Rockbursts have become a significant hazard in underground mining,underscoring the need for a robust early warning model to ensure safety management.This study presents a novel approach for rockburst prediction,integr...Rockbursts have become a significant hazard in underground mining,underscoring the need for a robust early warning model to ensure safety management.This study presents a novel approach for rockburst prediction,integrating the Mann-Kendall trend test(MKT)and multi-indices fusion to enable real-time and quantitative assessment of rockburst hazards.The methodology employed in this study involves the development of a comprehensive precursory index library for rockbursts.The MKT is then applied to analyze the real-time trend of each index,with adherence to rockburst characterization laws serving as the warning criterion.By employing a confusion matrix,the warning effectiveness of each index is assessed,enabling index preference determination.Ultimately,the integrated rockburst hazard index Q is derived through data fusion.The results demonstrate that the proposed model achieves a warning effectiveness of 0.563 for Q,surpassing the performance of any individual index.Moreover,the model’s adaptability and scalability are enhanced through periodic updates driven by actual field monitoring data,making it suitable for complex underground working environments.By providing an efficient and accurate basis for decision-making,the proposed model holds great potential for the prevention and control of rockbursts.It offers a valuable tool for enhancing safety measures in underground mining operations.展开更多
Vegetation is the main component of the terrestrial ecosystem and plays a key role in global climate change. Remotely sensed vegetation indices are widely used to detect vegetation trends at large scales. To understan...Vegetation is the main component of the terrestrial ecosystem and plays a key role in global climate change. Remotely sensed vegetation indices are widely used to detect vegetation trends at large scales. To understand the trends of vegetation cover, this research examined the spatial-temporal trends of global vegetation by employing the normalized difference vegetation index(NDVI) from the Advanced Very High Resolution Radiometer(AVHRR) Global Inventory Modeling and Mapping Studies(GIMMS) time series(1982–2015). Ten samples were selected to test the temporal trend of NDVI, and the results show that in arid and semi-arid regions, NDVI showed a deceasing trend, while it showed a growing trend in other regions. Mann-Kendal(MK) trend test results indicate that 83.37% of NDVI pixels exhibited positive trends and that only 16.63% showed negative trends(P < 0.05) during the period from 1982 to 2015. The increasing NDVI trends primarily occurred in tree-covered regions because of forest growth and re-growth and also because of vegetation succession after a forest disturbance. The increasing trend of the NDVI in cropland regions was primarily because of the increasing cropland area and the improvement in planting techniques. This research describes the spatial vegetation trends at a global scale over the past 30+ years, especially for different land cover types.展开更多
Gemstones have fascinated mankind forever,and people traveled far to find them.The Silk Road is one of the most traditional trade routes in the middle ages that was used to bring the precious stones to the European ma...Gemstones have fascinated mankind forever,and people traveled far to find them.The Silk Road is one of the most traditional trade routes in the middle ages that was used to bring the precious stones to the European market.Later,emeralds from Colombia were shipped via the ocean to the Old World.展开更多
Rainfall expresses one of the most complex climate factors in Southeastern Brazil. Understanding the dynamics and temporal trends of rainfall represents a significant challenge due to regional and even global mechanis...Rainfall expresses one of the most complex climate factors in Southeastern Brazil. Understanding the dynamics and temporal trends of rainfall represents a significant challenge due to regional and even global mechanisms, such as FS (Frontal Systems) and the SACZ (South Atlantic Convergence Zone), and the interaction with the Atlantic and Pacific Oceans. The present study aimed at analyzing the pluviometric tendencies in S<span style="color:#4F4F4F;font-family:"font-size:14px;white-space:normal;background-color:#F7F7F7;">ã</span>o Carlos/SP, in the countryside of S<span style="color:#4F4F4F;font-family:"font-size:14px;white-space:normal;background-color:#F7F7F7;">ã</span>o Paulo State. Laplace trend test was used to comprehend the temporal evolution of daily rainfall in the region in the historical series 1979-2017, in seven pluviometric stations (climatological or surface stations). Significant fluctuations in interannual trends and between seasons were observed. However, it was noted that the beginning of the 1980s showed positive trends, whereas, as of the year 2000, most of the stations demonstrated negative trends, indicating a reduction in daily rainfall volume due to the great tropical climatic variability of Brazil. Emphasis should also be given to the regional and local effects, such as elevation and urbanization, respectively, which corroborate such differences among the analyzed stations. This methodology is of considerable value for the observation of pluviometric trends, and future studies can validate such a tool in climatological studies.展开更多
