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The Middle East and North Africa (MENA) Oil Exporters After the Global Crisis
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作者 Naci Yllmaz Bora Selcuk 《Chinese Business Review》 2012年第7期627-638,共12页
Our research topic is about the economic situation in the Middle East and North Africa (MENA) oil exporters after the global crisis in 2008. The authors tried to find the answers to the questions such as "How bad o... Our research topic is about the economic situation in the Middle East and North Africa (MENA) oil exporters after the global crisis in 2008. The authors tried to find the answers to the questions such as "How bad or good is the situation there?" and "what is the expectation about the future of the region?" Like other countries around the world, the MENA oil exporters, comprised of Algeria, Bahrain, Iran, Iraq, Kuwait, Libya, Oman, Qatar, Saudi Arabia, Sudan, United Arab Emirates, Yemen were adversely affected by the global crisis. The MENA oil exporters are recently recovering from their recession in 2009 when the global crisis was felt intensively there. GDP in the region has grown by 3.5 percent in 2010 after a low growth of 0.7 percent in 2009. The average real GDP growth excluding Libya is projected to reach 4.9 percent in 2011. Two developments mark the outlook: the unrest in the region and the surge in global fuel and food prices. For most oil exporters, the expected increase in oil prices and production volumes will lead to higher growth in 2011 and stronger fiscal and external balances, notwithstanding recent increases in government spending. The oil exporters' combined external current account surplus is estimated to increase. The effects of the political events in Tunisia and Egypt have spread in varying degrees to the MENA oil exporters in the region, and many of these countries are responding with public spending and job-creation measures to alleviate social tensions. The social unrest also highlights the need to pursue fundamental economic reforms--social policy, fiscal management, governance, business environment, labor markets, and financial sector access to facilitate more inclusive economic growth. While the MENA countries are generally divided into two sub-regions such as "oil exporters" and "oil importers" in the economic literature, the authors will deal with only the MENA oil exporters in this work. The negative effects of the global crisis in these countries on growth, inflation, current account balance, budget balance, and finally financial sector will be reviewed in this work and the expectations and the developments which occurred after the crisis in these countries will be dealt with especially in the context of the IMF reports. 展开更多
关键词 global crisis the Middle East and North Africa (mena) mena oil exporters
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Mena表达及SNPs与胃癌遗传易感性及预后 被引量:3
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作者 王密 张声 +5 位作者 任彩虹 陈祥娜 王行富 黎三艳 陈余朋 曾赛凡 《中国肿瘤临床》 CAS CSCD 北大核心 2013年第16期965-970,共6页
