Translation regulation is an important layer of gene expression:Generation of genome-wide expression datasets at multi-omics levels in spatial,temporal,and cell-type resolution is essential for deciphering brain compl...Translation regulation is an important layer of gene expression:Generation of genome-wide expression datasets at multi-omics levels in spatial,temporal,and cell-type resolution is essential for deciphering brain complexity.Regulation of gene expression is a highly dynamic process aiming at the production of precise levels of gene products to guarantee optimal cellular function,in response to physiological cues.Speedy advances in next-generation sequencing enabled the understanding of epigenomic and transcriptomic dynamic landscapes of different brain regions along development,aging,and disease progression.However,the correlation of the“transcriptome”with protein levels is poor because numerous mRNAs are subjected to manipulation of their translation efficiency,to warrant a favorable result under certain conditions.Hence,it is widely accepted that regulation at the translation level is a vital layer of gene expression.Quantification of actively translated mRNA populations(i.e.,“translatome”)is a more reliable predictor of the“proteome”(Wang et al.,2020).展开更多
Preserving formal style in neural machine translation (NMT) is essential, yet often overlooked as an optimization objective of the training processes. This oversight can lead to translations that, though accurate, lac...Preserving formal style in neural machine translation (NMT) is essential, yet often overlooked as an optimization objective of the training processes. This oversight can lead to translations that, though accurate, lack formality. In this paper, we propose how to improve NMT formality with large language models (LLMs), which combines the style transfer and evaluation capabilities of an LLM and the high-quality translation generation ability of NMT models to improve NMT formality. The proposed method (namely INMTF) encompasses two approaches. The first involves a revision approach using an LLM to revise the NMT-generated translation, ensuring a formal translation style. The second approach employs an LLM as a reward model for scoring translation formality, and then uses reinforcement learning algorithms to fine-tune the NMT model to maximize the reward score, thereby enhancing the formality of the generated translations. Considering the substantial parameter size of LLMs, we also explore methods to reduce the computational cost of INMTF. Experimental results demonstrate that INMTF significantly outperforms baselines in terms of translation formality and translation quality, with an improvement of +9.19 style accuracy points in the German-to-English task and +2.16 COMET score in the Russian-to-English task. Furthermore, our work demonstrates the potential of integrating LLMs within NMT frameworks to bridge the gap between NMT outputs and the formality required in various real-world translation scenarios.展开更多
This study delves into the complexities of cultural imagery transmission in translation,with a particular focus on literary and poetic works.Through a meticulous analysis of the transfer and transformation of cultural...This study delves into the complexities of cultural imagery transmission in translation,with a particular focus on literary and poetic works.Through a meticulous analysis of the transfer and transformation of cultural imagery—manifested in symbols,metaphors,and idioms—this research addresses critical questions regarding the preservation of source-language cultural imagery and its implications for target-language readers'comprehension.By conducting detailed case studies of the translation of Chinese classical poetry,specifically the works of Li Bai and Du Fu,and the Indian epic Mahabharata,this study not only uncovers the intricate nature of cultural imagery transmission but also proposes practical translation strategies.The research aims to advance the field of translation studies and foster more effective cross-cultural literary exchange.展开更多
The lysosomal enzyme β-glucocerebrosidase(GCase) belongs to the family of glycosidases and hydrolyses the glycosphingolipid glucosylceramide(GluCer) into glucose and ceramide. The enzyme is of central importance for ...The lysosomal enzyme β-glucocerebrosidase(GCase) belongs to the family of glycosidases and hydrolyses the glycosphingolipid glucosylceramide(GluCer) into glucose and ceramide. The enzyme is of central importance for two pathologies:(1) the lysosomal storage disorder Gaucher's disease(GD) and(2) the neurodegenerative disorder Parkinson's disease(PD).展开更多
Nanomedicines have revolutionized disease prevention,diagnosis,and treatment.Since the approval of Liposomal doxorubicin(Doxil)in 1995,various nanomedicines have been successfully developed1.Specifically,the COVID-19 ...Nanomedicines have revolutionized disease prevention,diagnosis,and treatment.Since the approval of Liposomal doxorubicin(Doxil)in 1995,various nanomedicines have been successfully developed1.Specifically,the COVID-19 pandemic highlighted the significance of nanomedicines,as lipid nanoparticles facilitated the mRNA vaccines success,thereby remarkable accelerating the development of RNA-drugs2,3.展开更多
This article centers on The Call of the Wild,an English novel by American author Jack London,alongside two Chinese translations by Dajie Liu and Menglin Zhang,and Rongyue Liu.Seventy sentences containing motion events...This article centers on The Call of the Wild,an English novel by American author Jack London,alongside two Chinese translations by Dajie Liu and Menglin Zhang,and Rongyue Liu.Seventy sentences containing motion events and their corresponding translations were randomly selected for analysis.The study focuses on the primary elements of motion events-manner,path,and ground-and examines their Chinese translations through the lens of Skopos theory.Skopos theory emphasizes whether translators can adopt appropriate translation strategies according to various contextual factors during the translation process.Compared to verb-framed languages,satellite-framed languages possess a richer vocabulary for manner verbs,express more detailed manner information,use more satellite words to indicate paths,and incorporate more background information.Verb-framed languages,by contrast,typically express manner information only when necessary and tend to include less background information.The analysis reveals that both Chinese translations embody the core principle of Skopos theory:translation strategies are determined by their purpose.To fulfill the novel’s translation objectives,the translators adeptly adjust their strategies for motion event components based on different contextual needs.It is noted that the Chinese translations do not fully retain the characteristics of English as a typical satellite-framed language.This observation aligns with Skopos theory’s purpose-oriented approach,which prioritizes translation goals over strict adherence to source text characteristics.展开更多
