This work is focused on a quasi-Euclidean space with UV cutoff, IR cutoff and symmetries. Mathematical analysis reveals that the UV cutoff results in the minimum structures of space. Dominated by rotational symmetry, ...This work is focused on a quasi-Euclidean space with UV cutoff, IR cutoff and symmetries. Mathematical analysis reveals that the UV cutoff results in the minimum structures of space. Dominated by rotational symmetry, the structure should be a local one in situ or on a sphere. Investigations show that a 10D minimum structure is a non-local one with transformability between in-situ state and spherical state due to its special topology. Based on the quantum behaviors of the 10D structure controlled by translational symmetry, IR cutoff determines two long-range interactions with dimensionless constants of ~1/137.036 and ~1/1.628E+38, respectively.展开更多
The quantitative structure-property relationship(QSPR) of anabolic androgenic steroids was studied on the half-wave reduction potential(E1/2) using quantum and physico-chemical molecular descriptors. The descriptors w...The quantitative structure-property relationship(QSPR) of anabolic androgenic steroids was studied on the half-wave reduction potential(E1/2) using quantum and physico-chemical molecular descriptors. The descriptors were calculated by semi-empirical calculations. Models were established using partial least square(PLS) regression and back-propagation artificial neural network(BP-ANN). The QSPR results indicate that the descriptors of these derivatives have significant relationship with half-wave reduction potential. The stability and prediction ability of these models were validated using leave-one-out cross-validation and external test set.展开更多
Metal-organic frameworks(MOFs)have been developed as an ideal platform for exploration of the relationship between intrinsic structure and catalytic activity,but the limited catalytic activity and stability has hamper...Metal-organic frameworks(MOFs)have been developed as an ideal platform for exploration of the relationship between intrinsic structure and catalytic activity,but the limited catalytic activity and stability has hampered their practical use in water splitting.Herein,we develop a bond length adjustment strategy for optimizing naphthalene-based MOFs that synthesized by acid etching Co-naphthalenedicarboxylic acid-based MOFs(donated as AE-CoNDA)to serve as efficient catalyst for water splitting.AE-CoNDA exhibits a low overpotential of 260 mV to reach 10 mA cm^(−2)and a small Tafel slope of 62 mV dec^(−1)with excellent stability over 100 h.After integrated AE-CoNDA onto BiVO_(4),photocurrent density of 4.3 mA cm^(−2)is achieved at 1.23 V.Experimental investigations demonstrate that the stretched Co-O bond length was found to optimize the orbitals hybridization of Co 3d and O 2p,which accounts for the fast kinetics and high activity.Theoretical calculations reveal that the stretched Co-O bond length strengthens the adsorption of oxygen-contained intermediates at the Co active sites for highly efficient water splitting.展开更多
China-ADS project, a continuous wave (CW) proton accelerator and aims to design and build an ADS demonstration facility has been proposed and launched actively in China. HWR ( =0.10) superconducting cavity with freque...China-ADS project, a continuous wave (CW) proton accelerator and aims to design and build an ADS demonstration facility has been proposed and launched actively in China. HWR ( =0.10) superconducting cavity with frequency of 162.5 MHz is applied to one of the parallel injectors prompted by Institute of Modern Physics (IMP)[1].展开更多
Dispersion fuels,knowned for their excellent safety performance,are widely used in advanced reactors,such as hightemperature gas-cooled reactors.Compared with deterministic methods,the Monte Carlo method has more adva...Dispersion fuels,knowned for their excellent safety performance,are widely used in advanced reactors,such as hightemperature gas-cooled reactors.Compared with deterministic methods,the Monte Carlo method has more advantages in the geometric modeling of stochastic media.The explicit modeling method has high computational accuracy and high computational cost.The chord length sampling(CLS)method can improve computational efficiency by sampling the chord length during neutron transport using the matrix chord length?s probability density function.This study shows that the excluded-volume effect in realistic stochastic media can introduce certain deviations into the CLS.A chord length correction approach is proposed to obtain the chord length correction factor by developing the Particle code based on equivalent transmission probability.Through numerical analysis against reference solutions from explicit modeling in the RMC code,it was demonstrated that CLS with the proposed correction method provides good accuracy for addressing the excludedvolume effect in realistic infinite stochastic media.展开更多
AIM:To elucidate whether differences exist in the impact on retarding the elongation of axial length(AL)among children with myopia when utilizing orthokeratology(ortho-k)lenses employing the corneal refractive therapy...AIM:To elucidate whether differences exist in the impact on retarding the elongation of axial length(AL)among children with myopia when utilizing orthokeratology(ortho-k)lenses employing the corneal refractive therapy(CRT)design versus those employing the vision shaping treatment(VST)design.METHODS:This retrospective clinical trial aimed to collect and analyze AL data from individuals who wore ortho-k lenses for three years.A total of 654 subjects were enrolled and prescribed one of the three specific brands of ortho-k lenses:CRT,Euclid,and Mouldway.The study’s primary focus was to compare the rates of AL elongation and myopic progression across these three brands of ortho-k lenses.RESULTS:In the 3-year follow-up,the AL elongation exhibited variations of 0.73±0.36 mm in the CRT lens group,0.59±0.37 mm in the Euclid lens group,and 0.63±0.38 mm in the Mouldway lens group.A noteworthy disparity emerged between the CRT and Mouldway groups(P<0.01),as well as between the CRT and Euclid groups(P<0.001).Additionally,it was observed that 32.1%of participants who wore CRT lenses experienced a decelerated progression of myopia,in contrast to 47.2%in the Euclid group and 44.4%in the Mouldway group.Statistical analyses revealed a statistically significant distinction between the CRT and Euclid groups(P<0.01),and similarly,the CRT group demonstrated a statistically significant difference when compared to the Mouldway group(P<0.05).CONCLUSION:Ortho-k lenses represent a pragmatic strategy for mitigating the advancement of myopia.In contradistinction to ortho-k lenses utilizing the CRT design,those employing the VST design exhibited a more favorable impact regarding retarding AL elongation.展开更多
