High-power laser technology is widely used in manufacturing processing,medical diagnosis,and treatment,and is one of the important fields of strategic high-tech competition in China at the moment.In the context of ind...High-power laser technology is widely used in manufacturing processing,medical diagnosis,and treatment,and is one of the important fields of strategic high-tech competition in China at the moment.In the context of industrial upgrading,high-power laser technology plays an important role in leading the development of the manufacturing industry and industrial intelligence.Based on this,this paper carries out research on high-power laser technology and industry,summarizes the basic principle and classification of high-power laser technology,analyzes the current status of high-power laser technology industry,points out the opportunities and challenges faced by the industry development,puts forward suggestions to promote the development of high-power laser technology industry,and to provide an effective reference for the application and development of high-power laser technology.展开更多
Some aspects of the robot application in the iron and steel industry were introduced.Even though many successful robot systems improved automation and human-machine operation in iron plants,based on the characteristic...Some aspects of the robot application in the iron and steel industry were introduced.Even though many successful robot systems improved automation and human-machine operation in iron plants,based on the characteristics of the iron and steel industry,difficulties remain for robot applications that are different from other industries.Research and development for robot application is necessary to promote more robots that help personnel work.Furthermore,some key points,new applications,and technological innovation need to be focused on.展开更多
Targeting modernization, we should keep to the Chinese-style path of car- rying out industrialization in a new way and advancing IT application, urbanization, and agricultural modernization. In the research, the scien...Targeting modernization, we should keep to the Chinese-style path of car- rying out industrialization in a new way and advancing IT application, urbanization, and agricultural modernization. In the research, the scientific concepts of IT applica- tion, urbanization, agricultural modernization and industrialization were illustrated and the interrelations were analyzed, with measures on harmonized development pro- posed based on existing problems.展开更多
This paper makes an in-depth study of the status quo and trend of the development of the big health industry under the background of digitalization,aiming to explore ways to promote the transformation,upgrading and su...This paper makes an in-depth study of the status quo and trend of the development of the big health industry under the background of digitalization,aiming to explore ways to promote the transformation,upgrading and sustainable development of the big health industry through technological innovation and policy guidance,and provide valuable references for the government,enterprises and universities and other stakeholders to promote the high-quality development of the big health industry in the digital era.展开更多
This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and pract...This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and practical applications across a broad range of industries,including biotechnology,automotive,aerospace,and telecom-munications.By examining critical advancements in AI algorithms,machine learning,deep learning models,simulations,and predictive analytics,the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies.The review integrates both qualitative and quantitative data derived from academic studies,industry reports,and real-world case studies to showcase the tangible impacts of AI on product innovation,process optimization,and strategic decision-making.Notably,it discusses the challenges of integrating AI within complex industrial systems,such as ethical concerns,technical limitations,and the need for regulatory oversight.The findings reveal a mixed landscape where AI has significantly accelerated R&D processes,reduced costs,and enabled more precise simulations and predictions,but also highlighted gaps in knowledge transfer,skills adaptation,and cross-industry standardization.By bridging the gap between AI theory and practice,the review offers insights into the effectiveness,successes,and obstacles faced by organizations as they implement AI-driven solutions.Concluding with a forward-looking perspective,the review identifies emerging trends,future challenges,and promising opportunities inAI-poweredR&D,such as the rise of autonomous systems,AI-driven drug discovery,and sustainable energy solutions.It offers a holistic understanding of how AI is shaping the future of technological innovation and provides actionable insights for researchers,engineers,and policymakers involved in high-tech Research and Development(R&D).展开更多
The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic r...The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic research, and Draba nemerosa Hebecarpa jujube diarrhoea lung soup is mostly used in the form of “Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup with additional subtractions or other formulas combining Draba nemerosa Hebecarpa Hebecarpa Hebecarpa jujube diarrhoea lung soup” in the clinical application. This article will focus on the main mechanisms of Draba nemerosa Hebecarpa jujube diarrhoea lung soup and its main components in the treatment of respiratory and circulatory diseases, and will give a review of the basic research on Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup as follows.展开更多
Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July...Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July 2022 to May 2023 were randomly divided into two groups,32 cases in the control group and 32 cases in the intervention group.The control group was given conventional teaching methods,and the intervention group was given the bedside rhetorical teaching method on the basis of the conventional teaching.The differences in the methods of teaching between the two groups were compared after the end of the internship,and there was a statistically significant difference with P<0.05.Results:The scores of the interns in the intervention group were significantly better than those of the control group in theoretical knowledge,communication skills,and case analysis items(P<0.05).Conclusion:The bedside rhetorical teaching method transforms classroom education into bedside teaching,which enables the interns to apply the theoretical knowledge to clinical practice,and has a higher improvement in the three aspects of disease knowledge,communication skills,and case analysis,cultivates the interns’comprehensive clinical skills,and lays a good foundation for the future entry into the nursing field.展开更多
With the acceleration of economic development and globalization and the rapid development of China’s foreign economy,the position of English education in higher vocational education has become increasingly prominent....With the acceleration of economic development and globalization and the rapid development of China’s foreign economy,the position of English education in higher vocational education has become increasingly prominent.Particularly in the multi-ethnic and multi-cultural areas of Guangxi Zhuang Autonomous Region,higher vocational education undertakes the responsibility of talent export for the construction of the China-ASEAN foreign trade exchange platform.However,the current phenomena and problems existing in higher vocational English education in Guangxi need to be deeply discussed and solved.Therefore,this paper discusses the development ideas of English education mode in Guangxi higher vocational education and studies the feasibility suggestions,in order to provide a reference for the future development of higher vocational English education in Guangxi.展开更多
Microbial flocculant （MBF） is a kind of novel flocculant, which is widely used for the food industry, highly concentrated organic waste water treatment and the urban water supply technology. Due to its characteristi...Microbial flocculant （MBF） is a kind of novel flocculant, which is widely used for the food industry, highly concentrated organic waste water treatment and the urban water supply technology. Due to its characteristics of superior flocculation effect, without secondary pollution to the environment and being easily degraded, MBF has been emerging as a hotspot of water treatment research in recent years. In this paper, the latest progress of the preparation of MBFs and the flocculating mechanism were presented. The practical application research of MBFs for water treatment was reviewed. Finally, suggestions and development prospect of research on MBFs were discussed.展开更多
Due to the restrictions on the conditions for afforestation and sand control,the development research,and application of sand barriers have accelerated in recent years,but some problems that cannot be ignored have eme...Due to the restrictions on the conditions for afforestation and sand control,the development research,and application of sand barriers have accelerated in recent years,but some problems that cannot be ignored have emerged in practice. In this paper,the functions of wind prevention,sand blocking and fixation,improving soil physical and chemical properties and increasing plant diversity of sand barriers,accretion coefficient and capacity between sand barriers,and mobile sand barriers were analyzed firstly,and then several issues that should be noted in the development and application of sand barriers were proposed. The results show that sand barriers can fix sand on the spot and maintain the stability of sand surface. As an auxiliary measure before afforestation on a mobile sand surface,they are practical and feasible. The biggest drawback of sand barriers is that they are easy to be saturated. Although they can increase plant diversity and surface roughness,they lose the function of blocking sand flow after being saturated,and their function of in-situ sand fixation also rapidly decreases with the degradation of sand barriers. Mobile sand barriers overcome the disadvantage of sand barriers being easy to be saturated to some extent,but the cost greatly increases. In terms of desertification prevention and control by plants,plants are used as sand barriers to study their functions of sand blocking and sand fixation in many researches and practices,but the more important ecological functions of adjusting temperature on sand surface and achieving surface thermodynamic equilibrium of plants are ignored.展开更多
The light weight heat treated B-grade bulletproof steel was developed through composition design and optimization based on multiplex alloying,multiplex micro-alloying design ideas and complex phase structure strengthe...The light weight heat treated B-grade bulletproof steel was developed through composition design and optimization based on multiplex alloying,multiplex micro-alloying design ideas and complex phase structure strengthening theory.The puzzle how to avoid the quenching deformation problem of super high strength thin sheet was solved through heat treatment in a die with a set of cooling system.Such B-grade bulletproof steel plate has fine tempered lath martensite structure.The shooting and certification test results showed that the shoot resistance of B-grade bulletproof steel plate can meet the protection demand of Protection specification for cash carrying vehicles(GA 164—2005).In comparison with B-grade bulletproof steel plate made by one of the companies in Sweden,the weight of the developed B-grade bulletproof steel plate can be decreased by 8 %under the same shoot resistance condition.It will be meaningful for cash truck and anti-hijacking vehicle to realize light weight,energy conservation and emission reduction.展开更多
