The paper concerns Cauchy,problem for one-dimensional hydromagnetic dynamics with dissipative terms. When the dissipation coefficient is equal to zero it is shown that the smooth solutions develop shocks in the finite...The paper concerns Cauchy,problem for one-dimensional hydromagnetic dynamics with dissipative terms. When the dissipation coefficient is equal to zero it is shown that the smooth solutions develop shocks in the finite time if the initial amounts of entropy and magnetic field are smaller than those of sound waves; when it is larger than zero, and the initial amounts of entropyI this dissipation coefficient and the magnetic field in each period are smaller than those of sound Waves, then the smooth solutions blow up in the finite time. Moreover, the life-span of the smooth solution is given.展开更多
In this article, we investigate the lower bound of life-span of classical solutions of the hyperbolic geometry flow equations in several space dimensions with ＂small＂ initial data. We first present some estimates on...In this article, we investigate the lower bound of life-span of classical solutions of the hyperbolic geometry flow equations in several space dimensions with ＂small＂ initial data. We first present some estimates on solutions of linear wave equations in several space variables. Then, we derive a lower bound of the life-span of the classical solutions to the equations with ＂small＂ initial data.展开更多
Dietary γ-amino butyric acid (GABA) has been suggested to decrease systolic blood pressure. This study aimed to ex-amine the effects of dietary GABA on the life span of stroke-prone spontaneously hypertensive rats (S...Dietary γ-amino butyric acid (GABA) has been suggested to decrease systolic blood pressure. This study aimed to ex-amine the effects of dietary GABA on the life span of stroke-prone spontaneously hypertensive rats (SHRSPs). In this study, life span was determined for SHRSPs provided 1% NaCl solution or 0.01% GABA in 1% NaCl solution as drinking water. The life span of the GABA-fed group (76.3 ± 1.65 days) was significantly shorter than that of the control group (81.6 ± 0.88 days). The results of this study may not be applicable to humans. Future studies will be necessary to elucidate the mechanism underlying this phenomenon.展开更多
Drosophila melanogaster mutants with deficient kynurenine (KYN) formation from tryptophan (TRP) have longer life span than wild type flies. Administration of alpha-methyl-TRP and 5-methyl-TRY, the inhibitors of TRP-KY...Drosophila melanogaster mutants with deficient kynurenine (KYN) formation from tryptophan (TRP) have longer life span than wild type flies. Administration of alpha-methyl-TRP and 5-methyl-TRY, the inhibitors of TRP-KYN metabolism, prolonged life span in wild-type flies. Both inhibitors are not available for human use. Berberine, an isoquinoline alkaloid isolated from berberis aristata is known as the herb widely used in traditional Chinese and Indian medicine. Berberin is a strong inhibitor of the enzyme catalyzing TRP conversion into KYN. Considering this particular feature we investigated the effect of berberine on life-and health-span in wild-type Drosophila melanogaster. The results of our study showed that Berberine extended mean, median and maximum life span of female flies. Berberine did not affect the number of pupae of filial generation and decreased their lethality. Berberine increased locomotor activity (vertical climbing). The results of the study suggest that berberine prolongs life- and improves health-span of Drosophila melanogaster. Berberine might be a candidate drug for prevention and treatment of aging and aging-associated medical and psychiatric disorders.展开更多
In this paper, ultrasonic （20 kHz） fatigue tests were performed on specimens of a high-strength steel in very high cycle fatigue （VHCF） regime. Experimental results showed that for most tested specimens failed in ...In this paper, ultrasonic （20 kHz） fatigue tests were performed on specimens of a high-strength steel in very high cycle fatigue （VHCF） regime. Experimental results showed that for most tested specimens failed in a VHCF regime, a fatigue crack originated from the interior of specimen with a fish-eye pattern, which contained a fine granular area （FGA） centered by an inclusion as the crack origin. Then, a two-parameter model is proposed to predict the fatigue life of high-strength steels with fish-eye mode failure in a VHCF regime, which takes into account the inclusion size and the FGA size. The model was verified by the data of present experiments and those in the literature. Furthermore, an analytic formula was obtained for estimating the equivalent crack growth rate within the FGA. The results also indicated that the stress intensity factor range at the front of the FGA varies within a small range, which is irrespective of stress amplitude and fatigue life.展开更多