Internode number and length are the foundation to constitute plant height, ear height and the above-ground spatial structure of maize plant. In this study, segregating populations were constructed between EHel with ex...Internode number and length are the foundation to constitute plant height, ear height and the above-ground spatial structure of maize plant. In this study, segregating populations were constructed between EHel with extremely low ear height and B73. Through the SNP-based genotyping and phenotypic characterization, 13 QTL distributed on the chromosomes (Chrs) of Chr1, Chr2, Chr5-Chr8 were detected for four traits of internode no. above ear (INa), average internode length above ear (ILaa), internode no. below ear (INb), and average internode length below ear (ILab). Phenotypic variation explained (PVE) by a single QTL ranged from 6.82% (qILab2-2) to 12.99% (qILaa5). Zm00001d016823 within the physical region of qILaa5, the major QTL for ILaa with the largest PVE was determined as the candidate through the genomic annotation and sequence alignment between EHel and B73. Product of Zm00001d016823 was annotated as a WEB family protein homogenous to At1g75720. qRT-PCR assay showed that Zm00001d016823 highly expressed within the tissue of internode, exhibiting statistically higher expression levels among internodes of IN4 to IN7 in EHel than those in B73 (P Zm00001d016823 might provide novel insight into molecular mechanism beyond phytohormones controlling internode development in maize.展开更多
In this work,the flow surrounding the train was obtained using a detached eddy simulation(DES)for slipstream analysis.Two different streamlined nose lengths were investigated:a short nose(4 m)and a long nose(9 m).The ...In this work,the flow surrounding the train was obtained using a detached eddy simulation(DES)for slipstream analysis.Two different streamlined nose lengths were investigated:a short nose(4 m)and a long nose(9 m).The time-average slipstream velocity and the time-average slipstream pressure along the car bodies were compared and explained in detail.In addition to the time-averaged values,the _(max)imum velocities and the pressure peak-to-peak values around the two trains were analyzed.The result showed that the nose length affected the slipstream velocity along the entire train length at the lower and upper regions of the side of the train.However,no significant effect was recognized at the middle height of the train along its length,except in the nose region.Moreover,within the train’s side regions(y=2.0-2.5 m and z=2-4 m)and(y=2.5-3.5 m and z=0.2-0.7 m),the ratio of slipstream velocity U_(max) between the short and long nose trains was notably higher.This occurrence also manifested at the train’s upper section,specifically where y=0-2.5 m and z=4.2-5.0 m.Similarly,regarding the ratio of _(max)imum pressure peak-to-peak values Cp-p_(max),significant regions were observed at the train’s side(y=1.8-2.6 m and z=1-4 m)and above the train(y=0-2 m and z=3.9-4.8 m).展开更多
The safety and stability of high-speed maglev trains traveling on viaducts in crosswinds critically depend on their aerodynamic characteristics.Therefore,this paper uses an improved delayed detached eddy simulation(ID...The safety and stability of high-speed maglev trains traveling on viaducts in crosswinds critically depend on their aerodynamic characteristics.Therefore,this paper uses an improved delayed detached eddy simulation(IDDES)method to investigate the aerodynamic features of high-speed maglev trains with different marshaling lengths under crosswinds.The effects of marshaling lengths(varying from 3-car to 8-car groups)on the train’s aerodynamic performance,surface pressure,and the flow field surrounding the train were investigated using the three-dimensional unsteady compressible Navier-Stokes(N-S)equations.The results showed that the marshaling lengths had minimal influence on the aerodynamic performance of the head and middle cars.Conversely,the marshaling lengths are negatively correlated with the time-average side force coefficient(CS)and time-average lift force coefficient(Cl)of the tail car.Compared to the tail car of the 3-car groups,the CS and Cl fell by 27.77%and 18.29%,respectively,for the tail car of the 8-car groups.It is essential to pay more attention to the operational safety of the head car,as it exhibits the highest time average CS.Additionally,the mean pressure difference between the two sides of the tail car body increased with the marshaling lengths,and the side force direction on the tail car was opposite to that of the head and middle cars.Furthermore,the turbulent kinetic energy of the wake structure on the windward side quickly decreased as marshaling lengths increased.展开更多
AIM:To investigate the impact of multifocal gas permeable contact lens(MFGPCL)in various add power and distance/near area allocation on short-term changes of choroidal thickness(ChT),axial length(AL),and retinal defoc...AIM:To investigate the impact of multifocal gas permeable contact lens(MFGPCL)in various add power and distance/near area allocation on short-term changes of choroidal thickness(ChT),axial length(AL),and retinal defocus profile in young adults.METHODS:Seventeen young adults(2 males and 15 females;age 23.17±4.48y)were randomly assigned to wear two designs binocularly with a one-week washout period in between.Total of four MFGPCL designs were assessed.All designs were distance-center that varied in two add power(+1.50 and 3.00 D)and/or two distance zone(DZ)diameters(1.50 and 3.00 mm;design A:DZ 1.5/add 3.0,B:DZ 1.5/add 1.5,C:DZ 3.0/add 3.0,D:DZ 3.0/add 1.5).ChT,AL,and peripheral refraction data were collected on each subject at baseline,on days 1 and 7 of MFGPCL daily wear.ChT was assessed in four quadrants using a spectraldomain optical coherence tomography.RESULTS:AL was shortened by-26±44μm with lens C,-18±27μm with lens D,-13±29μm with lens A,and-8±30μm with lens B(all P<0.05).A significant overall increase in ChT was observed with all 4 designs(lens A:+6±6μm,B:+3±7μm,C:+8±7μm,and D:+8±7μm).Temporal and superior choroid exhibited more choroidal thickening associated with MFGPCL.All designs induced significant relative peripheral myopia(RPM)beyond the central 20o across the horizontal meridian in both nasal and temporal fields(P<0.05).CONCLUSION:MFGPCLs show a significant influence on ChT and AL,which are associated with significant increase in RPM after short-term wear.The reliability and feasibility of quantifying short-term changes in ChT support its use as a promising marker for the long-term efficacy of myopia-controlling treatments.展开更多
In previous work, the electron radius was identified as the “actual electron radius.” However, this is more accurately described as the electron radius at rest. This study reexamines the electron with an emphasis on...In previous work, the electron radius was identified as the “actual electron radius.” However, this is more accurately described as the electron radius at rest. This study reexamines the electron with an emphasis on the electron radius under motion, incorporating the effects of length contraction. The findings suggest that the radius is subject to Lorentz contraction, which has interesting implications for relativistic effects at the subatomic level.展开更多
