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Research on fiber optic gyro signal de-noising based on wavelet packet soft-threshold 被引量:7
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作者 Qian Huaming & Ma Jichen Coll.of Automation,Harbin Engineering Univ.,Harbin 150001,P.R.China 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2009年第3期607-612,共6页
Gyro's drift is not only the main drift error which influences gyro's precision but also the primary factor that affects gyro's reliability. Reducing zero drift and random drift is a key problem to the output of a ... Gyro's drift is not only the main drift error which influences gyro's precision but also the primary factor that affects gyro's reliability. Reducing zero drift and random drift is a key problem to the output of a gyro signal. A three-layer de-nosing threshold algorithm is proposed based on the wavelet decomposition to dispose the signal which is collected from a running fiber optic gyro (FOG). The coefficients are obtained from the three-layer wavelet packet decomposition. By setting the high frequency part which is greater than wavelet packet threshold as zero, then reconstructing the nodes which have been filtered out noise and interruption, the soft threshold function is constructed by the coefficients of the third nodes. Compared wavelet packet de-noise with forced de-noising method, the proposed method is more effective. Simulation results show that the random drift compensation is enhanced by 13.1%, and reduces zero drift by 0.052 6°/h. 展开更多
关键词 wavelet transform DRIFT fiber optic gyro soft-threshold signal de-noising
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Signal de-noising method based on wavelet decomposition
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作者 冯浩 石晓丹 +1 位作者 黄晓敏 张志杰 《Journal of Measurement Science and Instrumentation》 CAS 2014年第3期33-37,共5页
A noise reduction method for infrared detector output signal is studied during dynamic calibration of thermocou- pie. Firstly, the deficiency of the classical filter method is analyzed and the application of the wavel... A noise reduction method for infrared detector output signal is studied during dynamic calibration of thermocou- pie. Firstly, the deficiency of the classical filter method is analyzed and the application of the wavelet analysis is introduced for signal de-noising during the dynamic testing. Secondly, the theoretical basis of wavelet analysis, the choice of wavelet base and the determination of decomposed series and threshold are analyzed. Finally, the de-noising experiment for infrared detector signal is carried out on the Matlab platform. The results indicate the proposed wavelet de-noising method is effective to remove fixed frequency and high-frequency noise; furthermore, good synchronization is achieved between the de-noised signal and the useful signal components in the original signal, which is of great significance to thermocouple modeling analys- is. 展开更多
关键词 wavelet analysis dynamic calibration THERMOCOUPLE de-noising
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Geotechnical engineering blasting:a new modal aliasing cancellation methodology of vibration signal de-noising 被引量:5
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作者 Yi Wenhua Yan Lei +3 位作者 Wang Zhenhuan Yang Jianhua Tao Tiejun Liu Liansheng 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2022年第2期313-323,共11页
In the present study of peak particle velocity(PPV)and frequency,an improved algorithm(principal empirical mode decomposition,PEMD)based on principal component analysis(PCA)and empirical mode decomposition(EMD)is prop... In the present study of peak particle velocity(PPV)and frequency,an improved algorithm(principal empirical mode decomposition,PEMD)based on principal component analysis(PCA)and empirical mode decomposition(EMD)is proposed,with the goal of addressing poor filtering de-noising effects caused by the occurrences of modal aliasing phenomena in EMD blasting vibration signal decomposition processes.Test results showed that frequency of intrinsic mode function(IMF)components decomposed by PEMD gradually decreases and that the main frequency is unique,which eliminates the phenomenon of modal aliasing.In the simulation experiment,the signal-to-noise(SNR)and root mean square errors(RMSE)ratio of the signal de-noised by PEMD are the largest when compared to EMD and ensemble empirical mode decomposition(EEMD).The main frequency of the de-noising signal through PEMD is 75 Hz,which is closest to the frequency of the noiseless simulation signal.In geotechnical engineering blasting experiments,compared to EMD and EEMD,the signal de-noised by PEMD has the lowest level of distortion,and the frequency band is distributed in a range of 0-64 Hz,which is closest to the frequency band of the blasting vibration signal.In addition,the proportion of noise energy was the lowest,at 1.8%. 展开更多
关键词 blasting vibration frequency empirical mode decomposition modal aliasing de-noising
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Application of RLS adaptive filteringin signal de-noising 被引量:6
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作者 程学珍 徐景东 +1 位作者 卫阿盈 逄明祥 《Journal of Measurement Science and Instrumentation》 CAS 2014年第1期32-36,共5页
