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CO_(2)驱后水气交替注入驱替特征及剩余油启动机制 被引量:1
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作者 孙成岩 《大庆石油地质与开发》 CAS 北大核心 2024年第1期52-58,共7页
水气交替注入(WAG)是特低渗透油藏提高采收率的有效手段之一,但在CO_(2)连续气驱后实施WAG驱,仍然存在驱替特征模糊、剩余油启动机制不明确等问题。以海拉尔油田贝14区块为研究对象,借助Micro⁃CT研究WAG驱启动剩余油的微观作用机制,同... 水气交替注入(WAG)是特低渗透油藏提高采收率的有效手段之一,但在CO_(2)连续气驱后实施WAG驱,仍然存在驱替特征模糊、剩余油启动机制不明确等问题。以海拉尔油田贝14区块为研究对象,借助Micro⁃CT研究WAG驱启动剩余油的微观作用机制,同时通过长岩心驱替实验研究CO_(2)驱后水气交替注入的驱替特征。Micro⁃CT实验结果表明:目标区块大孔隙的体积比例超过85%,在被CO_(2)全部动用后成为了气窜通道,采收率仅47.95%;CO_(2)驱后WAG驱不仅启动次级大孔隙中的剩余油,对中小孔隙的剩余油也有不同程度的动用。长岩心实验结果表明:在CO_(2)驱后开展WAG驱,水和气段塞需要交替注入一定量(0.40 PV左右)后采收率才能大幅度增加,气水比和段塞尺寸存在最优值,分别为1∶1和0.10 PV,该条件下WAG驱的采收率增幅主要由第3、4交替轮次所贡献,10轮次的水气交替注入可在CO_(2)驱的基础上提高采收率18.68百分点。研究成果可为特低渗透油藏CO_(2)驱后进一步提高采收率提供理论支撑。 展开更多
关键词 水气交替注入(WAG) 特低渗透油藏 CO_(2)驱 剩余油启动机制 提高采收率
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深水碳酸盐岩油藏高含CO_(2)产出气回注驱油实验研究
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作者 李云波 刘成彬 +3 位作者 叶禹 杨朝蓬 余洋 李剑 《天然气与石油》 2024年第6期57-64,共8页
深水碳酸盐岩M油藏气油比高达200~350 m^(3)/m^(3),产出气中CO_(2)含量超过40%。为减少碳排放,充分利用产出气的高含CO_(2)烃类气体提高驱油效率,开展了模拟储层条件的连续气驱、水驱和水气交替(Water-Alternating-Gas,WAG)驱驱油实验,... 深水碳酸盐岩M油藏气油比高达200~350 m^(3)/m^(3),产出气中CO_(2)含量超过40%。为减少碳排放,充分利用产出气的高含CO_(2)烃类气体提高驱油效率,开展了模拟储层条件的连续气驱、水驱和水气交替(Water-Alternating-Gas,WAG)驱驱油实验,分析研究了不同驱替方式的驱油效率、岩心非均质性、注气速度、注入压力对WAG驱驱油效果的影响规律。研究结果表明:WAG驱驱油效率最高可达71.88%,连续气驱驱油效率为56.83%,分别较水驱(驱油效率为42.08%)高29.8个百分点和14.75个百分点;岩心非均质性、注气速度、注入压力对WAG驱驱油效率具有较大影响,岩心非均质性越强,控水和延缓气窜效果越差,驱油效率越低;高于合理的速度注气,见气时刻提前,最终驱油效率降低;注入压力应满足混相驱条件,有利于提高驱油效率。研究结果为深水碳酸盐岩油藏利用高含CO_(2)产出气WAG驱驱油提供了依据。 展开更多
关键词 WAG 物理模拟 相似准则 驱油效率
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致密油的CO_(2^(-))水注入驱替模型的仿真实验设计 被引量:1
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作者 周丽霞 刘雨琪 +2 位作者 罗亚凌 赵承恩 王磊 《实验技术与管理》 CAS 北大核心 2024年第2期156-161,共6页
该文设计了CO_(2^(-))水注入驱替致密油的仿真实验,引入分子动力学模拟方法,模拟了水驱、CO_(2)驱和CO_(2^(-))WAG驱替纳米孔道内致密油的微观动力学过程,研究了驱替过程中的气、水、油的流动行为、所受阻力及各组分之间的微观相互作用... 该文设计了CO_(2^(-))水注入驱替致密油的仿真实验,引入分子动力学模拟方法,模拟了水驱、CO_(2)驱和CO_(2^(-))WAG驱替纳米孔道内致密油的微观动力学过程,研究了驱替过程中的气、水、油的流动行为、所受阻力及各组分之间的微观相互作用,分析了三种驱替方法的驱替效率、驱替速率和临界驱动压强。教学实践证明,学生通过本实验深刻理解了油气田开发的不同驱替方式的微观过程以及不同分子之间的相互作用对驱替过程的影响,掌握了研究油气田开发的分子动力学模拟方法,为进一步开展相关创新研究打下了良好的基础。 展开更多
关键词 分子动力学 CO_(2^(-))WAG驱 临界驱动压强 油气田开发
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Characteristics of water alternating CO_(2)injection in low-permeability beach-bar sand reservoirs
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作者 Maolei Cui Rui Wang +1 位作者 Zengmin Lun Chengyuan Lv 《Energy Geoscience》 EI 2024年第1期224-229,共6页