This paper mainly discusses the innovative teaching mode of translation for English Majors under the guidance of OBE education philosophy.Firstly,by analyzing the current situation of translation teaching for English ...This paper mainly discusses the innovative teaching mode of translation for English Majors under the guidance of OBE education philosophy.Firstly,by analyzing the current situation of translation teaching for English majors,this paper points out the main problems,and combined with the OBE education concept,through optimizing the top-level design,updating the teaching content,improving the teaching methods,and scientifically using the evaluation methods,constructs a student-centered and outcome-oriented teaching mode.It is hoped that this study can improve students’translation ability and comprehensive quality,and provide a useful reference for the reform of translation teaching for English majors.展开更多
Prof.Jiang Lin's recent book,Breaking Free:Liang Qchao's"Ungttred Translation"and Its Legagy,paved the way for translation history studies in a people-centered framework.This would allow scholars to ...Prof.Jiang Lin's recent book,Breaking Free:Liang Qchao's"Ungttred Translation"and Its Legagy,paved the way for translation history studies in a people-centered framework.This would allow scholars to gain not only knowledge about who Liang Qichao is and why he developed his ufetered translation strategy but also a lens into the interaction between the figure(conscious and unconscious motivations)and the socio-cultural political environment at the turn of traditional and modern China about a century back.The timely and relevant monograph can inspire more research to break down a binary mode of"original-target",and introduce a triad of"original target-self"to translators with their own personal background,mentality,practice,proclivity,stance,etc.,and historical context in which they were situated.‘That will break.a new path involving the freedom of words,translators’selves along with their conscious/unconscious motivations,and even the"in-betweenness"of the scholar and his/her target(i.e.,translators)in studies to come.展开更多
National Fire codes,mandated by government authorities to tackle technical challenges in fire prevention and control,establish fundamental standards for construction practices.International collaboration in fire prote...National Fire codes,mandated by government authorities to tackle technical challenges in fire prevention and control,establish fundamental standards for construction practices.International collaboration in fire protection technologies has opened avenues for China to access a wealth of documents and codes,which are crucial in crafting regulations and developing a robust,scientific framework for fire code formulation.However,the translation of these codes into Chinese has been inadequate,thereby diminishing the benefits of technological exchange and collaborative learning.This underscores the necessity for comprehensive research into code translation,striving for higher-quality translations guided by established translation theories.In this study,we translated the initial segment of the NFPA 1 Fire Code into Chinese and examined both the source text and target text through the lens of Translation Shift Theory,a concept introduced by Catford.The conclusion culminated in identifying four key shifts across various linguistic levels:lexis,sentences,and groups,to ensure an accurate and precise translation of fire codes.This study offers a through and lucid explanation of how the translator integrates Catford’s theories to solve technical challenges in NFPA 1 Fire Code translation,and establish essential standards for construction translation practices.展开更多
This study systematically examines the strategies essential for enhancing the global presence and influence of Chinese literature through translation.It begins by elucidating the significance of disseminating Chinese ...This study systematically examines the strategies essential for enhancing the global presence and influence of Chinese literature through translation.It begins by elucidating the significance of disseminating Chinese literature on a global scale,emphasizing its role in fostering cultural exchange,mutual understanding,and cross-cultural dialogue.Subsequently,the research provides a comprehensive analysis of the current state of Chinese literature's international outreach,highlighting both its achievements and the multifaceted challenges encountered during the translation process.By exploring diverse translation strategies—including domestication,foreignization,and cultural adaptation—this paper offers practical and theoretically grounded recommendations for improving the global reception of Chinese literary works.Through detailed case studies of prominent Chinese texts,it demonstrates how the judicious application of translation strategies can effectively convey the richness and cultural nuances of Chinese literature to international audiences.展开更多