In view of the problem that noises are prone to be mixed in the signals,an adaptive signal de-noising system based on reursive least squares (RLS) algorithm is introduced.The principle of adaptive filtering and the ... In view of the problem that noises are prone to be mixed in the signals,an adaptive signal de-noising system based on reursive least squares (RLS) algorithm is introduced.The principle of adaptive filtering and the process flow of RLS algorithm are described.Through example simulation,simulation figures of the adaptive de-noising system are obtained.By analysis and comparison,it can be proved that RLS adaptive filtering is capable of eliminating the noises and obtaining useful signals in a relatively good manner.Therefore,the validity of this method and the rationality of this system are demonstrated. 展开更多
关键词 de-noising adaptive filtering recursive least squares (RLS) algorithm
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Technology of signal de-noising and singularity elimination based on wavelet transform 被引量:1
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作者 赵国建 韩宝玲 +1 位作者 罗庆生 王鑫 《Journal of Beijing Institute of Technology》 EI CAS 2011年第4期509-513,共5页
Based on wavelet transform theory,a method for signal de-noising and singularity detection and elimination is proposed,which can reduce the noises and express local singularity.Each singularity can also be detected an... Based on wavelet transform theory,a method for signal de-noising and singularity detection and elimination is proposed,which can reduce the noises and express local singularity.Each singularity can also be detected and located through the local modulus maxima of wavelet transform.Simulation experiments are conducted with MATLAB software.The experimental results demonstrate that the method proposed in this paper is effective and feasible. 展开更多
关键词 industrial palletizing robot photoelectric sensor wavelet transform wavelet de-noising SINGULARITY
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A Novel Remote Sensing Signal De-noising Algorithm based on Neural Networks and Tensor Analysis
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作者 Wang Wei 《International Journal of Technology Management》 2016年第9期26-28,共3页
. This paper proposes a novel remote sensing signal de-noising algorithm based on neural networks and tensor analysis. The defects exist in a constant deviation between the wavelet coeffi cients and that the wavelet c... . This paper proposes a novel remote sensing signal de-noising algorithm based on neural networks and tensor analysis. The defects exist in a constant deviation between the wavelet coeffi cients and that the wavelet coefficients of the noisy signal to estimate the discontinuity of hard threshold function and soft threshold function, limiting its further application in order to overcome this shortcoming, this paper proposes a new threshold function, compared with the original threshold function, a new threshold function is simple and easy to calculate, not only with the soft threshold function is continuous. To deal with this drawback, we integrate the NN to enhance the model. Neural network belongs to the basic unsupervised learning of neural networks, the principle of competition based on the mechanism of learning and biological and the memory capacity can be increased as the number of learning patterns increases, not only offi ine learning can also be carried out on-line "learning while learning" type. The integrated algorithm can host better performance. 展开更多
关键词 Remote Sensing de-noising ALGORITHM Neural Networks Tensor Analysis
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Application of Wavelet Analysis in Signal De-noising of Blast Shock Wave Overpressure
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作者 蒋建伟 房玉军 +1 位作者 万丽珍 门建兵 《Journal of Measurement Science and Instrumentation》 CAS 2010年第2期145-147,共3页
It' s a problem to be solved how to de-noise the signal of blast shock wave overpressure. In the conventional methods, the high frequency of the signal is cut directly by some mathematics algorithms, such as Fourier ... It' s a problem to be solved how to de-noise the signal of blast shock wave overpressure. In the conventional methods, the high frequency of the signal is cut directly by some mathematics algorithms, such as Fourier Transform, but some of the useful signal will be cut together. We adopt a new method for the signal de-noising of shock wave overpressure by wavelet analysis, There are four steps in this method. Firstly, the original signal is de-compoed. Then the time-frequency features of the signal and noise are analyzed. Thirdly, the noise is separated from the signal by only cutting its frequency while the useful signal frequency is reserved as much as possible. Lastly, the useful signal with least loss of information is recovered by reconstruction process. To verify this method, a blast shock wave signal is de-noised with FFF to make a comparison. The results show that the signal de-noised by wavelet analysis approximates the ideal signal well. 展开更多
关键词 Mast shock wave signal noise wavelet analysis
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Improved signal de-noising in underwater acoustic noise using S-transform: A performance evaluation and comparison with the wavelet transform 被引量:1
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作者 Yasin Yousif Al-Aboosi Ahmad Zuri Sha’ameri 《Journal of Ocean Engineering and Science》 SCIE 2017年第3期172-185,共14页
