目的:探究加味半夏泻心汤联合四联疗法治疗幽门螺杆菌(Hp)相关性慢性胃炎脾胃湿热型的临床疗效。方法:将2022年7月~2024年7月随州市中医医院脾胃病科科诊治的40例Hp感染后脾胃湿热型慢性胃炎患者作为研究对象,随机将研究对象分为对照组...目的:探究加味半夏泻心汤联合四联疗法治疗幽门螺杆菌(Hp)相关性慢性胃炎脾胃湿热型的临床疗效。方法:将2022年7月~2024年7月随州市中医医院脾胃病科科诊治的40例Hp感染后脾胃湿热型慢性胃炎患者作为研究对象,随机将研究对象分为对照组(四联疗法)和研究组(四联疗法合用加味半夏泻心汤),每组各20例。观察两组患者临床症状治疗有效率、Hp根除率及中医证候积分的变化情况。结果:研究组(四联疗法合用加味半夏泻心汤组)证候治疗有效率、Hp根除率均高于对照组(四联疗法组),差异有统计学意义(P Objective: To explore the clinical efficacy of modified Banxia Xiexin Tang combined with quadruple therapy in the treatment of Helicobacter pylori (Hp)-related chronic gastritis with spleen stomach damp heat type. Methods: Forty patients with chronic gastritis of spleen and stomach damp heat type after Hp infection treated by the type of Spleen and Stomach Diseases from July 2022 to July 2024 were selected as the study subjects. The study subjects were randomly divided into a control group (quadruple therapy) and a study group (quadruple therapy combined with modified Banxia Xiexin Tang), with 20 cases in each group. Observe the changes in the effective rate of clinical symptom treatment, Hp eradication rate, and TCM syndrome score between two groups of patients. Results: The treatment efficacy and Hp eradication rate of the research group (the combination of quadruple therapy and modified Banxia Xiexin Tang group) were higher than those in the other one (the quadruple therapy group);The above indicators in the research group (the combination of quadruple therapy and modified Banxia Xiexin Tang group) were lower than those in the other group (quadruple therapy group), the difference was statistically significant (P < 0.05). Conclusion: In the treatment of Hp related spleen stomach damp heat chronic gastritis, the combination of modified Banxia Xiexin Tang and quadruple therapy can better eradicate Hp, rapidly improve patients' relevant clinical symptoms, enhance their quality of life, and have reliable therapeutic effects. It is recommended for application.展开更多
目的:通过文献计量学方法,分析近30年幽门螺杆菌(Hp)感染与肝脏疾病相关性研究的热点内容和发展趋势,为后续深入探究该领域提供参考。方法:检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、Web of Science核心数据集(WOSCC)1993年1月1日...目的:通过文献计量学方法,分析近30年幽门螺杆菌(Hp)感染与肝脏疾病相关性研究的热点内容和发展趋势,为后续深入探究该领域提供参考。方法:检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、Web of Science核心数据集(WOSCC)1993年1月1日至2023年6月15日Hp感染与肝脏疾病相关性研究的文献。应用VOSviewer 1.6.19及CiteSpace 6.2.R2软件对纳入文献的发文国家、机构、作者、本研究领域的热点和前沿方向进行统计分析。结果:中文数据库共纳入文献517篇,WOSCC数据库纳入文献168篇。年总发文量呈波动上升趋势,自2016年始该领域发文量呈下降趋势;中国和美国是该领域论文高产出国家;吉林大学中日联谊医院及埃及国家知识库(EKB)为该领域的核心机构;关键词分析显示Hp、非酒精性脂肪性肝病(NAFLD)、胰岛素抵抗、慢性乙型肝炎、肝纤维化是现阶段的研究热点。结论:近年来Hp感染与肝脏疾病相关性研究的关注度趋冷,尚未形成核心作者和机构群;该领域研究热点主要集中在Hp感染-胰岛素抵抗-NAFLD-代谢综合征以及Hp感染-肝炎-肝纤维化-肝硬化两大研究方向,更全面、深入地探索Hp在肝脏疾病发病中的作用机制,解决现有的临床争议问题是本领域未来研究的趋势。展开更多
文摘目的:探究加味半夏泻心汤联合四联疗法治疗幽门螺杆菌(Hp)相关性慢性胃炎脾胃湿热型的临床疗效。方法:将2022年7月~2024年7月随州市中医医院脾胃病科科诊治的40例Hp感染后脾胃湿热型慢性胃炎患者作为研究对象,随机将研究对象分为对照组(四联疗法)和研究组(四联疗法合用加味半夏泻心汤),每组各20例。观察两组患者临床症状治疗有效率、Hp根除率及中医证候积分的变化情况。结果:研究组(四联疗法合用加味半夏泻心汤组)证候治疗有效率、Hp根除率均高于对照组(四联疗法组),差异有统计学意义(P Objective: To explore the clinical efficacy of modified Banxia Xiexin Tang combined with quadruple therapy in the treatment of Helicobacter pylori (Hp)-related chronic gastritis with spleen stomach damp heat type. Methods: Forty patients with chronic gastritis of spleen and stomach damp heat type after Hp infection treated by the type of Spleen and Stomach Diseases from July 2022 to July 2024 were selected as the study subjects. The study subjects were randomly divided into a control group (quadruple therapy) and a study group (quadruple therapy combined with modified Banxia Xiexin Tang), with 20 cases in each group. Observe the changes in the effective rate of clinical symptom treatment, Hp eradication rate, and TCM syndrome score between two groups of patients. Results: The treatment efficacy and Hp eradication rate of the research group (the combination of quadruple therapy and modified Banxia Xiexin Tang group) were higher than those in the other one (the quadruple therapy group);The above indicators in the research group (the combination of quadruple therapy and modified Banxia Xiexin Tang group) were lower than those in the other group (quadruple therapy group), the difference was statistically significant (P < 0.05). Conclusion: In the treatment of Hp related spleen stomach damp heat chronic gastritis, the combination of modified Banxia Xiexin Tang and quadruple therapy can better eradicate Hp, rapidly improve patients' relevant clinical symptoms, enhance their quality of life, and have reliable therapeutic effects. It is recommended for application.
文摘目的:通过文献计量学方法,分析近30年幽门螺杆菌(Hp)感染与肝脏疾病相关性研究的热点内容和发展趋势,为后续深入探究该领域提供参考。方法:检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、Web of Science核心数据集(WOSCC)1993年1月1日至2023年6月15日Hp感染与肝脏疾病相关性研究的文献。应用VOSviewer 1.6.19及CiteSpace 6.2.R2软件对纳入文献的发文国家、机构、作者、本研究领域的热点和前沿方向进行统计分析。结果:中文数据库共纳入文献517篇,WOSCC数据库纳入文献168篇。年总发文量呈波动上升趋势,自2016年始该领域发文量呈下降趋势;中国和美国是该领域论文高产出国家;吉林大学中日联谊医院及埃及国家知识库(EKB)为该领域的核心机构;关键词分析显示Hp、非酒精性脂肪性肝病(NAFLD)、胰岛素抵抗、慢性乙型肝炎、肝纤维化是现阶段的研究热点。结论:近年来Hp感染与肝脏疾病相关性研究的关注度趋冷,尚未形成核心作者和机构群;该领域研究热点主要集中在Hp感染-胰岛素抵抗-NAFLD-代谢综合征以及Hp感染-肝炎-肝纤维化-肝硬化两大研究方向,更全面、深入地探索Hp在肝脏疾病发病中的作用机制,解决现有的临床争议问题是本领域未来研究的趋势。
