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Knowledge Modeling and Institutional Memory at the University of Cape Coast: Examining Technology as a Mediator and Leadership Styles as a Moderator in Enhancing Administrative Efficiency
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作者 Harriette Nusrat Manu Eleanor Afua Onyame +2 位作者 Eunice Amoako Mensah Sarah Annim Sayibu Abdul-Gafaar 《Intelligent Information Management》 2025年第1期1-30,共30页
The integration of digital tools and effective knowledge management practices is critical for enhancing administrative efficiency and institutional continuity in higher education. This study investigates the relations... The integration of digital tools and effective knowledge management practices is critical for enhancing administrative efficiency and institutional continuity in higher education. This study investigates the relationships between knowledge modeling, institutional memory, leadership styles, technology, and administrative efficiency at the University of Cape Coast (UCC). The study sought to identify the challenges and opportunities in integrating digital tools into administrative processes and to provide actionable recommendations for improvement. A mixed-methods research design was employed, combining quantitative analysis using Partial Least Squares Structural Equation Modeling (PLS-SEM) with qualitative thematic analysis of interviews. The findings revealed key challenges, including resistance to change, fragmented knowledge repositories, and inadequate funding, alongside opportunities such as centralized knowledge systems, cost-effective open-source tools, and capacity-building initiatives. The study highlights the importance of strategic leadership, robust policies, and investments in digital infrastructure to enhance administrative practices. Policy implications include the need for clear digital transformation guidelines and leadership training to foster innovation and collaboration. Recommendations include investing in scalable digital tools, implementing comprehensive capacity-building programs, and promoting stakeholder engagement to drive successful digital integration. These insights provide a roadmap for UCC and similar institutions seeking to optimize administrative efficiency through digital transformation. 展开更多
关键词 Knowledge Management Institutional Memory Digital Integration Technology Adoption administrative Efficiency Leadership Styles Centralised Knowledge Repositories
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Women’s empowerment and food consumption:Evidence from female-headed households in Tanzania 被引量:1
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作者 Mosses Lufuke Xu Tian 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第2期457-467,共11页
Despite the growing recognition of women’s increasing role in the household and corresponding empowerment programs in sub-Saharan Africa,intensive research on the relationship between women’s influence and household... Despite the growing recognition of women’s increasing role in the household and corresponding empowerment programs in sub-Saharan Africa,intensive research on the relationship between women’s influence and household food consumption is minimal.Using the most recent(2017-2018)national household survey data from Tanzania,this study examined the influence of women’s empowerment on household food consumption.First,we compared the monthly consumption of eight food categories between female-headed households(FHHs)and male-headed households(MHHs)using both descriptive statistics and the propensity score matching(PSM)method.Furthermore,we adopted the two-stage Linear Expenditure System and Almost Ideal Demand System model(LES-AIDS)to estimate income and price elasticities for the two household types.The results show that FHHs consume bread and cereals,fish,oils and fats,vegetables,and confectionery(sugar,jam,honey,chocolate,etc.)more than MHHs.Moreover,FHHs have a significantly higher income elasticity of demand for all food groups than MHHs.They are also more price elastic than MHHs in meat,fish,oils,fats,sugar,jam,honey,chocolate,etc. 展开更多
关键词 women’s empowerment food consumption income elasticity price elasticity
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Construction of the Demonstration Area for the Inheritance and Development of Yimeng Red Culture Based on Digital Empowerment
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作者 MA Haiyang WANG Hui +2 位作者 ZHANG Chuanxin ZHANG Ying LIU Xiaomei 《Journal of Landscape Research》 2024年第5期77-80,共4页
