新生儿低氧性呼吸衰竭常见于早产儿和窒息新生儿等特定人群。吸入一氧化氮作为治疗手段,相比传统氧疗具有快速、靶向性强的优势。氧合指数作为评估呼吸功能的关键指标,可用于实时监测治疗效果。尽管一氧化氮治疗疗效显著,但其安全性和...新生儿低氧性呼吸衰竭常见于早产儿和窒息新生儿等特定人群。吸入一氧化氮作为治疗手段,相比传统氧疗具有快速、靶向性强的优势。氧合指数作为评估呼吸功能的关键指标,可用于实时监测治疗效果。尽管一氧化氮治疗疗效显著,但其安全性和不良反应仍需关注。本研究的意义在于深入分析吸入一氧化氮治疗新生儿低氧血症的研究进展,以及氧合指数作为关键指标的临床应用,以助于临床医生进行风险评估,最终提高新生儿的生存率和生活质量。Neonatal hypoxic respiratory failure frequently affects premature and asphyxiated newborns, characterized by hypoxemia and CO2 retention due to impaired respiratory function. Inhaled nitric oxide emerges as an effective treatment, offering rapid and targeted vasodilation of pulmonary vessels, improving oxygenation more efficiently than traditional oxygen therapy. The oxygenation index is a critical marker for assessing respiratory function and monitoring therapy effectiveness. Despite its proven efficacy, NO therapy presents safety concerns and potential adverse effects, which require careful monitoring. This study aims to analyze advancements in iNO treatment for neonatal hypoxemia and explore OI’s clinical application as a key indicator, ultimately assisting clinicians in risk assessment and enhancing neonatal survival and quality of life.展开更多
文摘新生儿低氧性呼吸衰竭常见于早产儿和窒息新生儿等特定人群。吸入一氧化氮作为治疗手段,相比传统氧疗具有快速、靶向性强的优势。氧合指数作为评估呼吸功能的关键指标,可用于实时监测治疗效果。尽管一氧化氮治疗疗效显著,但其安全性和不良反应仍需关注。本研究的意义在于深入分析吸入一氧化氮治疗新生儿低氧血症的研究进展,以及氧合指数作为关键指标的临床应用,以助于临床医生进行风险评估,最终提高新生儿的生存率和生活质量。Neonatal hypoxic respiratory failure frequently affects premature and asphyxiated newborns, characterized by hypoxemia and CO2 retention due to impaired respiratory function. Inhaled nitric oxide emerges as an effective treatment, offering rapid and targeted vasodilation of pulmonary vessels, improving oxygenation more efficiently than traditional oxygen therapy. The oxygenation index is a critical marker for assessing respiratory function and monitoring therapy effectiveness. Despite its proven efficacy, NO therapy presents safety concerns and potential adverse effects, which require careful monitoring. This study aims to analyze advancements in iNO treatment for neonatal hypoxemia and explore OI’s clinical application as a key indicator, ultimately assisting clinicians in risk assessment and enhancing neonatal survival and quality of life.
