Objective:This study mainly explores the clinical effect of Shashen Maidong Decoction in the treatment of advanced lung cancer.Methods:Twelve patients with advanced lung cancer from Inner Mongolia Baicaotang Qin's...Objective:This study mainly explores the clinical effect of Shashen Maidong Decoction in the treatment of advanced lung cancer.Methods:Twelve patients with advanced lung cancer from Inner Mongolia Baicaotang Qin's Zhong Meng Medical Hospital were randomly selected from February 2016 to February 2021.They were divided into two groups:the reference group and study group by the digital table method.The reference group was treated with conventional chemotherapy while the study group was treated with Shashen Maidong Decoction plus conventional chemotherapy.Results:The remission rate of the study group was higher than that of the reference group,and the incidence of adverse reactions was lower than that of the reference group,P<0.05.The levels of CD3^(+),CD4^(+),and CD4^(+)/CD8^(+)in the study group were higher than those in the reference group(P<0.05).After treatment,the quality of life score of the study group was higher than that of the reference group(P<0.05).Conclusion:Shashen Maidong Decoction can effectively reduce adverse reactions and improve the condition of patients in the treatment of advanced lung cancer.展开更多
Objective: To evaluate the effect of Shashen Maidong Decoction (SSMDD) on gastric motility.Method: Effect of SSMDD on the gastric motility of mice and rats was observed in vivo by administration of SSMDD in various do...Objective: To evaluate the effect of Shashen Maidong Decoction (SSMDD) on gastric motility.Method: Effect of SSMDD on the gastric motility of mice and rats was observed in vivo by administration of SSMDD in various dosages and observation on gastric phenol red excretion rate, gastric emptying rate, frequency and amplitude of contraction of fundic longitudinal muscles, etc. Results: SSMDD could reduce markedly the gastric phenol red excretion rate of mice, antagonize the acceleration of gastric emptying induced by neostigmine, inhibit the frequency and amplitude of contraction of fundic longitudinal muscle, slow down the frequency and decrease the amplitude of gastric peristalsis, and reduce the gastric hypermotility induced by indomethacin significantly. Conclusion: SSMDD has evident inhibition action on motility of experimental animals in vivo, its mechanism might be related with adrenergic nerve and metabolism of prostaglandin E.展开更多
文摘Objective:This study mainly explores the clinical effect of Shashen Maidong Decoction in the treatment of advanced lung cancer.Methods:Twelve patients with advanced lung cancer from Inner Mongolia Baicaotang Qin's Zhong Meng Medical Hospital were randomly selected from February 2016 to February 2021.They were divided into two groups:the reference group and study group by the digital table method.The reference group was treated with conventional chemotherapy while the study group was treated with Shashen Maidong Decoction plus conventional chemotherapy.Results:The remission rate of the study group was higher than that of the reference group,and the incidence of adverse reactions was lower than that of the reference group,P<0.05.The levels of CD3^(+),CD4^(+),and CD4^(+)/CD8^(+)in the study group were higher than those in the reference group(P<0.05).After treatment,the quality of life score of the study group was higher than that of the reference group(P<0.05).Conclusion:Shashen Maidong Decoction can effectively reduce adverse reactions and improve the condition of patients in the treatment of advanced lung cancer.
文摘Objective: To evaluate the effect of Shashen Maidong Decoction (SSMDD) on gastric motility.Method: Effect of SSMDD on the gastric motility of mice and rats was observed in vivo by administration of SSMDD in various dosages and observation on gastric phenol red excretion rate, gastric emptying rate, frequency and amplitude of contraction of fundic longitudinal muscles, etc. Results: SSMDD could reduce markedly the gastric phenol red excretion rate of mice, antagonize the acceleration of gastric emptying induced by neostigmine, inhibit the frequency and amplitude of contraction of fundic longitudinal muscle, slow down the frequency and decrease the amplitude of gastric peristalsis, and reduce the gastric hypermotility induced by indomethacin significantly. Conclusion: SSMDD has evident inhibition action on motility of experimental animals in vivo, its mechanism might be related with adrenergic nerve and metabolism of prostaglandin E.