Yimeng red culture is an important part of the excellent culture of the Chinese nation.It is of great practical significance and long-term strategic significance to build the demonstration area for the inheritance and... Yimeng red culture is an important part of the excellent culture of the Chinese nation.It is of great practical significance and long-term strategic significance to build the demonstration area for the inheritance and development of Yimeng red culture.Combining digital empowerment with the inheritance and development of Yimeng red culture is a new idea that conforms to the development of the times.In this paper,on the basis of combing Yimeng red cultural resources and combining with the current situation of inheritance and development of Yimeng red culture,the strategic layout and implementation approach of the demonstration area for the inheritance and development of Yimeng red culture were put forward from the perspective of digital empowerment. 展开更多
关键词 Digital empowerment Yimeng Red culture INHERITANCE Demonstration area
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Adjustment of Administrative Divisions and Upgrading of Industrial Structure in Hefei Metropolitan Area:Taking"Partitions of Chaohu"as a Quasi-natural Experiment
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作者 Yumin DING 《Asian Agricultural Research》 2024年第7期19-23,27,共6页
Administrative regions are an important environment for the operation of China's market economy.The relevant economic subjects cannot predict the policy of adjustment of administrative divisions and carry out cons... Administrative regions are an important environment for the operation of China's market economy.The relevant economic subjects cannot predict the policy of adjustment of administrative divisions and carry out conscious migration behavior,adjustment of administrative divisions can be regarded as a quasi-natural experiment.The three cities of Hefei,Wuhu,and Ma'anshan,which are directly related to the adjustment of the administrative division of Chaohu,are taken as the treatment group,and the seven adjacent cities of Lu'an,Huainan,Chuzhou,Bengbu,Anqing,Chizhou,and Tongling are taken as the control group.Differences-in-Differences method and relevant control variables affecting the upgrading of industrial structure are used to test.The test results show that"Partitions of Chaohu"has a significant industrial structure upgrading effect by promoting the optimization of spatial layout,the cross-regional flow of production factors and the effective management of Chaohu Lake Basin.At the same time,the increase of total retail sales of consumer goods,urban fixed assets investment,public utility expenses in science,education,culture and health,and population plays a significant positive role in promoting the upgrading of industrial structure,while foreign direct investment plays a certain inhibition role in the upgrading of industrial structure.In order to meet the ever-developing space demands and enhance the impact on surrounding areas,the Hefei metropolitan area should be driven by technological innovation,strengthen the integration of industrial chains,improve the business environment and transportation network,and continuously promote the upgrading of industrial structure and the formation and development of new productive forces. 展开更多
关键词 Adjustment of administrative divisions Upgrading of industrial structure Hefei metropolitan area Quasi-natural experiment
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Animation‐guided family empowerment program on perioperative care after neurosurgery:A randomized controlled trial for preventing respiratory complications
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作者 Yunfen Lv Ziwei Zhao +2 位作者 Xinyi Wu Yao Wang Shanshan Qiu 《Health Care Science》 2024年第3期141-150,共10页
Background:This study aimed to evaluate the effectiveness of using animation as education material for family empowerment program on perioperative care for caregivers whose children were to undergo neurosurgery.Method... Background:This study aimed to evaluate the effectiveness of using animation as education material for family empowerment program on perioperative care for caregivers whose children were to undergo neurosurgery.Methods:A total of 204 caregivers were randomly assigned to either the face‐to‐face oral nursing educated group(Oral Group)or the animation‐assisted nursing educated group(Animated Group).The nursing education primarily focused on instructing caregivers about the manual vibration method.The primary outcome of interest in this study was participants'knowledge level,collected by a 10‐item questionnaire.Secondary outcomes included child patients'clinical data,including hospitalization days,treatments,and signs of pneumonia.Results:Participants in the Animated Group exhibited significantly higher accuracy in perioperative care knowledge assessment,and patients in this group had a lower chance of requiring atomization therapy compared to the Oral Group.Conclusions:The animation‐assisted nursing education program effectively enhances pediatric caregivers'knowledge,reduces respiratory complications after surgery,and offers valuable insights for future studies on the use of such programs to instruct caregivers. 展开更多