The impact trend of reck-coal system was studied by the method of accumulating and releasing of deformation energy and interaction of rock-coal system. The system model of roof-coal-floor was established. Based on the...The impact trend of reck-coal system was studied by the method of accumulating and releasing of deformation energy and interaction of rock-coal system. The system model of roof-coal-floor was established. Based on the RFPA software, rock fracture process analysis system, the numerical test of deformation, fracture and energy transmission of nonlinear and nonhomogeneous rock-coal system, and the numerical test and evaluating method of impact trend of reck-coal system were achieved. When the same coal seam was in different roof and floor conditions, the fracture process of reck-coal system can be classified as gradual, sudden and delayed fracture three kinds, and their impact trend can be classified as void, intense and medium correspondingly. The rock-coal system＇s impact trend is evaluated by the system impact index p and burst expanding forms. The criteria μ are μ〈1.0, 1.0≤μ〈l .5 and μ≥1.5 when the impact trend is void, intense or medium, which are tested and verified by the No.2 and No.4 coal seams in Sun- cun mine.展开更多
Rainfall and temperature variability analysis is important for researchers and policy formulators in making critical decisions on water availability and use in communities. The Western Sahel, which comprises Mali is c...Rainfall and temperature variability analysis is important for researchers and policy formulators in making critical decisions on water availability and use in communities. The Western Sahel, which comprises Mali is considered as one of the vulnerable regions to climate change, and also encountered the challenges of climatic shocks such as flood and drought. This research therefore sought to investigate climate change effects on hydrological events and trends in Sahelian rainfall intensity using Bamako (Mali) as a case study from 1991 to 2020, as limited data availability did not allow an extended period of study. Monthly observed data provided by MALI-METEO was used to validate daily rainfalls data from African Rainfall Climatology Version 2 (ARC2) satellite-based rainfall product on monthly basis. The validated model performance used Nash-Sutcliffe Efficiency (NSE) and Percent Bias (PBAIS) and gave results of 0.904 and 1.0506 respectively. Trends in annual maximum temperatures and rainfalls were analyzed using Mann-Kendall trend test. The result indicated that the trend in annual maximum rainfalls was decreasing, while annual total rainfall was increasing but not significant at 5% significance level. The rate of increase in annual total rainfalls was 0.475 mm/year according to the observed annual rainfall series and decreased to 0.68 mm/year in annual maximum. The analysis further found that annual maximum temperatures were increasing at the rate of 0.03°C/year at 5% significance level. To provide more accurate climate predictions, it is recommended that further studies on rainfall and temperature with data sets spanning 60 - 90 years be carried out.展开更多
Genetic association studies usually apply the simple chi-square (χ<sup>2</sup>)-test for testing association between a single-nucleotide polymorphism (SNP) and a particular phenotype, assuming the genotyp...Genetic association studies usually apply the simple chi-square (χ<sup>2</sup>)-test for testing association between a single-nucleotide polymorphism (SNP) and a particular phenotype, assuming the genotypes and phenotypes are independent. So, the conventional χ<sup>2</sup>-test does not consider the increased risk of an individual carrying the increasing number of disease responsible allele (a particular genotype). But, the association tests should be performed with the consideration of this disease risk according to the mode of inheritance (additive, dominant, recessive). Practical demonstration of the two possible methods for considering such order or trends in contingency tables of genetic association studies using SNP genotype data is the purpose of this paper. One method is by pooling the genotypes, and the other is scoring the individual genotypes, based on the disease risk according to the inheritance pattern. The results show that the p-values obtained from both the methods are similar for the dominant and recessive models. The other important features of the methods were also extracted using the SNP genotype data for different inheritance patterns.展开更多
