Frailty is a state of late life decline and vulnerability, typified by physical weakness and decreased physiologic reserve. The epidemiology and pathophysiology of frailty share features with those of cardiovascular d...Frailty is a state of late life decline and vulnerability, typified by physical weakness and decreased physiologic reserve. The epidemiology and pathophysiology of frailty share features with those of cardiovascular disease. Gait speed can be used as a measure of frailty and is a powerful predictor of mortality. Advancing age is a potent risk factor for cardiovascular disease and has been associated with an increased risk of adverse outcomes. Older adults comprise approximately half of cardiac surgery patients, and account for nearly 80% of the major complications and deaths following surgery. The ability of traditional risk models to predict mortality and major morbidity in older patients being considered for cardiac surgery may improve if frailty, as measured by gait speed, is included in their assessment. It is possible that in the future frailty assessment may assist in choosing among therapies （e.g., surgical vs. percutaneous aortic valve replacement for patients with aortic stenosis）.展开更多
AIM:To investigate perception of natural orifice transluminal endoscopic surgery(NOTES)as a potential technique for appendectomy.METHODS:One hundred patients undergoing endoscopy and 100 physicians were given a questi...AIM:To investigate perception of natural orifice transluminal endoscopic surgery(NOTES)as a potential technique for appendectomy.METHODS:One hundred patients undergoing endoscopy and 100 physicians were given a questionnaire describing in detail the techniques of NOTES and laparoscopic appendectomy.They were asked about the reasons for their preference,choice of orifice,and extent of complication risk they were willing to accept.RESULTS:Fifty patients(50%)and only 21 physicians(21%)preferred NOTES(P<0.001).Patients had previously heard of NOTES less frequently(7%vs73%,P<0.001)and had undergone endoscopy more frequently(88%vs 36%,P<0.001)than physicians.Absence of hernia was the most common reason for NOTES preference in physicians(80%vs 44%,P= 0.003),whereas reduced pain was the most common reason in patients(66%vs 52%).Physicians were more likely to refuse NOTES as a novel and unsure technique(P<0.001)and having an increased risk of infection(P<0.001).The preferred access site in both groups was colon followed by stomach,with vagina being rarely preferred.In multivariable modeling,those with high-school education[odds ratio(OR):2.68,95% confidence interval(CI):1.23-5.83]and prior colonoscopy(OR:2.10,95%CI:1.05-4.19)were more likely to prefer NOTES over laparoscopic appendectomy.There was a steep decline in NOTES preference with increased rate of procedural complications.Male patients were more likely to consent to their wives vaginal NOTES appendectomy than male physicians(P=0.02).CONCLUSION:The preference of NOTES for appendectomy was greater in patients than physicians and was related to reduced pain and absence of hernia rather than lack of scarring.展开更多
Despite the tremendous effort made by industry and academia,we are still searching for metrics that can characterize Cyberspace and system security risks. In this paper,we study the class of security risks that are in...Despite the tremendous effort made by industry and academia,we are still searching for metrics that can characterize Cyberspace and system security risks. In this paper,we study the class of security risks that are inherent to the dependence structure in software with vulnerabilities and exhibit a "cascading" effect. We present a measurement framework for evaluating these metrics,and report a preliminary case study on evaluating the dependence-induced security risks in the Apache HTTP Server. The experiment results show that our framework can not only clearly analyze the root cause of the security risks but also quantitatively evaluate the attack consequence of the risks.展开更多
A new method for submarine pipeline routing risk quantitative analysis was provided, and the study was developed from qualitative analysis to quantitative analysis.The characteristics of the potential risk of the subm...A new method for submarine pipeline routing risk quantitative analysis was provided, and the study was developed from qualitative analysis to quantitative analysis.The characteristics of the potential risk of the submarine pipeline system were considered, and grey-mode identification theory was used. The study process was composed of three parts: establishing the indexes system of routing risk quantitative analysis, establishing the model of grey-mode identification for routing risk quantitative analysis, and establishing the standard of mode identification result. It is shown that this model can directly and concisely reflect the hazard degree of the routing through computing example, and prepares the routing selection for the future.展开更多
Forecasting The Advertising investment risk of Sporting goods is very important which can provide the decision support for top manager. In this paper, we presented an optimized support vector machine （OSVM） to predi...Forecasting The Advertising investment risk of Sporting goods is very important which can provide the decision support for top manager. In this paper, we presented an optimized support vector machine （OSVM） to predict Advertising investment risk of Sporting goods. Experimental results show that the prediction accuracy improved by the proposed method.展开更多