目的:探讨Mena表达与胃癌侵袭转移的相关性及SNPs与胃癌遗传易感性的关系。方法:制作模拟胃癌侵袭转移过程的组织芯片,免疫组化染色检测Mena蛋白的表达。PCR—LDR技术检测Mena基因5个SNPs位点多态性并行测序验证。结果:胃腺癌中Men... 目的:探讨Mena表达与胃癌侵袭转移的相关性及SNPs与胃癌遗传易感性的关系。方法:制作模拟胃癌侵袭转移过程的组织芯片,免疫组化染色检测Mena蛋白的表达。PCR—LDR技术检测Mena基因5个SNPs位点多态性并行测序验证。结果:胃腺癌中Mena表达上调,肠型与混合型胃癌高于弥漫型,并与胃癌侵袭转移负相关,Mena高表达者预后好。Mena基因SNP位点rs3795443的188例对照组等位基因A、G的频率分别为91.0%和9.0%,胃癌病例组等位基因A、c的频率为82.4%和17.6%;AA、A/G和GG的基因型频率在对照组分别为81.9%、18.1%和0,而在病例组为68.35%、28.09%和3.56%,差异具有统计学意义(OR=2.1489,95%CI:1.4607~3.1613,P〈0.01)。5个SNPs位点的基因型和等位基因频率与胃癌术后生存时间均无明显相关性。结论:胃癌Mena表达升高,组织学类型的维持以及侵袭转移与其表达密切相关,高表达者预后好。MenaSNPrs3795443位点携带等位基因G的GG和A/G基因型个体的胃癌患病风险提高,提示检测该位点基因型有助于评估胃癌的遗传易感性。 展开更多
关键词 胃癌 mena表达 SNP 传易感性 预后
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大肠杆菌menA敲除对CoQ积累的影响研究
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作者 刘永青 任琳 张子锋 《生物技术通报》 CAS CSCD 北大核心 2015年第12期207-213,共7页
通过同源重组敲除大肠杆菌的men A基因,增加菌体Co Q合成量,用于构建Co Q高产菌株。以p KD4质粒为模板,PCR扩增kanr片段;在p KD46的辅助下,kanr片段转化大肠杆菌,利用抗生素筛选和PCR验证重组子;以紫外诱变菌为对照,发酵men A基因敲除菌... 通过同源重组敲除大肠杆菌的men A基因,增加菌体Co Q合成量,用于构建Co Q高产菌株。以p KD4质粒为模板,PCR扩增kanr片段;在p KD46的辅助下,kanr片段转化大肠杆菌,利用抗生素筛选和PCR验证重组子;以紫外诱变菌为对照,发酵men A基因敲除菌株,分析Co Q种类和产量变化。成功获得men A基因敲除菌株,Co Q种类不变,产量增加约为38%。首次敲除men A基因,改良株Co Q产量得到提高,达到预期目标。 展开更多
关键词 大肠杆菌 基因敲除 mena基因 COQ 同源重组
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The Middle Eastern Eagle: How the MENA Region Can Rise
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作者 Anna Cornelia Beyer 《International Relations and Diplomacy》 2014年第2期144-149,共6页
The Middle Eastern and North African (MENA) region has the potential to rise if it puts the recent changes to good use. Political changes in some countries might have opened the way for liberalization, which in turn... The Middle Eastern and North African (MENA) region has the potential to rise if it puts the recent changes to good use. Political changes in some countries might have opened the way for liberalization, which in turn again might facilitate democratization. Both will benefit the economic development of the region. So far, economic growth is hindered by excessive and ineffective public sectors, which do not provide sufficient opportunities for the growing young population. Privatization of some services and a general liberalization of the markets might help bring the young workforce into employment and in the long run will fuel an economic upswing. 展开更多
关键词 Middle Eastern and North African (mena) economic DEMOCRACY
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Mena、Her-2蛋白在乳腺癌组织中的表达和意义
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作者 张青山 徐正顺 郑海燕 《陕西医学杂志》 CAS 2011年第5期613-615,633,共4页
目的:探讨乳腺癌组织中Mena和人表皮生长因子受体2(Her-2)蛋白的表达和意义。方法:采用免疫组化方法检测60例乳腺癌组织和15例正常乳腺组织中Mena和Her-2蛋白的表达,同时分析其与临床病理资料的关系。结果:Mena蛋白在乳腺癌组织中的阳... 目的:探讨乳腺癌组织中Mena和人表皮生长因子受体2(Her-2)蛋白的表达和意义。方法:采用免疫组化方法检测60例乳腺癌组织和15例正常乳腺组织中Mena和Her-2蛋白的表达,同时分析其与临床病理资料的关系。结果:Mena蛋白在乳腺癌组织中的阳性表达率为73.3%(44/60),Her-2蛋白的阳性表达率为38.3%(23/60),均明显高于在正常乳腺组织中(0.0%)的表达(P<0.05),且均与临床分期及腋淋巴结转移密切相关(P<0.05),与患者年龄、肿瘤大小、雌激素受体(ER)、孕激素受体(PR)无关(P>0.05);Mena与Her-2蛋白的表达有相关性(r=0.398,P<0.01)。结论:Mena和Her-2可能在乳腺癌细胞的浸润和转移中起重要作用;检测Mena和Her-2蛋白的表达可能对判断乳腺癌的恶性程度、浸润转移潜能及预后判断有重要参考价值。 展开更多
关键词 乳腺肿瘤/病理学 蛋白质类/代谢 受体 表皮生长因子/代谢 免疫组织化学 @mena
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Comparison of WRF Model Physics Parameterizations over the MENA-CORDEX Domain 被引量:3