The ef fects of salinity on the copepod, A cartia tonsa in terms of daily egg production rate(EPR), hatching success, fecal pellet production rate(FPR), naupliar development time and survival, sex ratio, and total lif...The ef fects of salinity on the copepod, A cartia tonsa in terms of daily egg production rate(EPR), hatching success, fecal pellet production rate(FPR), naupliar development time and survival, sex ratio, and total life span were determined in laboratory conditions through three experiments. In experiment 1, EPR, hatching success, and FPR of individual females were monitored at salinities of 13, 20, 35 and 45 during short-periods(seven consecutive days). Results show EPR was aff ected by salinity with the highest outputs recorded at 20 and 35, respectively, which were considerably higher than those at 13 and 45. Mean FPR was also higher in 35 and 20. In experiment 2, the same parameters were evaluated over total life span of females(long-term study). The best EPR and FPR were observed in 35, which was statistically higher than at 13 and 20. In experiment 3, survival rates of early nauplii until adult stage were lowest at a salinity of 13. The development time increased with increasing of salinity. Female percentage clearly decreased with increasing salinity. Higher female percentages(56.7% and 52.2%, respectively) were signifi cantly observed at two salinities of 13 and 20 compared to that at 35(25%). Total longevity of females was not af fected by salinity increment. Based on our results, for mass culture we recommend that a salinity of 35 be adopted due to higher reproductive performances, better feeding, and faster development of A. tonsa.展开更多
This paper deals with the Cauchy problem for a doubly singular parabolic equation with a weighted source ut=div｜u｜p-2um）＋｜x｜α uq ,（x,t）∈RN×（0,t）,where N ≥ 1, 1 〈 p 〈 2, m 〉 max（0,3 -p/N} satisfyi...This paper deals with the Cauchy problem for a doubly singular parabolic equation with a weighted source ut=div｜u｜p-2um）＋｜x｜α uq ,（x,t）∈RN×（0,t）,where N ≥ 1, 1 〈 p 〈 2, m 〉 max（0,3 -p/N} satisfying 2 〈 p＋m 〈 3, q 〉 1, and（α 〉 N（3 - p - m） - p. We give the secondary critical exponent on the decay asymptotic behavior of an initial value at infinity for the existence and non-existence of global solutions of the Cauchy problem. Moreover, the life span of solutions is also studied.展开更多
Owing to the complex environmental conditions, suspension could induce complicated forces on submarine pipelines and even cause vortex-induced vibration, resulting in fatigue damage of pipelines. Through aiming at the...Owing to the complex environmental conditions, suspension could induce complicated forces on submarine pipelines and even cause vortex-induced vibration, resulting in fatigue damage of pipelines. Through aiming at the 28-inch submarine pipeline in the East China Sea, the pipeline was segmented according to the similarity, considering the factors of pipe assembly, typhoon, current, wave and seabed topography. The effects of span length on natural frequency in each section of submarine pipeline were analyzed by finite element model. The maximum safe span length allowed by each pipeline section was verified by fatigue cumulative damage theory, and the fatigue life of each pipeline section were predicted. The results showed that each order natural frequency of the pipeline decreased with the increase of span length. The calculated results of empirical formulas were much smaller than those of the FEM analysis. The increase of the gap between the suspended pipeline and the seabed was beneficial to enhance the fatigue life of the suspended pipeline.展开更多
Based on the theory of continuum damage mechanics,a bi-variable damage mechanics model is developed,which,according to thermodynamics,is accessible to derivation of damage driving force,damage evolution equation and d...Based on the theory of continuum damage mechanics,a bi-variable damage mechanics model is developed,which,according to thermodynamics,is accessible to derivation of damage driving force,damage evolution equation and damage evolution criteria. Furthermore,damage evolution equations of time rate are established by the generalized Drucker＇s postulate. The damage evolution equation of cycle rate is obtained by integrating the time damage evolution equations,and the fatigue life prediction method for smooth specimens under repeated loading with constant strain amplitude is constructed. Likewise,for notched specimens under the repeated loading with constant strain amplitude,the fatigue life prediction method is obtained on the ground of the theory of conservative integral in damage mechanics. Thus,the material parameters in the damage evolution equation can be obtained by reference to the fatigue test results of standard specimens with stress concentration factor equal to 1,2 and 3.展开更多