The purpose of this paper is to give a selective survey on recent progress in random metric theory and its applications to conditional risk measures.This paper includes eight sections.Section 1 is a longer introductio...The purpose of this paper is to give a selective survey on recent progress in random metric theory and its applications to conditional risk measures.This paper includes eight sections.Section 1 is a longer introduction,which gives a brief introduction to random metric theory,risk measures and conditional risk measures.Section 2 gives the central framework in random metric theory,topological structures,important examples,the notions of a random conjugate space and the Hahn-Banach theorems for random linear functionals.Section 3 gives several important representation theorems for random conjugate spaces.Section 4 gives characterizations for a complete random normed module to be random reflexive.Section 5 gives hyperplane separation theorems currently available in random locally convex modules.Section 6 gives the theory of random duality with respect to the locally L0-convex topology and in particular a characterization for a locally L0-convex module to be L0-pre-barreled.Section 7 gives some basic results on L0-convex analysis together with some applications to conditional risk measures.Finally,Section 8 is devoted to extensions of conditional convex risk measures,which shows that every representable L∞-type of conditional convex risk measure and every continuous Lp-type of convex conditional risk measure(1 ≤ p < +∞) can be extended to an L∞F(E)-type of σ,λ(L∞F(E),L1F(E))-lower semicontinuous conditional convex risk measure and an LpF(E)-type of T,λ-continuous conditional convex risk measure(1 ≤ p < +∞),respectively.展开更多
Let（Ω , E, P） be a probability space, F a sub-σ-algebra of E, L^p（E）（1 p ＋∞） the classical function space and LF^p（E） the L^0（F）-module generated by L^p（E）, which can be made into a random normed modul...Let（Ω , E, P） be a probability space, F a sub-σ-algebra of E, L^p（E）（1 p ＋∞） the classical function space and LF^p（E） the L^0（F）-module generated by L^p（E）, which can be made into a random normed module in a natural way. Up to the present time, there are three kinds of conditional risk measures, whose model spaces are L^∞（E）, L^p（E）（1 p ＋∞） and LF^p（E）（1 p ＋∞） respectively, and a conditional convex dual representation theorem has been established for each kind. The purpose of this paper is to study the relations among the three kinds of conditional risk measures together with their representation theorems. We first establish the relation between L^p（E） and LF^p（E）, namely LF^p（E） = Hcc（L^p（E））, which shows that LF^p（E）is exactly the countable concatenation hull of L^p（E）. Based on the precise relation, we then prove that every L^0（F）-convex L^p（E）-conditional risk measure（1 p ＋∞） can be uniquely extended to an L^0（F）-convex LF^p（E）-conditional risk measure and that the dual representation theorem of the former can also be regarded as a special case of that of the latter, which shows that the study of L^p-conditional risk measures can be incorporated into that of LF^p（E）-conditional risk measures. In particular, in the process we find that combining the countable concatenation hull of a set and the local property of conditional risk measures is a very useful analytic skill that may considerably simplify and improve the study of L^0-convex conditional risk measures.展开更多
文摘Frailty is a state of late life decline and vulnerability, typified by physical weakness and decreased physiologic reserve. The epidemiology and pathophysiology of frailty share features with those of cardiovascular disease. Gait speed can be used as a measure of frailty and is a powerful predictor of mortality. Advancing age is a potent risk factor for cardiovascular disease and has been associated with an increased risk of adverse outcomes. Older adults comprise approximately half of cardiac surgery patients, and account for nearly 80% of the major complications and deaths following surgery. The ability of traditional risk models to predict mortality and major morbidity in older patients being considered for cardiac surgery may improve if frailty, as measured by gait speed, is included in their assessment. It is possible that in the future frailty assessment may assist in choosing among therapies （e.g., surgical vs. percutaneous aortic valve replacement for patients with aortic stenosis）.
基金Supported by Grant NT 11234-3 of the Czech Ministry of Healththe Institutional Research Plan AV0Z10300504
文摘AIM:To investigate perception of natural orifice transluminal endoscopic surgery(NOTES)as a potential technique for appendectomy.METHODS:One hundred patients undergoing endoscopy and 100 physicians were given a questionnaire describing in detail the techniques of NOTES and laparoscopic appendectomy.They were asked about the reasons for their preference,choice of orifice,and extent of complication risk they were willing to accept.RESULTS:Fifty patients(50%)and only 21 physicians(21%)preferred NOTES(P<0.001).Patients had previously heard of NOTES less frequently(7%vs73%,P<0.001)and had undergone endoscopy more frequently(88%vs 36%,P<0.001)than physicians.Absence of hernia was the most common reason for NOTES preference in physicians(80%vs 44%,P= 0.003),whereas reduced pain was the most common reason in patients(66%vs 52%).Physicians were more likely to refuse NOTES as a novel and unsure technique(P<0.001)and having an increased risk of infection(P<0.001).The preferred access site in both groups was colon followed by stomach,with vagina being rarely preferred.In multivariable modeling,those with high-school education[odds ratio(OR):2.68,95% confidence interval(CI):1.23-5.83]and prior colonoscopy(OR:2.10,95%CI:1.05-4.19)were more likely to prefer NOTES over laparoscopic appendectomy.There was a steep decline in NOTES preference with increased rate of procedural complications.Male patients were more likely to consent to their wives vaginal NOTES appendectomy than male physicians(P=0.02).CONCLUSION:The preference of NOTES for appendectomy was greater in patients than physicians and was related to reduced pain and absence of hernia rather than lack of scarring.