Sound waves propagate well underwater making it useful for target locating and communication.Underwater acoustic noise(UWAN)affects the reliability in applications where the noise comes from multiple sources.In this p... Sound waves propagate well underwater making it useful for target locating and communication.Underwater acoustic noise(UWAN)affects the reliability in applications where the noise comes from multiple sources.In this paper,a novel signal de-noising technique is proposed using S-transform.From the time-frequency representation,de-noising is performed using soft thresholding with universal threshold estimation which is then reconstructed.The UWAN used for the validation is sea truth data collected at Desaru beach on the eastern shore of Johor in Malaysia with the use of broadband hydrophones.The comparison is made with the more conventionally used wavelet transform de-noising method.Two types of signals are evaluated:fixed frequency signals and time-varying signals.The results demonstrate that the proposed method shows better signal to noise ratio(SNR)by 4 dB and lower root mean square error(RMSE)by 3 dB achieved at the Nyquist sampling frequency compared to the previously proposed de-noising method like wavelet transform. 展开更多
关键词 Underwater acoustic noise Time-frequency analysis Wavelet transforms S-transforms signal de-noising
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Moving horizon based wavelet de-noising method of dual-observed geomagnetic signal for nonlinear high spin projectile roll positioning 被引量:3
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作者 Ting-ting Yin Fang-xiu Jia Xiao-ming Wang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2020年第2期417-424,共8页
Phase-frequency characte ristics of approximate sinusoidal geomagnetic signals can be used fo r projectile roll positioning and other high-precision trajectory correction applications.The sinusoidal geomagnetic signal... Phase-frequency characte ristics of approximate sinusoidal geomagnetic signals can be used fo r projectile roll positioning and other high-precision trajectory correction applications.The sinusoidal geomagnetic signal deforms in the exposed and magnetically contaminated environment.In order to preciously recognize the roll information and effectively separate the noise component from the original geomagnetic sequence,based on the error source analysis,we propose a moving horizon based wavelet de-noising method for the dual-observed geomagnetic signal filtering where the captured rough roll frequency value provides reasonable wavelet decomposition and reconstruction level selection basis for sampled sequence;a moving horizon window guarantees real-time performance and non-cumulative calculation amount.The complete geomagnetic data in full ballistic range and three intercepted paragraphs are used for performance assessment.The positioning performance of the moving horizon wavelet de-noising method is compared with the band-pass filter.The results show that both noise reduction techniques improve the positioning accuracy while the wavelet de-noising method is always better than the band-pass filter.These results suggest that the proposed moving horizon based wavelet de-noising method of the dual-observed geomagnetic signal is more applicable for various launch conditions with better positioning performance. 展开更多
关键词 High-spin PROJECTILE ROLL POSITIONING Dual-observed GEOMAGNETIC signal WAVELET de-noising Discrete WAVELET transform
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Fault Diagnosis of Motor in Frequency Domain Signal by Stacked De-noising Auto-encoder 被引量:5
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作者 Xiaoping Zhao Jiaxin Wu +2 位作者 Yonghong Zhang Yunqing Shi Lihua Wang 《Computers, Materials & Continua》 SCIE EI 2018年第11期223-242,共20页
With the rapid development of mechanical equipment,mechanical health monitoring field has entered the era of big data.Deep learning has made a great achievement in the processing of large data of image and speech due ... With the rapid development of mechanical equipment,mechanical health monitoring field has entered the era of big data.Deep learning has made a great achievement in the processing of large data of image and speech due to the powerful modeling capabilities,this also brings influence to the mechanical fault diagnosis field.Therefore,according to the characteristics of motor vibration signals(nonstationary and difficult to deal with)and mechanical‘big data’,combined with deep learning,a motor fault diagnosis method based on stacked de-noising auto-encoder is proposed.The frequency domain signals obtained by the Fourier transform are used as input to the network.This method can extract features adaptively and unsupervised,and get rid of the dependence of traditional machine learning methods on human extraction features.A supervised fine tuning of the model is then carried out by backpropagation.The Asynchronous motor in Drivetrain Dynamics Simulator system was taken as the research object,the effectiveness of the proposed method was verified by a large number of data,and research on visualization of network output,the results shown that the SDAE method is more efficient and more intelligent. 展开更多
关键词 Big data deep learning stacked de-noising auto-encoder fourier transform
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Automatic de-noising and recognition algorithm for drilling fluid pulse signal 被引量:1
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作者 HU Yongjian HUANG Yanfu LI Xianyi 《Petroleum Exploration and Development》 2019年第2期393-400,共8页
