目的:探讨移植胚胎数和着床胚胎数与妊娠早期血清β-hCG值的关系。方法:回顾性分析IVF/ICSI新鲜胚胎移植后820个宫内妊娠周期,根据移植胚胎数及移植后35 d B超显示的妊娠囊数分组,比较移植14 d、18 d血清β-hCG水平及其上升幅度。结果:...目的:探讨移植胚胎数和着床胚胎数与妊娠早期血清β-hCG值的关系。方法:回顾性分析IVF/ICSI新鲜胚胎移植后820个宫内妊娠周期,根据移植胚胎数及移植后35 d B超显示的妊娠囊数分组,比较移植14 d、18 d血清β-hCG水平及其上升幅度。结果:不同移植胚胎数相同妊娠囊数组间比较血清β-hCG差异无统计学意义(P>0.05);妊娠早期血清β-hCG水平:三妊娠囊组>双妊娠囊组>单妊娠囊组,差异有统计学意义(P<0.05);血清β-hCG上升幅度各组比较无统计学意义(P>0.05)。结论:移植胚胎数对妊娠早期血清β-hCG无直接影响;着床胚胎数影响妊娠早期血清β-hCG水平。妊娠囊越多,其hCG水平就越高。展开更多
To determine whether increasing the number of embryos transferred beyond five increases pregnancy rates in women aged > 40 years. Design: Retrospective analysis of cycles performed between January 1998 and July 200...To determine whether increasing the number of embryos transferred beyond five increases pregnancy rates in women aged > 40 years. Design: Retrospective analysis of cycles performed between January 1998 and July 2003. Setting: University-affiliated teaching hospital. Patient(s): Women aged > 40 years undergoing a fresh cycle with a day- 3 ET (n = 863). Intervention(s): None. Main Outcome Measure(s): Pregnancy, bio-chemical pregnancy,miscarriage rates, number of viable fetuses at 12 weeks’ gestation, live birth rates, and number of babies delivered. Result(s): Compared with patients with fewer than five embryos transferred, those having five or more embryos transferred had significantly increased pregnancy rates and live birth rates, more viable fetuses at 12 weeks, and significantly decreased miscarriage rates. None of these outcome variables differed between the five-embryo and more-than-five-embryogroups. There were no differences in outcome when only five embryos were transferred, regardless of whether five or more than five embryos were available. The number of embryos transferred did not significantly influence multiple birth rates. Conclusion(s): The present study demonstrates that in women aged > 40 years, five embryos is the optimum number to transfer, and transferring more than five does not confer any additional benefit to clinical outcome.展开更多
文摘目的:探讨移植胚胎数和着床胚胎数与妊娠早期血清β-hCG值的关系。方法:回顾性分析IVF/ICSI新鲜胚胎移植后820个宫内妊娠周期,根据移植胚胎数及移植后35 d B超显示的妊娠囊数分组,比较移植14 d、18 d血清β-hCG水平及其上升幅度。结果:不同移植胚胎数相同妊娠囊数组间比较血清β-hCG差异无统计学意义(P>0.05);妊娠早期血清β-hCG水平:三妊娠囊组>双妊娠囊组>单妊娠囊组,差异有统计学意义(P<0.05);血清β-hCG上升幅度各组比较无统计学意义(P>0.05)。结论:移植胚胎数对妊娠早期血清β-hCG无直接影响;着床胚胎数影响妊娠早期血清β-hCG水平。妊娠囊越多,其hCG水平就越高。
文摘To determine whether increasing the number of embryos transferred beyond five increases pregnancy rates in women aged > 40 years. Design: Retrospective analysis of cycles performed between January 1998 and July 2003. Setting: University-affiliated teaching hospital. Patient(s): Women aged > 40 years undergoing a fresh cycle with a day- 3 ET (n = 863). Intervention(s): None. Main Outcome Measure(s): Pregnancy, bio-chemical pregnancy,miscarriage rates, number of viable fetuses at 12 weeks’ gestation, live birth rates, and number of babies delivered. Result(s): Compared with patients with fewer than five embryos transferred, those having five or more embryos transferred had significantly increased pregnancy rates and live birth rates, more viable fetuses at 12 weeks, and significantly decreased miscarriage rates. None of these outcome variables differed between the five-embryo and more-than-five-embryogroups. There were no differences in outcome when only five embryos were transferred, regardless of whether five or more than five embryos were available. The number of embryos transferred did not significantly influence multiple birth rates. Conclusion(s): The present study demonstrates that in women aged > 40 years, five embryos is the optimum number to transfer, and transferring more than five does not confer any additional benefit to clinical outcome.
