首次报道了中国兰科新记录属三角兰属(Trias),并对该属及该属新种疣花三角兰(T.verrucosa Z.J.Liu,L.J.Chen et S.P.Lei)进行了描述与讨论。三角兰属含19种,分布于自印度的阿萨姆经缅甸向东南扩展至印度尼西亚与澳大利亚,向西南延伸至...首次报道了中国兰科新记录属三角兰属(Trias),并对该属及该属新种疣花三角兰(T.verrucosa Z.J.Liu,L.J.Chen et S.P.Lei)进行了描述与讨论。三角兰属含19种,分布于自印度的阿萨姆经缅甸向东南扩展至印度尼西亚与澳大利亚,向西南延伸至印度德干高原。它在云南西部的发现进一步表明了该地区与热带亚洲在植物地理学上的亲密关系。新种生于林下较阴蔽的石上,对其物候学与开花生物学特征的观察,发现该物种有大量世代重叠的克隆分株,未见结实的植株,克隆繁殖的发生与分株是否开花无关。花期自4月初至5月初,花在植株或花序上的开放毫无规律,而且单花的花期较短,仅有4～5d,未发现有结实的花。交配系统检测,人工自花传粉和异花传粉的花未见有结实。由于该植物的花期常处于雨季来临之前,此时干燥,风力大,低温和弱光的生态条件对于植物的开花、传粉、结实显然是不利的。缩短开花时间和不结实可避免植株的能量在不利环境的无效消耗,将有限的能量用于其较为有效的无性繁殖,增加了在不可预测环境中繁衍的机会,以保障繁殖的成功。它的P/O(花粉/胚珠)值为187.4±22.4,显然是与它的花粉粘合成坚硬块状可在传粉中的高效利用有关,表明该物种仍然保留有性繁殖的特性。该种植物所采取强化无性繁殖,弱化有性繁殖生殖策略是对该地区较为恶劣生态条件的适应,可能正是由于这个原因,疣花三角兰能够在远离其同属近亲的地方生存下来。展开更多
Background Recombinant human GH(rhGH)was first approved to treat children with growth hormone deficiency(GHD)by Food and Drug Administration(FDA)in the United States in 1985.The indications subsequently expanded to gr...Background Recombinant human GH(rhGH)was first approved to treat children with growth hormone deficiency(GHD)by Food and Drug Administration(FDA)in the United States in 1985.The indications subsequently expanded to growth failure secondary to chronic renal failure,Turner syndrome,Prader‒Willi syndrome,small for gestational age(SGA)without catch-up growth,idiopathic short stature(ISS),SHOX deficiency,Noonan syndrome and so on[1].The efficacy and the safety of rhGH have been proven in randomized controlled trials(RCTs),which are considered the highest level of evidences in clinical practice.However,due to the strict criteria and short observational time,RCTs could not fully reflect the reality of rhGH,especially in terms of safety[2].展开更多
The Lower Triassic Feixianguan （飞仙关） Formation oolitic shoal reservoir in the Sichuan （四川） basin （Southwest China） is currently an exploration and research highlight in China. The reservoir is widely believ...The Lower Triassic Feixianguan （飞仙关） Formation oolitic shoal reservoir in the Sichuan （四川） basin （Southwest China） is currently an exploration and research highlight in China. The reservoir is widely believed to be formed mainly by burial dissolution and/or dolomitization on the basis of primary intergranular pores. In this study, through a comprehensive geological study on the whole basin, the dissolution and dolomitization are suggested not to be the fundamental factor of reservoir formation and there thus may be a possible new fundamental mechanism-the preservation of primary intergranular pores, i.e., the retention diagenesis. Based on this, a complex and multi-stage reservoir evolution and formation model is proposed. In the model, the depositional environment is the basis of reservoir initial formation. Subsequently, early compaction and shallow burial cementation result in the primary reservoir differentiation. Then, multi-stage burial dissolution alters and adjusts the reservoir. Because the last stage gaseous hydrocarbons have little diagenetic impact, the reservoir is formed finally. Therefore, this study presents a possible new fundamental mechanism and evolution model for the reservoir formation. The results can be applied in the regional reservoir predication and shaping exploration strategies, and provide reference for the study of shoal reservoirs in other areas.展开更多
