The distribution of selenium\|containing proteins in the subcellular fractions of human liver components was treated by sodium dodecyl sulfate\|polyacrylamide gel electrophoresis (SDS\|PAGE) and hydride generation\|at...The distribution of selenium\|containing proteins in the subcellular fractions of human liver components was treated by sodium dodecyl sulfate\|polyacrylamide gel electrophoresis (SDS\|PAGE) and hydride generation\|atomic fluorescence spectrophotometry (HG\|AFS). About 24 kinds of Se\|containing proteins or protein subunits were found in subcellular fractions. Their molecular weights were mostly ranged from 20 to 30 kD and from 50 to 80 kD. Among them, about 61 kD and 21 kD Se\|containing proteins existed in each fraction with higher concentration. The 54 kD Se\|containing protein existed in nuclei, mitochondria, microsome and cytosol. The specific subcellular distributions of Se\|containing proteins suggest that Se could play specific important biological roles in each organelle.展开更多
来源于间叶组织的肿瘤称为肉瘤,原发性肝肉瘤极为罕见,约占原发性肝内恶性肿瘤的1.3%,包括淋巴肉瘤、血管肉瘤、平滑肌肉瘤等多种类型,肝脏未分化肉瘤又称胚胎肉瘤(undifferentiated embryonal sarcoma of liver,USL),好发于儿童及青...来源于间叶组织的肿瘤称为肉瘤,原发性肝肉瘤极为罕见,约占原发性肝内恶性肿瘤的1.3%,包括淋巴肉瘤、血管肉瘤、平滑肌肉瘤等多种类型,肝脏未分化肉瘤又称胚胎肉瘤(undifferentiated embryonal sarcoma of liver,USL),好发于儿童及青少年,成年病例极为罕见,我科于2006年曾收治1例USL患者,现报告如下。展开更多
肝脏未分化胚胎性肉瘤(undifferentiated embryonal sarcoma of the liver,UESL)是一种高度恶性的肿瘤,临床十分少见。UESL多发生于儿童,约占儿童肝原发恶性肿瘤的9%-13%,成年人罕见,常易误诊。现将我科收治的1例成人UESL患者...肝脏未分化胚胎性肉瘤(undifferentiated embryonal sarcoma of the liver,UESL)是一种高度恶性的肿瘤,临床十分少见。UESL多发生于儿童,约占儿童肝原发恶性肿瘤的9%-13%,成年人罕见,常易误诊。现将我科收治的1例成人UESL患者情况报告如下。展开更多
文摘The distribution of selenium\|containing proteins in the subcellular fractions of human liver components was treated by sodium dodecyl sulfate\|polyacrylamide gel electrophoresis (SDS\|PAGE) and hydride generation\|atomic fluorescence spectrophotometry (HG\|AFS). About 24 kinds of Se\|containing proteins or protein subunits were found in subcellular fractions. Their molecular weights were mostly ranged from 20 to 30 kD and from 50 to 80 kD. Among them, about 61 kD and 21 kD Se\|containing proteins existed in each fraction with higher concentration. The 54 kD Se\|containing protein existed in nuclei, mitochondria, microsome and cytosol. The specific subcellular distributions of Se\|containing proteins suggest that Se could play specific important biological roles in each organelle.
文摘来源于间叶组织的肿瘤称为肉瘤,原发性肝肉瘤极为罕见,约占原发性肝内恶性肿瘤的1.3%,包括淋巴肉瘤、血管肉瘤、平滑肌肉瘤等多种类型,肝脏未分化肉瘤又称胚胎肉瘤(undifferentiated embryonal sarcoma of liver,USL),好发于儿童及青少年,成年病例极为罕见,我科于2006年曾收治1例USL患者,现报告如下。
文摘慢性乙型和慢性丙型肝炎病人有不同的临床表现。我们先前报道了感染乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)的肝脏组织基因表达谱的差异,但二者各自的信号传导途径并未阐明。我们从256550份肝脏基因表达系列分析文库(serial analysis of gene expression,SAGE)中选取9614个克隆构建一个新的cDNA微阵列,比较了24例慢性乙型肝炎和23例慢性丙型肝炎病人的肝组织的基因表达谱;