The breakdown of the Heisenberg Uncertainty Principle occurs when energies approach the Planck scale, and the corresponding Schwarzschild radius becomes similar to the Compton wavelength. Both of these quantities are ...The breakdown of the Heisenberg Uncertainty Principle occurs when energies approach the Planck scale, and the corresponding Schwarzschild radius becomes similar to the Compton wavelength. Both of these quantities are approximately equal to the Planck length. In this context, we have introduced a model that utilizes a combination of Schwarzschild’s radius and Compton length to quantify the gravitational length of an object. This model has provided a novel perspective in generalizing the uncertainty principle. Furthermore, it has elucidated the significance of the deforming linear parameter β and its range of variation from unity to its maximum value.展开更多
Grain size is one of the determinants of grain yield,and identifying the genetic loci that control grain size will be helpful for increasing grain yield.In our previous study,a quantitative trait locus(QTL)for grain l...Grain size is one of the determinants of grain yield,and identifying the genetic loci that control grain size will be helpful for increasing grain yield.In our previous study,a quantitative trait locus(QTL)for grain length(GL),QGl.cau-2D.1,was identified from an F2 population developed from the cross between the natural(TAA10)and synthetic(XX329)allohexaploid wheat.In the present study,we mainly fine mapped and validated its genetic effects.To this end,multiple near-isogenic lines(NILs)were obtained through marker-assisted selection with TAA10 as the recurrent parent.The secondary populations derived from 25 heterozygous recombinants were used for fine mapping of QGl.cau-2D.1,and the allele from XX329 significantly increased GL,thousand-grain weight(TGW),total spikelet number per spike(TSN)and spike compactness(SC).Using NILs for XX329(2D+)and TAA10(2D−),we determined the genetic and pleiotropic effects of QGl.cau-2D.1.The target sequences were aligned with the wheat reference genome RefSeq v2.1 and spanned an~0.9 Mb genomic region.TraesCS2D03G0114900(ortholog of Os03g0594700)was predicted as the candidate gene based on whole-genome re-sequencing and expression analyses.In summary,the map-based cloning of QGl.cau-2D.1 will be useful for improving grain weight with enhanced GL and TSN.展开更多
The rotation of the Earth and the related length of the day (LOD) are predominantly affected by tidal dissipation through the Moon and the growth of the Earth’s core. Due to the increased concentration of mass around...The rotation of the Earth and the related length of the day (LOD) are predominantly affected by tidal dissipation through the Moon and the growth of the Earth’s core. Due to the increased concentration of mass around the rotation axis of the spinning Earth during the growth of the core the rotation should have been accelerated. Controversially the tidal dissipation by the Moon, which is mainly dependent on the availability of open shallow seas and the kind of Moon escape from a nearby position, acts towards a deceleration of the rotating Earth. Measurements of LOD for Phanerozoic and Precambrian times open ways to solve questions concerning the geodynamical history of the Earth. These measurements encompass investigations of growth patterns in fossils and depositional patterns in sediments (Cyclostratigraphy, Tidalites, Stromatolites, Rhythmites). These patterns contain information on the LOD and on the changing distance between Earth and Moon and can be used as well for a discussion about the growth of the Earth’s core. By updating an older paper with its simple approach as well as incorporating newly published results provided by the geoscientific community, a moderate to fast growth of the core in a hot early Earth will be favored controversially to the assumption of a delayed development of the core in an originally cold Earth. Core development with acceleration of Earth’s rotation and the contemporaneous slowing down due to tidal dissipation during the filling of the ocean may significantly interrelate.展开更多
BACKGROUND Simple bone cysts(SBC)are benign tumor-like bone lesions typically identified in children.While SBC may lead to growth disturbances or growth arrest,such cases are uncommon.The mechanisms behind these obser...BACKGROUND Simple bone cysts(SBC)are benign tumor-like bone lesions typically identified in children.While SBC may lead to growth disturbances or growth arrest,such cases are uncommon.The mechanisms behind these observations remain unclear.Additionally,research on the etiology of SBC remains inconclusive,and there has been no consensus on the appropriate timing and methodology for treatment.CASE SUMMARY Here,we present our experience in the successful surgical management of a 10-year-old girl with SBC,who presented with a pathological fracture complicated by malunion of the displaced fracture,varus deformity,and limb length discrepancy.We hypothesized two possible etiologies for the patient’s growth arrest and subsequent humerus varus deformity:(1)Direct disruption of the physis by fluid from the cyst itself;and(2)damage to the epiphysis due to repetitive pathological fractures associated with SBC.In addressing this case,surgical intervention was undertaken to correct the proximal humerus varus deformity.This approach offered the advantages of simultaneously correcting angular abnormalities,achieving mild limb lengthening,providing definitive SBC treatment,and reducing the overall treatment duration.CONCLUSION As per current literature,acute correction of acute angular deformity in proximal humeral SBC is not well comprehended.However,in this specific case,acute correction was considered an optimal solution.展开更多
One of the new methods for ensuring that the battery in a thermal energy storage system is kept at the proper temperature is the heat pipe-based ThermalManagement System(TMS).In this study,the improvement of cooling p...One of the new methods for ensuring that the battery in a thermal energy storage system is kept at the proper temperature is the heat pipe-based ThermalManagement System(TMS).In this study,the improvement of cooling performance of a heat pipe based TMS is examined through the variation of condenser section length of heat pipes in an array.The TMSs with an array of heat pipes with different condenser section lengths are considered.The system performances are evaluated using a validated numerical method.The results show that a heat pipebased TMS provides the best cooling performance when a wavy-like variation is employed and when the condenser section length of the last set of the heat pipe in the array is greater than that of the penultimate set.The maximum cell temperature and the maximum temperature difference within the cell of this TMS are decreased by 4.2 K and 1.1 K,respectively,when compared to the typical heat pipe based TMS with zero variation in its condenser section length.Conclusively,the strategy offers an improvement in the thermal uniformity for all the TMS cases.展开更多
