demonstrated that cotyledon and endosperm are characterized by distinct PBs populations containing legumin-like proteins, distinctly discriminated by the number of PBs per cell and tissue, size, immunofluorescence and histochemical staining. These features reflect differential PBs biogenesis during development and maturation processes in olive seed tissues endosperm and cotyledon, in relation to proteins (polypeptides) final composition, SSPs processing and/or packaging during seed maturation. Three different mobilization patterns of legumin-like proteins were identified for the first time in cotyledon PBs during seedling germinating process. Mature proteins composition and/or processing, cell types and enzyme composition and/or differential activation have been discussed as key features determining how proteins mobilize from PBs for further degradation in the cotyledon. 展开更多
关键词 11s GLOBULINs COTYLEDON Endosperm In Vitro Germination Legumin-Like PROTEINs Olea europaea L. Protein bodies seed PROTEINs MOBILIZATION
在线阅读 下载PDF
Recent progress and concerns in dementia: Distinguishing Alzheimer's disease and dementia with Lewy bodies via biochemical markers in the cerebrospinal fluid
20
作者 Peizhong Mao 《Advances in Biological Chemistry》 2012年第2期176-190,共15页
Dementia is mainly a neurodegenerative disorder involved in several systems, including central nervous system, endocrinology/metabolism system and circulatory system. Alzheimer’s disease (AD) and dementia with Lewy b... Dementia is mainly a neurodegenerative disorder involved in several systems, including central nervous system, endocrinology/metabolism system and circulatory system. Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) are the most common forms of the dementia, accounting for 60% - 80% and 10% - 20% of all cases, respectively. DLB is defined by widespread neocortical, limbic and brainstem Lewy bodies but frequently accompanied by variable levels of AD pathology. This pathological and clinical overlap makes their differential diagnosis complicated. Recent advances in the identification of disease bio-markers now make it possible to detect and distinguish their pathology in the early or preclinical stage of the diseases, even in cognitively normal individuals. In addition to the key biomarkers (amyloid β or Aβ, tau and α-synuclein), neurotrophins such as cocaine- and amphetamine-regulated transcript (CART) have also drawn attention due to their expressions and functions. This article summarizes the progress in the definition, pathology and diagnosis of dementia, with a focus on potential biochemical markers in the cere-brospinal fluid (CSF) in the differential diagnosis of the main forms of dementia. To prediction or early diagnosis of dementia, the role of specific and sensitive CSF biomarkers seems to be crucial in a routine clinical setting. The concerns and challenges in the biomarker field are also discussed. 展开更多
关键词 DEMENTIA Alzheimer’s DEMENTIA DEMENTIA with LEWY Body BIOMARKER OXIDATIVE stress Differential Diagnosis
在线阅读 下载PDF
上一页 1 2 169 下一页 到第
使用帮助 返回顶部