Objective To explore the relationship between connexin 43 and acupoints and meridians. Methods we detected one major skin gap junction connexin （connexin43, Cx43） in meridians and acupoints, and studied the expressi...Objective To explore the relationship between connexin 43 and acupoints and meridians. Methods we detected one major skin gap junction connexin （connexin43, Cx43） in meridians and acupoints, and studied the expression of Cx43 in Zusanli （足三里 ST 36） acupoints compared with control non-acupoint regions in rats after acupuncture treatments. The expression of Cx43 was detected by using immunohisto- chemistry, immunoblotting, and RT-PCR for Cx43 protein and mRNA level. Results The results showed much more abundant Cx43 expression in some cells in the skin and subcutaneous tissue of rat at ST 36 acupoints and bladder and kidney meridians than that of in the controls. The mRNA and protein levels of Cx43 in acupoints were significantly higher than those of in the control points in non-acupuncture groups and even more so after acupuncture treatments. Conclusion Our research implied that connexins and gap junctions could have a close relationship to acupoints and meridians, and gap junctional intercellular communication might play an important role in the effect of acupuncture.展开更多
Objective To explore the effects of sliding-cup with different parameters on energy metabolism in the body by observing the effect of sliding-cup along the governor vessel on transcutaneous partial pressures of oxygen...Objective To explore the effects of sliding-cup with different parameters on energy metabolism in the body by observing the effect of sliding-cup along the governor vessel on transcutaneous partial pressures of oxygen and carbon dioxide in Mìngmén（命门 GV 4） in sub-healthy people. Methods A total of 10 sub-healthy adults at rest were observed and sliding-cup along the governor vessel were conducted with three different parameters, jar-pressure of –0.01~ –0.02 MPa with sliding-cup for 5 min, jar-pressure of –0.02~ –0.03 MPa with sliding-cup for 5 min and jar-pressure of –0.02~ –0.03 MPa with slidingcup for 3 min. Peri Flux System5000 PF5040 module was employed to monitor the changes of transcutaneous partial pressures of oxygen（tcp O2） and carbon dioxide（tcp CO2） in GV 4 at 0 min, 5 min, 10 min, 15 min, 20 min, 25 min and 30 min after sliding-cup with above different interventions in sub-healthy subjects. Results After sliding-cup, tcp O2 increased at first and then decreased over time; there was no difference in tcp O2 after sliding-cupping with different parameters（all P0.05）. After sliding-cup, tcp CO2 decreased; there was no difference in tcp CO2 after sliding-cup with different parameters（all P0.05）. Conclusion Sliding-cup has a sustained effect on the body and can speed up the energy metabolism in the body.展开更多
Objective： To observe the clinical effects of aligned needling therapy for lumbar intervertebral disc herniation （LIDH）. Methods： A total of 80 cases with LIDH in conformity with the inclusion criteria were random...Objective： To observe the clinical effects of aligned needling therapy for lumbar intervertebral disc herniation （LIDH）. Methods： A total of 80 cases with LIDH in conformity with the inclusion criteria were randomly divided into a treatment group or a control group by their visit order, 40 cases in each group. The points from the Governor Vessel, L1-L5 Jiaji （EX-B 2） points, from the first lateral line of the Bladder Meridian, Huantiao （GB 30）, Weizhong （BL 40） and Yanglingquan （GB 34） were selected for acupuncture in the treatment group. Shenshu （BL 23）, Dachangshu （BL 25）, Ashi （Extra） points and Weizhong （BL 40） were used for routine acupuncture in the control group. The clinical effects of the two groups after 2-course treatments and recurrence rates three months later were observed. The pain severity before and after treatments was assessed by visual analog scale （VAS）. The improvement of the patient＇s pathological situation was evaluated by the performance assessment of lumbar disease treatment from Japanese Orthopedic Association （JOA）. Results： After the treatment for two courses, there was no dropped-out case in the two groups. The curative rates and total effective rates were respectively 32.5% and 92.5% in the treatment group versus respectively 12.5% and 82.5% in the control group. The differences in the curative rates and total effective rates between the two groups were statistically significant （both P〈0.01）. After the treatment, VAS and JOA scores remarkably declined in the patients of the two groups, with statistical differences in comparison with those of the same group before treatment （both P〈0.05）. In follow-up check of three months, the recurrence rate was 10.7% in the cured and remarkably effective cases in the treatment group and was 29.4% in the control group. The recurrence rates of the two groups were statistically different （P〈0.05）. Conclusion： The aligned needling technique is remarkable in the clinical effects, obvious in the analgesic effects and low in the recurrence rate in the treatment of LIDH.展开更多
Acupuncture anesthesia is a technique by partially or completely replacing anesthetics with acupuncture in surgery based on the traditional acupuncture analgesia mechanism.It emerged in the 1950s,went viral in the 197...Acupuncture anesthesia is a technique by partially or completely replacing anesthetics with acupuncture in surgery based on the traditional acupuncture analgesia mechanism.It emerged in the 1950s,went viral in the 1970s and then gradually fell into decline.In the recent years,this technique has regained attention and further research.Acupuncture anesthesia can be classified as either pure acupuncture anesthesia or acupuncture-medication combined anesthesia.To expand the application of this technique,a patient with non-ST elevation acute coronary syndrome in urgent need of percutaneous coronary intervention (PCI) received pure acupuncture anesthesia because of an allergy to lidocaine,and the operation went successfully.This is the first time that pure acupuncture anesthesia and coronary arteriography were combined,which is of great significance in further study and development of acupuncture anesthesia.展开更多
基金supported by grants from National Natural Science Foundation of China (No .90209009)National Basic Research Program(No .2006CB504502)~~
文摘Objective To explore the relationship between connexin 43 and acupoints and meridians. Methods we detected one major skin gap junction connexin （connexin43, Cx43） in meridians and acupoints, and studied the expression of Cx43 in Zusanli （足三里 ST 36） acupoints compared with control non-acupoint regions in rats after acupuncture treatments. The expression of Cx43 was detected by using immunohisto- chemistry, immunoblotting, and RT-PCR for Cx43 protein and mRNA level. Results The results showed much more abundant Cx43 expression in some cells in the skin and subcutaneous tissue of rat at ST 36 acupoints and bladder and kidney meridians than that of in the controls. The mRNA and protein levels of Cx43 in acupoints were significantly higher than those of in the control points in non-acupuncture groups and even more so after acupuncture treatments. Conclusion Our research implied that connexins and gap junctions could have a close relationship to acupoints and meridians, and gap junctional intercellular communication might play an important role in the effect of acupuncture.