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作者 George Zittis Panos Hadjinicolaou Jos Lelieveld 《American Journal of Climate Change》 2014年第5期490-511,共22页
We investigated the performance of 12 different physics configurations of the climate version of the Weather, Research and Forecasting (WRF) Model over the Middle East and North Africa (MENA) domain. Possible combinat... We investigated the performance of 12 different physics configurations of the climate version of the Weather, Research and Forecasting (WRF) Model over the Middle East and North Africa (MENA) domain. Possible combinations among two Planetary Boundary Layer (PBL), three Cumulus (CUM) and two Microphysics (MIC) schemes were tested. The 2-year simulations (December 1988-November 1990) have been compared with gridded observational data and station measurements for several variables, including total precipitation and maximum and minimum 2-meter air temperature. An objective ranking method of the 12 different simulations and the selection procedure of the best performing configuration for the MENA domain are based on several statistical metrics and carried out for relevant sub-domains and individual stations. The setup for cloud microphysics is found to have the strongest impact on temperature biases while precipitation is most sensitive to the cumulus parameterization scheme and mainly in the tropics. 展开更多
关键词 WRF Physics PARAMETERIZATIONS Regional Climate Modeling Sensitivity mena CORDEX
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Linking Environmental Water Scarcity and Options for Adaptation in the MENA Region
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作者 Bachar Ibrahim Henry Mensah 《Journal of Water Resource and Protection》 2017年第4期378-392,共15页
Contamination of surface and underground water by sea level rise, surface runoff, and land use activities such as industrial and agricultural activities can lead to water scarcity. Water could be available and accessi... Contamination of surface and underground water by sea level rise, surface runoff, and land use activities such as industrial and agricultural activities can lead to water scarcity. Water could be available and accessible but not suitable for human use. In the Middle East and North Africa (MENA) region countries, the agriculture sector depends massively on water for farming activities, which consumes about 80% of the available water resources. In this context, the issue of environmental water scarcity is under highlighted, though the use of this term itself is still lacking in an international context (FAO). Meanwhile, the international goal of universal access to clean freshwater is included in global development targets (SDGs). This study provides some insights and deepens our understanding on environmental water scarcity, particularly MEN-A region countries. This review paper begins with an introduction to water scarcity and continues with a discussion of environmental issues associated with water scarcity in MENA region countries. Finally, we suggest some adaptive measures in two distinct areas such as agriculture sectors and policy makers and conclude that the lack of implementation of this particular term is hindering sustainable development in MENA region countries. 展开更多
