The asults of forty-twe pabents witll AMI(≥60 yeas 26 cases) treated with intravenous urokinasc(Group A) were reported. Another 168 patientswith AMI wthout urokinase administration in thesame period (Group B) were se...The asults of forty-twe pabents witll AMI(≥60 yeas 26 cases) treated with intravenous urokinasc(Group A) were reported. Another 168 patientswith AMI wthout urokinase administration in thesame period (Group B) were selectcd for compari-son. The coronary artery recanalization rate ofGroup A paticnts were 61.9% with no significantdifferencc between those aged ≤60 years and≥60 yeas (P>0.05). The hospitalization mor-tality was significantly lowcr in Group A (4.8%)than in Group B(22.6%, P<0.001). In paticntsaged ≥60 years, the hospitalization mortality wilssigniticantly lower in Grolip A (7.7%) than inGroup B too(27.1 %, P<0.01). Four Group A pa-tients complicateed with mild haemorrhage andtwo with hypotention. The effcctiveness and safetyor thrombolytic therapy in eldly patients withAMI were discussed.展开更多
目的对经过大剂量尿激酶静脉溶栓治疗的心源性脑栓塞患者的神经功能进行观察,研究对其的疗效以及改善作用。方法将我院的109例心源性脑栓塞患者作为研究对象,随机的分为两组,观察组和对照组。观察组为56例,采用100-150万单位的尿激酶并...目的对经过大剂量尿激酶静脉溶栓治疗的心源性脑栓塞患者的神经功能进行观察,研究对其的疗效以及改善作用。方法将我院的109例心源性脑栓塞患者作为研究对象,随机的分为两组,观察组和对照组。观察组为56例,采用100-150万单位的尿激酶并加用100 m L的生理盐水中静脉溶栓进行治疗,而对照组为53例,使用抗血小板聚集或是抗凝进行治疗。结果经过观察,两组患者进行治疗后,其缺血性脑卒中的神经功能缺损明显减少,并且其中的差异具有统计学意义(P<0.05),观察组的治疗效果要比对照组中的治疗效果好,P<0.05,但两组的出血转化发生率没有明显的差异。结论在进行大剂量尿激酶静脉溶栓治疗的心源性脑栓塞患者的神经功能能够有效地改善,要比采用抗血小板聚集或是抗凝进行治疗的方法具有优势。展开更多
文摘The asults of forty-twe pabents witll AMI(≥60 yeas 26 cases) treated with intravenous urokinasc(Group A) were reported. Another 168 patientswith AMI wthout urokinase administration in thesame period (Group B) were selectcd for compari-son. The coronary artery recanalization rate ofGroup A paticnts were 61.9% with no significantdifferencc between those aged ≤60 years and≥60 yeas (P>0.05). The hospitalization mor-tality was significantly lowcr in Group A (4.8%)than in Group B(22.6%, P<0.001). In paticntsaged ≥60 years, the hospitalization mortality wilssigniticantly lower in Grolip A (7.7%) than inGroup B too(27.1 %, P<0.01). Four Group A pa-tients complicateed with mild haemorrhage andtwo with hypotention. The effcctiveness and safetyor thrombolytic therapy in eldly patients withAMI were discussed.
文摘目的对经过大剂量尿激酶静脉溶栓治疗的心源性脑栓塞患者的神经功能进行观察,研究对其的疗效以及改善作用。方法将我院的109例心源性脑栓塞患者作为研究对象,随机的分为两组,观察组和对照组。观察组为56例,采用100-150万单位的尿激酶并加用100 m L的生理盐水中静脉溶栓进行治疗,而对照组为53例,使用抗血小板聚集或是抗凝进行治疗。结果经过观察,两组患者进行治疗后,其缺血性脑卒中的神经功能缺损明显减少,并且其中的差异具有统计学意义(P<0.05),观察组的治疗效果要比对照组中的治疗效果好,P<0.05,但两组的出血转化发生率没有明显的差异。结论在进行大剂量尿激酶静脉溶栓治疗的心源性脑栓塞患者的神经功能能够有效地改善,要比采用抗血小板聚集或是抗凝进行治疗的方法具有优势。
