Bionics （the imitation or abstraction of the ＂inventions＂ of nature） and, to an even greater extent, syn- thetic biology, will be as relevant to engineering development and industry as the silicon chip was over th...Bionics （the imitation or abstraction of the ＂inventions＂ of nature） and, to an even greater extent, syn- thetic biology, will be as relevant to engineering development and industry as the silicon chip was over the last 50 years. Chemical industries already use so-called ＂white biotechnology＂ for new processes, new raw materials, and more sustainable use of resources. Synthetic biology is also used for the devel- opment of second-generation biofuels and for harvesting the sun＇s energy with the help of tailor-made microorganisms or biometrically designed catalysts. The market potential for bionics in medicine, en- gineering processes, and DNA storage is huge. ＂Moonshot＂ projects are already aggressively focusing on diseases and new materials, and a US-led competition is currently underway with the aim of creating a thousand new molecules. This article describes a timeline that starts with current projects and then moves on to code engineering projects and their implications, artificial DNA, signaling molecules, and biological circuitry. Beyond these projects, one of the next frontiers in bionics is the design of synthetic metabolisms that include artificial food chains and foods, and the bioengineering of raw materials; all of which will lead to new insights into biological principles. Bioengineering will be an innovation motor just as digitalization is today. This article discusses pertinent examples of bioengineering, particularly the use of alternative carbon-based biofuels and the techniques and perils of cell modification. Big data, analytics, and massive storage are important factors in this next frontier. Although synthetic biology will be as pervasive and transformative in the next 50 years as digitization and the Intemet are today, its ap- plications and impacts are still in nascent stages. This article provides a general taxonomy in which the development of bioengineering is classified in five stages （DNA analysis, bio-circuits, minimal genomes, protocells, xenobiology） from the familiar to the unknown, with implications for safety and security, in- dustrial development, and the development of bioengineering and biotechnology as an interdisciplinary field. Ethical issues and the importance of a public debate about the consequences of bionics and syn- thetic biology are discussed.展开更多
Substitution boxes (S-Boxes) in advanced encryption standard (AES) are vulnerable to attacks bypower analysis.The general S-Boxes masking schemes in circuit level need to adjust the design flow andlibrary databases.Th...Substitution boxes (S-Boxes) in advanced encryption standard (AES) are vulnerable to attacks bypower analysis.The general S-Boxes masking schemes in circuit level need to adjust the design flow andlibrary databases.The masking strategies in algorithm level view each S-Box as an independent moduleand mask them respectively,which are costly in size and power for non-linear characteristic of S-Boxes.The new method uses dynamic inhomogeneous S-Boxes instead of traditional homogeneous S-Boxes,andarranges the S-Boxes randomly.So the power and data path delay of substitution unit become unpre-dictable.The experimental results demonstrate that this scheme takes advantages of the circuit character-istics of various S-Box implementations to eliminate the correlation between crypto operation and power.Itneeds less extra circuits and suits resource constrained applications.展开更多
基金国家自然科学基金(61772192)湖南省教育厅:2017年湖南省普通高等学校教学改革研究项目([2017]452号)+3 种基金湖南省教育厅:2016年度湖南省教育科学“十三五”规划项目(P6752)Project Supported by National Natural Science Foundation of China(61772192)Education Department of Hunan Province:2017 Teaching Reform Research Project of Colleges and Universities in Hunan Province([2017]452)Hunan Province Education Science Planing Project"13.5"of Hunan Education Department(P6752)
文摘Bionics （the imitation or abstraction of the ＂inventions＂ of nature） and, to an even greater extent, syn- thetic biology, will be as relevant to engineering development and industry as the silicon chip was over the last 50 years. Chemical industries already use so-called ＂white biotechnology＂ for new processes, new raw materials, and more sustainable use of resources. Synthetic biology is also used for the devel- opment of second-generation biofuels and for harvesting the sun＇s energy with the help of tailor-made microorganisms or biometrically designed catalysts. The market potential for bionics in medicine, en- gineering processes, and DNA storage is huge. ＂Moonshot＂ projects are already aggressively focusing on diseases and new materials, and a US-led competition is currently underway with the aim of creating a thousand new molecules. This article describes a timeline that starts with current projects and then moves on to code engineering projects and their implications, artificial DNA, signaling molecules, and biological circuitry. Beyond these projects, one of the next frontiers in bionics is the design of synthetic metabolisms that include artificial food chains and foods, and the bioengineering of raw materials; all of which will lead to new insights into biological principles. Bioengineering will be an innovation motor just as digitalization is today. This article discusses pertinent examples of bioengineering, particularly the use of alternative carbon-based biofuels and the techniques and perils of cell modification. Big data, analytics, and massive storage are important factors in this next frontier. Although synthetic biology will be as pervasive and transformative in the next 50 years as digitization and the Intemet are today, its ap- plications and impacts are still in nascent stages. This article provides a general taxonomy in which the development of bioengineering is classified in five stages （DNA analysis, bio-circuits, minimal genomes, protocells, xenobiology） from the familiar to the unknown, with implications for safety and security, in- dustrial development, and the development of bioengineering and biotechnology as an interdisciplinary field. Ethical issues and the importance of a public debate about the consequences of bionics and syn- thetic biology are discussed.
基金the National High Technology Research and Development Programme of China(No.2006AA01Z226)
文摘Substitution boxes (S-Boxes) in advanced encryption standard (AES) are vulnerable to attacks bypower analysis.The general S-Boxes masking schemes in circuit level need to adjust the design flow andlibrary databases.The masking strategies in algorithm level view each S-Box as an independent moduleand mask them respectively,which are costly in size and power for non-linear characteristic of S-Boxes.The new method uses dynamic inhomogeneous S-Boxes instead of traditional homogeneous S-Boxes,andarranges the S-Boxes randomly.So the power and data path delay of substitution unit become unpre-dictable.The experimental results demonstrate that this scheme takes advantages of the circuit character-istics of various S-Box implementations to eliminate the correlation between crypto operation and power.Itneeds less extra circuits and suits resource constrained applications.