Chinese traditional decorative patterns are a unique humanistic art paradigm with oriental poetic charm that has emerged in the development process of Chinese decorative art.They express the aesthetic trends and aesth...Chinese traditional decorative patterns are a unique humanistic art paradigm with oriental poetic charm that has emerged in the development process of Chinese decorative art.They express the aesthetic trends and aesthetic practices of Chinese decorative art.Based on the understanding of the three characteristics of the poetic connotations of Chinese traditional decorative patterns,namely"poetic semantics","harmonious aesthetic feeling",and"inclusive nature",this paper attempts to present the root aesthetic logic in the tradition of decorative art from an oriental context.It also hopes to create an internal cultural identity with poetic connotations in modern design through this exploration.展开更多
The Elongator complex is conserved in a wide range of species and plays crucial roles in diverse cellular processes.We have previously shown that the Elongator protein PoElp3 was involved in the asexual development,pa...The Elongator complex is conserved in a wide range of species and plays crucial roles in diverse cellular processes.We have previously shown that the Elongator protein PoElp3 was involved in the asexual development,pathogenicity,and autophagy of the rice blast fungus.In this study,we further revealed that PoElp3 functions via tRNA-mediated protein integrity.Phenotypic analyses revealed that overexpression of two of the tRNAs,tK(UUU)and tQ(UUG)could rescue the defects inΔPoelp3 strain.TMT-based proteomic and transcriptional analyses demonstrated that 386 proteins were down-regulated inΔPoelp3 strain compared with wild type strain Guy11,in a transcription-independent manner.Codon usage assays revealed an enrichment of Glutamine CAA-biased mRNA in the 386 proteins compared with the 70-15 genome.In addition to those reported previously,we also found that PoErp9,a sphingolipid C9-methyltransferase,was down-regulated in theΔPoelp3strain.Through an ILV2-specific integration of PoERP9-GFP into the wild type andΔPoelp3 strain,we were able to show that PoErp9 was positively regulated by PoElp3 translationally but not transcriptionally.Functional analyses revealed that PoErp9 was involved in the fungal growth,conidial development,pathogenicity,and TORrelated autophagy homeostasis in Pyricularia oryzae.Taken together,our results suggested that PoElp3 acts through the tRNA-mediated translational efficiency to regulate asexual development,pathogenicity,sphingolipid metabolism,and autophagy in the rice blast fungus.展开更多
Selenium is a crucial trace element that contributes to physiological processes in the body as selenoproteins.Selenoproteins serve as an integral role in the body in controlling the redox state of cells and protecting...Selenium is a crucial trace element that contributes to physiological processes in the body as selenoproteins.Selenoproteins serve as an integral role in the body in controlling the redox state of cells and protecting against damage induced by oxidative stress.This study aimed to investigate the effects and possible mechanism of selenium on selenoproteins expression in EA.hy926 cells induced by oxidized low density lipoprotein(oxLDL).The impact of selenium on the viability of EA.hy926 cells was detected by the methylthiazolyldiphenyltetrazolium bromide(MTT)method,and intracellular reactive oxygen species(ROS)level and mitochondrial membrane potential were assessed by fluorescent probe DCFH-DA and JC-1,respectively.RNA-seq,quantitative real-time polymerase chain reaction(qPCR),and Western blot were used to investigate the selenoprotein expression.Selenoprotein mRNA translation efficiency was analyzed by ribosome profiling(Ribo-Seq)coupled with transcriptomics.Our data showed that selenium supplementation(0.5μmol/L)significantly decreased ROS production,increased mitochondrial inner membrane potential and increased the proliferative activity of EA.hy926 cells induced by oxLDL.Moreover,The protective effects of selenium against oxLDL-induced EA.hy926 cell injury were associated with the upregulation of the expressions of selenoproteins glutathione peroxidase 1(GPX1),glutathione peroxidase 4(GPX4),and thioredoxin reductase 1(TXNRD1).Furthermore,the expressions of selenoproteins GPX1 and GPX4 were hierarchically controlled,but the expressions of selenoproteins TXNRD1 were mainly regulated by oxLDL.Finally,Ribo-Seq coupled with transcriptomics results demonstrated that the expressions of selenoproteins GPX1,GPX4,and TXNRD1 were regulated at the translation process level.These findings suggested that selenium could have preventive effects in oxLDL induced EA.hy926 cell injury by regulating the selenoprotein expression,and the selenoproteins expressions at the translation level in vascular endothelial cells need further study.展开更多
Hepatocellular carcinoma(HCC)recurrence after liver transplantation(LT)presents a significant challenge,with recurrence rates ranging from 8%to 20%globally.Current biomarkers,such as alpha-fetoprotein(AFP)and des-gamm...Hepatocellular carcinoma(HCC)recurrence after liver transplantation(LT)presents a significant challenge,with recurrence rates ranging from 8%to 20%globally.Current biomarkers,such as alpha-fetoprotein(AFP)and des-gamma-carboxy prothrombin(DCP),lack specificity,limiting their utility in risk strati-fication.YKL-40,a glycoprotein involved in extracellular matrix remodeling,hepatic stellate cell activation,and immune modulation,has emerged as a promising biomarker for post-LT surveillance.Elevated serum levels of YKL-40 are associated with advanced liver disease,tumor progression,and poorer post-LT outcomes,highlighting its potential to address gaps in early detection and personalized management of HCC recurrence.This manuscript synthesizes clinical and mechanistic evidence to evaluate YKL-40’s predictive utility in post-LT care.While preliminary findings demonstrate its specificity for liver-related pathologies,challenges remain,including assay standardization,lack of pro-spective validation,and the need to distinguish between malignant and non-malignant causes of elevated levels.Integrating YKL-40 into multi-biomarker panels with AFP and DCP could enhance predictive accuracy and enable tailored therapeutic strategies.Future research should focus on multicenter studies to validate YKL-40’s clinical utility,address confounding factors like graft rejection and systemic inflammation,and explore its role in predictive models driven by emerging technologies such as artificial intelligence.YKL-40 holds transformative potential in reshaping post-LT care through precision medicine,providing a pathway for better outcomes and improved management of high-risk LT recipients.展开更多