Water flooding can be ineffective in highly heterogeneous low-permeability beach-bar sand reservoirs.The introduction of CO_(2)flooding helps boost the oil production of the reservoirs but only in an early stage.Durin... Water flooding can be ineffective in highly heterogeneous low-permeability beach-bar sand reservoirs.The introduction of CO_(2)flooding helps boost the oil production of the reservoirs but only in an early stage.During the late stage of flooding,gas channeling would occur.Water alternating gas(CO_(2))(WAG)process can be used to delay gas channeling and improve the effect of CO_(2)injection,though its adaptability to beach-bar sand reservoirs remains unclear.In order to clarify CO_(2)injection characteristics in these reservoirs,experiments were carried out in high-temperature high-pressure NMR on-line displacement experiment apparatus to simulate different flooding modes on synthetic cores that can reflect the vertical heterogeneity of beach-bar reservoirs.Different CO_(2)injection modes were implemented on these cores and the displacement characteristics and residual oil distribution features during both WAG injection and continuous CO_(2)injection were analyzed quantitatively and qualitatively.The results show that the scheme of WAG injection after continuous CO_(2)injection can obtain better oil displacement efficiency than that of the scheme of continuous CO_(2)injection after WAG injection,but there is no significant difference in respect of oil displacement efficiency of WAG flooding between the mode of bar-injection e beach-production(injection into bar sand e production from beach sand)and the mode of beach-injection e beach-production(injection into and production from beach sand),with the former mode having a higher oil recovery rate.The wider pore-size distribution range of microscopic residual oil after WAG injection shows great potential of enhancing oil recovery from subsequent continuous gas injection.When WAG injection is implemented prior to continuous CO_(2)injection,the displacement effect of the latter is more significant.This research may provide a theoretical basis for CO_(2)EOR in this type of reservoirs. 展开更多
关键词 Beach-bar sand Low permeability CO_(2)injection WAG NMR
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基于MultiBoost的最小分类误差算法 被引量:2
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作者 王元珍 乐树彬 《小型微型计算机系统》 CSCD 北大核心 2005年第11期1948-1950,共3页
基于MultiBoost分类组装技术,提出了一种用增量交叉验证技术求MultiBoost最小分类误差的算法,以使之在指定分类器数量T的范围内找出具有最小分类误差的合成分类器.
关键词 分类组装算法 最小分类误差 MultiBoost wagging BAGGING ADABOOST
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利用ASP动态实现网站设计与生成 被引量:1
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作者 周安峻 黄方 陈涛 《渭南师范学院学报》 2010年第5期44-48,共5页
文章通过ASP与SQL进行动态网站的设计与生成.它为用户提供友好的设计界面,把用户的交互式的描述信息分类后存入后台数据库,在需要时通过对数据库中的数据进行选取,使用预先定义的网页模板,从而生成整个网站的HTML代码文件.