Communicative testing, with its purpose of measuring communicative competence, has brought changes to the current EFL tests in content and format and produced a widespread and profound influence on modern language tes...Communicative testing, with its purpose of measuring communicative competence, has brought changes to the current EFL tests in content and format and produced a widespread and profound influence on modern language testing models in the two decades. This paper gives a brief introduction to the development of communicative testing, and presents the trend of modern EFL testing in the aspects of oral test, proportion of subjective and objective items, content, context, incorporation of skills as well as criteria of assessment, which is the result of enlightenment of communicative testing theories.展开更多
Objective:This study aims to analyze how changes in pathological diagnosis practice and molecular detection technology have affected clinical outcomes for colorectal cancer(CRC)patients in Hehai University Shanghai Ca...Objective:This study aims to analyze how changes in pathological diagnosis practice and molecular detection technology have affected clinical outcomes for colorectal cancer(CRC)patients in Hehai University Shanghai Cancer Center(FUSCC).Methods:This retrospective cohort study analyzed 21,141 pathologically confirmed CRC cases diagnosed at FUSCC from 2008 to 2020.Patients were divided into five groups for different analytical purposes:(1)the before vs.since 2014 groups to analyze the influence of the changes in the classification criteria of pT3 and pT4 staging on the survival of patients;(2)the partial vs.total mesorectal excision(TME)groups to analyze whether evaluation of completeness of the mesorectum have impact on the survival of patients;(3)the tumor deposit(TD)(+)N0 vs.TD(+)N1c groups to analyze the influence of the changes in the pN staging on the survival of patients with positive TD and negative regional lymph node metastasis(LNM);(4)the before vs.since 2013 groups to analyze the influence of the changes in the testing process of deficient mismatch repair on the survival of patients;and(5)the groups with vs.without RAS/BRAF gene mutation testing to analyze the influence of these testing on the survival of patients.Patients’clinicopathological parameters,including age at diagnosis,sex,tumor size,location,differentiation,mucinous subtype,TD,lymphovascular invasion,perineural invasion,tumor depth,LNM and distant metastasis,and tumor-node-metastasis(TNM)stage,were compared between groups.Kaplan-Meier analysis with log rank method was performed for patients’overall survival(OS)and disease-free survival(DFS)analyses.Results:In pathological reports,there were three parameter changes that impacted patient outcomes.Firstly,changes in the pT staging criteria led to a shift of the ratio of patients with stage pT3 to stage pT4 from 1:110.9 to 1:0.26.In comparison to patients admitted before 2014(n=4,754),a significant difference in prognosis between pT3 and pT4 stages was observed since 2014(n=9,965).Secondly,we began to evaluate the completeness of the mesorectum since 2016.As a result,91.0%of patients with low rectal cancer underwent TME(n=4,111)surgery,and patients with TME had significantly better OS compared with partial mesorectal excision(PME,n=409).Thirdly,we began to stage TD(+)LNM(-)as N1c since 2017.The results showed that N1c(n=127)but not N0(n=39)can improve the prognosis of patients without LNM and distal metastasis.In molecular testing,there have been three and five iterations of updates regarding mismatch repair(MMR)/microsatellite instability(MSI)status and RAS/BRAF gene mutation detection,respectively.The standardization of MMR status testing has sharply decreased the proportion of deficient MMR(dMMR)patients(from 32.5%to 7.4%)since 2013.The prognosis of patients underwent MMR status testing since 2013(n=867)were significantly better than patients before 2013(n=1,313).In addition,detection of RAS/BRAF gene mutation status(n=5,041)resulted in better DFS but not OS,for patients with stage I-III disease(n=16,557).Conclusion:Over the past few decades,updates in elements in pathological reports,as well as the development of standardized tests for MMR/MSI status and RAS/BRAF gene mutations have significantly improved patient outcomes.展开更多
基金The authors gratefully acknowledge the financial support from the National Natural Science Foundation of China(Grant Nos.52011530037 and 51904019)the Fundamental Research Funds for the Central Universities and the Youth Teacher International Exchange&Growth Program(Grant No.QNXM20210004).We also greatly appreciate the assistance provided by Kuangou coal mine,China Energy Group Xinjiang Energy Co.,Ltd.