基金supported by Natural Science Foundation of China under award No.61303024Natural Science Foundation of Jiangsu Province under award No.BK20130372+3 种基金National 973 Program of China under award No.2014CB340600National High Tech 863 Program of China under award No.2015AA016002supported by Natural Science Foundation of China under award No.61272452supported in part by ARO Grant # W911NF-12-1-0286 and NSF Grant #1111925
文摘Despite the tremendous effort made by industry and academia,we are still searching for metrics that can characterize Cyberspace and system security risks. In this paper,we study the class of security risks that are inherent to the dependence structure in software with vulnerabilities and exhibit a "cascading" effect. We present a measurement framework for evaluating these metrics,and report a preliminary case study on evaluating the dependence-induced security risks in the Apache HTTP Server. The experiment results show that our framework can not only clearly analyze the root cause of the security risks but also quantitatively evaluate the attack consequence of the risks.
文摘A new method for submarine pipeline routing risk quantitative analysis was provided, and the study was developed from qualitative analysis to quantitative analysis.The characteristics of the potential risk of the submarine pipeline system were considered, and grey-mode identification theory was used. The study process was composed of three parts: establishing the indexes system of routing risk quantitative analysis, establishing the model of grey-mode identification for routing risk quantitative analysis, and establishing the standard of mode identification result. It is shown that this model can directly and concisely reflect the hazard degree of the routing through computing example, and prepares the routing selection for the future.
文摘Forecasting The Advertising investment risk of Sporting goods is very important which can provide the decision support for top manager. In this paper, we presented an optimized support vector machine （OSVM） to predict Advertising investment risk of Sporting goods. Experimental results show that the prediction accuracy improved by the proposed method.
基金supported by National Natural Science Foundation of China (Grant No.10871016)
文摘The purpose of this paper is to give a selective survey on recent progress in random metric theory and its applications to conditional risk measures.This paper includes eight sections.Section 1 is a longer introduction,which gives a brief introduction to random metric theory,risk measures and conditional risk measures.Section 2 gives the central framework in random metric theory,topological structures,important examples,the notions of a random conjugate space and the Hahn-Banach theorems for random linear functionals.Section 3 gives several important representation theorems for random conjugate spaces.Section 4 gives characterizations for a complete random normed module to be random reflexive.Section 5 gives hyperplane separation theorems currently available in random locally convex modules.Section 6 gives the theory of random duality with respect to the locally L0-convex topology and in particular a characterization for a locally L0-convex module to be L0-pre-barreled.Section 7 gives some basic results on L0-convex analysis together with some applications to conditional risk measures.Finally,Section 8 is devoted to extensions of conditional convex risk measures,which shows that every representable L∞-type of conditional convex risk measure and every continuous Lp-type of convex conditional risk measure(1 ≤ p < +∞) can be extended to an L∞F(E)-type of σ,λ(L∞F(E),L1F(E))-lower semicontinuous conditional convex risk measure and an LpF(E)-type of T,λ-continuous conditional convex risk measure(1 ≤ p < +∞),respectively.
基金supported by National Natural Science Foundation of China(Grant Nos.11171015 and 11301568)
文摘Let（Ω , E, P） be a probability space, F a sub-σ-algebra of E, L^p（E）（1 p ＋∞） the classical function space and LF^p（E） the L^0（F）-module generated by L^p（E）, which can be made into a random normed module in a natural way. Up to the present time, there are three kinds of conditional risk measures, whose model spaces are L^∞（E）, L^p（E）（1 p ＋∞） and LF^p（E）（1 p ＋∞） respectively, and a conditional convex dual representation theorem has been established for each kind. The purpose of this paper is to study the relations among the three kinds of conditional risk measures together with their representation theorems. We first establish the relation between L^p（E） and LF^p（E）, namely LF^p（E） = Hcc（L^p（E））, which shows that LF^p（E）is exactly the countable concatenation hull of L^p（E）. Based on the precise relation, we then prove that every L^0（F）-convex L^p（E）-conditional risk measure（1 p ＋∞） can be uniquely extended to an L^0（F）-convex LF^p（E）-conditional risk measure and that the dual representation theorem of the former can also be regarded as a special case of that of the latter, which shows that the study of L^p-conditional risk measures can be incorporated into that of LF^p（E）-conditional risk measures. In particular, in the process we find that combining the countable concatenation hull of a set and the local property of conditional risk measures is a very useful analytic skill that may considerably simplify and improve the study of L^0-convex conditional risk measures.
