为方便了解Pola-BR方案在真实世界中治疗复发/难治弥漫大B细胞淋巴瘤的疗效及安全性,本文分析总结了9项回顾性真实世界研究,结果表明使用Pola-BR方案的真实世界数据虽没有GO29365试验的结果理想,但仍然是治疗R/R DLBCL的一种比较好的选...为方便了解Pola-BR方案在真实世界中治疗复发/难治弥漫大B细胞淋巴瘤的疗效及安全性,本文分析总结了9项回顾性真实世界研究,结果表明使用Pola-BR方案的真实世界数据虽没有GO29365试验的结果理想,但仍然是治疗R/R DLBCL的一种比较好的选择。To facilitate understanding of the efficacy and safety of the Pola-BR in the treatment of relapsed/ refractory diffuse large B-cell lymphoma in the real world, this article analyzes and summarizes nine retrospective real-world studies, and the results suggest that real-world data using the Pola-BR regimen, although not as promising as the results of the GO29365 trial, is still a better option for the treatment of R/R DLBCL.展开更多
原发性睾丸淋巴瘤(PTL)是一种罕见且具有侵袭性的结外淋巴瘤,可分为原发和继发两类。1) 原发性:以睾丸肿块为原发症状或主要症状,无其他结外器官受累,经病理确诊为DLBCL。2) 继发性:系统性累及睾丸的DLBCL为继发睾丸DLBCL,以原发性常见...原发性睾丸淋巴瘤(PTL)是一种罕见且具有侵袭性的结外淋巴瘤,可分为原发和继发两类。1) 原发性:以睾丸肿块为原发症状或主要症状,无其他结外器官受累,经病理确诊为DLBCL。2) 继发性:系统性累及睾丸的DLBCL为继发睾丸DLBCL,以原发性常见。目前PTl-DLBCL的相关文献报道较少且发病机制未明,推荐的综合治疗方案仍存在较高的结外复发风险。Primary Testicular Lymphoma (PTL) is a rare and invasive extranodal lymphoma, which can be divided into primary and secondary types. 1) Primary: Testicular mass is the primary symptom or the main symptom without other extranodal organ involvement, which is pathologically diagnosed as DLBCL. 2) Secondary: DLBCL with systemic involvement of the testis is secondary testicular DLBCL, which is common in primary. At present, there are few reports on PTl-DLBCL and the pathogenesis is unknown. The recommended comprehensive treatment still has a high risk of extranodal recurrence.展开更多
文摘为方便了解Pola-BR方案在真实世界中治疗复发/难治弥漫大B细胞淋巴瘤的疗效及安全性,本文分析总结了9项回顾性真实世界研究,结果表明使用Pola-BR方案的真实世界数据虽没有GO29365试验的结果理想,但仍然是治疗R/R DLBCL的一种比较好的选择。To facilitate understanding of the efficacy and safety of the Pola-BR in the treatment of relapsed/ refractory diffuse large B-cell lymphoma in the real world, this article analyzes and summarizes nine retrospective real-world studies, and the results suggest that real-world data using the Pola-BR regimen, although not as promising as the results of the GO29365 trial, is still a better option for the treatment of R/R DLBCL.
文摘原发性睾丸淋巴瘤(PTL)是一种罕见且具有侵袭性的结外淋巴瘤,可分为原发和继发两类。1) 原发性:以睾丸肿块为原发症状或主要症状,无其他结外器官受累,经病理确诊为DLBCL。2) 继发性:系统性累及睾丸的DLBCL为继发睾丸DLBCL,以原发性常见。目前PTl-DLBCL的相关文献报道较少且发病机制未明,推荐的综合治疗方案仍存在较高的结外复发风险。Primary Testicular Lymphoma (PTL) is a rare and invasive extranodal lymphoma, which can be divided into primary and secondary types. 1) Primary: Testicular mass is the primary symptom or the main symptom without other extranodal organ involvement, which is pathologically diagnosed as DLBCL. 2) Secondary: DLBCL with systemic involvement of the testis is secondary testicular DLBCL, which is common in primary. At present, there are few reports on PTl-DLBCL and the pathogenesis is unknown. The recommended comprehensive treatment still has a high risk of extranodal recurrence.