关键词 empowerment PEDIATRIC perioperative care PNEUMONIA ANIMATION
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From Control to Empowerment:A Paradigm Shift in the Discourse of Educational Supervision
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作者 Jinhua Zhou Kai Zhang 《Journal of Contemporary Educational Research》 2024年第9期176-180,共5页
As educational reforms intensify and societal emphasis shifts towards empowerment,the traditional discourse paradigm of management and control in educational supervision faces growing challenges.This paper explores th... As educational reforms intensify and societal emphasis shifts towards empowerment,the traditional discourse paradigm of management and control in educational supervision faces growing challenges.This paper explores the transformation of this discourse paradigm through the lens of empowerment,analyzing its distinct characteristics,potential pathways,and effective strategies.This paper begins by reviewing the concept of empowerment and examining the current research landscape surrounding the discourse paradigm in educational supervision.Subsequently,we conduct a comparative analysis of the“control”and“empowerment”paradigms,highlighting their essential differences.This analysis illuminates the key characteristics of an empowerment-oriented approach to educational supervision,particularly its emphasis on dialogue,collaboration,participation,and,crucially,empowerment itself.Ultimately,this research advocates for a shift in educational supervision towards an empowerment-oriented discourse system.This entails a multi-pronged approach:transforming ingrained beliefs,embracing renewed pedagogical concepts,fostering methodological innovation,and optimizing existing mechanisms and strategies within educational supervision.These changes are proposed to facilitate the more effective alignment of educational supervision with the pursuit of high-quality education. 展开更多
关键词 Educational supervision Paradigm shift CONTROL empowerment
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Analysis of the Effect of Family-Centered Empowerment Model(FCEM)Health Education Through WeChat on Medication Compliance and Blood Pressure of Elderly Hypertensive Patients in Rural Areas
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作者 Yingying Yang Alita R.Conde 《Journal of Clinical and Nursing Research》 2024年第4期154-162,共9页
Objective: To validate the effectiveness of a Family-Centered Empowerment Model (FCEM) health education through WeChat on medication compliance and blood pressure among elderly hypertensive patients in rural areas. Me... Objective: To validate the effectiveness of a Family-Centered Empowerment Model (FCEM) health education through WeChat on medication compliance and blood pressure among elderly hypertensive patients in rural areas. Methods: One hundred and two rural elderly hypertensive patients aged 65-80 years were selected and randomly divided into an experimental and control group of 51 each. The control group implemented conventional health education, and the experimental group implemented FCEM health education through WeChat platform for 4 consecutive weeks. The Therapeutic Adherence Scale for Hypertensive Patients (TASHP) scores and blood pressure measurements were compared between and within the two groups. Results: After the intervention, there were significant differences in medication compliance and blood pressure between the two groups (P < 0.001). In the control group, before and after the intervention, there was a significant difference in medication compliance (P < 0.001), but no significant difference in blood pressure (P > 0.05). In the experimental group, there were significant differences in medication compliance and blood pressure before and after the intervention (P < 0.001). Conclusion: The FCEM health education through an online social platform significantly improved medication compliance and led to effective blood pressure control in rural elderly hypertensive patients. Therefore, as an effective, safe, and economical model, it is also necessary to explore its effectiveness in improving health problems in other chronic diseases and other age groups. 展开更多
关键词 Family support empowerment HYPERTENSION ELDERLY Medication compliance
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Exploration of Curriculum Reform in the Context of Digital Empowerment:Taking the“Class Management”Course in the Primary Education Major of Higher Vocational Normal School as an Example
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作者 Meiping Huang 《Journal of Contemporary Educational Research》 2024年第2期123-130,共8页