Wavelet forced de-noising algorithm is suitable for denoising of unsteady drilling fluid pulse signal, including baseline drift rectification and two-stage de-noising processing of frame synchronization signal and ins... Wavelet forced de-noising algorithm is suitable for denoising of unsteady drilling fluid pulse signal, including baseline drift rectification and two-stage de-noising processing of frame synchronization signal and instruction signal. Two-stage de-noising processing can reduce the impact of baseline drift and determine automatic peak detection threshold range for signal recognition by distinguishing different features of frame synchronization pulse and instruction pulse. Rising and falling edge relative protruding threshold is defined for peak detection in signal recognition, which can make full use of the degree of the signal peak change and detect peaks flexibly with rising and falling edge relative protruding threshold combination. A synchronous decoding method was designed to reduce position uncertainty of the frame synchronization pulse and eliminate the accumulative error of time base drift, which determines the first instruction pulse position according to position of the frame synchronization pulse and decodes subsequent instruction pulse by taking current instruction pulse as new bit synchronization pulse. Special tool software was developed to tune algorithm parameters, which has a decoding success rate of about 95% for the universal coded signals. For the special coded signals with check byte, decoding success rate using the automatic threshold adjustment algorithm is as high as 99%. 展开更多
关键词 drilling fluid pulse signal signal processing DECODING SUCCESS rate AUTOMATIC de-noising and recognition wavelet FORCED de-noising peak detection synchronous DECODING
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Lidar signal de-noising based on wavelet trimmed thresholding technique 被引量:3
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作者 方海涛 黄德双 《Chinese Optics Letters》 SCIE EI CAS CSCD 2004年第1期1-3,共3页
Lidar is an efficient tool for remote monitoring, but the effective range is often limited by signal-to-noise ratio (SNR). By the power spectral estimation, we find that digital filters are not fit for processing lida... Lidar is an efficient tool for remote monitoring, but the effective range is often limited by signal-to-noise ratio (SNR). By the power spectral estimation, we find that digital filters are not fit for processing lidar signals buried in noise. In this paper, we present a new method of the lidar signal acquisition based on the wavelet trimmed thresholding technique to increase the effective range of lidar measurements. The performance of our method is investigated by detecting the real signals in noise. The experiment results show that our approach is superior to the traditional methods such as Butterworth filter. 展开更多
关键词 Noise abatement signal to noise ratio Wavelet transforms
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Implementation of GPR Signals De-Noising Based on DSP
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作者 CHEN Xiao-li TIAN Mao ZHOU Hui-lin 《Wuhan University Journal of Natural Sciences》 EI CAS 2005年第6期1005-1008,共4页
An important issue of ground-penetrating radar (GPR) signals analysis is de-noising thai is the guarantee of acquiring good detecting effect. The paper illustrates a successful application of digital single process... An important issue of ground-penetrating radar (GPR) signals analysis is de-noising thai is the guarantee of acquiring good detecting effect. The paper illustrates a successful application of digital single processor (DSP) based on wavelet shrinkage algorithm. In order to realize real-time GPP, signals analysis, some key issues are discussed such as the realization of fast wavelet transformation, the selection of CPU chip and the optimization of data movement. Experimenial results show that the DSP based application not only basically meets the real-time requirement of GPP, signals analysis, but also assures the quality of the GPR signals analysis. 展开更多
关键词 wavelet shrinkage de-noising GPR digital signal processor real time soft thresholding SNR
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Modeling and Comprehensive Review of Signaling Storms in 3GPP-Based Mobile Broadband Networks:Causes,Solutions,and Countermeasures
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作者 Muhammad Qasim Khan Fazal Malik +1 位作者 Fahad Alturise Noor Rahman 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期123-153,共31页
Control signaling is mandatory for the operation and management of all types of communication networks,including the Third Generation Partnership Project(3GPP)mobile broadband networks.However,they consume important a... Control signaling is mandatory for the operation and management of all types of communication networks,including the Third Generation Partnership Project(3GPP)mobile broadband networks.However,they consume important and scarce network resources such as bandwidth and processing power.There have been several reports of these control signaling turning into signaling storms halting network operations and causing the respective Telecom companies big financial losses.This paper draws its motivation from such real network disaster incidents attributed to signaling storms.In this paper,we present a thorough survey of the causes,of the signaling storm problems in 3GPP-based mobile broadband networks and discuss in detail their possible solutions and countermeasures.We provide relevant analytical models to help quantify the effect of the potential causes and benefits of their corresponding solutions.Another important contribution of this paper is the comparison of the possible causes and solutions/countermeasures,concerning their effect on several important network aspects such as architecture,additional signaling,fidelity,etc.,in the form of a table.This paper presents an update and an extension of our earlier conference publication.To our knowledge,no similar survey study exists on the subject. 展开更多