BACKGROUND： Some research exists on the effect of non-pharmacological approaches for labor pain relief However, there is limited information about effectiveness of breathing exercises in pregnant women to reduce mate...BACKGROUND： Some research exists on the effect of non-pharmacological approaches for labor pain relief However, there is limited information about effectiveness of breathing exercises in pregnant women to reduce maternal pain during labor. OBJECTIVE： To determine whether breathing exercises for pregnant women during the second stage of labor have beneficial effects on maternal pain, duration of labor, and the first-minute Appearance, Pulse, Grimace, Activity and Respiration （APGAR） scores. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS： This randomized clinical trial involved 250 pregnant women, who were randomly divided into two groups： intervention group （IG; n = 125） and control group （CG; n = 125）. IG received one session breathing exercise training and performed breathing exercises during the second stage of labor versus the CG that did not receive any breathing exercise training. MAIN OUTCOME MEASURES： The effects of breathing exercises on maternal pain were determined by Visual Analogue Scale （VAS）, duration of the second stage of labor, and the first-minute APGAR scores. RESULTS： The mean age of the participants was （23.2 _＋ 4.2） （range： 18 to 42） years. Both IG and CG had similar baseline characteristics in terms of age, education level, occupation, and smoking （P 〉 0.05）. The mean VAS scores of IG and CG were （88.2 ＋_ 6.3） and （90.5 ＋_ 7.0）, respectively （P 〈 0.001）. The duration of the second stage of labor was （369.6 ＋ 92.0） s for IG and （440.7 ＋ 142.5） s for CG （P 〈 0.001 ）. The mean first-minute APGAR scores were （8.84 ＋ 0.50） for IG and （8.73 ＋ 0.89） for CG （P 〉 0.05）. CONCLUSION： Based on this study, breathing exercises with deep inhalation and exhalation in pregnant women are effective in reducing the perception of labor pain and shortening the duration of the second stage of delivery. Therefore, we recommend breathing exercises as an effective modality for labor pain management and shortening the duration of labor. TRIAL REGISTRATION： This study is registered on the website of ClinicalTrials.gov （www.clinicaltrials.gov） with the number of NCT03066973.展开更多
目的:观察基于名中医经验的中医辨证组方对老年慢性肾炎(CKD1-3a期)患者的有效性和安全性。方法:将84例老年慢性肾炎患者随机分成治疗组(42例)和对照组(42例)。治疗组采用西医基础联合中医辨证组方治疗;对照组仅接受西医基础治疗,疗程均...目的:观察基于名中医经验的中医辨证组方对老年慢性肾炎(CKD1-3a期)患者的有效性和安全性。方法:将84例老年慢性肾炎患者随机分成治疗组(42例)和对照组(42例)。治疗组采用西医基础联合中医辨证组方治疗;对照组仅接受西医基础治疗,疗程均为24周。观察两组治疗前后24 h尿蛋白定量(24 h UPQ)、肾小球滤过率(eGFR)等临床指标变化,以及疗效和安全性。结果:与本组基线比较,两组治疗后12、18、24周24 h UPQ均显著下降(P<0.01),且24周时治疗组优于对照组(P<0.01)。治疗组总有效率为67.57%,对照组总有效率41.67%,治疗组显著高于对照组(P<0.05)。将慢性肾脏病(CKD)3a期患者进行亚组分析提示,24周后治疗组eGFR较本组基线及同期对照组显著升高(P<0.01,P<0.05),而对照组治疗前后无显著变化。治疗组不良反应发生4例,对照组2例,两组无严重不良反应出现。结论:基于名中医经验的中医辨证组方治疗老年慢性肾炎(CKD1-3a期),可减少尿蛋白,提高临床疗效,对其中的CKD3a期患者可能具有改善eGFR作用,且安全性较好。展开更多
文摘首次报道了中国兰科新记录属三角兰属(Trias),并对该属及该属新种疣花三角兰(T.verrucosa Z.J.Liu,L.J.Chen et S.P.Lei)进行了描述与讨论。三角兰属含19种,分布于自印度的阿萨姆经缅甸向东南扩展至印度尼西亚与澳大利亚,向西南延伸至印度德干高原。它在云南西部的发现进一步表明了该地区与热带亚洲在植物地理学上的亲密关系。新种生于林下较阴蔽的石上,对其物候学与开花生物学特征的观察,发现该物种有大量世代重叠的克隆分株,未见结实的植株,克隆繁殖的发生与分株是否开花无关。花期自4月初至5月初,花在植株或花序上的开放毫无规律,而且单花的花期较短,仅有4～5d,未发现有结实的花。交配系统检测,人工自花传粉和异花传粉的花未见有结实。由于该植物的花期常处于雨季来临之前,此时干燥,风力大,低温和弱光的生态条件对于植物的开花、传粉、结实显然是不利的。缩短开花时间和不结实可避免植株的能量在不利环境的无效消耗,将有限的能量用于其较为有效的无性繁殖,增加了在不可预测环境中繁衍的机会,以保障繁殖的成功。它的P/O(花粉/胚珠)值为187.4±22.4,显然是与它的花粉粘合成坚硬块状可在传粉中的高效利用有关,表明该物种仍然保留有性繁殖的特性。该种植物所采取强化无性繁殖,弱化有性繁殖生殖策略是对该地区较为恶劣生态条件的适应,可能正是由于这个原因,疣花三角兰能够在远离其同属近亲的地方生存下来。
文摘Background Recombinant human GH(rhGH)was first approved to treat children with growth hormone deficiency(GHD)by Food and Drug Administration(FDA)in the United States in 1985.The indications subsequently expanded to growth failure secondary to chronic renal failure,Turner syndrome,Prader‒Willi syndrome,small for gestational age(SGA)without catch-up growth,idiopathic short stature(ISS),SHOX deficiency,Noonan syndrome and so on[1].The efficacy and the safety of rhGH have been proven in randomized controlled trials(RCTs),which are considered the highest level of evidences in clinical practice.However,due to the strict criteria and short observational time,RCTs could not fully reflect the reality of rhGH,especially in terms of safety[2].