The fundamental frequency plays a significant part in understanding and perceiving the pitch of a sound. The pitch is a fundamental attribute employed in numerous speech-related works. For fundamental frequency extrac...The fundamental frequency plays a significant part in understanding and perceiving the pitch of a sound. The pitch is a fundamental attribute employed in numerous speech-related works. For fundamental frequency extraction, several algorithms have been developed which one to use relies on the signal’s characteristics and the surrounding noise. Thus, the algorithm’s noise resistance becomes more critical than ever for precise fundamental frequency estimation. Nonetheless, numerous state-of-the-art algorithms face struggles in achieving satisfying outcomes when confronted with speech recordings that are noisy with low signal-to-noise ratio (SNR) values. Also, most of the recent techniques utilize different frame lengths for pitch extraction. From this point of view, This research considers different frame lengths on male and female speech signals for fundamental frequency extraction. Also, analyze the frame length dependency on the speech signal analytically to understand which frame length is more suitable and effective for male and female speech signals specifically. For the validation of our idea, we have utilized the conventional autocorrelation function (ACF), and state-of-the-art method BaNa. This study puts out a potent idea that will work better for speech processing applications in noisy speech. From experimental results, the proposed idea represents which frame length is more appropriate for male and female speech signals in noisy environments.展开更多
In the United States, the costs of health care have become a major burden for the health care system. In order to address this problem, the hospitals of Syracuse, New York, developed programs to provide subacute and c...In the United States, the costs of health care have become a major burden for the health care system. In order to address this problem, the hospitals of Syracuse, New York, developed programs to provide subacute and complex care. The Subacute programs provided patient transportation services for dialysis and other types of care outside hospitals. They also developed programs for services such as intravenous therapy in nursing homes. The Complex Care Programs, such as intravenous therapy and mental health services, have provided alternatives to extended care in hospitals. During the past five years, utilization of these programs has varied, declining between 2019 and 2022, and then increasing between 2022 and 2024. The programs have avoided the need for 1530 - 2974 patient days in hospitals. The programs saved the Syracuse hospitals approximately $600 per inpatient day. This amounted to savings of $918,000 - $1,784,400 per year. These programs demonstrated how relatively small mechanisms can save large amounts of health care resources.展开更多
Productivity and international energy price shocks are reflected in PPI and CPI via industrial chains.China’s in-depth participation into the global value chains has increasingly lengthened its industrial production ...Productivity and international energy price shocks are reflected in PPI and CPI via industrial chains.China’s in-depth participation into the global value chains has increasingly lengthened its industrial production chains.The question is how the changing length of production chains will affect CPI and PPI,as well as CPI-PPI correlation?By constructing a global input-output price model,this paper offers a theoretical discussion on the impact of production chain length on the CPI-PPI divergence.Our findings suggest that the price shock of international bulk commodities has a greater impact on China’s PPI than that on CPI.The effects on both China’s PPI and CPI estimated by using the single-country input-output model are higher than the results estimated with the global input-output model.However,the difference between CPI and PPI variations estimated with the global input-output model is greater than the result estimated with the single-country input-output model,which supports the view that the lengthening of production chains,especially international production chains,leads to a divergence between CPI and PPI.Empirical results based on cross-national panel data also suggest that the lengthening of production chains has reduced the CPI-PPI correlation for countries,i.e.the lengthening of production chains has increased the PPI-CPI divergence.That is to say,policymakers should target not just CPI in maintaining price stability,but instead focus on the stability of both PPI and CPI.Efforts can be made to proactively adjust the price index system,and formulate the industrial chain price index.展开更多
Background: In-hospital mortality is a key indicator of the quality of care. Studies so far have demonstrated the influence of patient and hospital-related factors on in-hospital mortality. Currently, new variables, s...Background: In-hospital mortality is a key indicator of the quality of care. Studies so far have demonstrated the influence of patient and hospital-related factors on in-hospital mortality. Currently, new variables, such as components of metabolic syndrome as comorbid conditions, are being incorporated as independent risk factors. We aimed to identify which individual, clinical and hospital characteristics are related to hospital mortality. Objectives: Demonstrate that the Cox proportional hazard model is not appropriate for the analysis of hospital mortality data when diagnostic-related groups are incorporated in the covariate structure. Methods: A retrospective single-center observational study design was used. Sampling was conducted between January 2016 and December 2018. Patients over 10 years, admitted to the emergency department with a precited stay of at least 1 hour were included. Multivariate Cox regression for survival data analyses was employed to analyze the data. Results: The sample consisted of 5897 patients. The mean age of all patients was 32.21 ± 0.29 years old, and the mean length of stay (LOS) was 9.47 ± 0.16 hours. We also categorized patients according to five Diagnosis Related Groups (DGR). Among the patients,1308 suffered from acute leukemia, 1127 had endocrine diseases, 1173 with kidney diseases, and 1016 had respiratory problems. At least one component of metabolic syndrome was present in 27.5% of the patients. During the observation period, 2299 (39%) died in hospital, and 3598 (61%) were discharged alive. We used the multivariate Cox regression non-proportional hazard model to evaluate the joint effect of these factors on the “Length of Stay” or LOS (the dependent variable of Cox regression). Age at admission, the presence of metabolic syndrome, and the DRG were significantly associated with the LOS.展开更多
文摘This work is focused on a quasi-Euclidean space with UV cutoff, IR cutoff and symmetries. Mathematical analysis reveals that the UV cutoff results in the minimum structures of space. Dominated by rotational symmetry, the structure should be a local one in situ or on a sphere. Investigations show that a 10D minimum structure is a non-local one with transformability between in-situ state and spherical state due to its special topology. Based on the quantum behaviors of the 10D structure controlled by translational symmetry, IR cutoff determines two long-range interactions with dimensionless constants of ~1/137.036 and ~1/1.628E+38, respectively.