Implications of the differences in leaf life span are still subject to debate in the field of ecophysiology.Since leaf traits associated with these differences may be decisive for determining the distribution of tree ...Implications of the differences in leaf life span are still subject to debate in the field of ecophysiology.Since leaf traits associated with these differences may be decisive for determining the distribution of tree species,this topic is particularly relevant in the context of climate change.This study analyzes the effects of the differences in leaf life span on premature losses of leaf area owing to insect herbivory and to abiotic stress.Loss of leaf area may be an important determinant of total leaf carbon assimilation.Seven Mediterranean tree species,distributed on four sites with different climates were studied.The species exhibited strong differences in leaf life span and in leaf traits,especially leaf mass per unit area.Premature leaf area losses were estimated in response to insect herbivory and summer drought over two years.The results revealed that,despite having older leaf cohorts with more damage,species with longer leaf duration had lower area lost to herbivores and less damage due to accelerated senescence during the summer drought.With respect to the predicted increase in water stress,deciduous species are at a disadvantage due to their high premature loss of leaf area and thus loss of photosynthetic capacity.展开更多
Considering the insulators ageing in a mixture of PVC and dye, set following operating conditions and time to ensure proper operation and perfect safety of industrial installations using insulated conductors. The resu...Considering the insulators ageing in a mixture of PVC and dye, set following operating conditions and time to ensure proper operation and perfect safety of industrial installations using insulated conductors. The results showed that the insulation carried out by the L.C main office was a good quality (on thermal aspect), because the resistance of the insulation is so high (i.e. 3940 Mega Ohms under normal conditions). The results showed a lifespan of 50 years at a temperature of 40°C (close to ambient temperature), plus minus 33 years at a temperature of 70°C;plus minus 22 years at a temperature of 100°C and 12 years at a temperature of 160°C. Furthermore, information on chemical attack, the results showed that PVC cables have poor resistance to sulfuric acid attack (having a pH of 1.5 and a density of 1.84 g/cm<sup>3</sup>). LC/Gecamines is able to produce locally a good quality of electrical cables.展开更多
In this paper the authors consider Cauchy problem of first order quasilinear hyperbolic and prove that existence of its periodic solutions and estimates of life span of solutions. This results reveals the relationship...In this paper the authors consider Cauchy problem of first order quasilinear hyperbolic and prove that existence of its periodic solutions and estimates of life span of solutions. This results reveals the relationship of dissipation and smoothness of periodic solutions.展开更多
The non-stationary buffeting response of long span suspension bridge in time domain under strong wind loading is computed. Modeling method for generating non-stationary fluctuating winds with probabilistic model for n...The non-stationary buffeting response of long span suspension bridge in time domain under strong wind loading is computed. Modeling method for generating non-stationary fluctuating winds with probabilistic model for non-stationary strong wind fields is first presented. Non-stationary wind forces induced by strong winds on bridge deck and tower are then given a brief introduction. Finally,Non-stationary buffeting response of Pulite Bridge in China,a long span suspension bridge,is computed by using ANSYS software under four working conditions with different combination of time-varying mean wind and time-varying variance. The case study further confirms that it is necessity of considering non-stationary buffeting response for long span suspension bridge under strong wind loading,rather than only stationary buffeting response.展开更多