There is a growing demand for customised,biocompatible,and sterilisable components in the medical busi-ness.3D Printing is a disruptive technology for healthcare and provides significant research and development avenu...There is a growing demand for customised,biocompatible,and sterilisable components in the medical busi-ness.3D Printing is a disruptive technology for healthcare and provides significant research and development avenues.Simple 3D printing service gives patients low-cost individualised prostheses,implants,and gadgets,en-abling surgeons to operate more effectively with customised equipment and models;and assisting medical device manufacturers in developing new and faster goods.3D printed tissue pieces can overcome various challenges and may eventually allow medication companies to streamline research and development.In the long run,it may also assist in lowering prices and making medicines more accessible and effective for everybody.There is a growing corpus of research on the advantages of employing 3D printed anatomic models in teaching and training.The capacity to 3D printing individual anatomical diseases for practical learning is one of the funda-mental contrasts between utilising 3D and regular anatomical models.3D printing is very appealing for producing patient-specific implants.This literature review-based paper explores the role of 3D printing and 3D bioprinting in healthcare.It briefs the need and progressive steps for implementing 3D printing in healthcare and presented various facilities and enablers of 3D printing for the healthcare sector.Finally,this paper identifies and discusses the significant applications of 3D printing for healthcare research and development.3D printing services can be deployed to easily construct complex geometries in plastic or metal with good precision.This results in improved prototypes,lower costs,and lower part processing times.They can now physically create with natural materials,previously unattainable with prior technologies.Every hospital should have 3D printers in the future,allowing new organs/parts to be developed in-house.展开更多
Objective To help investors assess and control the costs of new drug development and reduce the risks of new drug development projects.Methods Cost analysis and financial forecasting were carried out with the integrat...Objective To help investors assess and control the costs of new drug development and reduce the risks of new drug development projects.Methods Cost analysis and financial forecasting were carried out with the integrated approach of earned value management.According to the principle of earned value management deviation analysis,the basic process of the new drug research and development project was combined with the hypothesis method from the research of Tufts Drug Development Research Center.Results and Conclusion If the project progress check was carried out in the clinical trial,the project costs were found overspent,the efficiency was low,the project progress was faster,and the resource investment was ahead.It is recommended that the adjustment should be made to reduce the input of resources,and increase the efficient key personnel to take the place of some less efficient staff.展开更多
Purpose:The goal of this study is to analyze the relationship between funded and unfunded papers and their citations in both basic and applied sciences.Design/methodology/approach:A power law model analyzes the relati...Purpose:The goal of this study is to analyze the relationship between funded and unfunded papers and their citations in both basic and applied sciences.Design/methodology/approach:A power law model analyzes the relationship between research funding and citations of papers using 831,337 documents recorded in the Web of Science database.Findings:The original results reveal general characteristics of the diffusion of science in research fields:a)Funded articles receive higher citations compared to unfunded papers in journals;b)Funded articles exhibit a super-linear growth in citations,surpassing the increase seen in unfunded articles.This finding reveals a higher diffusion of scientific knowledge in funded articles.Moreover,c)funded articles in both basic and applied sciences demonstrate a similar expected change in citations,equivalent to about 1.23%,when the number of funded papers increases by 1%in journals.This result suggests,for the first time,that funding effect of scientific research is an invariant driver,irrespective of the nature of the basic or applied sciences.Originality/value:This evidence suggests empirical laws of funding for scientific citations that explain the importance of robust funding mechanisms for achieving impactful research outcomes in science and society.These findings here also highlight that funding for scientific research is a critical driving force in supporting citations and the dissemination of scientific knowledge in recorded documents in both basic and applied sciences.Practical implications:This comprehensive result provides a holistic view of the relationship between funding and citation performance in science to guide policymakers and R&D managers with science policies by directing funding to research in promoting the scientific development and higher diffusion of results for the progress of human society.展开更多