基金Project supported by the Postdoctoral Science Foundation of Central South University,ChinaProject(2015SK20823)supported by Science and Technology Project of Hunan Province,China+2 种基金Project(15A001)supported by Scientific Research Fund of Hunan Provincial Education Department,ChinaProject(CX2015B372)supported by Hunan Provincial Innovation Foundation for Postgraduate,ChinaProject supported by Innovation Experiment Program for University Students of Changsha University of Science and Technology,China
文摘The quantitative structure-property relationship(QSPR) of anabolic androgenic steroids was studied on the half-wave reduction potential(E1/2) using quantum and physico-chemical molecular descriptors. The descriptors were calculated by semi-empirical calculations. Models were established using partial least square(PLS) regression and back-propagation artificial neural network(BP-ANN). The QSPR results indicate that the descriptors of these derivatives have significant relationship with half-wave reduction potential. The stability and prediction ability of these models were validated using leave-one-out cross-validation and external test set.
基金supported by the National Key Research and Development Program of China (2022YFB4002100)the development project of Zhejiang Province's "Jianbing" and "Lingyan" (2023C01226)+4 种基金the National Natural Science Foundation of China (22278364, U22A20432, 22238008, 22211530045, and 22178308)the Fundamental Research Funds for the Central Universities (226-2022-00044 and 226-2022-00055)the Science Foundation of Donghai Laboratory (DH-2022ZY0009)the Startup Foundation for Hundred-Talent Program of Zhejiang UniversityScientific Research Fund of Zhejiang Provincial Education Department.
文摘Metal-organic frameworks(MOFs)have been developed as an ideal platform for exploration of the relationship between intrinsic structure and catalytic activity,but the limited catalytic activity and stability has hampered their practical use in water splitting.Herein,we develop a bond length adjustment strategy for optimizing naphthalene-based MOFs that synthesized by acid etching Co-naphthalenedicarboxylic acid-based MOFs(donated as AE-CoNDA)to serve as efficient catalyst for water splitting.AE-CoNDA exhibits a low overpotential of 260 mV to reach 10 mA cm^(−2)and a small Tafel slope of 62 mV dec^(−1)with excellent stability over 100 h.After integrated AE-CoNDA onto BiVO_(4),photocurrent density of 4.3 mA cm^(−2)is achieved at 1.23 V.Experimental investigations demonstrate that the stretched Co-O bond length was found to optimize the orbitals hybridization of Co 3d and O 2p,which accounts for the fast kinetics and high activity.Theoretical calculations reveal that the stretched Co-O bond length strengthens the adsorption of oxygen-contained intermediates at the Co active sites for highly efficient water splitting.
文摘China-ADS project, a continuous wave (CW) proton accelerator and aims to design and build an ADS demonstration facility has been proposed and launched actively in China. HWR ( =0.10) superconducting cavity with frequency of 162.5 MHz is applied to one of the parallel injectors prompted by Institute of Modern Physics (IMP)[1].
文摘Dispersion fuels,knowned for their excellent safety performance,are widely used in advanced reactors,such as hightemperature gas-cooled reactors.Compared with deterministic methods,the Monte Carlo method has more advantages in the geometric modeling of stochastic media.The explicit modeling method has high computational accuracy and high computational cost.The chord length sampling(CLS)method can improve computational efficiency by sampling the chord length during neutron transport using the matrix chord length?s probability density function.This study shows that the excluded-volume effect in realistic stochastic media can introduce certain deviations into the CLS.A chord length correction approach is proposed to obtain the chord length correction factor by developing the Particle code based on equivalent transmission probability.Through numerical analysis against reference solutions from explicit modeling in the RMC code,it was demonstrated that CLS with the proposed correction method provides good accuracy for addressing the excludedvolume effect in realistic infinite stochastic media.
文摘AIM:To elucidate whether differences exist in the impact on retarding the elongation of axial length(AL)among children with myopia when utilizing orthokeratology(ortho-k)lenses employing the corneal refractive therapy(CRT)design versus those employing the vision shaping treatment(VST)design.METHODS:This retrospective clinical trial aimed to collect and analyze AL data from individuals who wore ortho-k lenses for three years.A total of 654 subjects were enrolled and prescribed one of the three specific brands of ortho-k lenses:CRT,Euclid,and Mouldway.The study’s primary focus was to compare the rates of AL elongation and myopic progression across these three brands of ortho-k lenses.RESULTS:In the 3-year follow-up,the AL elongation exhibited variations of 0.73±0.36 mm in the CRT lens group,0.59±0.37 mm in the Euclid lens group,and 0.63±0.38 mm in the Mouldway lens group.A noteworthy disparity emerged between the CRT and Mouldway groups(P<0.01),as well as between the CRT and Euclid groups(P<0.001).Additionally,it was observed that 32.1%of participants who wore CRT lenses experienced a decelerated progression of myopia,in contrast to 47.2%in the Euclid group and 44.4%in the Mouldway group.Statistical analyses revealed a statistically significant distinction between the CRT and Euclid groups(P<0.01),and similarly,the CRT group demonstrated a statistically significant difference when compared to the Mouldway group(P<0.05).CONCLUSION:Ortho-k lenses represent a pragmatic strategy for mitigating the advancement of myopia.In contradistinction to ortho-k lenses utilizing the CRT design,those employing the VST design exhibited a more favorable impact regarding retarding AL elongation.