关键词 ADAPTATION mena Climate Change WATER SCARCITY WATER Quality Environment
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Water Shortage in MENA Region: An Interdisciplinary Overview and a Suite of Practical Solutions
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作者 Anas Zyadin 《Journal of Water Resource and Protection》 2013年第4期49-58,共10页
The chronic water shortage in the Middle East North Africa (MENA) region is a perplexing issue, undoubtedly because various operational sectors, multi-institutions and stakeholders are inextricably interconnected. In ... The chronic water shortage in the Middle East North Africa (MENA) region is a perplexing issue, undoubtedly because various operational sectors, multi-institutions and stakeholders are inextricably interconnected. In the light of climate variability and the unprecedented population growth rate, the per capita water resources and biocapacity will continue plummeting, and the demand-gap will seriously expand. Existing water quantification agreements have been deemed inefficient to solve the problem of naturally diminishing water resources and thus require immediate re-assembling. Most scholarly endeavors, including key international organizations, NGOs, and “Think Tank” policy briefs have limitedly addressed water shortage in contexts of regional politics, mass media, and, importantly, from social psychology perspectives. Therefore, a thorough analysis and interdisciplinary approach is required to find a feasible and suitable framework of solutions and from a multi-perspective podium. A synthesis of cross-sectorial bottlenecks that are crucial to water management is presented, and a suite of practical recommendations are introduced to water authorities and governments. This study argues that in the shadow of the region’s political instability, the clash of ideologies and its repercussions, and issues of national security and sovereignty, regional cooperation on water issues remain prognostications. In this essence, governments of MENA countries are urged to develop measures to substantially increase the water supply through innovative approaches. Such measures include enhancing the capacities of water harvesting, maximizing the storage capacities of the built dams, and deploying groundwater recharge techniques. Furthermore, seawater and brackish water desalination through clean energy technologies is a contemporary solution with socio-economic and multiple benefits. Multi-billion water projects might not be suitable approach in the absence of external funding and the aforementioned hurdles. Further research is required to address the social economics, and environmental aspects of desalination and the socio-economic feasibility of privatizing drinking water utilities and price polarization. 展开更多
关键词 Water Conflicts RENEWABLE Energy mena REGION INTERDISCIPLINARY Approach
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Mena蛋白与TES蛋白在肿瘤侵袭转移中的作用研究进展
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作者 齐学袖 《药学研究》 CAS 2019年第6期351-354,共4页