This study introduced Wing-tsit Chan's thoughts on the translation of Chinese philosophical concepts,analyzed the characteristics of Chinese philosophical concepts in their ways of expression,and took A Soure Book...This study introduced Wing-tsit Chan's thoughts on the translation of Chinese philosophical concepts,analyzed the characteristics of Chinese philosophical concepts in their ways of expression,and took A Soure Book of Chinese Philosoply as a case study to explore Wing tsit Chan's principles and mcthods of reproducing the inner spirit and expressive atibutes of Chinese philosophical concepts.展开更多
This article,empowered by ChatGPT and through retrieving relevant historical literature,explores how the translator Sun Yat-sen flexibly employed strategies like domestication and foreignization,as well as methods lik...This article,empowered by ChatGPT and through retrieving relevant historical literature,explores how the translator Sun Yat-sen flexibly employed strategies like domestication and foreignization,as well as methods like omission,addition,and modification in his translation of Ambulance Lectures:First Aid to the Injured.Additionally,the research highlights the use of ChatGPT as a tool to assist in the study.While ChatGPT is able to provide comprehensive knowledge quickly and proper translations,improvements are still needed in terms of image accuracy and citation generation.By providing specific context,probing for factual evidence,clarifying the reference objects,and narrowing the scope,prompts can be gradually refined for increasingly satisfactory outcomes.展开更多
Existing studies have underscored the pivotal role of N-acetyltransferase 10(NAT10) in various cancers. However, the outcomes of protein-protein interactions between NAT10 and its protein partners in head and neck squ...Existing studies have underscored the pivotal role of N-acetyltransferase 10(NAT10) in various cancers. However, the outcomes of protein-protein interactions between NAT10 and its protein partners in head and neck squamous cell carcinoma(HNSCC) remain unexplored. In this study, we identified a significant upregulation of RNA-binding protein with serine-rich domain 1(RNPS1) in HNSCC, where RNPS1 inhibits the ubiquitination degradation of NAT10 by E3 ubiquitin ligase, zinc finger SWIM domain-containing protein 6(ZSWIM6), through direct protein interaction, thereby promoting high NAT10 expression in HNSCC. This upregulated NAT10 stability mediates the enhancement of specific tRNA ac^(4)C modifications, subsequently boosting the translation process of genes involved in pathways such as IL-6 signaling, IL-8 signaling, and PTEN signaling that play roles in regulating HNSCC malignant progression, ultimately influencing the survival and prognosis of HNSCC patients. Additionally, we pioneered the development of TRMC-seq, leading to the discovery of novel t RNA-ac^(4)C modification sites, thereby providing a potent sequencing tool for tRNAac^(4)C research. Our findings expand the repertoire of tRNA ac^(4)C modifications and identify a role of tRNA ac^(4)C in the regulation of mRNA translation in HNSCC.展开更多
In the field of natural language processing(NLP),the advancement of neural machine translation has paved the way for cross-lingual research.Yet,most studies in NLP have evaluated the proposed language models on well-r...In the field of natural language processing(NLP),the advancement of neural machine translation has paved the way for cross-lingual research.Yet,most studies in NLP have evaluated the proposed language models on well-refined datasets.We investigatewhether amachine translation approach is suitable for multilingual analysis of unrefined datasets,particularly,chat messages in Twitch.In order to address it,we collected the dataset,which included 7,066,854 and 3,365,569 chat messages from English and Korean streams,respectively.We employed several machine learning classifiers and neural networks with two different types of embedding:word-sequence embedding and the final layer of a pre-trained language model.The results of the employed models indicate that the accuracy difference between English,and English to Korean was relatively high,ranging from 3%to 12%.For Korean data(Korean,and Korean to English),it ranged from 0%to 2%.Therefore,the results imply that translation from a low-resource language(e.g.,Korean)into a high-resource language(e.g.,English)shows higher performance,in contrast to vice versa.Several implications and limitations of the presented results are also discussed.For instance,we suggest the feasibility of translation from resource-poor languages for using the tools of resource-rich languages in further analysis.展开更多
The article deals with the translation of German poetry into Wolof and is based on Tamsir Annes＇s translation of German poems under the title Tdere-Woy yi/Das Buch der Lieder. My purpose in this paper is to answer th...The article deals with the translation of German poetry into Wolof and is based on Tamsir Annes＇s translation of German poems under the title Tdere-Woy yi/Das Buch der Lieder. My purpose in this paper is to answer the question of how elements of the vocabulary of sciences （literature and philosophy） as well as cultural specific items are rendered in the Wolof target text. Therefore, in this work, I explore methods and strategies of translation like borrowings, paraphrases, and analyze furthermore some differences noticeable in the translation of some poems at the cultural level. These analysis-steps enable the investigation of, contextually, the central issue of ＂cultural translatability＂ and the reception of translation of European poetry into African languages in general and German poetry into Wolof in particular. The article also focuses on the importance of the reception of German poetry in Wolof as a means of intercultural communication between German and Wolof-speaking countries but as means to develop African languages like Wolof in which the translation of the selected poems has been operated.展开更多
基金funded by the Israel Science Foundation(grants No.1036/12 and 1228/20)(to OES).