文摘Rockbursts have become a significant hazard in underground mining,underscoring the need for a robust early warning model to ensure safety management.This study presents a novel approach for rockburst prediction,integrating the Mann-Kendall trend test(MKT)and multi-indices fusion to enable real-time and quantitative assessment of rockburst hazards.The methodology employed in this study involves the development of a comprehensive precursory index library for rockbursts.The MKT is then applied to analyze the real-time trend of each index,with adherence to rockburst characterization laws serving as the warning criterion.By employing a confusion matrix,the warning effectiveness of each index is assessed,enabling index preference determination.Ultimately,the integrated rockburst hazard index Q is derived through data fusion.The results demonstrate that the proposed model achieves a warning effectiveness of 0.563 for Q,surpassing the performance of any individual index.Moreover,the model’s adaptability and scalability are enhanced through periodic updates driven by actual field monitoring data,making it suitable for complex underground working environments.By providing an efficient and accurate basis for decision-making,the proposed model holds great potential for the prevention and control of rockbursts.It offers a valuable tool for enhancing safety measures in underground mining operations.
基金Under the auspices of National Natural Science Foundation of China(No.41771179,41871103,41771138)the National Key Research and Development Project(No.2016YFA0602301)
文摘Vegetation is the main component of the terrestrial ecosystem and plays a key role in global climate change. Remotely sensed vegetation indices are widely used to detect vegetation trends at large scales. To understand the trends of vegetation cover, this research examined the spatial-temporal trends of global vegetation by employing the normalized difference vegetation index(NDVI) from the Advanced Very High Resolution Radiometer(AVHRR) Global Inventory Modeling and Mapping Studies(GIMMS) time series(1982–2015). Ten samples were selected to test the temporal trend of NDVI, and the results show that in arid and semi-arid regions, NDVI showed a deceasing trend, while it showed a growing trend in other regions. Mann-Kendal(MK) trend test results indicate that 83.37% of NDVI pixels exhibited positive trends and that only 16.63% showed negative trends(P < 0.05) during the period from 1982 to 2015. The increasing NDVI trends primarily occurred in tree-covered regions because of forest growth and re-growth and also because of vegetation succession after a forest disturbance. The increasing trend of the NDVI in cropland regions was primarily because of the increasing cropland area and the improvement in planting techniques. This research describes the spatial vegetation trends at a global scale over the past 30+ years, especially for different land cover types.
文摘Gemstones have fascinated mankind forever,and people traveled far to find them.The Silk Road is one of the most traditional trade routes in the middle ages that was used to bring the precious stones to the European market.Later,emeralds from Colombia were shipped via the ocean to the Old World.
文摘Rainfall expresses one of the most complex climate factors in Southeastern Brazil. Understanding the dynamics and temporal trends of rainfall represents a significant challenge due to regional and even global mechanisms, such as FS (Frontal Systems) and the SACZ (South Atlantic Convergence Zone), and the interaction with the Atlantic and Pacific Oceans. The present study aimed at analyzing the pluviometric tendencies in S<span style="color:#4F4F4F;font-family:"font-size:14px;white-space:normal;background-color:#F7F7F7;">ã</span>o Carlos/SP, in the countryside of S<span style="color:#4F4F4F;font-family:"font-size:14px;white-space:normal;background-color:#F7F7F7;">ã</span>o Paulo State. Laplace trend test was used to comprehend the temporal evolution of daily rainfall in the region in the historical series 1979-2017, in seven pluviometric stations (climatological or surface stations). Significant fluctuations in interannual trends and between seasons were observed. However, it was noted that the beginning of the 1980s showed positive trends, whereas, as of the year 2000, most of the stations demonstrated negative trends, indicating a reduction in daily rainfall volume due to the great tropical climatic variability of Brazil. Emphasis should also be given to the regional and local effects, such as elevation and urbanization, respectively, which corroborate such differences among the analyzed stations. This methodology is of considerable value for the observation of pluviometric trends, and future studies can validate such a tool in climatological studies.