基金supported by the PetroChina Youth Innovation Foundation (No. 06E1018)Key Subject Construction Project of Sichuan Province (No. SZD0414)
文摘The Lower Triassic Feixianguan （飞仙关） Formation oolitic shoal reservoir in the Sichuan （四川） basin （Southwest China） is currently an exploration and research highlight in China. The reservoir is widely believed to be formed mainly by burial dissolution and/or dolomitization on the basis of primary intergranular pores. In this study, through a comprehensive geological study on the whole basin, the dissolution and dolomitization are suggested not to be the fundamental factor of reservoir formation and there thus may be a possible new fundamental mechanism-the preservation of primary intergranular pores, i.e., the retention diagenesis. Based on this, a complex and multi-stage reservoir evolution and formation model is proposed. In the model, the depositional environment is the basis of reservoir initial formation. Subsequently, early compaction and shallow burial cementation result in the primary reservoir differentiation. Then, multi-stage burial dissolution alters and adjusts the reservoir. Because the last stage gaseous hydrocarbons have little diagenetic impact, the reservoir is formed finally. Therefore, this study presents a possible new fundamental mechanism and evolution model for the reservoir formation. The results can be applied in the regional reservoir predication and shaping exploration strategies, and provide reference for the study of shoal reservoirs in other areas.
文摘BACKGROUND： Some research exists on the effect of non-pharmacological approaches for labor pain relief However, there is limited information about effectiveness of breathing exercises in pregnant women to reduce maternal pain during labor. OBJECTIVE： To determine whether breathing exercises for pregnant women during the second stage of labor have beneficial effects on maternal pain, duration of labor, and the first-minute Appearance, Pulse, Grimace, Activity and Respiration （APGAR） scores. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS： This randomized clinical trial involved 250 pregnant women, who were randomly divided into two groups： intervention group （IG; n = 125） and control group （CG; n = 125）. IG received one session breathing exercise training and performed breathing exercises during the second stage of labor versus the CG that did not receive any breathing exercise training. MAIN OUTCOME MEASURES： The effects of breathing exercises on maternal pain were determined by Visual Analogue Scale （VAS）, duration of the second stage of labor, and the first-minute APGAR scores. RESULTS： The mean age of the participants was （23.2 _＋ 4.2） （range： 18 to 42） years. Both IG and CG had similar baseline characteristics in terms of age, education level, occupation, and smoking （P 〉 0.05）. The mean VAS scores of IG and CG were （88.2 ＋_ 6.3） and （90.5 ＋_ 7.0）, respectively （P 〈 0.001）. The duration of the second stage of labor was （369.6 ＋ 92.0） s for IG and （440.7 ＋ 142.5） s for CG （P 〈 0.001 ）. The mean first-minute APGAR scores were （8.84 ＋ 0.50） for IG and （8.73 ＋ 0.89） for CG （P 〉 0.05）. CONCLUSION： Based on this study, breathing exercises with deep inhalation and exhalation in pregnant women are effective in reducing the perception of labor pain and shortening the duration of the second stage of delivery. Therefore, we recommend breathing exercises as an effective modality for labor pain management and shortening the duration of labor. TRIAL REGISTRATION： This study is registered on the website of ClinicalTrials.gov （www.clinicaltrials.gov） with the number of NCT03066973.
文摘目的:观察基于名中医经验的中医辨证组方对老年慢性肾炎(CKD1-3a期)患者的有效性和安全性。方法:将84例老年慢性肾炎患者随机分成治疗组(42例)和对照组(42例)。治疗组采用西医基础联合中医辨证组方治疗;对照组仅接受西医基础治疗,疗程均为24周。观察两组治疗前后24 h尿蛋白定量(24 h UPQ)、肾小球滤过率(eGFR)等临床指标变化,以及疗效和安全性。结果:与本组基线比较,两组治疗后12、18、24周24 h UPQ均显著下降(P<0.01),且24周时治疗组优于对照组(P<0.01)。治疗组总有效率为67.57%,对照组总有效率41.67%,治疗组显著高于对照组(P<0.05)。将慢性肾脏病(CKD)3a期患者进行亚组分析提示,24周后治疗组eGFR较本组基线及同期对照组显著升高(P<0.01,P<0.05),而对照组治疗前后无显著变化。治疗组不良反应发生4例,对照组2例,两组无严重不良反应出现。结论:基于名中医经验的中医辨证组方治疗老年慢性肾炎(CKD1-3a期),可减少尿蛋白,提高临床疗效,对其中的CKD3a期患者可能具有改善eGFR作用,且安全性较好。
