As an application instructional course for Aquatic Animal Medicine(AAM),Aquatic Animal Pathogen Biology needs to be guided by a large number of examples and cases,but the current case database construction faces many ...As an application instructional course for Aquatic Animal Medicine(AAM),Aquatic Animal Pathogen Biology needs to be guided by a large number of examples and cases,but the current case database construction faces many urgent problems.In view of this,this paper analyzes the characteristics of professional education of AAM postgraduate students.With the goal of cultivating applied personnel that meet the requirements of the times,and the guiding ideology of strengthening the reform of the education model in colleges and universities,and improving the quantity and quality of personnel training,it builds a case database for the course Aquatic Animal Pathogen Biology in accordance with modern postgraduate teaching needs.展开更多
This paper intends to combine the development trend of the subject,restructure and optimize the course content,and construct the service learning model of Pathogenic Biology of Aquatic Animals for postgraduates.At the...This paper intends to combine the development trend of the subject,restructure and optimize the course content,and construct the service learning model of Pathogenic Biology of Aquatic Animals for postgraduates.At the same time,through service practice,it is needed to further consolidate curriculum knowledge and skills,stimulate the learning initiative and enthusiasm of postgraduates,expand professional knowledge,improve professional quality,and lay a solid foundation for serving the national rural revitalization strategy in the future.展开更多
Objective:To investigate the prevalence,isolation,identification,characterization,antibiotic profile and pathogenicity of Legionellae isolated from various set of waters.Methods:A total of 400 water samples were colle...Objective:To investigate the prevalence,isolation,identification,characterization,antibiotic profile and pathogenicity of Legionellae isolated from various set of waters.Methods:A total of 400 water samples were collected from different water sources.Water samples were pretreated using acid treatment followed by concentration and culture on buffered charcoal yeast extract agar.Parameters like ability of Legionella isolates to grow in various p H range,effect of different concentrations of chlorine and effect of different temperature optima were set up.Biochemical tests were performed to separate Legionellae into species.Antibiotic sensitivity tests and test for pathogenicity were also conducted on isolated strains.Results:The rates of isolation of Legionella pneumophila(L.pneumophila) in different water sources were found to be 20%(lakes),10%(ponds),8%(water-tanks) and 1%(rivers).Most of the isolates could grow in variable p H 6–8 and it could also survive the normal level of chlorination and even at temperature of 42 C.Isolated species of Legionellae resulted in identification of 5 different species,L.pneumophila being the dominant one.Strains of L.pneumophila were resistant to many antibiotics.Inoculation of Legionellae into intracerebral route of suckling mice revealed that L.pneumophila was the most virulent.Conclusions:Serious and fatal L.pneumophila infections may be transmitted through water.Legionella can survive under various conditions in various water sources.L.pneumophila is the important pathogen causing human disease.Great challenge prevails to health care professionals because these Legionellae acquired antibiotic resistance to many routinely prescribed antibiotics.展开更多
Arenaviruses belong to the family of RNA viruses that can infect humans in various ways and cause different degrees of mortality.Rodents is the mainly hosts.Human pathogenic arenaviruses include lymphocytic choroid me...Arenaviruses belong to the family of RNA viruses that can infect humans in various ways and cause different degrees of mortality.Rodents is the mainly hosts.Human pathogenic arenaviruses include lymphocytic choroid meningitis,Lassa virus group and Takarib virus group,which cause human lymphocytic choriomeningitis and human hemorrhagic diseases.Rodents account for about 43%of mammalian species.At present,more than 30 highly pathogenic viruses have been found in rodents,including arenaviruses.The arenaviridae that infects rodents are mainly mammalian arenaviruses.This article reviews the etiology,clinicopathology,epidemiology,prevention and control of arenavirus,and provides references for the research and prevention of arenavirus.展开更多
Thailand has continuously established biosafety and security laws since 1932.The present law,the Pathogens and Animal Toxins Act 2015,was established for the controlled production,possession,sales,import,export,and tr...Thailand has continuously established biosafety and security laws since 1932.The present law,the Pathogens and Animal Toxins Act 2015,was established for the controlled production,possession,sales,import,export,and transit of pathogens and animal toxins.The law is in accordance with the current world situation—that is,outbreaks of emerging and re-emerging diseases and the development of modern biotechnology,such as genetic modification of pathogens with the potential for beneficial or harmful use.The principles of the pathogen control measures of Thai law are similar to those of foreign laws in countries such as Canada,the United States,Singapore,and the People’s Republic of China.Control measures are based on the risk levels of pathogens to humans,animals,and the environment.This review briefly presents details of the law’s development in Thailand.Details are given in comparison with those of other countries;the export and import of pathogens and animal toxins according to EU export controls are also discussed.The practice and experience of applying the law in Thailand are also presented.Dissemination of enforcement details will ensure effective legal biosafety and biosecurity control measures in Thailand.This may be useful for establishing a law involving regulatory controls for biosafety and biosecurity.展开更多
基金Supported by Project of Degree and Postgraduate Education and Teaching Reform of Guangdong Ocean University(202020&202120)Project on Education and Teaching Reform of Higher Education Institutions in Guangdong Province+1 种基金Applied Personnel Training Course of Guangdong Ocean UniversityIndustry-University-Research Institute Cooperation Collaborative Education Teaching Content and Curriculum System Reform Project of Ministry of Education(202101134003).