Objective: To observe and compare the effect of traditional Chinese medicine (TCM) combined with chemotherapy (CT) on immune function and quality of life (QOL)of patients with non-small cell lung cancer (NSCLC) in sta...Objective: To observe and compare the effect of traditional Chinese medicine (TCM) combined with chemotherapy (CT) on immune function and quality of life (QOL)of patients with non-small cell lung cancer (NSCLC) in stage Ⅲ-Ⅳ. Methods: One hundred cases with stage Ⅲ-Ⅳ NSCLC were randomly divided into two groups. The treated group (n=50) received CT combined with TCM, and the control group received CT alone. The percentage of T lymphocyte subset in peripheral blood and the change of natural killer (NK) cell count were observed after treatment. The QOL and tolerance of CT were also compared between the two groups after treatment. Results: In the treated group, CD3 cell count, CD4 cell count, CD4/ CDg ratio and NK cell activity were higher than those in control group, while CD8 cell count in the treated group was lower than that in the control group (P<0.05), and QOL and tolerance of CT in the treated group were also better (P<0.05). Conclusion: TCM combined with CT could raise the patients' ability in tolerating CT in stage Ⅲ-ⅣNSCLC.展开更多
The publication of ISO 15686-5 is significant for studies related to the life-cycle costs of buildings. Among the many economic evaluation methods, the NPV method is recommended for use by this standard. This stu...The publication of ISO 15686-5 is significant for studies related to the life-cycle costs of buildings. Among the many economic evaluation methods, the NPV method is recommended for use by this standard. This study explains the concept and method of PV, and then provides an explanation of the concept and method of NPV, and points out the limitations in the practical application of the method.展开更多
Objectives To study wheth- er change of BNP levels reflect the change of cardiac function and to investigate the short - term prognostic potential of BNP and QOL in patients with CHF. Methods 96 consecutive patients a...Objectives To study wheth- er change of BNP levels reflect the change of cardiac function and to investigate the short - term prognostic potential of BNP and QOL in patients with CHF. Methods 96 consecutive patients admittedwith CHF between September 2002 and January 2003 were stud- ied , upon entry the study, BNP levels were measured, Patients administered the disease - specificquality of life questionnaire Minnesota living with heart failure questionnaire (LiHFe) within 1 day. BNP levels and administering LiHFe were repeated three months later. Results BNP levels were increased proportional to the severity of cardiac function. Physical domain and total score of LiHFe were significantly correlated to the severity of CHF ( p < 0. 05 ). BNP levels were de- creased in improving group(p =0. 032) . In deteriora- ting group BNP levels increased (P = 0. 043 ) . Kaplan - meier analysis according to BNP level cutoff point 150 ng/1, the life curve of higher BNP level group was significantly lower than the lower group ( p = 0. 001 ) . In univariate logistic regression, NYHA class, BNP, LVEF, LVEDD, heart size, total score of LiHFe, phys- ical domain of LiHFe and the emotional domain of LiH- Fe were all significant prognostic factors of CHF ( p < 0. 05 for all). While in multiple regression, only BNP level( p = 0. 036) and the emotional domain of LiHFe ( p = 0. 025 ) were independent prognostic factors. Conclusions Change of BNP reflects the treatment efficacy of CHF. BNP and QOL are the two major short - time prognostic factors of the chronic heart failure patients.展开更多
基金Project supported by the National Natural Science Foundation of China(No. 10571024)the Natural Science Foundation of Henan Province of China (No.200510078005)the Science Foundation of Educational Department of Henan Province of China (No.200511051700)
文摘The paper concerns Cauchy,problem for one-dimensional hydromagnetic dynamics with dissipative terms. When the dissipation coefficient is equal to zero it is shown that the smooth solutions develop shocks in the finite time if the initial amounts of entropy and magnetic field are smaller than those of sound waves; when it is larger than zero, and the initial amounts of entropyI this dissipation coefficient and the magnetic field in each period are smaller than those of sound Waves, then the smooth solutions blow up in the finite time. Moreover, the life-span of the smooth solution is given.
基金supported in part by the NNSF of China(11271323,91330105)the Zhejiang Provincial Natural Science Foundation of China(LZ13A010002)the Henan Provincial Natural Science Foundation of China(152300410226)
文摘In this article, we investigate the lower bound of life-span of classical solutions of the hyperbolic geometry flow equations in several space dimensions with ＂small＂ initial data. We first present some estimates on solutions of linear wave equations in several space variables. Then, we derive a lower bound of the life-span of the classical solutions to the equations with ＂small＂ initial data.