关键词 WAGS 数据对象 动态生成
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大容量闪存K9WAG08U0A的硬软件接口设计方法 被引量:1
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作者 李明磊 潘文亮 《工业控制计算机》 2010年第4期54-55,共2页
三星公司的NAND-Flash存储器K9WAG08U存储容量大,读写速度快且运行稳定,特别适用于低功耗,小型化的嵌入式系统。通过具体实例介绍它的软硬件接口设计方法。
关键词 NAND—Flash存储 K9WAG08U0A 软硬件接口
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气水交替驱提高采收率室内实验研究 被引量:5
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作者 秦正山 罗沛 +2 位作者 刘先山 张文昌 周建良 《石油化工高等学校学报》 CAS 2019年第6期52-56,共5页
国内外矿场试验表明,WAG驱可进一步提高原油采收率5%~10%,是三次采油阶段经济、有效提高采收率的驱替方式。借助室内驱替实验,利用改进的模拟岩心,通过设置实验对照组,揭示和明确了WAG驱提高采收率的作用机理。结果表明,WAG驱可减缓气窜... 国内外矿场试验表明,WAG驱可进一步提高原油采收率5%~10%,是三次采油阶段经济、有效提高采收率的驱替方式。借助室内驱替实验,利用改进的模拟岩心,通过设置实验对照组,揭示和明确了WAG驱提高采收率的作用机理。结果表明,WAG驱可减缓气窜,改变不利的水油流度比。注入气加强了三相分子之间的交换、扩散、渗吸及突破作用。水气交替注入后水驱封堵高渗带,气驱驱扫微小孔隙,并伴随重力分异效果,且驱替过程是水在孔隙中的缚存状态不断打破、不断重建的一个动态过程;注入水交替封堵大孔隙,削弱了注入气对流体的突破作用,改善了吸水剖面,延长油井见水时间,有助于提高原油采收率。对于非均质性严重的储层,交替注水产生的动态封堵可进一步提高WAG驱油效果。 展开更多
关键词 WAG驱 流度比 提高采收率 作用机理
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低渗透油藏CO2变周期气水交替注入气水比理论设计 被引量:3
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作者 侯刚刚 杨勇 +3 位作者 王伟 蔡国新 刘同敬 侯吉瑞 《科学技术与工程》 北大核心 2020年第17期6857-6864,共8页
基于开发过程中饱和度、渗透率、分流率不断变化的特点,提出变周期水气交替注入(water alternating gas,WAG)气水比理论设计的概念。从油、气、水三相渗流力学原理出发,借助三相相对渗透率表征模型,建立各相饱和度与相对渗透率间的函数... 基于开发过程中饱和度、渗透率、分流率不断变化的特点,提出变周期水气交替注入(water alternating gas,WAG)气水比理论设计的概念。从油、气、水三相渗流力学原理出发,借助三相相对渗透率表征模型,建立各相饱和度与相对渗透率间的函数关系,得到各相饱和度与流度、气水比、流度偏离系数等相关参数的函数关系。流度偏离系数为引入的新参数,用于考察气水两相流动能力偏离水的流动能力幅度。采用枚举法,得到三相饱和度与气水比和流度偏离系数的关系图版,初步确定三相流动范围内气水比和流度偏离系数的取值范围。根据流度偏离系数和气水比关系曲线的特征点与含水饱和度之间的相互关系,最终确定变周期WAG气水比理论取值的合理范围。通过对实际区块气水比理论设计研究表明:合理气水比与含水饱和度是幂指数的函数关系;目标区块气水比的取值范围为0~34,流度偏离系数的取值范围为0~518。在中低含水阶段,建议WAG气水比理论设计数值为2;在中含水阶段,建议WAG气水比理论设计数值为1;在中高含水阶段,建议WAG气水比理论设计数值为0.5。该方法得到的变周期WAG气水比数值与数值模拟方法得到的结论相同,填补了变周期WAG气水比理论设计空白,对于完善变周期WAG其他参数的理论设计具有启发和借鉴作用。 展开更多
关键词 低渗透油藏 变周期水气交替注入(WAG) 气水比 流度偏离系数 理论设计
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低渗透非均质油藏WAG注入参数优化实验及提高采收率机理研究 被引量:13
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作者 郝宏达 赵凤兰 +5 位作者 侯吉瑞 宋兆杰 侯利斌 王志兴 李文峰 付忠凤 《石油科学通报》 2016年第2期233-240,共8页
低渗透非均质油藏通常具有气驱效率低、气窜严重等特点,气水交替注入(WAG)能够在一定程度上改善气驱的驱油效果。本文借助室内实验明确了WAG驱在低渗透非均质油藏的适应性,并从流度控制能力的角度分析了WAG驱提高采收率的作用机理。相... 低渗透非均质油藏通常具有气驱效率低、气窜严重等特点,气水交替注入(WAG)能够在一定程度上改善气驱的驱油效果。本文借助室内实验明确了WAG驱在低渗透非均质油藏的适应性,并从流度控制能力的角度分析了WAG驱提高采收率的作用机理。相对于均质油藏,WAG驱在渗透率级差较小的低渗透非均质油藏中具有更好的适应性。对于非均质程度较弱的低渗/特低渗透油藏,WAG驱可充分发挥其流度控制作用,启动低渗层中的原油,扩大注入气的波及体积,改善注入气的驱油效果。WAG驱注入参数优化结果表明,在注气速度为0.3 mL/min、段塞尺寸为0.1 PV和气水比为l:1的注入参数条件下,WAG驱可在水驱的基础上使低渗透非均质模型的采收率提高20.96个百分点。 展开更多
关键词 低渗透油藏 非均质性 WAG 流度控制 提高采收率
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平面非均质油藏水气交替驱提高采收率室内实验研究 被引量:3
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作者 秦正山 罗沛 +2 位作者 刘先山 张文昌 谢晶 《云南化工》 CAS 2018年第1期50-51,共2页
水气交替(WAG)驱提高采收率技术和应用研究在我国处于起步阶段。借助室内驱替实验,明确了WAG驱在平面非均质油藏的适应性及其提高采收率的作用机理。将并联式填砂管替代常规岩心夹持器,进一步减弱了长岩心驱替产生的末端效应和应力敏感... 水气交替(WAG)驱提高采收率技术和应用研究在我国处于起步阶段。借助室内驱替实验,明确了WAG驱在平面非均质油藏的适应性及其提高采收率的作用机理。将并联式填砂管替代常规岩心夹持器,进一步减弱了长岩心驱替产生的末端效应和应力敏感现象,模拟真实的平面非均质油藏条件。实验结果表明,WAG驱可减缓气窜,改善吸水剖面。注入N2可加强三相分子之间的交换、扩散、渗吸作用。对于非均质性严重的储层,水气交替注入后水驱封堵高渗带,气驱驱扫小孔隙,帮助形成稳定的驱替前缘,提高低渗储层的驱油效率。 展开更多
关键词 WAG驱 并联式填砂管 油藏适应性
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C+W网络无缝切换研究
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作者 刘源 孙智强 邵震 《电信科学》 北大核心 2011年第S1期133-139,共7页