Mena蛋白是Ena/VASP家族蛋白之一,在细胞伪足的形成和延伸、细胞的运动中起着重要的作用;TES是一种细胞黏附分子,在细胞外抑制肿瘤细胞的迁移和侵袭。近年来研究表明,肿瘤细胞伪足的形成和延伸以及细胞黏附是影响肿瘤细胞迁移和侵袭的... Mena蛋白是Ena/VASP家族蛋白之一,在细胞伪足的形成和延伸、细胞的运动中起着重要的作用;TES是一种细胞黏附分子,在细胞外抑制肿瘤细胞的迁移和侵袭。近年来研究表明,肿瘤细胞伪足的形成和延伸以及细胞黏附是影响肿瘤细胞迁移和侵袭的主要原因,本文通过探讨Mena蛋白与TES蛋白相互作用对肿瘤细胞伪足和细胞运动能力以及细胞黏附的影响,阐明Mena蛋白与TES蛋白在肿瘤细胞迁移和侵袭过程中的作用及分子机制,为肿瘤转移患者分子靶向治疗提供新的治疗靶点策略和思路。 展开更多
关键词 mena蛋白 TES蛋白 相互作用 肿瘤 侵袭 转移
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2004年12月26日印尼8.7级强震后江苏地区同震效应分析 被引量:19
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作者 郑江蓉 徐桂明 +1 位作者 李鸿宇 唐振芳 《防灾减灾工程学报》 CSCD 2005年第1期105-113,共9页
在2004年12月26日印尼苏门答腊北部发生8.7级强烈地震后,对江苏省地震前兆观测资料进行了及时的清理和分析,发现凡是能监测地下应力活动的前兆观测手段,如应变、地倾斜、水温和水位,在这次特大地震的震后都记录到了显著的异常,且异常的... 在2004年12月26日印尼苏门答腊北部发生8.7级强烈地震后,对江苏省地震前兆观测资料进行了及时的清理和分析,发现凡是能监测地下应力活动的前兆观测手段,如应变、地倾斜、水温和水位,在这次特大地震的震后都记录到了显著的异常,且异常的表现形式各不相同,将这些异常列出并浅析之,以期对进一步深入研究这次地震对我国未来地震趋势的影响有所帮助。 展开更多
关键词 印尼8.7级强烈地震 前兆观测 同震异常
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肉与肉制品中挥发性盐基氮测定方法的改进 被引量:18
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作者 邵金良 杨芳 +2 位作者 杜丽娟 樊建麟 束继红 《肉类研究》 2009年第10期58-60,共3页
为提高肉与肉制品中挥发性盐基氮测定速度,进行了肉与肉制品中挥发性盐基氮(GB/T5009.44-2003)国家标准测定方法的改进试验:①采用BUCHI-K360型全自动定氮仪测定法替代半微量定氮法;②采用碳酸钾溶液代替氧化镁混悬液作为碱性试剂。通... 为提高肉与肉制品中挥发性盐基氮测定速度,进行了肉与肉制品中挥发性盐基氮(GB/T5009.44-2003)国家标准测定方法的改进试验:①采用BUCHI-K360型全自动定氮仪测定法替代半微量定氮法;②采用碳酸钾溶液代替氧化镁混悬液作为碱性试剂。通过改进法的重复性试验,回收率试验和两种测定方法的差异显著性试验结果表明,①改进法的方法重复性试验的RSD小于1.0%;②改进法的回收率和加标回收率在98.39%~l00.72%之间。③改进法与标准法测定结果的t值0.319<。该法适合肉与肉制品中挥发性盐基氮的快速测定。 展开更多
关键词 肉与肉制品 挥发性盐基氮 检测方法 改进
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A群脑膜炎奈瑟菌多糖IgG抗体检测试剂研制 被引量:6
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作者 肖丽君 赵恩宏 +1 位作者 孔健 郝志敏 《中国公共卫生》 CAS CSCD 北大核心 2008年第3期344-346,共3页
目的研制检测A群脑膜炎奈瑟菌荚膜多糖IgG抗体的酶联免疫吸附试验(ELISA)检测试剂。方法以CTAB、酚、乙醇从A群脑膜炎奈瑟菌培养上清中提取荚膜多糖(MenA PS),将多糖与卵清蛋白(EA)以还原氨基法偶联,并以Sepharose CL-4B纯化。优... 目的研制检测A群脑膜炎奈瑟菌荚膜多糖IgG抗体的酶联免疫吸附试验(ELISA)检测试剂。方法以CTAB、酚、乙醇从A群脑膜炎奈瑟菌培养上清中提取荚膜多糖(MenA PS),将多糖与卵清蛋白(EA)以还原氨基法偶联,并以Sepharose CL-4B纯化。优化反应条件,建立以偶联物MenA PS-EA为包被抗原检测A群脑膜炎奈瑟菌多糖IgG抗体的间接ELISA法,并与血清杀菌力试验(SBA)比较。结果高效液相色谱检测MenA PS-EA结合物纯度为81.50%。试剂具有良好重复性(变异系数CV=4.26%~5.30%);37℃放置7d、4℃放置12个月,试剂的灵敏度不变,具有优良的稳定性;分别用该试剂和SBA法检测192份血清,试剂相对于血清杀菌力试验的灵敏度为96.91%,特异度为90.00%,一致性为95.83%,统计学分析表明,2种检测方法之间差异无统计学意义。结论以纯化MenA PS-EA作为包被抗原建立的A群脑膜炎奈瑟菌多糖特异性IgG抗体间接ELISA检测试剂具有可行性,为进一步研究及开发细菌多糖类抗体诊断试剂提供了可借鉴的方法。 展开更多
关键词 酶联免疫吸附试验(ELISA) 偶联物 抗A群脑膜炎奈瑟菌荚膜多糖IgG抗体
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蚁群优化与模糊聚类结合的文本聚类研究 被引量:3
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作者 王飞 张德贤 +1 位作者 韩金淑 陶永波 《计算机工程与应用》 CSCD 北大核心 2010年第32期126-129,共4页
针对模糊文本聚类算法(FCM)对输入顺序以及初始点敏感的问题,提出了一种使用蚁群优化的模糊聚类算法(FACA)。该算法采用蚁群聚类算法(ACA)找到聚类的初始中心点,以解决模糊聚类的输入顺序以及初始点敏感等问题。模糊文本聚类算法的线性... 针对模糊文本聚类算法(FCM)对输入顺序以及初始点敏感的问题,提出了一种使用蚁群优化的模糊聚类算法(FACA)。该算法采用蚁群聚类算法(ACA)找到聚类的初始中心点,以解决模糊聚类的输入顺序以及初始点敏感等问题。模糊文本聚类算法的线性复杂度使其更便于在计算机实现。与经典的基本模糊聚类以及蚁群聚类在真实数据集上仿真相比较,结果表明经蚁群优化过的模糊聚类算法(FACA)效果更有效,更适合应用于大型的数据集。 展开更多
关键词 文本聚类 模糊聚类(FCM) 蚁群聚类(ACA) 蚁群优化的模糊聚类算法(FACA)
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2015年中东北非地区油气上游发展回顾与展望 被引量:4
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作者 郝琦 侯明扬 《国际石油经济》 2016年第3期78-83,共6页
2015年,中东北非地区油气上游发展出现新看点。一是北非地区勘探活动取得较大突破,获得一批包括埃及Zohr巨型气田在内的勘探突破;不同区域内原油和天然气开发活动呈现差异化发展趋势。二是伊斯兰国极端势力肆虐、伊朗核制裁预期终结等... 2015年,中东北非地区油气上游发展出现新看点。一是北非地区勘探活动取得较大突破,获得一批包括埃及Zohr巨型气田在内的勘探突破;不同区域内原油和天然气开发活动呈现差异化发展趋势。二是伊斯兰国极端势力肆虐、伊朗核制裁预期终结等一系列地缘政治事件持续影响该区域石油市场。三是多个产油国出台政策措施鼓励上游油气工业发展。四是国际石油公司大幅调整在该地区的投资水平及并购策略。预计2016年地缘政治风险仍将极大地影响中东北非地区上游油气发展;地中海东部区域将成为新一轮勘探活动的热点;沙特阿拉伯瓦西特天然气开发项目等一批大型油气开发工程预期将取得进展;国际石油公司也将进一步调整在该地区的投资和并购策略。 展开更多