文摘Dietary γ-amino butyric acid (GABA) has been suggested to decrease systolic blood pressure. This study aimed to ex-amine the effects of dietary GABA on the life span of stroke-prone spontaneously hypertensive rats (SHRSPs). In this study, life span was determined for SHRSPs provided 1% NaCl solution or 0.01% GABA in 1% NaCl solution as drinking water. The life span of the GABA-fed group (76.3 ± 1.65 days) was significantly shorter than that of the control group (81.6 ± 0.88 days). The results of this study may not be applicable to humans. Future studies will be necessary to elucidate the mechanism underlying this phenomenon.
文摘Drosophila melanogaster mutants with deficient kynurenine (KYN) formation from tryptophan (TRP) have longer life span than wild type flies. Administration of alpha-methyl-TRP and 5-methyl-TRY, the inhibitors of TRP-KYN metabolism, prolonged life span in wild-type flies. Both inhibitors are not available for human use. Berberine, an isoquinoline alkaloid isolated from berberis aristata is known as the herb widely used in traditional Chinese and Indian medicine. Berberin is a strong inhibitor of the enzyme catalyzing TRP conversion into KYN. Considering this particular feature we investigated the effect of berberine on life-and health-span in wild-type Drosophila melanogaster. The results of our study showed that Berberine extended mean, median and maximum life span of female flies. Berberine did not affect the number of pupae of filial generation and decreased their lethality. Berberine increased locomotor activity (vertical climbing). The results of the study suggest that berberine prolongs life- and improves health-span of Drosophila melanogaster. Berberine might be a candidate drug for prevention and treatment of aging and aging-associated medical and psychiatric disorders.
基金supported by the National Basic Research Program of China (Grant 2012CB937500)the National Natural Science Foundations of China (Grants 11172304 and 11202210)
文摘In this paper, ultrasonic （20 kHz） fatigue tests were performed on specimens of a high-strength steel in very high cycle fatigue （VHCF） regime. Experimental results showed that for most tested specimens failed in a VHCF regime, a fatigue crack originated from the interior of specimen with a fish-eye pattern, which contained a fine granular area （FGA） centered by an inclusion as the crack origin. Then, a two-parameter model is proposed to predict the fatigue life of high-strength steels with fish-eye mode failure in a VHCF regime, which takes into account the inclusion size and the FGA size. The model was verified by the data of present experiments and those in the literature. Furthermore, an analytic formula was obtained for estimating the equivalent crack growth rate within the FGA. The results also indicated that the stress intensity factor range at the front of the FGA varies within a small range, which is irrespective of stress amplitude and fatigue life.
文摘The ef fects of salinity on the copepod, A cartia tonsa in terms of daily egg production rate(EPR), hatching success, fecal pellet production rate(FPR), naupliar development time and survival, sex ratio, and total life span were determined in laboratory conditions through three experiments. In experiment 1, EPR, hatching success, and FPR of individual females were monitored at salinities of 13, 20, 35 and 45 during short-periods(seven consecutive days). Results show EPR was aff ected by salinity with the highest outputs recorded at 20 and 35, respectively, which were considerably higher than those at 13 and 45. Mean FPR was also higher in 35 and 20. In experiment 2, the same parameters were evaluated over total life span of females(long-term study). The best EPR and FPR were observed in 35, which was statistically higher than at 13 and 20. In experiment 3, survival rates of early nauplii until adult stage were lowest at a salinity of 13. The development time increased with increasing of salinity. Female percentage clearly decreased with increasing salinity. Higher female percentages(56.7% and 52.2%, respectively) were signifi cantly observed at two salinities of 13 and 20 compared to that at 35(25%). Total longevity of females was not af fected by salinity increment. Based on our results, for mass culture we recommend that a salinity of 35 be adopted due to higher reproductive performances, better feeding, and faster development of A. tonsa.