Parasitic disease is one of the most serious diseases in humans and animals. Animal antiparasitic drugs are mainly used to kill, expel and prevent animal parasites, and they are divided into anthelmintics, antiprotozo...Parasitic disease is one of the most serious diseases in humans and animals. Animal antiparasitic drugs are mainly used to kill, expel and prevent animal parasites, and they are divided into anthelmintics, antiprotozoals, insecticides, and so on. Animal antiparasitic drugs play an important role in the prevention and control of animal parasitic diseases, healthy development of animal husbandry and security of public health. In recent years, as people pay more attention paid to parasitic diseases, the research and development of antiparasitic drugs have made great progresses. Mastering the research and application progresses of antiparasitic drugs is of great significance to clinical medication and basic research. This paper reviews the history, current situation, the latest progresses and future development directions of research and application of antiparasitic drugs.展开更多
Plant virus disease is one of the major causes of biological disasters in agriculture worldwide. Given the complexity of transmission media and plant disease infection mechanisms, the prevention and control of plant v...Plant virus disease is one of the major causes of biological disasters in agriculture worldwide. Given the complexity of transmission media and plant disease infection mechanisms, the prevention and control of plant viral diseases is a great challenge, and an efficient green pesticide is urgently needed. For this reason, when developing candidate drug leads to regulate plant viruses, pesticide experts have focused on characteristics such as low pesticide resistance, eco-friendliness, and novel mechanism. Researchers have also theoretically investigated the molecular targets of viruses infecting agricultural crops. Antiviral screening models have been constructed based on these molecular targets, and the mechanisms of commercial drugs and high-activity compounds have been extensively investigated. After screening, some compounds have been applied in the field and found to have good commercial prospects; these drugs may be used to create new green antiviral pesticides to control plant viruses. This paper reviews the screening, mode of action, development and application of recently used plant-based antiviral agents.展开更多
The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as t...The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as the main development direc- tion of edible insect proteins. And we also pointed out the bottlenecks that restricted the development and utilization of proteins in edible insects, and proposed the prospect of the research, development and utilization of edible insects proteins.展开更多
In this paper, we conduct research on the development trend and general applications of the fuzzy rough granular computing theory. Granular computing is a new concept of general information processing and computing pa...In this paper, we conduct research on the development trend and general applications of the fuzzy rough granular computing theory. Granular computing is a new concept of general information processing and computing paradigm which covers all the granularity the study of the theory, methods, techniques and the tools. In many areas are the basic ideas of granular computing, such as the interval analysis, rough set theory, clustering analysis and information retrieval, machine learning, database, etc. With the theory of domain known division of target concept and rule acquisition, in knowledge discovery, data mining and the pattern recognition is widely used. Under this basis, in this paper, we propose the fuzzy rough theory based computing paradigm that gains ideal performance.展开更多
文摘High-power laser technology is widely used in manufacturing processing,medical diagnosis,and treatment,and is one of the important fields of strategic high-tech competition in China at the moment.In the context of industrial upgrading,high-power laser technology plays an important role in leading the development of the manufacturing industry and industrial intelligence.Based on this,this paper carries out research on high-power laser technology and industry,summarizes the basic principle and classification of high-power laser technology,analyzes the current status of high-power laser technology industry,points out the opportunities and challenges faced by the industry development,puts forward suggestions to promote the development of high-power laser technology industry,and to provide an effective reference for the application and development of high-power laser technology.
文摘Some aspects of the robot application in the iron and steel industry were introduced.Even though many successful robot systems improved automation and human-machine operation in iron plants,based on the characteristics of the iron and steel industry,difficulties remain for robot applications that are different from other industries.Research and development for robot application is necessary to promote more robots that help personnel work.Furthermore,some key points,new applications,and technological innovation need to be focused on.
文摘Targeting modernization, we should keep to the Chinese-style path of car- rying out industrialization in a new way and advancing IT application, urbanization, and agricultural modernization. In the research, the scientific concepts of IT applica- tion, urbanization, agricultural modernization and industrialization were illustrated and the interrelations were analyzed, with measures on harmonized development pro- posed based on existing problems.