文摘Internode number and length are the foundation to constitute plant height, ear height and the above-ground spatial structure of maize plant. In this study, segregating populations were constructed between EHel with extremely low ear height and B73. Through the SNP-based genotyping and phenotypic characterization, 13 QTL distributed on the chromosomes (Chrs) of Chr1, Chr2, Chr5-Chr8 were detected for four traits of internode no. above ear (INa), average internode length above ear (ILaa), internode no. below ear (INb), and average internode length below ear (ILab). Phenotypic variation explained (PVE) by a single QTL ranged from 6.82% (qILab2-2) to 12.99% (qILaa5). Zm00001d016823 within the physical region of qILaa5, the major QTL for ILaa with the largest PVE was determined as the candidate through the genomic annotation and sequence alignment between EHel and B73. Product of Zm00001d016823 was annotated as a WEB family protein homogenous to At1g75720. qRT-PCR assay showed that Zm00001d016823 highly expressed within the tissue of internode, exhibiting statistically higher expression levels among internodes of IN4 to IN7 in EHel than those in B73 (P Zm00001d016823 might provide novel insight into molecular mechanism beyond phytohormones controlling internode development in maize.
基金Project(52202426)supported by the National Natural Science Foundation of ChinaProjects(15205723,15226424)supported by the Research Grants Council of the Hong Kong Special Administrative Region(SAR),China+1 种基金Project(K2021J041)supported by the Technology Research and Development Program of China RailwayProject(1-BD23)supported by The Hong Kong Polytechnic University,China。
文摘In this work,the flow surrounding the train was obtained using a detached eddy simulation(DES)for slipstream analysis.Two different streamlined nose lengths were investigated:a short nose(4 m)and a long nose(9 m).The time-average slipstream velocity and the time-average slipstream pressure along the car bodies were compared and explained in detail.In addition to the time-averaged values,the _(max)imum velocities and the pressure peak-to-peak values around the two trains were analyzed.The result showed that the nose length affected the slipstream velocity along the entire train length at the lower and upper regions of the side of the train.However,no significant effect was recognized at the middle height of the train along its length,except in the nose region.Moreover,within the train’s side regions(y=2.0-2.5 m and z=2-4 m)and(y=2.5-3.5 m and z=0.2-0.7 m),the ratio of slipstream velocity U_(max) between the short and long nose trains was notably higher.This occurrence also manifested at the train’s upper section,specifically where y=0-2.5 m and z=4.2-5.0 m.Similarly,regarding the ratio of _(max)imum pressure peak-to-peak values Cp-p_(max),significant regions were observed at the train’s side(y=1.8-2.6 m and z=1-4 m)and above the train(y=0-2 m and z=3.9-4.8 m).
基金supported by Wuyi University Hong Kong and Macao Joint Research and Development Fund(GrantsNos.2021WGALH15,2019WGALH17,2019WGALH15)the National Natural Science Foundation of China-Guangdong Joint Fund(GrantsNo.2019A1515111052)+2 种基金the National Natural Science Foundation of China(Grant No.52202426)a grant from the Research Grants Council(RGC)of the Hong Kong Special Administrative Region(SAR),China(Grants No.15205723)a grant from the Hong Kong Polytechnic University(Grant No.P0045325).
文摘The safety and stability of high-speed maglev trains traveling on viaducts in crosswinds critically depend on their aerodynamic characteristics.Therefore,this paper uses an improved delayed detached eddy simulation(IDDES)method to investigate the aerodynamic features of high-speed maglev trains with different marshaling lengths under crosswinds.The effects of marshaling lengths(varying from 3-car to 8-car groups)on the train’s aerodynamic performance,surface pressure,and the flow field surrounding the train were investigated using the three-dimensional unsteady compressible Navier-Stokes(N-S)equations.The results showed that the marshaling lengths had minimal influence on the aerodynamic performance of the head and middle cars.Conversely,the marshaling lengths are negatively correlated with the time-average side force coefficient(CS)and time-average lift force coefficient(Cl)of the tail car.Compared to the tail car of the 3-car groups,the CS and Cl fell by 27.77%and 18.29%,respectively,for the tail car of the 8-car groups.It is essential to pay more attention to the operational safety of the head car,as it exhibits the highest time average CS.Additionally,the mean pressure difference between the two sides of the tail car body increased with the marshaling lengths,and the side force direction on the tail car was opposite to that of the head and middle cars.Furthermore,the turbulent kinetic energy of the wake structure on the windward side quickly decreased as marshaling lengths increased.