关键词 signaling storm problems control signaling load analytical modeling 3GPP networks smart devices diameter signaling mobile broadband data access data traffic mobility management signaling network architecture 5G mobile communication
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A New Matlab De-noising Algorithm for Signal Extraction 被引量:1
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作者 ZHANG Fu-ming WU Song-lin 《International Journal of Plant Engineering and Management》 2007年第1期18-23,共6页
The goal of a de-noising algorithm is to reconstruct a signal from its noise-corrupted observations. Perfect reconstruction is seldom possible and performance is measured under a given fidelity criterion. In a recent ... The goal of a de-noising algorithm is to reconstruct a signal from its noise-corrupted observations. Perfect reconstruction is seldom possible and performance is measured under a given fidelity criterion. In a recent work, the authors addressed a new Matlab algorithm for de-noising. A key method of the algorithm is selecting an optimal basis from a library of wavelet bases for ideal de-noising. The algorithm with an optimal basis from a library of wavelet bases for de-noising was created through making use of Matlab's Wavelet Toolbox. The experimental results show that the new algorithm is efficient in signal de-nosing. 展开更多
关键词 WAVELET de-noising MATLAB
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A De-Noising Method for Track State Detection Signal Based on EMD
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作者 Liming Li Xiaodong Chai +1 位作者 Shubin Zheng Wenfa Zhu 《Journal of Signal and Information Processing》 2014年第4期104-111,共8页
In the track irregularity detection, the acceleration signals of the inertial measurement unit (IMU) output which with low frequency components and noise, this paper studied a de-noising algorithm. Based on the criter... In the track irregularity detection, the acceleration signals of the inertial measurement unit (IMU) output which with low frequency components and noise, this paper studied a de-noising algorithm. Based on the criterion of consecutive mean square error, a de-noising method for IMU acceleration signals based on empirical mode decomposition (EMD) was proposed. This method can divide the intrinsic mode functions (IMFs) derived from EMD into signal dominant modes and noise dominant modes, then the modes reflecting the important structures of a signal were combined together to form partially reconstructed de-noised signal. Simulations were conducted for simulated signals and a real IMU acceleration signals using this method. Experimental results indicate that this method can efficiently and adaptively remove noise, and this method can better meet the precision requirement. 展开更多
关键词 TRACK IRREGULARITY signal de-noising Empirical Mode Decomposition Consecutive Mean SQUARE Error
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A De-Noising Method for Track State Detection Signal Based on the Statistical Characteristic of Noise
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作者 Liming Li Xiaodong Chai +1 位作者 Shubin Zheng Wenfa Zhu 《Journal of Transportation Technologies》 2014年第4期327-336,共10页
Based on the statistical characteristics analysis of random noise power and autocorrelation function, this paper proposes a de-noising method for track state detection signal by using Empirical Mode Decomposition (EMD... Based on the statistical characteristics analysis of random noise power and autocorrelation function, this paper proposes a de-noising method for track state detection signal by using Empirical Mode Decomposition (EMD). This method is used to noise reduction refactoring for the first Intrinsic Mode Function (IMF) component in accordance with the “random sort-accumulation-average-refactoring' order. Signal autocorrelation function characteristics are used to determine the cut-off point of the dominant mode. This method was applied to test signals and the actual inertial unit signals;the experimental results show that the method can effectively remove the noise and better meet the precision requirement. 展开更多
关键词 TRACK Inspection LONG Wave IRREGULARITY Empirical Mode DECOMPOSITION de-noising
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Molecular mechanism of pancreatic ductal adenocarcinoma:The heterogeneity of cancer-associated fibroblasts and key signaling pathways
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作者 Zhong-Yuan Hu Ding Ding +3 位作者 Yu Song Ya-Feng Deng Cheng-Ming Zhang Tao Yu 《World Journal of Clinical Oncology》 2025年第2期18-28,共11页