文摘This paper makes an in-depth study of the status quo and trend of the development of the big health industry under the background of digitalization,aiming to explore ways to promote the transformation,upgrading and sustainable development of the big health industry through technological innovation and policy guidance,and provide valuable references for the government,enterprises and universities and other stakeholders to promote the high-quality development of the big health industry in the digital era.
文摘This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and practical applications across a broad range of industries,including biotechnology,automotive,aerospace,and telecom-munications.By examining critical advancements in AI algorithms,machine learning,deep learning models,simulations,and predictive analytics,the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies.The review integrates both qualitative and quantitative data derived from academic studies,industry reports,and real-world case studies to showcase the tangible impacts of AI on product innovation,process optimization,and strategic decision-making.Notably,it discusses the challenges of integrating AI within complex industrial systems,such as ethical concerns,technical limitations,and the need for regulatory oversight.The findings reveal a mixed landscape where AI has significantly accelerated R&D processes,reduced costs,and enabled more precise simulations and predictions,but also highlighted gaps in knowledge transfer,skills adaptation,and cross-industry standardization.By bridging the gap between AI theory and practice,the review offers insights into the effectiveness,successes,and obstacles faced by organizations as they implement AI-driven solutions.Concluding with a forward-looking perspective,the review identifies emerging trends,future challenges,and promising opportunities inAI-poweredR&D,such as the rise of autonomous systems,AI-driven drug discovery,and sustainable energy solutions.It offers a holistic understanding of how AI is shaping the future of technological innovation and provides actionable insights for researchers,engineers,and policymakers involved in high-tech Research and Development(R&D).
文摘The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic research, and Draba nemerosa Hebecarpa jujube diarrhoea lung soup is mostly used in the form of “Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup with additional subtractions or other formulas combining Draba nemerosa Hebecarpa Hebecarpa Hebecarpa jujube diarrhoea lung soup” in the clinical application. This article will focus on the main mechanisms of Draba nemerosa Hebecarpa jujube diarrhoea lung soup and its main components in the treatment of respiratory and circulatory diseases, and will give a review of the basic research on Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup as follows.
文摘Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July 2022 to May 2023 were randomly divided into two groups,32 cases in the control group and 32 cases in the intervention group.The control group was given conventional teaching methods,and the intervention group was given the bedside rhetorical teaching method on the basis of the conventional teaching.The differences in the methods of teaching between the two groups were compared after the end of the internship,and there was a statistically significant difference with P<0.05.Results:The scores of the interns in the intervention group were significantly better than those of the control group in theoretical knowledge,communication skills,and case analysis items(P<0.05).Conclusion:The bedside rhetorical teaching method transforms classroom education into bedside teaching,which enables the interns to apply the theoretical knowledge to clinical practice,and has a higher improvement in the three aspects of disease knowledge,communication skills,and case analysis,cultivates the interns’comprehensive clinical skills,and lays a good foundation for the future entry into the nursing field.
基金2022 Guangxi Education Science Planning Project“The Inheritance and Discussion of National Culture in the Internationalization of Higher Vocational Education under the Background of the New Era”(2022ZJY3095)。
文摘With the acceleration of economic development and globalization and the rapid development of China’s foreign economy,the position of English education in higher vocational education has become increasingly prominent.Particularly in the multi-ethnic and multi-cultural areas of Guangxi Zhuang Autonomous Region,higher vocational education undertakes the responsibility of talent export for the construction of the China-ASEAN foreign trade exchange platform.However,the current phenomena and problems existing in higher vocational English education in Guangxi need to be deeply discussed and solved.Therefore,this paper discusses the development ideas of English education mode in Guangxi higher vocational education and studies the feasibility suggestions,in order to provide a reference for the future development of higher vocational English education in Guangxi.
文摘Microbial flocculant （MBF） is a kind of novel flocculant, which is widely used for the food industry, highly concentrated organic waste water treatment and the urban water supply technology. Due to its characteristics of superior flocculation effect, without secondary pollution to the environment and being easily degraded, MBF has been emerging as a hotspot of water treatment research in recent years. In this paper, the latest progress of the preparation of MBFs and the flocculating mechanism were presented. The practical application research of MBFs for water treatment was reviewed. Finally, suggestions and development prospect of research on MBFs were discussed.