关键词 中东北非地区油气工业 勘探开发 地缘政治风险 并购策略 财税政策 差异化
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Youth Role in the Arab Spring 被引量:1
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作者 Anahita Motazed Rad 《Journalism and Mass Communication》 2012年第6期691-700,共10页
Middle East and North Africa (MENA) has been experiencing a unique demographic transition in the world especially after September 11, whilst, its social, political and economic structures have considerably remained ... Middle East and North Africa (MENA) has been experiencing a unique demographic transition in the world especially after September 11, whilst, its social, political and economic structures have considerably remained inflexible and can hardly meet the increasing demands of employment among the youth whose expectations are raised through expansion in education. In spite of various common causes for the Arab uprisings, the paper spotlights the "Youth role" and its regarded issues of "Youth Bulge", "Education" and "Unemployment" with a glimpse to the overturned regimes of "Tunisia, Egypt, Libya, and Yemen". According to published statistics these countries are among the countries with the highest rate of youth as working age population in MENA. Therefore, the paper is to present the importance and impact of youth as a social parameter in challenging political structure of the countries in the MENA and leading to topple their political systems. Thus, the paper reasons the MENA political upheavals, in general, and the mentioned countries' uprisings, in particular, can not be well understood disregarding to natural tensions between economic, population structures, and political demographic challenges. This is to be done drawing on data from different international institutions. The intervened variables such as "ethnicity, race, religion and sexuality" and international parameters have not been considered. 展开更多
关键词 political upheavals UPRISING youth bulge education UNEMPLOYMENT Middle East and North Africa(mena)
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中国与中东地区经贸合作问题及其对策分析
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作者 罗晓斐 邹建华 《改革与战略》 北大核心 2011年第8期168-170,共3页
文章通过对中国与中东地区经贸合作问题的分析,提出了维护良性外交关系、建立竞争协调管理机制、深化产业结构升级以及开展文化教育领域交流四方面具有较强操作性的政策建议。
关键词 中东 经贸合作 对策
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再论对立面的统一
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作者 沧南 《湘潭大学学报(哲学社会科学版)》 CSSCI 北大核心 2010年第4期117-120,共4页
长期以来,我们在哲学教学和科研中,总是把统一和斗争的关系看作是相对和绝对的关系。其实,就矛盾的根本属性来说,统一性和斗争性都是无条件的、永久的,因而都是绝对的。就现实的具体的事物矛盾来说,统一和斗争都是有条件的、暂时的、过... 长期以来,我们在哲学教学和科研中,总是把统一和斗争的关系看作是相对和绝对的关系。其实,就矛盾的根本属性来说,统一性和斗争性都是无条件的、永久的,因而都是绝对的。就现实的具体的事物矛盾来说,统一和斗争都是有条件的、暂时的、过渡的,因而都是相对的。建国六十年来,哪一次斗争不是有条件的、暂时的、过渡的?把统一和斗争、统一性和斗争性的关系,概括为相对和绝对、相对性和绝对性的关系,在理论上是说不通的,在实践上是有害的。矛盾的统一和斗争都是相对的,没有统一就没有斗争,斗争不是目的,是为统一服务的。 展开更多
关键词 统一和斗争 相对和绝对 手段和目的
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哺乳动物肌动蛋白调节蛋白在肿瘤进展和转移中的作用
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作者 王密 《中国现代医生》 2011年第23期32-33,共2页