文摘Translation regulation is an important layer of gene expression:Generation of genome-wide expression datasets at multi-omics levels in spatial,temporal,and cell-type resolution is essential for deciphering brain complexity.Regulation of gene expression is a highly dynamic process aiming at the production of precise levels of gene products to guarantee optimal cellular function,in response to physiological cues.Speedy advances in next-generation sequencing enabled the understanding of epigenomic and transcriptomic dynamic landscapes of different brain regions along development,aging,and disease progression.However,the correlation of the“transcriptome”with protein levels is poor because numerous mRNAs are subjected to manipulation of their translation efficiency,to warrant a favorable result under certain conditions.Hence,it is widely accepted that regulation at the translation level is a vital layer of gene expression.Quantification of actively translated mRNA populations(i.e.,“translatome”)is a more reliable predictor of the“proteome”(Wang et al.,2020).
文摘Preserving formal style in neural machine translation (NMT) is essential, yet often overlooked as an optimization objective of the training processes. This oversight can lead to translations that, though accurate, lack formality. In this paper, we propose how to improve NMT formality with large language models (LLMs), which combines the style transfer and evaluation capabilities of an LLM and the high-quality translation generation ability of NMT models to improve NMT formality. The proposed method (namely INMTF) encompasses two approaches. The first involves a revision approach using an LLM to revise the NMT-generated translation, ensuring a formal translation style. The second approach employs an LLM as a reward model for scoring translation formality, and then uses reinforcement learning algorithms to fine-tune the NMT model to maximize the reward score, thereby enhancing the formality of the generated translations. Considering the substantial parameter size of LLMs, we also explore methods to reduce the computational cost of INMTF. Experimental results demonstrate that INMTF significantly outperforms baselines in terms of translation formality and translation quality, with an improvement of +9.19 style accuracy points in the German-to-English task and +2.16 COMET score in the Russian-to-English task. Furthermore, our work demonstrates the potential of integrating LLMs within NMT frameworks to bridge the gap between NMT outputs and the formality required in various real-world translation scenarios.
文摘This study delves into the complexities of cultural imagery transmission in translation,with a particular focus on literary and poetic works.Through a meticulous analysis of the transfer and transformation of cultural imagery—manifested in symbols,metaphors,and idioms—this research addresses critical questions regarding the preservation of source-language cultural imagery and its implications for target-language readers'comprehension.By conducting detailed case studies of the translation of Chinese classical poetry,specifically the works of Li Bai and Du Fu,and the Indian epic Mahabharata,this study not only uncovers the intricate nature of cultural imagery transmission but also proposes practical translation strategies.The research aims to advance the field of translation studies and foster more effective cross-cultural literary exchange.
基金supported by the Michael J Fox Foundation (to PA and FZ)。
文摘The lysosomal enzyme β-glucocerebrosidase(GCase) belongs to the family of glycosidases and hydrolyses the glycosphingolipid glucosylceramide(GluCer) into glucose and ceramide. The enzyme is of central importance for two pathologies:(1) the lysosomal storage disorder Gaucher's disease(GD) and(2) the neurodegenerative disorder Parkinson's disease(PD).
基金supported by the Postdoctoral Fellowship Program of CPSF(No.GZC20230333,China).
文摘Nanomedicines have revolutionized disease prevention,diagnosis,and treatment.Since the approval of Liposomal doxorubicin(Doxil)in 1995,various nanomedicines have been successfully developed1.Specifically,the COVID-19 pandemic highlighted the significance of nanomedicines,as lipid nanoparticles facilitated the mRNA vaccines success,thereby remarkable accelerating the development of RNA-drugs2,3.