基金Supported by National Natural Science Foundation of China(41671528)
文摘Due to the restrictions on the conditions for afforestation and sand control,the development research,and application of sand barriers have accelerated in recent years,but some problems that cannot be ignored have emerged in practice. In this paper,the functions of wind prevention,sand blocking and fixation,improving soil physical and chemical properties and increasing plant diversity of sand barriers,accretion coefficient and capacity between sand barriers,and mobile sand barriers were analyzed firstly,and then several issues that should be noted in the development and application of sand barriers were proposed. The results show that sand barriers can fix sand on the spot and maintain the stability of sand surface. As an auxiliary measure before afforestation on a mobile sand surface,they are practical and feasible. The biggest drawback of sand barriers is that they are easy to be saturated. Although they can increase plant diversity and surface roughness,they lose the function of blocking sand flow after being saturated,and their function of in-situ sand fixation also rapidly decreases with the degradation of sand barriers. Mobile sand barriers overcome the disadvantage of sand barriers being easy to be saturated to some extent,but the cost greatly increases. In terms of desertification prevention and control by plants,plants are used as sand barriers to study their functions of sand blocking and sand fixation in many researches and practices,but the more important ecological functions of adjusting temperature on sand surface and achieving surface thermodynamic equilibrium of plants are ignored.
文摘The light weight heat treated B-grade bulletproof steel was developed through composition design and optimization based on multiplex alloying,multiplex micro-alloying design ideas and complex phase structure strengthening theory.The puzzle how to avoid the quenching deformation problem of super high strength thin sheet was solved through heat treatment in a die with a set of cooling system.Such B-grade bulletproof steel plate has fine tempered lath martensite structure.The shooting and certification test results showed that the shoot resistance of B-grade bulletproof steel plate can meet the protection demand of Protection specification for cash carrying vehicles(GA 164—2005).In comparison with B-grade bulletproof steel plate made by one of the companies in Sweden,the weight of the developed B-grade bulletproof steel plate can be decreased by 8 %under the same shoot resistance condition.It will be meaningful for cash truck and anti-hijacking vehicle to realize light weight,energy conservation and emission reduction.
文摘There is a growing demand for customised,biocompatible,and sterilisable components in the medical busi-ness.3D Printing is a disruptive technology for healthcare and provides significant research and development avenues.Simple 3D printing service gives patients low-cost individualised prostheses,implants,and gadgets,en-abling surgeons to operate more effectively with customised equipment and models;and assisting medical device manufacturers in developing new and faster goods.3D printed tissue pieces can overcome various challenges and may eventually allow medication companies to streamline research and development.In the long run,it may also assist in lowering prices and making medicines more accessible and effective for everybody.There is a growing corpus of research on the advantages of employing 3D printed anatomic models in teaching and training.The capacity to 3D printing individual anatomical diseases for practical learning is one of the funda-mental contrasts between utilising 3D and regular anatomical models.3D printing is very appealing for producing patient-specific implants.This literature review-based paper explores the role of 3D printing and 3D bioprinting in healthcare.It briefs the need and progressive steps for implementing 3D printing in healthcare and presented various facilities and enablers of 3D printing for the healthcare sector.Finally,this paper identifies and discusses the significant applications of 3D printing for healthcare research and development.3D printing services can be deployed to easily construct complex geometries in plastic or metal with good precision.This results in improved prototypes,lower costs,and lower part processing times.They can now physically create with natural materials,previously unattainable with prior technologies.Every hospital should have 3D printers in the future,allowing new organs/parts to be developed in-house.
文摘Objective To help investors assess and control the costs of new drug development and reduce the risks of new drug development projects.Methods Cost analysis and financial forecasting were carried out with the integrated approach of earned value management.According to the principle of earned value management deviation analysis,the basic process of the new drug research and development project was combined with the hypothesis method from the research of Tufts Drug Development Research Center.Results and Conclusion If the project progress check was carried out in the clinical trial,the project costs were found overspent,the efficiency was low,the project progress was faster,and the resource investment was ahead.It is recommended that the adjustment should be made to reduce the input of resources,and increase the efficient key personnel to take the place of some less efficient staff.