对基于客户端实现的cdma2000 Ev-Do+Wi-Fi无缝切换功能进行研究,并对切换原理、切换流程、切换算法、策略及通过现网测试评估分流Ev-Do效果等方面进行描述。Ev-Do和Wi-Fi网络无缝切换功能,为CDMA用户的业务流由Wi-Fi网络分担给出了技术... 对基于客户端实现的cdma2000 Ev-Do+Wi-Fi无缝切换功能进行研究,并对切换原理、切换流程、切换算法、策略及通过现网测试评估分流Ev-Do效果等方面进行描述。Ev-Do和Wi-Fi网络无缝切换功能,为CDMA用户的业务流由Wi-Fi网络分担给出了技术解决方法,对C+W分流工作,具有积极的现实意义。 展开更多
关键词 Wi-Fi分流 WAG 无缝切换 WI-FI EV-DO
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Remaining oil distribution in models with different heterogeneities after CO_(2) WAG injection:Visual research by nuclear magnetic resonance technique 被引量:3
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作者 WANG Ye-fei LI Zong-yang +2 位作者 ZHANG Shi-ming LIU De-xin DING Ming-chen 《Journal of Central South University》 SCIE EI CAS CSCD 2021年第5期1412-1421,共10页
Water alternating gas(WAG)injection is a widely used strategy for enhancing oil recovery(EOR)during gas flooding,and the mechanisms,operating parameters,and influencing factors of which have been extensively studied.H... Water alternating gas(WAG)injection is a widely used strategy for enhancing oil recovery(EOR)during gas flooding,and the mechanisms,operating parameters,and influencing factors of which have been extensively studied.However,with respect to its capacity in expanding macroscopic sweep volume under varying heterogeneities,the related results appear inadequate.In this research,three cores with different heterogeneities were used and flooded by the joint water and CO_(2) WAG,then the effects of heterogeneity on oil recovery were determined.More importantly,the cores after CO_(2) WAG injection were investigated using the nuclear magnetic resonance(NMR)technique for remaining oil distribution research,which could help us to understand the capacity of CO_(2) WAG in enlarging sweep volume at different heterogeneities.The results show that the presence of heterogeneity may largely weaken the effectiveness of water flooding,the more severe the heterogeneity,the worse the water flooding.The WAG injection of CO_(2) performs well in EOR after water flooding for all the cores with different heterogeneities;however,it could barely form a complete or full sweep throughout the low-permeability region,and un-swept bypassed regions remain.The homogeneous core is better developed by the injection of the joint water and CO_(2) WAG than the heterogeneous and fractured cases. 展开更多
关键词 heterogeneous reservoir enhancing oil recovery CO_(2)WAG injection sweep volume remaining oil nuclear magnetic resonance
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Numerical analysis of water-alternating-CO_(2) flooding for CO_(2)-EOR and storage projects in residual oil zones 被引量:1
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作者 Boyu Liu Jun Yao Tunan Sun 《International Journal of Coal Science & Technology》 EI CAS CSCD 2023年第5期1-11,共11页
Residual oil zones(ROZs)have high residual oil saturation,which can be produced using CO_(2) miscible flooding.At the same time,these zones are good candidates for CO_(2) sequestration.To evaluate the coupled CO_(2)-E... Residual oil zones(ROZs)have high residual oil saturation,which can be produced using CO_(2) miscible flooding.At the same time,these zones are good candidates for CO_(2) sequestration.To evaluate the coupled CO_(2)-EOR and storage perfor-mance in ROZs for Water-Alternating-CO_(2)(WAG)flooding,a multi-compositional CO_(2) miscible model with molecular diffusion was developed.The effects of formation parameters(porosity,permeability,temperature),operation parameters(bottom hole pressure,WAG ratio,pore volume of injected water),and diffusion