A new baccharane-type triterpene, 3-acetoxy-9(11)-baccharene(1),as well as a known compound, a-amyrin(2), has been isolated from the ether extract of the roots of Saussurea lappa C. B. Clarke. The structure of the new...A new baccharane-type triterpene, 3-acetoxy-9(11)-baccharene(1),as well as a known compound, a-amyrin(2), has been isolated from the ether extract of the roots of Saussurea lappa C. B. Clarke. The structure of the new compound was identified by spectrum analysis.展开更多
Two new baccharane-type glycosides（1 and 2）, together with seven known baccharane-type glycosides （3u9） hosenkoside A, hosenkoside B, hosenkoside C, hosenkoside F, hosenkoside M, hosenkoside K and hosenko- side G ...Two new baccharane-type glycosides（1 and 2）, together with seven known baccharane-type glycosides （3u9） hosenkoside A, hosenkoside B, hosenkoside C, hosenkoside F, hosenkoside M, hosenkoside K and hosenko- side G were isolated from the dried seeds of Impatientis balsamina L. The new baccharane-type glycosides were identified as honsenkol A-3-O-β-D-glucopyranosyl-26-O-p-D-glucopyranosyl-28-O-β-D-glucopyranosyl-O-β-D- glucopyranosyl（1） and （3S,4R,17R,20S）17-hydrroxy-3-O-β-D-xylopyranose（12）-β-D-glucopyranosyl-26-O-β-D- glucopyranosyl-28-O-β-D-glucopyranosyl-21,24-epoxybaccharane（2）, respectively, by spectroscopic methods, in- cluding NMR（1D and 2D）, IR and HR-ESI-MS. Compounds 1 and 2 were evaluated for in vitro inhibitory activity against the cell lines. Compound 2 with a new baccharane skeleton had anti-hepatic fibrosis activity against A375 cells in bioassay results, which means the new compounds have potential value in antitumor applications.展开更多
基金This work was supported by the Kunming Institute of Botany,Chinese Academy of Sciences.
文摘A new baccharane-type triterpene, 3-acetoxy-9(11)-baccharene(1),as well as a known compound, a-amyrin(2), has been isolated from the ether extract of the roots of Saussurea lappa C. B. Clarke. The structure of the new compound was identified by spectrum analysis.
基金Supported by the National Natural Science Foundation of China（No. 81173602）.
文摘Two new baccharane-type glycosides（1 and 2）, together with seven known baccharane-type glycosides （3u9） hosenkoside A, hosenkoside B, hosenkoside C, hosenkoside F, hosenkoside M, hosenkoside K and hosenko- side G were isolated from the dried seeds of Impatientis balsamina L. The new baccharane-type glycosides were identified as honsenkol A-3-O-β-D-glucopyranosyl-26-O-p-D-glucopyranosyl-28-O-β-D-glucopyranosyl-O-β-D- glucopyranosyl（1） and （3S,4R,17R,20S）17-hydrroxy-3-O-β-D-xylopyranose（12）-β-D-glucopyranosyl-26-O-β-D- glucopyranosyl-28-O-β-D-glucopyranosyl-21,24-epoxybaccharane（2）, respectively, by spectroscopic methods, in- cluding NMR（1D and 2D）, IR and HR-ESI-MS. Compounds 1 and 2 were evaluated for in vitro inhibitory activity against the cell lines. Compound 2 with a new baccharane skeleton had anti-hepatic fibrosis activity against A375 cells in bioassay results, which means the new compounds have potential value in antitumor applications.