文摘Purpose:The goal of this study is to analyze the relationship between funded and unfunded papers and their citations in both basic and applied sciences.Design/methodology/approach:A power law model analyzes the relationship between research funding and citations of papers using 831,337 documents recorded in the Web of Science database.Findings:The original results reveal general characteristics of the diffusion of science in research fields:a)Funded articles receive higher citations compared to unfunded papers in journals;b)Funded articles exhibit a super-linear growth in citations,surpassing the increase seen in unfunded articles.This finding reveals a higher diffusion of scientific knowledge in funded articles.Moreover,c)funded articles in both basic and applied sciences demonstrate a similar expected change in citations,equivalent to about 1.23%,when the number of funded papers increases by 1%in journals.This result suggests,for the first time,that funding effect of scientific research is an invariant driver,irrespective of the nature of the basic or applied sciences.Originality/value:This evidence suggests empirical laws of funding for scientific citations that explain the importance of robust funding mechanisms for achieving impactful research outcomes in science and society.These findings here also highlight that funding for scientific research is a critical driving force in supporting citations and the dissemination of scientific knowledge in recorded documents in both basic and applied sciences.Practical implications:This comprehensive result provides a holistic view of the relationship between funding and citation performance in science to guide policymakers and R&D managers with science policies by directing funding to research in promoting the scientific development and higher diffusion of results for the progress of human society.
基金Supported by Earmarked Fund for China Agriculture Research System(CAR-38)Twelfth Five-Year National Key Technology Research and Development Program(2015BAD1101)~~
文摘Parasitic disease is one of the most serious diseases in humans and animals. Animal antiparasitic drugs are mainly used to kill, expel and prevent animal parasites, and they are divided into anthelmintics, antiprotozoals, insecticides, and so on. Animal antiparasitic drugs play an important role in the prevention and control of animal parasitic diseases, healthy development of animal husbandry and security of public health. In recent years, as people pay more attention paid to parasitic diseases, the research and development of antiparasitic drugs have made great progresses. Mastering the research and application progresses of antiparasitic drugs is of great significance to clinical medication and basic research. This paper reviews the history, current situation, the latest progresses and future development directions of research and application of antiparasitic drugs.
基金supported by the National Natural Science Foundation of China (21132003, 31460460, 21502032 and 21732002)the Subsidy Project for Outstanding Key Laboratory of Guizhou Province in China (20154004)+1 种基金the Provincial University Cooperation Plan of Guizhou Province in China (20147001)the Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan, China
文摘Plant virus disease is one of the major causes of biological disasters in agriculture worldwide. Given the complexity of transmission media and plant disease infection mechanisms, the prevention and control of plant viral diseases is a great challenge, and an efficient green pesticide is urgently needed. For this reason, when developing candidate drug leads to regulate plant viruses, pesticide experts have focused on characteristics such as low pesticide resistance, eco-friendliness, and novel mechanism. Researchers have also theoretically investigated the molecular targets of viruses infecting agricultural crops. Antiviral screening models have been constructed based on these molecular targets, and the mechanisms of commercial drugs and high-activity compounds have been extensively investigated. After screening, some compounds have been applied in the field and found to have good commercial prospects; these drugs may be used to create new green antiviral pesticides to control plant viruses. This paper reviews the screening, mode of action, development and application of recently used plant-based antiviral agents.
基金Supported by the Special Fund for Agro-scientific Research in the Public Interest(200904025)the Natural Science Foundation of Beijing(6122024)+1 种基金the Surface Project of the Science and Technology Development Program of Beijing Municipal Education Commission(KM200900005002)the Project for the Agricultural Science and Technology of Beijing(20110115)~~
文摘The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as the main development direc- tion of edible insect proteins. And we also pointed out the bottlenecks that restricted the development and utilization of proteins in edible insects, and proposed the prospect of the research, development and utilization of edible insects proteins.
文摘In this paper, we conduct research on the development trend and general applications of the fuzzy rough granular computing theory. Granular computing is a new concept of general information processing and computing paradigm which covers all the granularity the study of the theory, methods, techniques and the tools. In many areas are the basic ideas of granular computing, such as the interval analysis, rough set theory, clustering analysis and information retrieval, machine learning, database, etc. With the theory of domain known division of target concept and rule acquisition, in knowledge discovery, data mining and the pattern recognition is widely used. Under this basis, in this paper, we propose the fuzzy rough theory based computing paradigm that gains ideal performance.