基金the Deputyship for Research and Innovation,Ministry of Education in Saudi Arabia for funding this research work through the project(No.IFKSUOR3-433-1)。
文摘AIM:To investigate the impact of multifocal gas permeable contact lens(MFGPCL)in various add power and distance/near area allocation on short-term changes of choroidal thickness(ChT),axial length(AL),and retinal defocus profile in young adults.METHODS:Seventeen young adults(2 males and 15 females;age 23.17±4.48y)were randomly assigned to wear two designs binocularly with a one-week washout period in between.Total of four MFGPCL designs were assessed.All designs were distance-center that varied in two add power(+1.50 and 3.00 D)and/or two distance zone(DZ)diameters(1.50 and 3.00 mm;design A:DZ 1.5/add 3.0,B:DZ 1.5/add 1.5,C:DZ 3.0/add 3.0,D:DZ 3.0/add 1.5).ChT,AL,and peripheral refraction data were collected on each subject at baseline,on days 1 and 7 of MFGPCL daily wear.ChT was assessed in four quadrants using a spectraldomain optical coherence tomography.RESULTS:AL was shortened by-26±44μm with lens C,-18±27μm with lens D,-13±29μm with lens A,and-8±30μm with lens B(all P<0.05).A significant overall increase in ChT was observed with all 4 designs(lens A:+6±6μm,B:+3±7μm,C:+8±7μm,and D:+8±7μm).Temporal and superior choroid exhibited more choroidal thickening associated with MFGPCL.All designs induced significant relative peripheral myopia(RPM)beyond the central 20o across the horizontal meridian in both nasal and temporal fields(P<0.05).CONCLUSION:MFGPCLs show a significant influence on ChT and AL,which are associated with significant increase in RPM after short-term wear.The reliability and feasibility of quantifying short-term changes in ChT support its use as a promising marker for the long-term efficacy of myopia-controlling treatments.
文摘In previous work, the electron radius was identified as the “actual electron radius.” However, this is more accurately described as the electron radius at rest. This study reexamines the electron with an emphasis on the electron radius under motion, incorporating the effects of length contraction. The findings suggest that the radius is subject to Lorentz contraction, which has interesting implications for relativistic effects at the subatomic level.
文摘The breakdown of the Heisenberg Uncertainty Principle occurs when energies approach the Planck scale, and the corresponding Schwarzschild radius becomes similar to the Compton wavelength. Both of these quantities are approximately equal to the Planck length. In this context, we have introduced a model that utilizes a combination of Schwarzschild’s radius and Compton length to quantify the gravitational length of an object. This model has provided a novel perspective in generalizing the uncertainty principle. Furthermore, it has elucidated the significance of the deforming linear parameter β and its range of variation from unity to its maximum value.
基金supported by the National Key Research and Development Program of China(32172069).
文摘Grain size is one of the determinants of grain yield,and identifying the genetic loci that control grain size will be helpful for increasing grain yield.In our previous study,a quantitative trait locus(QTL)for grain length(GL),QGl.cau-2D.1,was identified from an F2 population developed from the cross between the natural(TAA10)and synthetic(XX329)allohexaploid wheat.In the present study,we mainly fine mapped and validated its genetic effects.To this end,multiple near-isogenic lines(NILs)were obtained through marker-assisted selection with TAA10 as the recurrent parent.The secondary populations derived from 25 heterozygous recombinants were used for fine mapping of QGl.cau-2D.1,and the allele from XX329 significantly increased GL,thousand-grain weight(TGW),total spikelet number per spike(TSN)and spike compactness(SC).Using NILs for XX329(2D+)and TAA10(2D−),we determined the genetic and pleiotropic effects of QGl.cau-2D.1.The target sequences were aligned with the wheat reference genome RefSeq v2.1 and spanned an~0.9 Mb genomic region.TraesCS2D03G0114900(ortholog of Os03g0594700)was predicted as the candidate gene based on whole-genome re-sequencing and expression analyses.In summary,the map-based cloning of QGl.cau-2D.1 will be useful for improving grain weight with enhanced GL and TSN.
文摘The rotation of the Earth and the related length of the day (LOD) are predominantly affected by tidal dissipation through the Moon and the growth of the Earth’s core. Due to the increased concentration of mass around the rotation axis of the spinning Earth during the growth of the core the rotation should have been accelerated. Controversially the tidal dissipation by the Moon, which is mainly dependent on the availability of open shallow seas and the kind of Moon escape from a nearby position, acts towards a deceleration of the rotating Earth. Measurements of LOD for Phanerozoic and Precambrian times open ways to solve questions concerning the geodynamical history of the Earth. These measurements encompass investigations of growth patterns in fossils and depositional patterns in sediments (Cyclostratigraphy, Tidalites, Stromatolites, Rhythmites). These patterns contain information on the LOD and on the changing distance between Earth and Moon and can be used as well for a discussion about the growth of the Earth’s core. By updating an older paper with its simple approach as well as incorporating newly published results provided by the geoscientific community, a moderate to fast growth of the core in a hot early Earth will be favored controversially to the assumption of a delayed development of the core in an originally cold Earth. Core development with acceleration of Earth’s rotation and the contemporaneous slowing down due to tidal dissipation during the filling of the ocean may significantly interrelate.
文摘BACKGROUND Simple bone cysts(SBC)are benign tumor-like bone lesions typically identified in children.While SBC may lead to growth disturbances or growth arrest,such cases are uncommon.The mechanisms behind these observations remain unclear.Additionally,research on the etiology of SBC remains inconclusive,and there has been no consensus on the appropriate timing and methodology for treatment.CASE SUMMARY Here,we present our experience in the successful surgical management of a 10-year-old girl with SBC,who presented with a pathological fracture complicated by malunion of the displaced fracture,varus deformity,and limb length discrepancy.We hypothesized two possible etiologies for the patient’s growth arrest and subsequent humerus varus deformity:(1)Direct disruption of the physis by fluid from the cyst itself;and(2)damage to the epiphysis due to repetitive pathological fractures associated with SBC.In addressing this case,surgical intervention was undertaken to correct the proximal humerus varus deformity.This approach offered the advantages of simultaneously correcting angular abnormalities,achieving mild limb lengthening,providing definitive SBC treatment,and reducing the overall treatment duration.CONCLUSION As per current literature,acute correction of acute angular deformity in proximal humeral SBC is not well comprehended.However,in this specific case,acute correction was considered an optimal solution.