基金partially supported by the Doctor Start-up Funding and Natural Science Foundation of Chongqing University of Posts and Telecommunications(A2014-25 and A2014-106)partially supported by Scientific and Technological Research Program of Chongqing Municipal Education Commission(KJ1500403)+3 种基金the Basic and Advanced Research Project of CQCSTC(cstc2015jcyj A00008)partially supported by NSFC(11371384),partially supported by NSFC(11426047)the Basic and Advanced Research Project of CQCSTC(cstc2014jcyj A00040)the Research Fund of Chongqing Technology and Business University(2014-56-11)
文摘This paper deals with the Cauchy problem for a doubly singular parabolic equation with a weighted source ut=div｜u｜p-2um）＋｜x｜α uq ,（x,t）∈RN×（0,t）,where N ≥ 1, 1 〈 p 〈 2, m 〉 max（0,3 -p/N} satisfying 2 〈 p＋m 〈 3, q 〉 1, and（α 〉 N（3 - p - m） - p. We give the secondary critical exponent on the decay asymptotic behavior of an initial value at infinity for the existence and non-existence of global solutions of the Cauchy problem. Moreover, the life span of solutions is also studied.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.11802168 and 51575331)project funded by China Postdoctoral Science Foundation(No.2019M661458)
文摘Owing to the complex environmental conditions, suspension could induce complicated forces on submarine pipelines and even cause vortex-induced vibration, resulting in fatigue damage of pipelines. Through aiming at the 28-inch submarine pipeline in the East China Sea, the pipeline was segmented according to the similarity, considering the factors of pipe assembly, typhoon, current, wave and seabed topography. The effects of span length on natural frequency in each section of submarine pipeline were analyzed by finite element model. The maximum safe span length allowed by each pipeline section was verified by fatigue cumulative damage theory, and the fatigue life of each pipeline section were predicted. The results showed that each order natural frequency of the pipeline decreased with the increase of span length. The calculated results of empirical formulas were much smaller than those of the FEM analysis. The increase of the gap between the suspended pipeline and the seabed was beneficial to enhance the fatigue life of the suspended pipeline.
文摘Based on the theory of continuum damage mechanics,a bi-variable damage mechanics model is developed,which,according to thermodynamics,is accessible to derivation of damage driving force,damage evolution equation and damage evolution criteria. Furthermore,damage evolution equations of time rate are established by the generalized Drucker＇s postulate. The damage evolution equation of cycle rate is obtained by integrating the time damage evolution equations,and the fatigue life prediction method for smooth specimens under repeated loading with constant strain amplitude is constructed. Likewise,for notched specimens under the repeated loading with constant strain amplitude,the fatigue life prediction method is obtained on the ground of the theory of conservative integral in damage mechanics. Thus,the material parameters in the damage evolution equation can be obtained by reference to the fatigue test results of standard specimens with stress concentration factor equal to 1,2 and 3.
基金financial support from the Regional Government of Castilla-León(Project No.SA126G18)。
文摘Implications of the differences in leaf life span are still subject to debate in the field of ecophysiology.Since leaf traits associated with these differences may be decisive for determining the distribution of tree species,this topic is particularly relevant in the context of climate change.This study analyzes the effects of the differences in leaf life span on premature losses of leaf area owing to insect herbivory and to abiotic stress.Loss of leaf area may be an important determinant of total leaf carbon assimilation.Seven Mediterranean tree species,distributed on four sites with different climates were studied.The species exhibited strong differences in leaf life span and in leaf traits,especially leaf mass per unit area.Premature leaf area losses were estimated in response to insect herbivory and summer drought over two years.The results revealed that,despite having older leaf cohorts with more damage,species with longer leaf duration had lower area lost to herbivores and less damage due to accelerated senescence during the summer drought.With respect to the predicted increase in water stress,deciduous species are at a disadvantage due to their high premature loss of leaf area and thus loss of photosynthetic capacity.
文摘Considering the insulators ageing in a mixture of PVC and dye, set following operating conditions and time to ensure proper operation and perfect safety of industrial installations using insulated conductors. The results showed that the insulation carried out by the L.C main office was a good quality (on thermal aspect), because the resistance of the insulation is so high (i.e. 3940 Mega Ohms under normal conditions). The results showed a lifespan of 50 years at a temperature of 40°C (close to ambient temperature), plus minus 33 years at a temperature of 70°C;plus minus 22 years at a temperature of 100°C and 12 years at a temperature of 160°C. Furthermore, information on chemical attack, the results showed that PVC cables have poor resistance to sulfuric acid attack (having a pH of 1.5 and a density of 1.84 g/cm<sup>3</sup>). LC/Gecamines is able to produce locally a good quality of electrical cables.
