Unilateral spatial neglect (USN) is characterized by neglect in peripersonal and extrapersonal space, the disparity of which is unknown. We assessed these forms of neglect in a patient with USN. We promoted sight scan...Unilateral spatial neglect (USN) is characterized by neglect in peripersonal and extrapersonal space, the disparity of which is unknown. We assessed these forms of neglect in a patient with USN. We promoted sight scanning in extrapersonal space and used an eye camera to measure gaze movement. We found left-sided sight scanning in peripersonal space, but right-side-biased sight scanning in extrapersonal space. Additionally, line of sight was corrected when the patient was instructed to look left in extrapersonal space and to focus the line of sight at the center. Gaze measurement thus helped to assess disparities in spatial neglect in USN.展开更多
目的采用网状meta分析比较不同刺激方式的经颅直流电刺激(transcranial direct current stimulation,tDCS)对脑卒中后单侧忽略(unilateral spatial neglect,USN)患者的康复疗效。方法计算机检索中国知网(CNKI)、万方数据知识服务平台(Wa...目的采用网状meta分析比较不同刺激方式的经颅直流电刺激(transcranial direct current stimulation,tDCS)对脑卒中后单侧忽略(unilateral spatial neglect,USN)患者的康复疗效。方法计算机检索中国知网(CNKI)、万方数据知识服务平台(Wanfang Data)、维普网(VIP)、PubMed、Embase、Cochrane Library、Web of Science、ProQuest数据库中有关tDCS治疗USN的随机对照试验(RCT)和随机交叉实验(RCE),对照组采用假刺激或常规物理治疗,试验组为不同刺激方式的tDCS治疗,检索时间为建库至2024年5月。由两名研究员对文献进行筛选及数据的提取,采用RevMen 5.3以及Stata 14.0软件进行数据分析。结果最终纳入11篇文献,共462例患者。结果显示:多靶点刺激、阳极刺激以及阴极刺激对于提高USN患者的二等分线段测试(LBT)、星形消去测试(SCT)评分均高于对照组,阳极刺激和多靶点刺激对USN患者行为忽略测试(BIT)评分较假刺激改善明显。不同措施改善USN患者LBT评分的累积排序概率曲线下面积(SUCRA)排序结果显示:多靶点刺激(84.4%)>阳极刺激(82.4%)>阴极刺激(77.8%)>双通道刺激(76.3%)>假刺激(52.5%)>双通道刺激联合物理治疗(30.3%)>阳极联合物理治疗(22.7%)>多靶点刺激联合物理治疗(17.9%)>物理治疗(5.8%),提高SCT评分的SUCRA排序结果显示:多靶点刺激(67.1%)>阳极刺激(66.7%)>双通道刺激(56.0%)>阳极刺激联合物理治疗(47.7%)>阴极刺激(43.2%)>假刺激(41.6%)>多靶点刺激联合物理治疗(27.7%),降低BIT评分的SUCRA排序结果显示:多靶点刺激(99.7%)>阳极刺激联合物理治疗(61.1%)>多靶点刺激联合物理治疗(59.8%)>阳极刺激(59.4%)>假刺激(20.0%)>阴极刺激联合物理治疗(0.0%)。结论现有证据表明,在假刺激及常规对照的基础上,多靶点刺激和阳极刺激改善脑卒中患者USN的效果优于阴极刺激以及各种刺激联合物理治疗。受所纳入的试验的数量和质量限制,上述结果仍需谨慎采用,未来还需要引用更多更高质量的研究进一步验证。展开更多
文摘Unilateral spatial neglect (USN) is characterized by neglect in peripersonal and extrapersonal space, the disparity of which is unknown. We assessed these forms of neglect in a patient with USN. We promoted sight scanning in extrapersonal space and used an eye camera to measure gaze movement. We found left-sided sight scanning in peripersonal space, but right-side-biased sight scanning in extrapersonal space. Additionally, line of sight was corrected when the patient was instructed to look left in extrapersonal space and to focus the line of sight at the center. Gaze measurement thus helped to assess disparities in spatial neglect in USN.
文摘目的采用网状meta分析比较不同刺激方式的经颅直流电刺激(transcranial direct current stimulation,tDCS)对脑卒中后单侧忽略(unilateral spatial neglect,USN)患者的康复疗效。方法计算机检索中国知网(CNKI)、万方数据知识服务平台(Wanfang Data)、维普网(VIP)、PubMed、Embase、Cochrane Library、Web of Science、ProQuest数据库中有关tDCS治疗USN的随机对照试验(RCT)和随机交叉实验(RCE),对照组采用假刺激或常规物理治疗,试验组为不同刺激方式的tDCS治疗,检索时间为建库至2024年5月。由两名研究员对文献进行筛选及数据的提取,采用RevMen 5.3以及Stata 14.0软件进行数据分析。结果最终纳入11篇文献,共462例患者。结果显示:多靶点刺激、阳极刺激以及阴极刺激对于提高USN患者的二等分线段测试(LBT)、星形消去测试(SCT)评分均高于对照组,阳极刺激和多靶点刺激对USN患者行为忽略测试(BIT)评分较假刺激改善明显。不同措施改善USN患者LBT评分的累积排序概率曲线下面积(SUCRA)排序结果显示:多靶点刺激(84.4%)>阳极刺激(82.4%)>阴极刺激(77.8%)>双通道刺激(76.3%)>假刺激(52.5%)>双通道刺激联合物理治疗(30.3%)>阳极联合物理治疗(22.7%)>多靶点刺激联合物理治疗(17.9%)>物理治疗(5.8%),提高SCT评分的SUCRA排序结果显示:多靶点刺激(67.1%)>阳极刺激(66.7%)>双通道刺激(56.0%)>阳极刺激联合物理治疗(47.7%)>阴极刺激(43.2%)>假刺激(41.6%)>多靶点刺激联合物理治疗(27.7%),降低BIT评分的SUCRA排序结果显示:多靶点刺激(99.7%)>阳极刺激联合物理治疗(61.1%)>多靶点刺激联合物理治疗(59.8%)>阳极刺激(59.4%)>假刺激(20.0%)>阴极刺激联合物理治疗(0.0%)。结论现有证据表明,在假刺激及常规对照的基础上,多靶点刺激和阳极刺激改善脑卒中患者USN的效果优于阴极刺激以及各种刺激联合物理治疗。受所纳入的试验的数量和质量限制,上述结果仍需谨慎采用,未来还需要引用更多更高质量的研究进一步验证。