In the era of digital empowerment,the digital reform of higher vocational courses has become an inevitable trend.To explore professional curriculum reform,this study takes the“Class Management”course in the primary ... In the era of digital empowerment,the digital reform of higher vocational courses has become an inevitable trend.To explore professional curriculum reform,this study takes the“Class Management”course in the primary education major of higher vocational teachers as the research object,analyzes the importance of digital empowerment to curriculum reform,and discusses the teaching of the“Class Management”course new model and content reform plan.Digital technology empowering traditional courses is a new trend,which is both an opportunity and a challenge.This study aims to explore the application of digital technology in courses and provide certain guidelines for curriculum reform in the field of education. 展开更多
关键词 Digital empowerment Curriculum reform Innovative exploration
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Analysis of coastline changes and influencing factors for the Macao Special Administrative Region based on Neural Network Algorithms
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作者 Xiaofang Jiang Feijian Yin 《Acta Oceanologica Sinica》 CSCD 2024年第11期118-130,共13页
The Macao Special Administrative Region is located in the southeastern coastal area of China.The region of Macao was narrow in the history,so land reclamation has become a main means of expanding its geographical scop... The Macao Special Administrative Region is located in the southeastern coastal area of China.The region of Macao was narrow in the history,so land reclamation has become a main means of expanding its geographical scope.Exploring the significance of land reclamation for the planning and urban construction of the Macao region provides valuable references.(1)The Google Earth Engine(GEE)cloud processing platform is used in this study to calculate the modified normalized difference water index(MNDWI)based on Landsat data from 1986 to 2021;(2)the Jenks natural index classification method is used to extract the water body range,and the water body boundary as well as area at different periods is calculated combined with the neural network classification method in the environment for visualizing images(ENVI)software;(3)this study then combines the patch-generating land use simulation(PLUS)model to predict the future trend of shoreline changes in the study area in 2036.The result indicates that the MNDWI and neural net classification method lead to a high classification accuracy with both the overall accuracy(OA)and Kappa coefficient being higher than 87%.Land reclamation activities in Macao were gradually intense from 1986 to 2021,with social and economic conditions such as transportation being main influencing factors,which provides valuable references and inspiration for the regional planning of the Macao Special Administrative Region. 展开更多
关键词 Macao Special administrative Region Google Earth Engine reclamation of land from the sea water body index water boundary
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Research on Interdisciplinary Project-Based Teaching in Primary Schools Catalyzed by Digital Intelligence Empowerment
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作者 Huihui Wei 《Journal of Contemporary Educational Research》 2024年第7期304-309,共6页
With the rapid development of information technology,digital intelligence empowerment has gradually become an important direction of educational innovation.This paper uses the case analysis method to explore in depth ... With the rapid development of information technology,digital intelligence empowerment has gradually become an important direction of educational innovation.This paper uses the case analysis method to explore in depth how digital intelligence empowerment and project-based teaching can promote the integration of primary school curricula.Taking the teaching of intelligent patrol cars as an example,this paper analyses the positive role of digital intelligence empowerment in improving teaching effectiveness and cultivating students’comprehensive ability.The research results show that digital intelligence empowerment not only enriches teaching resources but also optimizes the teaching process.Combined with project-based teaching methods,it can effectively improve students’interest in learning and performance.This study provides a useful reference and inspiration for the project-based teaching of curriculum integration in primary schools and has certain practical significance and theoretical value for promoting the process of educational informatization. 展开更多
关键词 Digital intelligence empowerment Curriculum integration PROJECT-BASED Intelligent patrol car