coeffcient on the coupled CO_(2)-EOR and storage were investigated.Five points from the CO_(2) sequestration curve and the oil recovery factor curve were selected to help better analyze coupled CO_(2)-EOR and storage.The results demonstrate that enhanced performance is observed when formation permeability is higher and a larger volume of water is injected.On the other hand,the performance diminishes with increasing porosity,molecular diffusion of gas,and the WAG ratio.When the temperature is around 100℃,coupled CO_(2)-EOR and storage performance is the worst.To achieve optimal miscible flooding,it is recommended to maintain the bottom hole pressure(BHP)of the injection well above 1.2 minimum miscibility pressure(MMP),while ensuring that the BHP of the production well remains sufficiently high.Furthermore,the tapered WAG flooding strategy proves to be profitable for enhanced oil recovery,as compared to a WAG ratio of 0.5:1,although it may not be as effective for CO_(2) sequestration. 展开更多
关键词 Residual oil zone WAG injection Carbon sequestration Enhanced oil recovery Injection strategies
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涠洲12-1油田天然气-水控制气窜实验研究 被引量:2
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作者 魏峰 李跃林 +3 位作者 马帅 王丹翎 策旭瑞 郑冰洋 《重庆科技学院学报(自然科学版)》 CAS 2021年第2期12-15,共4页
针对涠洲12-1油田涠四段油藏注天然气开发中气油比快速上升、气窜现象严重等问题,通过实验研究天然气-水控制气窜的效果及其驱替机理。利用细管装置测定原油的最小混相压力,对比天然气驱与天然气-水交替驱的实验效果;同时,利用可视化平... 针对涠洲12-1油田涠四段油藏注天然气开发中气油比快速上升、气窜现象严重等问题,通过实验研究天然气-水控制气窜的效果及其驱替机理。利用细管装置测定原油的最小混相压力,对比天然气驱与天然气-水交替驱的实验效果;同时,利用可视化平面模型分析驱替机理及剩余油分布特征。研究结果表明:该油田天然气驱混相压力为36.35 MPa,属于非混相驱替,采用天然气-水交替驱的方式可以有效减缓气油比上升速度,增加驱油效率。 展开更多
关键词 涠洲油田 天然气驱 气窜 混相程度 水气交替WAG技术 微观机理
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The crisis of representation in the postmodern era: On Barry Levinson's film Wag the Dog
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作者 张佳祺 《海外英语》 2014年第15期188-189,共2页
Barry Levinson's film Wag the Dog(1997) is concerned with the technological transformation of American culture in the postmodernism which is isomorphic with the media culture of American society in the late twenti... Barry Levinson's film Wag the Dog(1997) is concerned with the technological transformation of American culture in the postmodernism which is isomorphic with the media culture of American society in the late twentieth century. By exploring three dualities illustrated in the film,this paper aims to show the insecure and uncertain categories of these oppositions under the dominant phenomena of this period: the media,so as to bring about the public's ability to discern the postmodern world as well as a new ways of thinking and living. 展开更多
关键词 WAG the DOG Jean BAUDRILLARD REPRESENTATION dichot
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非常规EOR方案增加了普鲁德霍湾WAG开采程度较高井网的采油量
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《大庆石油地质与开发》 CAS CSCD 北大核心 2007年第5期105-105,共1页
1987年在普鲁德霍湾油田实施了大规模混相WAG项目。由于井网开采程度较高并且EOR效果减小,原来的井网不再吸收混相注入剂(MI)。现在通过用水平侧钻井将MI注入现有常规WAG井网(这些井网含有大量剩余油)内的不同位置,使普鲁德霍湾... 1987年在普鲁德霍湾油田实施了大规模混相WAG项目。由于井网开采程度较高并且EOR效果减小,原来的井网不再吸收混相注入剂(MI)。现在通过用水平侧钻井将MI注入现有常规WAG井网(这些井网含有大量剩余油)内的不同位置,使普鲁德霍湾油田水驱地区重力控制的东部(集油站2(FS2))EOR项目恢复活力。 展开更多
关键词 普鲁德霍湾油田 EOR项目 开采程度 WAG 井网 采油量 再吸收 剩余油
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A laboratory study of hot WAG injection into fractured and conventional sand packs
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作者 M J Dorostkar A Mohebbi +1 位作者 A Sarrafi A Soltani 《Petroleum Science》 SCIE CAS CSCD 2009年第4期400-404,共5页