基金Humanities and Social Sciences Research Project of China’s Ministry of Education(23YJCZH242)Major Humanities and Social Sciences Research Projects in Zhejiang Higher Education Institutions(2024QN069)Hangzhou Collaborative Innovation Institute of Language Services,Hangzhou City University,China。
文摘This article centers on The Call of the Wild,an English novel by American author Jack London,alongside two Chinese translations by Dajie Liu and Menglin Zhang,and Rongyue Liu.Seventy sentences containing motion events and their corresponding translations were randomly selected for analysis.The study focuses on the primary elements of motion events-manner,path,and ground-and examines their Chinese translations through the lens of Skopos theory.Skopos theory emphasizes whether translators can adopt appropriate translation strategies according to various contextual factors during the translation process.Compared to verb-framed languages,satellite-framed languages possess a richer vocabulary for manner verbs,express more detailed manner information,use more satellite words to indicate paths,and incorporate more background information.Verb-framed languages,by contrast,typically express manner information only when necessary and tend to include less background information.The analysis reveals that both Chinese translations embody the core principle of Skopos theory:translation strategies are determined by their purpose.To fulfill the novel’s translation objectives,the translators adeptly adjust their strategies for motion event components based on different contextual needs.It is noted that the Chinese translations do not fully retain the characteristics of English as a typical satellite-framed language.This observation aligns with Skopos theory’s purpose-oriented approach,which prioritizes translation goals over strict adherence to source text characteristics.
文摘This paper mainly discusses the innovative teaching mode of translation for English Majors under the guidance of OBE education philosophy.Firstly,by analyzing the current situation of translation teaching for English majors,this paper points out the main problems,and combined with the OBE education concept,through optimizing the top-level design,updating the teaching content,improving the teaching methods,and scientifically using the evaluation methods,constructs a student-centered and outcome-oriented teaching mode.It is hoped that this study can improve students’translation ability and comprehensive quality,and provide a useful reference for the reform of translation teaching for English majors.
文摘Prof.Jiang Lin's recent book,Breaking Free:Liang Qchao's"Ungttred Translation"and Its Legagy,paved the way for translation history studies in a people-centered framework.This would allow scholars to gain not only knowledge about who Liang Qichao is and why he developed his ufetered translation strategy but also a lens into the interaction between the figure(conscious and unconscious motivations)and the socio-cultural political environment at the turn of traditional and modern China about a century back.The timely and relevant monograph can inspire more research to break down a binary mode of"original-target",and introduce a triad of"original target-self"to translators with their own personal background,mentality,practice,proclivity,stance,etc.,and historical context in which they were situated.‘That will break.a new path involving the freedom of words,translators’selves along with their conscious/unconscious motivations,and even the"in-betweenness"of the scholar and his/her target(i.e.,translators)in studies to come.
基金Hangzhou Philosophy and Social Science Planning Program(24JD15)。
文摘National Fire codes,mandated by government authorities to tackle technical challenges in fire prevention and control,establish fundamental standards for construction practices.International collaboration in fire protection technologies has opened avenues for China to access a wealth of documents and codes,which are crucial in crafting regulations and developing a robust,scientific framework for fire code formulation.However,the translation of these codes into Chinese has been inadequate,thereby diminishing the benefits of technological exchange and collaborative learning.This underscores the necessity for comprehensive research into code translation,striving for higher-quality translations guided by established translation theories.In this study,we translated the initial segment of the NFPA 1 Fire Code into Chinese and examined both the source text and target text through the lens of Translation Shift Theory,a concept introduced by Catford.The conclusion culminated in identifying four key shifts across various linguistic levels:lexis,sentences,and groups,to ensure an accurate and precise translation of fire codes.This study offers a through and lucid explanation of how the translator integrates Catford’s theories to solve technical challenges in NFPA 1 Fire Code translation,and establish essential standards for construction translation practices.
文摘This study systematically examines the strategies essential for enhancing the global presence and influence of Chinese literature through translation.It begins by elucidating the significance of disseminating Chinese literature on a global scale,emphasizing its role in fostering cultural exchange,mutual understanding,and cross-cultural dialogue.Subsequently,the research provides a comprehensive analysis of the current state of Chinese literature's international outreach,highlighting both its achievements and the multifaceted challenges encountered during the translation process.By exploring diverse translation strategies—including domestication,foreignization,and cultural adaptation—this paper offers practical and theoretically grounded recommendations for improving the global reception of Chinese literary works.Through detailed case studies of prominent Chinese texts,it demonstrates how the judicious application of translation strategies can effectively convey the richness and cultural nuances of Chinese literature to international audiences.
基金Research Project of the Korea Institute for Humanities and Social Sciences(No.2023KIHSSB009)。
文摘Chinese traditional decorative patterns are a unique humanistic art paradigm with oriental poetic charm that has emerged in the development process of Chinese decorative art.They express the aesthetic trends and aesthetic practices of Chinese decorative art.Based on the understanding of the three characteristics of the poetic connotations of Chinese traditional decorative patterns,namely"poetic semantics","harmonious aesthetic feeling",and"inclusive nature",this paper attempts to present the root aesthetic logic in the tradition of decorative art from an oriental context.It also hopes to create an internal cultural identity with poetic connotations in modern design through this exploration.