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Empowerment in chronic wound care——exploring the scope for patient contribution
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作者 Benedikt Hackert Ewa Klara Stürmer Ulrich Weger 《Frontiers of Nursing》 2024年第1期1-16,共16页
Objective:In this study,we investigated the concept of empowerment in chronic wound care and propose to facilitate patient control by making use of degrees of freedom(DOF):that is,shaping of everyday wound care tasks ... Objective:In this study,we investigated the concept of empowerment in chronic wound care and propose to facilitate patient control by making use of degrees of freedom(DOF):that is,shaping of everyday wound care tasks initiated by patients and based on their wishes,mostly in terms of patients executing treatment steps,requesting or directing health care professionals to under take changes,or modifications of internal states.Methods:As a first step,we conducted a systematic literature search,followed by an inductive form of qualitative content analysis,which resulted in the identification of 5 dimensions as main elements of empowerment:education and shared decision making,adherence to self-care behaviors,responsibility and control,general call for empowerment,and DOF.However,the latter are noticeably absent in the literature.To investigate patients'freedom in shaping the wound care process,we conducted a second literature search.Results:A number of possibilities for patients to influence the wound care process could be identified,but experimental or clinical evidence about their effects is missing,their variety is limited,and they are only inadequately described.Conclusions:However,DOF should be an indispensable aspect of genuine empowerment,since they allow patients to occupy the role of the agent in the treatment process and give rise to the subjective experience of feeling empowered.Thus,in the third part,we develop a research proposal on how to investigate and include DOF in the clinical practice of wound care.Finally,limitations about implementations are discussed(e.g.,patients being reluctant to overcome their passive role,resulting in frustration for health care professionals). 展开更多
关键词 ADHERENCE chronic wounds control degrees of freedom empowerment shared decision making
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The Impact of Bundled Nursing Interventions Based on Empowerment Theory on Patients with Indwelling Urinary Catheters
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作者 Yongna Qu 《Journal of Clinical and Nursing Research》 2024年第11期49-54,共6页
Objective:To explore the value of bundled nursing interventions based on empowerment theory in the care of patients with indwelling urinary catheters.Methods:Forty-two patients with indwelling urinary catheters,admitt... Objective:To explore the value of bundled nursing interventions based on empowerment theory in the care of patients with indwelling urinary catheters.Methods:Forty-two patients with indwelling urinary catheters,admitted from June 2022 to June 2023,were sampled and randomly divided using a random number table.Group A received bundled nursing care based on empowerment theory,while Group B received standard care.The differences in catheterization duration,unplanned extubation rate,emotional scores,quality of life scores,and adverse events were compared.Results:Group A had a shorter catheterization duration and a lower rate of unplanned extubation than Group B,with P<0.05.Anxiety(SAS)and depression(SDS)scores were lower in Group A than in Group B,with P<0.05,and the quality of life(SF-36)scores were higher in Group A than in Group B,with P<0.05.The adverse event rate for Group A was also lower than that for Group B,with P<0.05.Conclusion:Patients with indwelling urinary catheters who received bundled nursing care based on empowerment theory experienced improved emotional stability,optimized quality of life,fewer unplanned extubation events,and the intervention was highly effective and feasible. 展开更多
关键词 Indwelling urinary catheter patients Bundled nursing empowerment theory Impact
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Problems and Countermeasures in the Training of Master of Translation and Interpreting Talents in the Context of Technological Empowerment
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作者 Tangxikun He 《Journal of Contemporary Educational Research》 2024年第8期76-87,共12页