Pancreatic ductal adenocarcinoma stands out as an exceptionally fatal cancer owing to the complexities associated with its treatment and diagnosis,leading to a notably low five-year survival rate.This study offers a d... Pancreatic ductal adenocarcinoma stands out as an exceptionally fatal cancer owing to the complexities associated with its treatment and diagnosis,leading to a notably low five-year survival rate.This study offers a detailed exploration of epidemiological trends in pancreatic cancer and key molecular drivers,such as mutations in CDKN2A,KRAS,SMAD4,and TP53,along with the influence of cancer-associated fibroblasts(CAFs)on disease progression.In particular,we focused on the pivotal roles of signaling pathways such as the transforming growth factor-βand Wnt/β-catenin pathways in the development of pancreatic cancer and investigated their application in emerging therapeutic strategies.This study provides new scientific perspectives on pancreatic cancer treatment,especially in the development of precision medicine and targeted therapeutic strategies,and demonstrates the importance of signaling pathway research in the development of effective therapeutic regimens.Future studies should explore the subtypes of CAFs and their specific roles in the tumor microenvironment to devise more effective therapeutic methods. 展开更多
关键词 Pancreatic cancer FIBROBLASTS signaling pathways Tumor microenvironment
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Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats
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作者 Ping Zhang Ying Zhu +7 位作者 Pu Chen Tong Zhou Zhe-Yi Han Jun Xiao Jian-Feng Ma Wen Ma Peng Zang Ying Chen 《World Journal of Gastroenterology》 SCIE CAS 2025年第1期93-109,共17页
BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling p... BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal cells.Moreover,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal cells.Cajal cells are the pacemakers of gastrointestinal motility.AIM To investigate the effects of Bifidobacterium lactis(B.lactis)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit pathway.METHODS The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 days.The tail group was given B.lactis BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/day.Hematoxylin&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and PCR.The fecal flora and mucosal flora of rats in each group were detected by 16S rRNA.RESULTS Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic intervention.Simulated microgravity reduced the expressions of SCF and c-kit,and increased the expressions of ERK and P-ERK in the gastric antrum of rats.However,after probiotic intervention,the expressions of SCF and ckit were increased,while the expressions of ERK and P-ERK were decreased,with statistical significance(P<0.05).In addition,simulated microgravity can reduce the operational taxonomic unit(OTU)of the overall intestinal flora of rats,B.lactis BLa80 can increase the OTU of rats,simulated microgravity can reduce the overall richness and diversity of stool flora of rats,increase the abundance of firmicutes in stool flora of rats,and reduce the abundance of Bacteroides in stool flora of rats,most of which are mainly beneficial bacteria.Simulated microgravity can increase the overall richness and diversity of mucosal flora,increase the abundance of Bacteroides and Desulphurides in the rat mucosal flora,and decrease the abundance of firmicutes,most of which are proteobacteria.After probiotics intervention,the overall Bacteroidetes trend in simulated microgravity rats was increased.CONCLUSION B.lactis BLa80 can ameliorate intestinal mucosal injury,regulate intestinal flora,inhibit ERK expression,and activate the SCF/c-kit signaling pathway,which may have a facilitating effect on gastrointestinal motility in simulated microgravity rats. 展开更多
关键词 Simulated microgravity RAT Intestinal flora Gastrointestinal motility Stem cell factor/c-kit signaling pathway
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Traditional Chinese medicine in the treatment of Helicobacter pylorirelated gastritis:The mechanisms of signalling pathway regulations
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作者 Pei-Pei Zhang Liang Li +3 位作者 Hao-Yu Qu Guang-Yu Chen Meng-Zhou Xie Yan-Kun Chen 《World Journal of Gastroenterology》 SCIE CAS 2025年第3期11-28,共18页
Helicobacter pylori-associated gastritis(HPAG)is a common condition of the gastrointestinal tract.However,extensive and long-term antibiotic use has resulted in numerous adverse effects,including increased resistance,... Helicobacter pylori-associated gastritis(HPAG)is a common condition of the gastrointestinal tract.However,extensive and long-term antibiotic use has resulted in numerous adverse effects,including increased resistance,gastrointestinal dysfunction,and increased recurrence rates.When these concerns develop,traditional Chinese medicine(TCM)may have advantages.TCM is based on the concept of completeness and aims to eliminate pathogens and strengthen the body.It has the potential to prevent this condition while also boosting the rate of Helicobacter pylori eradication.This review elaborates on the mechanism of TCM treatment for HPAG based on cellular signalling pathways,which reflects the flexibility of TCM in treating diseases and the advantages of multi-level,multipathway,and multi-target treatments for HPAG. 展开更多
关键词 Helicobacter pylori Helicobacter pylori-associated gastritis Traditional Chinese medicine signalling pathway Eliminate pathogens Strengthen the body
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