文摘As an application instructional course for Aquatic Animal Medicine(AAM),Aquatic Animal Pathogen Biology needs to be guided by a large number of examples and cases,but the current case database construction faces many urgent problems.In view of this,this paper analyzes the characteristics of professional education of AAM postgraduate students.With the goal of cultivating applied personnel that meet the requirements of the times,and the guiding ideology of strengthening the reform of the education model in colleges and universities,and improving the quantity and quality of personnel training,it builds a case database for the course Aquatic Animal Pathogen Biology in accordance with modern postgraduate teaching needs.
基金Supported by the Research Project of Degree and Postgraduate Education Reform of Guangdong Ocean University(202120)Innovation Program of Postgraduate Education in Guangdong Province(Ejiaoyanhan[2022]No.1)。
文摘This paper intends to combine the development trend of the subject,restructure and optimize the course content,and construct the service learning model of Pathogenic Biology of Aquatic Animals for postgraduates.At the same time,through service practice,it is needed to further consolidate curriculum knowledge and skills,stimulate the learning initiative and enthusiasm of postgraduates,expand professional knowledge,improve professional quality,and lay a solid foundation for serving the national rural revitalization strategy in the future.
基金Supported by Rockefeller Foundation,USA(Grant No.External-R.F-2396725281-2015-16)
文摘Objective:To investigate the prevalence,isolation,identification,characterization,antibiotic profile and pathogenicity of Legionellae isolated from various set of waters.Methods:A total of 400 water samples were collected from different water sources.Water samples were pretreated using acid treatment followed by concentration and culture on buffered charcoal yeast extract agar.Parameters like ability of Legionella isolates to grow in various p H range,effect of different concentrations of chlorine and effect of different temperature optima were set up.Biochemical tests were performed to separate Legionellae into species.Antibiotic sensitivity tests and test for pathogenicity were also conducted on isolated strains.Results:The rates of isolation of Legionella pneumophila(L.pneumophila) in different water sources were found to be 20%(lakes),10%(ponds),8%(water-tanks) and 1%(rivers).Most of the isolates could grow in variable p H 6–8 and it could also survive the normal level of chlorination and even at temperature of 42 C.Isolated species of Legionellae resulted in identification of 5 different species,L.pneumophila being the dominant one.Strains of L.pneumophila were resistant to many antibiotics.Inoculation of Legionellae into intracerebral route of suckling mice revealed that L.pneumophila was the most virulent.Conclusions:Serious and fatal L.pneumophila infections may be transmitted through water.Legionella can survive under various conditions in various water sources.L.pneumophila is the important pathogen causing human disease.Great challenge prevails to health care professionals because these Legionellae acquired antibiotic resistance to many routinely prescribed antibiotics.
基金Hainan Provincial Higher Education Science Research Project(Hnky 2020‑33)Key Research and Development Plan of Hainan Province(ZDYF2020150)+4 种基金Major Science and Technology Project of Hainan Province(ZDKJ202003)National Natural Science Foundation of China(32060015)High level Talent Program of Hainan Natural Science Foundation(2019RC218)Hainan Academician Innovation Platform Project(YSPTZX202004)Hainan Academician Workstation Project(SRC200003)。
文摘Arenaviruses belong to the family of RNA viruses that can infect humans in various ways and cause different degrees of mortality.Rodents is the mainly hosts.Human pathogenic arenaviruses include lymphocytic choroid meningitis,Lassa virus group and Takarib virus group,which cause human lymphocytic choriomeningitis and human hemorrhagic diseases.Rodents account for about 43%of mammalian species.At present,more than 30 highly pathogenic viruses have been found in rodents,including arenaviruses.The arenaviridae that infects rodents are mainly mammalian arenaviruses.This article reviews the etiology,clinicopathology,epidemiology,prevention and control of arenavirus,and provides references for the research and prevention of arenavirus.
文摘Thailand has continuously established biosafety and security laws since 1932.The present law,the Pathogens and Animal Toxins Act 2015,was established for the controlled production,possession,sales,import,export,and transit of pathogens and animal toxins.The law is in accordance with the current world situation—that is,outbreaks of emerging and re-emerging diseases and the development of modern biotechnology,such as genetic modification of pathogens with the potential for beneficial or harmful use.The principles of the pathogen control measures of Thai law are similar to those of foreign laws in countries such as Canada,the United States,Singapore,and the People’s Republic of China.Control measures are based on the risk levels of pathogens to humans,animals,and the environment.This review briefly presents details of the law’s development in Thailand.Details are given in comparison with those of other countries;the export and import of pathogens and animal toxins according to EU export controls are also discussed.The practice and experience of applying the law in Thailand are also presented.Dissemination of enforcement details will ensure effective legal biosafety and biosecurity control measures in Thailand.This may be useful for establishing a law involving regulatory controls for biosafety and biosecurity.