This paper aims to explore the problems and countermeasures in the training of Master of Translation and Interpreting(MTI)talents in the context of technological empowerment.Through methods such as questionnaires and ... This paper aims to explore the problems and countermeasures in the training of Master of Translation and Interpreting(MTI)talents in the context of technological empowerment.Through methods such as questionnaires and literature review,the study analyzes the problems in the training of MTI talents under technological empowerment and,by examining the feasibility and applicability of technologies,proposes countermeasures to these problems.The research finds that there are still problems in four areas:training concept,teaching content,research in the current training of MTI talents,and mutual empowerment of technology and education.Four countermeasures are suggested to address these problems,including utilizing technology to promote personalized training and optimize teaching content.This study provides valuable references for future educators to leverage technology in the training of MTI talents. 展开更多
关键词 PROBLEM COUNTERMEASURE Talent training Master of Translation and Interpreting Technological empowerment
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Empowerment of Precise Ideological and Political Education in Higher Education with Educational Digitalization
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作者 Yan Dong Yu Yu Ge Yao 《Journal of Contemporary Educational Research》 2024年第4期23-28,共6页
The study explores how educational digitalization enables the precise development of ideological and political education in colleges and universities.Digital transformation enables colleges and universities to accurat... The study explores how educational digitalization enables the precise development of ideological and political education in colleges and universities.Digital transformation enables colleges and universities to accurately define educational objectives,content strategies,effect evaluation,and process management,and realize the precision and intelligence of ideological and political education.The application of big data technology enhances the data-oriented thinking of teachers and students,promotes the accurate application of data,and improves the efficiency of ideological and political education.The research also prospected a new vision of the digital construction of ideological and political courses and clarified the theoretical and practical path of the implementation and evaluation mode of ideological and political courses under digital empowerment.Education digitalization enables precise ideological and political education,which is a key way to promote the innovative development of ideological and political education in colleges and universities and will strongly support the improvement of the overall quality of higher education and the training of excellent talents. 展开更多
关键词 Education digital empowerment Precise ideological and political education Improvement of efficiency
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Exploring Cyber Threat Intelligence into Land Administration Systems for Enhanced Cyber Resilience
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作者 Pierre-François Blin Trias Aditya +1 位作者 Purnama Budi Santosa Christophe Claramunt 《Journal of Geographic Information System》 2025年第1期45-65,共21页
The current global cybersecurity landscape, characterized by the increasing scale and sophistication of cyberattacks, underscores the importance of integrating Cyber Threat Intelligence (CTI) into Land Administration ... The current global cybersecurity landscape, characterized by the increasing scale and sophistication of cyberattacks, underscores the importance of integrating Cyber Threat Intelligence (CTI) into Land Administration Systems (LAS). LAS services involve requests and responses concerning public and private cadastral data, including credentials of parties, ownership, and spatial parcels. This study explores the integration of CTI in LAS to enhance cyber resilience, focusing on the unique vulnerabilities of LAS, such as sensitive data management and interconnection with other critical systems related to spatial data uses and changes. The approach employs a case study of a typical country-specific LAS to analyse structured vulnerabilities and their attributes to determine the degree of vulnerability of LAS through a quantitative inductive approach. The analysis results indicate significant improvements in identifying and mitigating potential threats through CTI integration, thus enhancing cyber resilience. These findings are crucial for policymakers and practitioners to develop robust cybersecurity strategies for LAS. 展开更多
关键词 Cyber Threat Intelligence Common Vulnerabilities and Exposures Geodata Land administration Systems Risk Assessment Spatial Cadastral Data
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AI-Driven Governance:Enhancing Transparency and Accountability in Public Administration
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作者 Changkui LI 《数字社会与虚拟治理》 2025年第1期1-16,共16页