文摘In this paper the authors consider Cauchy problem of first order quasilinear hyperbolic and prove that existence of its periodic solutions and estimates of life span of solutions. This results reveals the relationship of dissipation and smoothness of periodic solutions.
基金Sponsored by the National Natural Science Foundation of China(Grant No.51408174)Anhui Provincial Natural Science Foundation(Grant No.1408085QE95)+1 种基金China Postdoctoral Science Foundation(Grant No.2013M540511 and 2015T80652)Key University Science Research Project of Anhui Province(Grant No.KJ2016A294)
文摘The non-stationary buffeting response of long span suspension bridge in time domain under strong wind loading is computed. Modeling method for generating non-stationary fluctuating winds with probabilistic model for non-stationary strong wind fields is first presented. Non-stationary wind forces induced by strong winds on bridge deck and tower are then given a brief introduction. Finally,Non-stationary buffeting response of Pulite Bridge in China,a long span suspension bridge,is computed by using ANSYS software under four working conditions with different combination of time-varying mean wind and time-varying variance. The case study further confirms that it is necessity of considering non-stationary buffeting response for long span suspension bridge under strong wind loading,rather than only stationary buffeting response.
文摘Objective: To observe and compare the effect of traditional Chinese medicine (TCM) combined with chemotherapy (CT) on immune function and quality of life (QOL)of patients with non-small cell lung cancer (NSCLC) in stage Ⅲ-Ⅳ. Methods: One hundred cases with stage Ⅲ-Ⅳ NSCLC were randomly divided into two groups. The treated group (n=50) received CT combined with TCM, and the control group received CT alone. The percentage of T lymphocyte subset in peripheral blood and the change of natural killer (NK) cell count were observed after treatment. The QOL and tolerance of CT were also compared between the two groups after treatment. Results: In the treated group, CD3 cell count, CD4 cell count, CD4/ CDg ratio and NK cell activity were higher than those in control group, while CD8 cell count in the treated group was lower than that in the control group (P<0.05), and QOL and tolerance of CT in the treated group were also better (P<0.05). Conclusion: TCM combined with CT could raise the patients' ability in tolerating CT in stage Ⅲ-ⅣNSCLC.
文摘The publication of ISO 15686-5 is significant for studies related to the life-cycle costs of buildings. Among the many economic evaluation methods, the NPV method is recommended for use by this standard. This study explains the concept and method of PV, and then provides an explanation of the concept and method of NPV, and points out the limitations in the practical application of the method.
文摘Objectives To study wheth- er change of BNP levels reflect the change of cardiac function and to investigate the short - term prognostic potential of BNP and QOL in patients with CHF. Methods 96 consecutive patients admittedwith CHF between September 2002 and January 2003 were stud- ied , upon entry the study, BNP levels were measured, Patients administered the disease - specificquality of life questionnaire Minnesota living with heart failure questionnaire (LiHFe) within 1 day. BNP levels and administering LiHFe were repeated three months later. Results BNP levels were increased proportional to the severity of cardiac function. Physical domain and total score of LiHFe were significantly correlated to the severity of CHF ( p < 0. 05 ). BNP levels were de- creased in improving group(p =0. 032) . In deteriora- ting group BNP levels increased (P = 0. 043 ) . Kaplan - meier analysis according to BNP level cutoff point 150 ng/1, the life curve of higher BNP level group was significantly lower than the lower group ( p = 0. 001 ) . In univariate logistic regression, NYHA class, BNP, LVEF, LVEDD, heart size, total score of LiHFe, phys- ical domain of LiHFe and the emotional domain of LiH- Fe were all significant prognostic factors of CHF ( p < 0. 05 for all). While in multiple regression, only BNP level( p = 0. 036) and the emotional domain of LiHFe ( p = 0. 025 ) were independent prognostic factors. Conclusions Change of BNP reflects the treatment efficacy of CHF. BNP and QOL are the two major short - time prognostic factors of the chronic heart failure patients.