基金the Ministry of Education Backbone Teachers Funded Projects
文摘The impact trend of reck-coal system was studied by the method of accumulating and releasing of deformation energy and interaction of rock-coal system. The system model of roof-coal-floor was established. Based on the RFPA software, rock fracture process analysis system, the numerical test of deformation, fracture and energy transmission of nonlinear and nonhomogeneous rock-coal system, and the numerical test and evaluating method of impact trend of reck-coal system were achieved. When the same coal seam was in different roof and floor conditions, the fracture process of reck-coal system can be classified as gradual, sudden and delayed fracture three kinds, and their impact trend can be classified as void, intense and medium correspondingly. The rock-coal system＇s impact trend is evaluated by the system impact index p and burst expanding forms. The criteria μ are μ〈1.0, 1.0≤μ〈l .5 and μ≥1.5 when the impact trend is void, intense or medium, which are tested and verified by the No.2 and No.4 coal seams in Sun- cun mine.
文摘Rainfall and temperature variability analysis is important for researchers and policy formulators in making critical decisions on water availability and use in communities. The Western Sahel, which comprises Mali is considered as one of the vulnerable regions to climate change, and also encountered the challenges of climatic shocks such as flood and drought. This research therefore sought to investigate climate change effects on hydrological events and trends in Sahelian rainfall intensity using Bamako (Mali) as a case study from 1991 to 2020, as limited data availability did not allow an extended period of study. Monthly observed data provided by MALI-METEO was used to validate daily rainfalls data from African Rainfall Climatology Version 2 (ARC2) satellite-based rainfall product on monthly basis. The validated model performance used Nash-Sutcliffe Efficiency (NSE) and Percent Bias (PBAIS) and gave results of 0.904 and 1.0506 respectively. Trends in annual maximum temperatures and rainfalls were analyzed using Mann-Kendall trend test. The result indicated that the trend in annual maximum rainfalls was decreasing, while annual total rainfall was increasing but not significant at 5% significance level. The rate of increase in annual total rainfalls was 0.475 mm/year according to the observed annual rainfall series and decreased to 0.68 mm/year in annual maximum. The analysis further found that annual maximum temperatures were increasing at the rate of 0.03°C/year at 5% significance level. To provide more accurate climate predictions, it is recommended that further studies on rainfall and temperature with data sets spanning 60 - 90 years be carried out.
文摘Genetic association studies usually apply the simple chi-square (χ<sup>2</sup>)-test for testing association between a single-nucleotide polymorphism (SNP) and a particular phenotype, assuming the genotypes and phenotypes are independent. So, the conventional χ<sup>2</sup>-test does not consider the increased risk of an individual carrying the increasing number of disease responsible allele (a particular genotype). But, the association tests should be performed with the consideration of this disease risk according to the mode of inheritance (additive, dominant, recessive). Practical demonstration of the two possible methods for considering such order or trends in contingency tables of genetic association studies using SNP genotype data is the purpose of this paper. One method is by pooling the genotypes, and the other is scoring the individual genotypes, based on the disease risk according to the inheritance pattern. The results show that the p-values obtained from both the methods are similar for the dominant and recessive models. The other important features of the methods were also extracted using the SNP genotype data for different inheritance patterns.
文摘Communicative testing, with its purpose of measuring communicative competence, has brought changes to the current EFL tests in content and format and produced a widespread and profound influence on modern language testing models in the two decades. This paper gives a brief introduction to the development of communicative testing, and presents the trend of modern EFL testing in the aspects of oral test, proportion of subjective and objective items, content, context, incorporation of skills as well as criteria of assessment, which is the result of enlightenment of communicative testing theories.