文摘One of the new methods for ensuring that the battery in a thermal energy storage system is kept at the proper temperature is the heat pipe-based ThermalManagement System(TMS).In this study,the improvement of cooling performance of a heat pipe based TMS is examined through the variation of condenser section length of heat pipes in an array.The TMSs with an array of heat pipes with different condenser section lengths are considered.The system performances are evaluated using a validated numerical method.The results show that a heat pipebased TMS provides the best cooling performance when a wavy-like variation is employed and when the condenser section length of the last set of the heat pipe in the array is greater than that of the penultimate set.The maximum cell temperature and the maximum temperature difference within the cell of this TMS are decreased by 4.2 K and 1.1 K,respectively,when compared to the typical heat pipe based TMS with zero variation in its condenser section length.Conclusively,the strategy offers an improvement in the thermal uniformity for all the TMS cases.
文摘The fundamental frequency plays a significant part in understanding and perceiving the pitch of a sound. The pitch is a fundamental attribute employed in numerous speech-related works. For fundamental frequency extraction, several algorithms have been developed which one to use relies on the signal’s characteristics and the surrounding noise. Thus, the algorithm’s noise resistance becomes more critical than ever for precise fundamental frequency estimation. Nonetheless, numerous state-of-the-art algorithms face struggles in achieving satisfying outcomes when confronted with speech recordings that are noisy with low signal-to-noise ratio (SNR) values. Also, most of the recent techniques utilize different frame lengths for pitch extraction. From this point of view, This research considers different frame lengths on male and female speech signals for fundamental frequency extraction. Also, analyze the frame length dependency on the speech signal analytically to understand which frame length is more suitable and effective for male and female speech signals specifically. For the validation of our idea, we have utilized the conventional autocorrelation function (ACF), and state-of-the-art method BaNa. This study puts out a potent idea that will work better for speech processing applications in noisy speech. From experimental results, the proposed idea represents which frame length is more appropriate for male and female speech signals in noisy environments.
文摘In the United States, the costs of health care have become a major burden for the health care system. In order to address this problem, the hospitals of Syracuse, New York, developed programs to provide subacute and complex care. The Subacute programs provided patient transportation services for dialysis and other types of care outside hospitals. They also developed programs for services such as intravenous therapy in nursing homes. The Complex Care Programs, such as intravenous therapy and mental health services, have provided alternatives to extended care in hospitals. During the past five years, utilization of these programs has varied, declining between 2019 and 2022, and then increasing between 2022 and 2024. The programs have avoided the need for 1530 - 2974 patient days in hospitals. The programs saved the Syracuse hospitals approximately $600 per inpatient day. This amounted to savings of $918,000 - $1,784,400 per year. These programs demonstrated how relatively small mechanisms can save large amounts of health care resources.
基金the Special Project of the National Science Foundation of China(NSFC)“Open Development of China’s Trade and Investment:Basic Patterns,Overall Effects,and the Dual Circulations Paradigm”(Grant No.72141309)NSFC General Project“GVC Restructuring Effect of Emergent Public Health Incidents:Based on the General Equilibrium Model Approach of the Production Networks Structure”(Grant No.72073142)+1 种基金NSFC General Project“China’s Industrialization Towards Mid-and High-End Value Chains:Theoretical Implications,Measurement and Analysis”(Grant No.71873142)the Youth project of The National Social Science Fund of China“Research on the green and low-carbon development path and policy optimization of China’s foreign trade under the goal of‘dual carbon’”(Grant No.22CJY019).
文摘Productivity and international energy price shocks are reflected in PPI and CPI via industrial chains.China’s in-depth participation into the global value chains has increasingly lengthened its industrial production chains.The question is how the changing length of production chains will affect CPI and PPI,as well as CPI-PPI correlation?By constructing a global input-output price model,this paper offers a theoretical discussion on the impact of production chain length on the CPI-PPI divergence.Our findings suggest that the price shock of international bulk commodities has a greater impact on China’s PPI than that on CPI.The effects on both China’s PPI and CPI estimated by using the single-country input-output model are higher than the results estimated with the global input-output model.However,the difference between CPI and PPI variations estimated with the global input-output model is greater than the result estimated with the single-country input-output model,which supports the view that the lengthening of production chains,especially international production chains,leads to a divergence between CPI and PPI.Empirical results based on cross-national panel data also suggest that the lengthening of production chains has reduced the CPI-PPI correlation for countries,i.e.the lengthening of production chains has increased the PPI-CPI divergence.That is to say,policymakers should target not just CPI in maintaining price stability,but instead focus on the stability of both PPI and CPI.Efforts can be made to proactively adjust the price index system,and formulate the industrial chain price index.
文摘Background: In-hospital mortality is a key indicator of the quality of care. Studies so far have demonstrated the influence of patient and hospital-related factors on in-hospital mortality. Currently, new variables, such as components of metabolic syndrome as comorbid conditions, are being incorporated as independent risk factors. We aimed to identify which individual, clinical and hospital characteristics are related to hospital mortality. Objectives: Demonstrate that the Cox proportional hazard model is not appropriate for the analysis of hospital mortality data when diagnostic-related groups are incorporated in the covariate structure. Methods: A retrospective single-center observational study design was used. Sampling was conducted between January 2016 and December 2018. Patients over 10 years, admitted to the emergency department with a precited stay of at least 1 hour were included. Multivariate Cox regression for survival data analyses was employed to analyze the data. Results: The sample consisted of 5897 patients. The mean age of all patients was 32.21 ± 0.29 years old, and the mean length of stay (LOS) was 9.47 ± 0.16 hours. We also categorized patients according to five Diagnosis Related Groups (DGR). Among the patients,1308 suffered from acute leukemia, 1127 had endocrine diseases, 1173 with kidney diseases, and 1016 had respiratory problems. At least one component of metabolic syndrome was present in 27.5% of the patients. During the observation period, 2299 (39%) died in hospital, and 3598 (61%) were discharged alive. We used the multivariate Cox regression non-proportional hazard model to evaluate the joint effect of these factors on the “Length of Stay” or LOS (the dependent variable of Cox regression). Age at admission, the presence of metabolic syndrome, and the DRG were significantly associated with the LOS.