基金supported by National Natural Science Foundation of China(32172365 and 32272513)the Central Guidance on Local Science and Technology Development Fund of Fujian Province,China(2022L3088)the Innovative Research Funding of Fujian Agriculture and Forestry University,China(CXZX2020153D)。
文摘The Elongator complex is conserved in a wide range of species and plays crucial roles in diverse cellular processes.We have previously shown that the Elongator protein PoElp3 was involved in the asexual development,pathogenicity,and autophagy of the rice blast fungus.In this study,we further revealed that PoElp3 functions via tRNA-mediated protein integrity.Phenotypic analyses revealed that overexpression of two of the tRNAs,tK(UUU)and tQ(UUG)could rescue the defects inΔPoelp3 strain.TMT-based proteomic and transcriptional analyses demonstrated that 386 proteins were down-regulated inΔPoelp3 strain compared with wild type strain Guy11,in a transcription-independent manner.Codon usage assays revealed an enrichment of Glutamine CAA-biased mRNA in the 386 proteins compared with the 70-15 genome.In addition to those reported previously,we also found that PoErp9,a sphingolipid C9-methyltransferase,was down-regulated in theΔPoelp3strain.Through an ILV2-specific integration of PoERP9-GFP into the wild type andΔPoelp3 strain,we were able to show that PoErp9 was positively regulated by PoElp3 translationally but not transcriptionally.Functional analyses revealed that PoErp9 was involved in the fungal growth,conidial development,pathogenicity,and TORrelated autophagy homeostasis in Pyricularia oryzae.Taken together,our results suggested that PoElp3 acts through the tRNA-mediated translational efficiency to regulate asexual development,pathogenicity,sphingolipid metabolism,and autophagy in the rice blast fungus.
基金supported by grants from the National Natural Science Foundation of China(NSFC,81960588)the Ningxia Natural Science Foundation(2020AAC03146)support from the Ningxia Medical University。
文摘Selenium is a crucial trace element that contributes to physiological processes in the body as selenoproteins.Selenoproteins serve as an integral role in the body in controlling the redox state of cells and protecting against damage induced by oxidative stress.This study aimed to investigate the effects and possible mechanism of selenium on selenoproteins expression in EA.hy926 cells induced by oxidized low density lipoprotein(oxLDL).The impact of selenium on the viability of EA.hy926 cells was detected by the methylthiazolyldiphenyltetrazolium bromide(MTT)method,and intracellular reactive oxygen species(ROS)level and mitochondrial membrane potential were assessed by fluorescent probe DCFH-DA and JC-1,respectively.RNA-seq,quantitative real-time polymerase chain reaction(qPCR),and Western blot were used to investigate the selenoprotein expression.Selenoprotein mRNA translation efficiency was analyzed by ribosome profiling(Ribo-Seq)coupled with transcriptomics.Our data showed that selenium supplementation(0.5μmol/L)significantly decreased ROS production,increased mitochondrial inner membrane potential and increased the proliferative activity of EA.hy926 cells induced by oxLDL.Moreover,The protective effects of selenium against oxLDL-induced EA.hy926 cell injury were associated with the upregulation of the expressions of selenoproteins glutathione peroxidase 1(GPX1),glutathione peroxidase 4(GPX4),and thioredoxin reductase 1(TXNRD1).Furthermore,the expressions of selenoproteins GPX1 and GPX4 were hierarchically controlled,but the expressions of selenoproteins TXNRD1 were mainly regulated by oxLDL.Finally,Ribo-Seq coupled with transcriptomics results demonstrated that the expressions of selenoproteins GPX1,GPX4,and TXNRD1 were regulated at the translation process level.These findings suggested that selenium could have preventive effects in oxLDL induced EA.hy926 cell injury by regulating the selenoprotein expression,and the selenoproteins expressions at the translation level in vascular endothelial cells need further study.
文摘Hepatocellular carcinoma(HCC)recurrence after liver transplantation(LT)presents a significant challenge,with recurrence rates ranging from 8%to 20%globally.Current biomarkers,such as alpha-fetoprotein(AFP)and des-gamma-carboxy prothrombin(DCP),lack specificity,limiting their utility in risk strati-fication.YKL-40,a glycoprotein involved in extracellular matrix remodeling,hepatic stellate cell activation,and immune modulation,has emerged as a promising biomarker for post-LT surveillance.Elevated serum levels of YKL-40 are associated with advanced liver disease,tumor progression,and poorer post-LT outcomes,highlighting its potential to address gaps in early detection and personalized management of HCC recurrence.This manuscript synthesizes clinical and mechanistic evidence to evaluate YKL-40’s predictive utility in post-LT care.While preliminary findings demonstrate its specificity for liver-related pathologies,challenges remain,including assay standardization,lack of pro-spective validation,and the need to distinguish between malignant and non-malignant causes of elevated levels.Integrating YKL-40 into multi-biomarker panels with AFP and DCP could enhance predictive accuracy and enable tailored therapeutic strategies.Future research should focus on multicenter studies to validate YKL-40’s clinical utility,address confounding factors like graft rejection and systemic inflammation,and explore its role in predictive models driven by emerging technologies such as artificial intelligence.YKL-40 holds transformative potential in reshaping post-LT care through precision medicine,providing a pathway for better outcomes and improved management of high-risk LT recipients.