基金supported by National Natural Science Foundation of China(grant numbers:82273370,82202899,82172702,81972249,81902430,82002543,82002946,U1932145)Shanghai Clinical Science and Technology Innovation Project of Municipal Hospital(grant number:SHDC12020102)+5 种基金Natural Science Foundation of Shanghai(grant numbers:22ZR1413000,21ZR1414900)Artificial Intelligence Medical Hospital Cooperation Project of Xuhui District(grant number:2021-017)Shanghai Science and Technology Development Fund(grant number:19MC1911000)Shanghai Municipal Key Clinical Specialty(grant number:shslczdzk01301)Science and Technology Commission of Shanghai Municipality(grant number:18401933402)“Chenguang Program”supported by Shanghai Education Development Foundation and Shanghai Municipal Education Commission(grant number:20CG08).
文摘Objective:This study aims to analyze how changes in pathological diagnosis practice and molecular detection technology have affected clinical outcomes for colorectal cancer(CRC)patients in Hehai University Shanghai Cancer Center(FUSCC).Methods:This retrospective cohort study analyzed 21,141 pathologically confirmed CRC cases diagnosed at FUSCC from 2008 to 2020.Patients were divided into five groups for different analytical purposes:(1)the before vs.since 2014 groups to analyze the influence of the changes in the classification criteria of pT3 and pT4 staging on the survival of patients;(2)the partial vs.total mesorectal excision(TME)groups to analyze whether evaluation of completeness of the mesorectum have impact on the survival of patients;(3)the tumor deposit(TD)(+)N0 vs.TD(+)N1c groups to analyze the influence of the changes in the pN staging on the survival of patients with positive TD and negative regional lymph node metastasis(LNM);(4)the before vs.since 2013 groups to analyze the influence of the changes in the testing process of deficient mismatch repair on the survival of patients;and(5)the groups with vs.without RAS/BRAF gene mutation testing to analyze the influence of these testing on the survival of patients.Patients’clinicopathological parameters,including age at diagnosis,sex,tumor size,location,differentiation,mucinous subtype,TD,lymphovascular invasion,perineural invasion,tumor depth,LNM and distant metastasis,and tumor-node-metastasis(TNM)stage,were compared between groups.Kaplan-Meier analysis with log rank method was performed for patients’overall survival(OS)and disease-free survival(DFS)analyses.Results:In pathological reports,there were three parameter changes that impacted patient outcomes.Firstly,changes in the pT staging criteria led to a shift of the ratio of patients with stage pT3 to stage pT4 from 1:110.9 to 1:0.26.In comparison to patients admitted before 2014(n=4,754),a significant difference in prognosis between pT3 and pT4 stages was observed since 2014(n=9,965).Secondly,we began to evaluate the completeness of the mesorectum since 2016.As a result,91.0%of patients with low rectal cancer underwent TME(n=4,111)surgery,and patients with TME had significantly better OS compared with partial mesorectal excision(PME,n=409).Thirdly,we began to stage TD(+)LNM(-)as N1c since 2017.The results showed that N1c(n=127)but not N0(n=39)can improve the prognosis of patients without LNM and distal metastasis.In molecular testing,there have been three and five iterations of updates regarding mismatch repair(MMR)/microsatellite instability(MSI)status and RAS/BRAF gene mutation detection,respectively.The standardization of MMR status testing has sharply decreased the proportion of deficient MMR(dMMR)patients(from 32.5%to 7.4%)since 2013.The prognosis of patients underwent MMR status testing since 2013(n=867)were significantly better than patients before 2013(n=1,313).In addition,detection of RAS/BRAF gene mutation status(n=5,041)resulted in better DFS but not OS,for patients with stage I-III disease(n=16,557).Conclusion:Over the past few decades,updates in elements in pathological reports,as well as the development of standardized tests for MMR/MSI status and RAS/BRAF gene mutations have significantly improved patient outcomes.