Artificial Intelligence(AI)is transforming public administration by improving efficiency,en-hancing transparency,and facilitating data-driven decision-making.This paper explores the integration of AI in government dec... Artificial Intelligence(AI)is transforming public administration by improving efficiency,en-hancing transparency,and facilitating data-driven decision-making.This paper explores the integration of AI in government decision-making,examining its applications,challenges,and policy recommendations.The study highlights the role of AI in policy analysis,admin-istrative efficiency,financial management,and public participation.Key challenges such as algorithmic bias,data privacy concerns,explainability issues,and regulatory gaps are dis-cussed.The paper proposes a set of policy recommendations,including the establishment of AI ethics councils,implementation of explainability standards,enhancement of public AI literacy,and the creation of AI transparency laws.Future research should focus on hybrid human-machine governance models to ensure AI adoption aligns with democratic principles and accountability standards.Ultimately,responsible AI implementation can democratize governance,increase public trust,and lead to more effective and transparent public adminis-tration. 展开更多
关键词 Artificial Intelligence Public administration TRANSPARENCY ACCOUNTABILITY AI ETHICS
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Intranasal iron administration induces iron deposition,immunoactivation,and cell-specific vulnerability in the olfactory bulb of C57BL/6 mice
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作者 Xiao-Qing Mi Bao-Chen Liu +6 位作者 Le Qu Yu Yuan Hui Li Ao-Yang Xu Yu-Lin Zhang Jun-Xia Xie Ning Song 《Zoological Research》 2025年第1期209-224,共16页
Iron is the most abundant transition metal in the brain and is essential for brain development and neuronal function;however,its abnormal accumulation is also implicated in various neurological disorders.The olfactory... Iron is the most abundant transition metal in the brain and is essential for brain development and neuronal function;however,its abnormal accumulation is also implicated in various neurological disorders.The olfactory bulb(OB),an early target in neurodegenerative diseases,acts as a gateway for environmental toxins and contains diverse neuronal populations with distinct roles.This study explored the cell-specific vulnerability to iron in the OB using a mouse model of intranasal administration of ferric ammonium citrate(FAC).Olfactory function was assessed through olfactory discrimination tests,while iron levels in OB tissues,cerebrospinal fluid(CSF),and serum were quantified using inductively coupled plasma mass spectrometry(ICP-MS),immunohistochemical staining,and iron assays.Transcriptomic changes and immune responses were assessed using RNA sequencing and immune cell infiltration analysis.Results showed that intranasal FAC administration impaired olfactory function,accompanied by iron deposition in the olfactory mucosa and OB,as well as damage to olfactory sensory neurons.Notably,these effects occurred without elevations in CSF or serum iron levels.OB iron accumulation activated multiple immune cells,including microglia and astrocytes,but did not trigger ferroptosis.Spatial transcriptomic sequencing of healthy adult mouse OBs revealed significant cellular heterogeneity,with an abundance of neuroglia and neurons.Among neurons,GABAergic neurons were the most prevalent,followed by glutamatergic and dopaminergic neurons,while cholinergic and serotonergic neurons were sparsely distributed.Under iron-stressed conditions,oligodendrocytes,dopaminergic neurons,and glutamatergic neurons exhibited significant damage,while GABAergic neurons remained unaffected.These findings highlight the selective vulnerability of neuronal and glial populations to iron-induced stress,offering novel insights into the loss of specific cell types in the OB during iron dysregulation. 展开更多
关键词 Intranasal administration Olfactory bulb IRON Ferroptosis Immune response
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L-arginine administration exacerbates myocardial injury in diabetics via prooxidant and proinflammatory mechanisms along with myocardial structural disruption
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作者 Rasha A Mansouri Esam M Aboubakr +1 位作者 Huda F Alshaibi Adel M Ahmed 《World Journal of Diabetes》 2025年第2期197-215,共19页