文摘This study introduced Wing-tsit Chan's thoughts on the translation of Chinese philosophical concepts,analyzed the characteristics of Chinese philosophical concepts in their ways of expression,and took A Soure Book of Chinese Philosoply as a case study to explore Wing tsit Chan's principles and mcthods of reproducing the inner spirit and expressive atibutes of Chinese philosophical concepts.
基金Research on AI Empowered Bilingual Language Asset Management and English Language Teaching Reform(24JG29)Research on the Digital Empowerment in Business English Major Reform and Innovation in the Context of Language Services(National Higher Education Institutions 202412583HN)Chinese Academic Translation Project of“C-E Translation of The Transformation of Rural China”(21WSHB004)。
文摘This article,empowered by ChatGPT and through retrieving relevant historical literature,explores how the translator Sun Yat-sen flexibly employed strategies like domestication and foreignization,as well as methods like omission,addition,and modification in his translation of Ambulance Lectures:First Aid to the Injured.Additionally,the research highlights the use of ChatGPT as a tool to assist in the study.While ChatGPT is able to provide comprehensive knowledge quickly and proper translations,improvements are still needed in terms of image accuracy and citation generation.By providing specific context,probing for factual evidence,clarifying the reference objects,and narrowing the scope,prompts can be gradually refined for increasingly satisfactory outcomes.
基金supported by the National Natural Science Foundation of China(82173362 and 81872409)the Guangdong Basic and Applied Basic Research Foundation(2019A1515110110)。
文摘Existing studies have underscored the pivotal role of N-acetyltransferase 10(NAT10) in various cancers. However, the outcomes of protein-protein interactions between NAT10 and its protein partners in head and neck squamous cell carcinoma(HNSCC) remain unexplored. In this study, we identified a significant upregulation of RNA-binding protein with serine-rich domain 1(RNPS1) in HNSCC, where RNPS1 inhibits the ubiquitination degradation of NAT10 by E3 ubiquitin ligase, zinc finger SWIM domain-containing protein 6(ZSWIM6), through direct protein interaction, thereby promoting high NAT10 expression in HNSCC. This upregulated NAT10 stability mediates the enhancement of specific tRNA ac^(4)C modifications, subsequently boosting the translation process of genes involved in pathways such as IL-6 signaling, IL-8 signaling, and PTEN signaling that play roles in regulating HNSCC malignant progression, ultimately influencing the survival and prognosis of HNSCC patients. Additionally, we pioneered the development of TRMC-seq, leading to the discovery of novel t RNA-ac^(4)C modification sites, thereby providing a potent sequencing tool for tRNAac^(4)C research. Our findings expand the repertoire of tRNA ac^(4)C modifications and identify a role of tRNA ac^(4)C in the regulation of mRNA translation in HNSCC.
基金This work was supported by Institute of Information&communications Technology Planning&Evaluation(IITP)grant funded by the Korea government(MSIT)(No.2021-0-00358,AI·Big data based Cyber Security Orchestration and Automated Response Technology Development).
文摘In the field of natural language processing(NLP),the advancement of neural machine translation has paved the way for cross-lingual research.Yet,most studies in NLP have evaluated the proposed language models on well-refined datasets.We investigatewhether amachine translation approach is suitable for multilingual analysis of unrefined datasets,particularly,chat messages in Twitch.In order to address it,we collected the dataset,which included 7,066,854 and 3,365,569 chat messages from English and Korean streams,respectively.We employed several machine learning classifiers and neural networks with two different types of embedding:word-sequence embedding and the final layer of a pre-trained language model.The results of the employed models indicate that the accuracy difference between English,and English to Korean was relatively high,ranging from 3%to 12%.For Korean data(Korean,and Korean to English),it ranged from 0%to 2%.Therefore,the results imply that translation from a low-resource language(e.g.,Korean)into a high-resource language(e.g.,English)shows higher performance,in contrast to vice versa.Several implications and limitations of the presented results are also discussed.For instance,we suggest the feasibility of translation from resource-poor languages for using the tools of resource-rich languages in further analysis.
文摘The article deals with the translation of German poetry into Wolof and is based on Tamsir Annes＇s translation of German poems under the title Tdere-Woy yi/Das Buch der Lieder. My purpose in this paper is to answer the question of how elements of the vocabulary of sciences （literature and philosophy） as well as cultural specific items are rendered in the Wolof target text. Therefore, in this work, I explore methods and strategies of translation like borrowings, paraphrases, and analyze furthermore some differences noticeable in the translation of some poems at the cultural level. These analysis-steps enable the investigation of, contextually, the central issue of ＂cultural translatability＂ and the reception of translation of European poetry into African languages in general and German poetry into Wolof in particular. The article also focuses on the importance of the reception of German poetry in Wolof as a means of intercultural communication between German and Wolof-speaking countries but as means to develop African languages like Wolof in which the translation of the selected poems has been operated.