Gas injection is the second largest enhanced oil recovery process, next only to the thermal method used in heavy oil fields. To increase the extent of the reservoir contacted by the injected gas, the gas is generally ... Gas injection is the second largest enhanced oil recovery process, next only to the thermal method used in heavy oil fields. To increase the extent of the reservoir contacted by the injected gas, the gas is generally injected intermittently with water. This mode of injection is called water-alternating-gas (WAG). This study deals with a new immiscible water alternating gas (IWAG) EOR technique, “hot IWAG” which includes combination of thermal, solvent and sweep techniques. In the proposed method CO2 will be superheated above the reservoir temperature and instead of normal temperature water, hot water will be used. Hot CO2 and hot water will be alternatively injected into the sand packs. A laboratory test was conducted on the fractured and conventional sand packs. Slugs of water and CO2 with a low and constant rate were injected into the sand packs alternatively; slug size was 0.05 PV. Recovery from each sand pack was monitored and after that hot water and hot CO2 were injected alternatively under the same conditions and increased oil recovery from each sand pack and breakthrough were measured. Experimental results showed that the injection of hot WAG could significantly recover residual oil after WAG injection in conventional and fractured sand packs. 展开更多
关键词 Hot water-alternating-gas (WAG) enhanced oil recovery (EOR) fractured sand pack conventional sand pack gas injection
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气辅助重力泄油工艺提高轻油采收率的研究
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作者 金佩强 《大庆石油地质与开发》 CAS CSCD 北大核心 2005年第3期65-65,共1页
关键词 采收率 重力泄油 工艺 轻油 重力分离 含水饱和度 WAG 自然现象 注气 EOR 油流动 矿场 动态
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Social Deprivation of Newborn Rats Modifies Exploratory and Defensive Behavior at Mature Age
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作者 Anna Yu. Shishelova Kirill S. Smirnov Vladimir V. Raevskiy 《Journal of Behavioral and Brain Science》 2019年第10期375-384,共10页
The effect of complete social deprivation in early postnatal ontogenesis on adult behavior in Wag/Rij rats with a genetic predisposition to the development of absence epilepsy was studied. From the 2nd to the 8th day ... The effect of complete social deprivation in early postnatal ontogenesis on adult behavior in Wag/Rij rats with a genetic predisposition to the development of absence epilepsy was studied. From the 2nd to the 8th day of life, a 3-hour daily isolation of the pups from the mother and siblings was performed, the control animals were handled. In adulthood, offspring behavior was tested in an elevated plus-maze, an open field, and for an ability to learn the conditioned reflex of active avoidance. In isolated earlier rats, an increase in emotional reactivity, exploratory behavior in a potentially dangerous space, the speed of learning a conditioned reflex with negative painful reinforcement, and a disturbance of the formation of a defensive reaction were revealed. It is assumed that high emotional reactivity creates the prerequisites for the development of absence epilepsy. 展开更多
关键词 ONTOGENESIS ABSENCE EPILEPSY Behavior Wag/Rij RATS
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