BACKGROUND L-arginine(L-Arg)is one of the most widely used amino acids in dietary and pharmacological products.However,the evidence on its usefulness and dose limitations,especially in diabetics is still controversial... BACKGROUND L-arginine(L-Arg)is one of the most widely used amino acids in dietary and pharmacological products.However,the evidence on its usefulness and dose limitations,especially in diabetics is still controversial.AIM To investigate the effects of chronic administration of different doses of L-Arg on the cardiac muscle of type 2 diabetic rats.METHODS Of 96 male rats were divided into 8 groups as follows(n=12):Control,0.5 g/kg L-Arg,1 g/kg L-Arg,1.5 g/kg L-Arg,diabetic,diabetic+0.5 g/kg L-Arg,diabetic+1 g/kg L-Arg,and diabetic+1.5 g/kg L-Arg;whereas L-Arg was orally administered for 3 months to all treated groups.RESULTS L-Arg produced a moderate upregulation of blood glucose levels to normal rats,but when given to diabetics a significant upregulation was observed,associated with increased nitric oxide,inflammatory cytokines,and malonaldehyde levels in diabetic rats treated with 1 g/kg L-Arg and 1.5 g/kg L-Arg.A substantial decrease in the antioxidant capacity,superoxide dismutase,catalase,glutathione peroxidase,reduced glutathione concentrations,and Nrf-2 tissue depletion were observed at 1 g/kg and 1.5 g/kg L-Arg diabetic treated groups,associated with myocardial injury,fibrosis,α-smooth muscle actin upregulation,and disruption of desmin cardiac myofilaments,and these effects were not noticeable at normal treated groups.On the other hand,L-Arg could significantly improve the lipid profile of diabetic rats and decrease their body weights.CONCLUSION L-Arg dose of 1 g/kg or more can exacerbates the diabetes injurious effects on the myocardium,while 0.5 g/kg dose can improve the lipid profile and decrease the body weight. 展开更多
关键词 L-arginine administration Type 2 diabetes Cardiac muscle injury Oxidative stress Inflammatory cytokines Desmin disruption
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走向重塑权能:empowerment含义的反思性诠释 被引量:2
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作者 彭宗峰 《天府新论》 CSSCI 2022年第2期98-106,共9页
Empowerment是源于西方社会工作学的概念。基于对追求标的物的不同理解,国内形成了关于empowerment的三种视角,即能力视角、权利视角和权力视角。这三个视角虽然相互分化,但却并不相互断裂,而是在领域、关系和主体等方面具有一定的联结... Empowerment是源于西方社会工作学的概念。基于对追求标的物的不同理解,国内形成了关于empowerment的三种视角,即能力视角、权利视角和权力视角。这三个视角虽然相互分化,但却并不相互断裂,而是在领域、关系和主体等方面具有一定的联结性。从更深一层次看,empowerment中的能力、权利和权力是相互转化的,内含着权能辩证法。从统合角度看,empowerment其实是一个历史性的总体性概念,本质上是在社会转型的情境中,聚焦相对弱势者的发展问题,并通过建立在潜能本体基础之上的能力、权利和权力之间的权能辩证法,推动实现更加均衡、更加公平发展的过程。在此意义上,empowerment可以被理解为重塑权能。 展开更多
关键词 empowerment 能力 权利 权力 重塑权能
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Diabetes empowerment scores among type 2 diabetes mellitus patients and its correlated factors: A cross-sectional study in a primary care setting in Malaysia 被引量:4
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作者 Thew Hui Zhu Ching Siew Mooi +1 位作者 Nurainul Hana Shamsuddin Ching Siew Mooi 《World Journal of Diabetes》 SCIE CAS 2019年第7期403-413,共11页
BACKGROUND There are limited studies on diabetes empowerment among type 2 diabetes patients,particularly in the primary care setting.AIM To assess the diabetes empowerment scores and its correlated factors among type ... BACKGROUND There are limited studies on diabetes empowerment among type 2 diabetes patients,particularly in the primary care setting.AIM To assess the diabetes empowerment scores and its correlated factors among type 2 diabetes patients in a primary care clinic in Malaysia.METHODS This is a cross sectional study involving 322 patients with type 2 diabetes mellitus(DM)followed up in a primary care clinic.Systematic sampling method was used for patient recruitment.The Diabetes Empowerment Scale(DES)questionnaire was used to measure patient empowerment.It consists of three domains:(1)Managing the psychosocial aspect of diabetes(9 items);(2)Assessing dissatisfaction and readiness to change(9 items);and(3)Setting and achieving diabetes goal(10 items).A score was considered high if it ranged from 100 to 140.Data analysis was performed using SPSS version 25 and multiple linear regressions was used to identify the predictors of total diabetes empowerment scores.RESULTS The median age of the study population was 55 years old.56%were male and the mean duration of diabetes was 4 years.The total median score of the DES was 110[interquartile range(IQR)=10].The median scores of the three subscales were 40 with(IQR=4)for"Managing the psychosocial aspect of diabetes";36 with(IQR=3)for"Assessing dissatisfaction and readiness to change";and 34 with(IQR=5)for"Setting and achieving diabetes goal".According to multiple linear regressions,factors that had significant correlation with higher empowerment scores among type 2 diabetes patients included an above secondary education level(P<0.001),diabetes education exposure(P=0.003),lack of ischemic heart disease(P=0.017),and lower glycated hemoglobin(HbA1c)levels(P<0.001).CONCLUSION Diabetes empowerment scores were high among type 2 diabetes patients in this study population.Predictors for high empowerment scores included above secondary education level,diabetes education exposure,lack of ischemic heart disease status and lower HbA1c. 展开更多
关键词 DIABETES empowerment SCORES DIABETES empowerment Scale Type 2 DIABETES Primary care MALAYSIA
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