基金Suported by Tianjin Municipal Administration of Traditional Chinese Medicine:11028
文摘Objective To explore the effects of sliding-cup with different parameters on energy metabolism in the body by observing the effect of sliding-cup along the governor vessel on transcutaneous partial pressures of oxygen and carbon dioxide in Mìngmén（命门 GV 4） in sub-healthy people. Methods A total of 10 sub-healthy adults at rest were observed and sliding-cup along the governor vessel were conducted with three different parameters, jar-pressure of –0.01~ –0.02 MPa with sliding-cup for 5 min, jar-pressure of –0.02~ –0.03 MPa with sliding-cup for 5 min and jar-pressure of –0.02~ –0.03 MPa with slidingcup for 3 min. Peri Flux System5000 PF5040 module was employed to monitor the changes of transcutaneous partial pressures of oxygen（tcp O2） and carbon dioxide（tcp CO2） in GV 4 at 0 min, 5 min, 10 min, 15 min, 20 min, 25 min and 30 min after sliding-cup with above different interventions in sub-healthy subjects. Results After sliding-cup, tcp O2 increased at first and then decreased over time; there was no difference in tcp O2 after sliding-cupping with different parameters（all P0.05）. After sliding-cup, tcp CO2 decreased; there was no difference in tcp CO2 after sliding-cup with different parameters（all P0.05）. Conclusion Sliding-cup has a sustained effect on the body and can speed up the energy metabolism in the body.
基金supported by Project of Science and Technology Development Program of Tengzhou City,Shandong Province(No.201310002)Science and Technology Project for Graduate Student Tutor in Institution of Higher Education of Gansu Province(No.11006-08)~~
文摘Objective： To observe the clinical effects of aligned needling therapy for lumbar intervertebral disc herniation （LIDH）. Methods： A total of 80 cases with LIDH in conformity with the inclusion criteria were randomly divided into a treatment group or a control group by their visit order, 40 cases in each group. The points from the Governor Vessel, L1-L5 Jiaji （EX-B 2） points, from the first lateral line of the Bladder Meridian, Huantiao （GB 30）, Weizhong （BL 40） and Yanglingquan （GB 34） were selected for acupuncture in the treatment group. Shenshu （BL 23）, Dachangshu （BL 25）, Ashi （Extra） points and Weizhong （BL 40） were used for routine acupuncture in the control group. The clinical effects of the two groups after 2-course treatments and recurrence rates three months later were observed. The pain severity before and after treatments was assessed by visual analog scale （VAS）. The improvement of the patient＇s pathological situation was evaluated by the performance assessment of lumbar disease treatment from Japanese Orthopedic Association （JOA）. Results： After the treatment for two courses, there was no dropped-out case in the two groups. The curative rates and total effective rates were respectively 32.5% and 92.5% in the treatment group versus respectively 12.5% and 82.5% in the control group. The differences in the curative rates and total effective rates between the two groups were statistically significant （both P〈0.01）. After the treatment, VAS and JOA scores remarkably declined in the patients of the two groups, with statistical differences in comparison with those of the same group before treatment （both P〈0.05）. In follow-up check of three months, the recurrence rate was 10.7% in the cured and remarkably effective cases in the treatment group and was 29.4% in the control group. The recurrence rates of the two groups were statistically different （P〈0.05）. Conclusion： The aligned needling technique is remarkable in the clinical effects, obvious in the analgesic effects and low in the recurrence rate in the treatment of LIDH.
基金National Natural Science Foundation of China(国家自然科学基金项目,81573796,81503440)%Shanghai Shenkang Hospital Development Center:Three-year Plan for Promoting Clinical Skills and Innovations in Municipal Hospitals(上海申康医院发展中心-促进市级医院临床技能与临床创新能力三年行动计划,16CR1031B)%Shanghai Clinical Cooperation Pilot Project of Chinese and Western Medicine(上海市中西医临床协作试点建设项目,ZY (2018-2020)-FWTX-1011)
文摘Acupuncture anesthesia is a technique by partially or completely replacing anesthetics with acupuncture in surgery based on the traditional acupuncture analgesia mechanism.It emerged in the 1950s,went viral in the 1970s and then gradually fell into decline.In the recent years,this technique has regained attention and further research.Acupuncture anesthesia can be classified as either pure acupuncture anesthesia or acupuncture-medication combined anesthesia.To expand the application of this technique,a patient with non-ST elevation acute coronary syndrome in urgent need of percutaneous coronary intervention (PCI) received pure acupuncture anesthesia because of an allergy to lidocaine,and the operation went successfully.This is the first time that pure acupuncture anesthesia and coronary arteriography were combined,which is of great significance in further study and development of acupuncture anesthesia.