哺乳动物肌动蛋白调节蛋白enabled(Mena)是近年来发现的新基因,在多种肿瘤中过表达。Mena与细胞运动性和黏附性的调节相关。Mena的过表达诱导细胞膜突起和增加肿瘤细胞对基质的降解活性,增加体内癌细胞的细胞能动性,促进癌细胞的侵袭和... 哺乳动物肌动蛋白调节蛋白enabled(Mena)是近年来发现的新基因,在多种肿瘤中过表达。Mena与细胞运动性和黏附性的调节相关。Mena的过表达诱导细胞膜突起和增加肿瘤细胞对基质的降解活性,增加体内癌细胞的细胞能动性,促进癌细胞的侵袭和转移。本文对其生化结构、在正常和肿瘤组织中的表达定位以其在肿瘤发生发展中的作用研进行综述。 展开更多
关键词 mena 肿瘤 侵袭 转移
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碘酸钾和碘化钾对大鼠肝脏SIRT1 mRNA表达的影响
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作者 曹晓晓 徐菁 +4 位作者 刘列钧 王海燕 李秀维 王建强 谷云有 《中国科技信息》 2013年第8期139-140,共2页
目的:观察不同剂量的碘酸钾和碘化钾对大鼠肝脏SIRT1基因表达的影响。方法:根据喂养碘剂和剂量不同将Wistar大鼠随机分为8组,即:适碘组(KI、KIO3),10倍高碘组(10KI、10KIO3)、50倍高碘组(50KI、50KIO3),100倍高碘组(100KI、100KIO3)。... 目的:观察不同剂量的碘酸钾和碘化钾对大鼠肝脏SIRT1基因表达的影响。方法:根据喂养碘剂和剂量不同将Wistar大鼠随机分为8组,即:适碘组(KI、KIO3),10倍高碘组(10KI、10KIO3)、50倍高碘组(50KI、50KIO3),100倍高碘组(100KI、100KIO3)。喂养半年后,利用实时荧光定量PCR(Real-time PCR)分析大鼠肝脏SIRT1基因表达水平。结果:适碘组中,SIRT1在KI组中的mRNA表达量高于KIO3组,P<0.05;10倍剂量组中,SIRT1在10KI组中的基因表达水平明显高于10KIO3,P<0.01;50倍和100倍剂量组中,SIRT1的基因表达量在两种不同碘剂组中没有统计学差异,P>0.05;不论摄入何种碘剂,SIRT1在高剂量碘组中的基因表达量均高于适碘组。结论:高剂量的碘化剂和碘酸钾均可上调大鼠肝脏SIRT1基因表达量,肝脏SIRT1基因的表达上调可能是机体改善高碘致高脂血症的一种重要的分子机制。 展开更多
关键词 碘酸钾 碘化钾 调节因子沉默调节蛋白1 MRNA表达
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The Relative Deprivation Theory and Yemen's Uprising
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作者 Anahita Motazed Rad Bahman Maleki 《Sociology Study》 2013年第9期678-683,共6页
The political upheavals in the Arab world during 2011 challenged the political status quo and have irrevocably paved the way toward transformation in the Middle East and North Africa (MENA), The longstanding structu... The political upheavals in the Arab world during 2011 challenged the political status quo and have irrevocably paved the way toward transformation in the Middle East and North Africa (MENA), The longstanding structural impediments to equitable growth and social justice afflicting the Arab world came to a head through a combination of persistently poverty, high unemployment, particularly among educated youth, rampant corruption, deficit of democratic governance, and essential freedoms. Yemen is the third country of the Middle Eastern countries which turmoil sparked in. All the uprisings connote of social, political and economic discontent and frustration. The main question and issue of this paper is to answer: What conditions breed change to Yemen? The paper spotlights "relative deprivation" of Ted Robert Gurr as the most relevant theory to illustrate roots of the Yemen uprising. Relative deprivation theory holds that instead of an absolute standard deprivation, a gap between expectations and reality leads men to political violence. Therefore, this study is to utilize relative deprivation theory to explain how socio-economic shortages (such as high unemployment and education, along with poverty) and political inefficiencies of the Yemen's authoritarian regime led to public and collective discontent and upheaval. The intervened variables such as "ethnicity, race, religion, and sexuality" and international parameters have not been considered, 展开更多
关键词 Middle East and North Africa (mena) Yemen's upheaval deprivation theory AUTHORITARIANISM socio-economic shortages FRUSTRATION
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