Classical localization methods use Cartesian or Polar coordinates, which require a priori range information to determine whether to estimate position or to only find bearings. The modified polar representation (MPR) u...Classical localization methods use Cartesian or Polar coordinates, which require a priori range information to determine whether to estimate position or to only find bearings. The modified polar representation (MPR) unifies near-field and farfield models, alleviating the thresholding effect. Current localization methods in MPR based on the angle of arrival (AOA) and time difference of arrival (TDOA) measurements resort to semidefinite relaxation (SDR) and Gauss-Newton iteration, which are computationally complex and face the possible diverge problem. This paper formulates a pseudo linear equation between the measurements and the unknown MPR position,which leads to a closed-form solution for the hybrid TDOA-AOA localization problem, namely hybrid constrained optimization(HCO). HCO attains Cramér-Rao bound (CRB)-level accuracy for mild Gaussian noise. Compared with the existing closed-form solutions for the hybrid TDOA-AOA case, HCO provides comparable performance to the hybrid generalized trust region subproblem (HGTRS) solution and is better than the hybrid successive unconstrained minimization (HSUM) solution in large noise region. Its computational complexity is lower than that of HGTRS. Simulations validate the performance of HCO achieves the CRB that the maximum likelihood estimator (MLE) attains if the noise is small, but the MLE deviates from CRB earlier.展开更多
Considering three longitudinal displacement functions and uniform axial displacement functions for shear lag effect and uniform axial deformation of thin-walled box girder with varying depths,a simple and efficient me...Considering three longitudinal displacement functions and uniform axial displacement functions for shear lag effect and uniform axial deformation of thin-walled box girder with varying depths,a simple and efficient method with high precision to analyze the shear lag effect of thin-walled box girders was proposed.The governing differential equations and boundary conditions of the box girder under lateral loading were derived based on the energy-variational method,and closed-form solutions to stress and deflection corresponding to lateral loading were obtained.Analysis and calculations were carried out with respect to a trapezoidal box girder under concentrated loading or uniform loading and a rectangular box girder under concentrated loading.The analytical results were compared with numerical solutions derived according to the high order finite strip element method and the experimental results.The investigation shows that the closed-form solution is in good agreement with the numerical solutions derived according to the high order finite strip method and the experimental results,and has good stability.Because of the shear lag effect,the stress in cross-section centroid is no longer zero,thus it is not reasonable enough to assume that the strain in cross-section centroid is zero without considering uniform axial deformation.展开更多
Based on the consideration of longitudinal warp caused by shear lag effects on concrete slabs and bottom plates of steel beams,shear deformation of steel beams and interface slip between steel beams and concrete slabs...Based on the consideration of longitudinal warp caused by shear lag effects on concrete slabs and bottom plates of steel beams,shear deformation of steel beams and interface slip between steel beams and concrete slabs,the governing differential equations and boundary conditions of the steel-concrete composite box beams under lateral loading were derived using energy-variational method.The closed-form solutions for stress,deflection and slip of box beams under lateral loading were obtained,and the comparison of the analytical results and the experimental results for steel-concrete composite box beams under concentrated loading or uniform loading verifies the closed-form solution.The investigation of the parameters of load effects on composite box beams shows that:1) Slip stiffness has considerable impact on mid-span deflection and end slip when it is comparatively small;the mid-span deflection and end slip decrease significantly with the increase of slip stiffness,but when the slip stiffness reaches a certain value,its impact on mid-span deflection and end slip decreases to be negligible.2) The shear deformation has certain influence on mid-span deflection,and the larger the load is,the greater the influence is.3) The impact of shear deformation on end slip can be neglected.4) The strain of bottom plate of steel beam decreases with the increase of slip stiffness,while the shear lag effect becomes more significant.展开更多
The direct separation of variables is used to obtain the closed-form solutions for the free vibrations of rectangular Mindlin plates. Three different characteristic equations are derived by using three different metho...The direct separation of variables is used to obtain the closed-form solutions for the free vibrations of rectangular Mindlin plates. Three different characteristic equations are derived by using three different methods. It is found that the deflection can be expressed by means of the four characteristic roots and the two rotations should be expressed by all the six characteristic roots,which is the particularity of Mindlin plate theory. And the closed-form solutions,which satisfy two of the three governing equations and all boundary conditions and are accurate for rectangular plates with moderate thickness,are derived for any combinations of simply supported and clamped edges. The free edges can also be dealt with if the other pair of opposite edges is simply supported. The present results agree well with results published previously by other methods for different aspect ratios and relative thickness.展开更多
In this paper,a nonlinear strength criterion is proposed using the average of intermediate(σ2)and minor(σ3)principal stresses in place of σ3 in Ramamurthy(1994)’s strength criterion.The proposed criterion has the ...In this paper,a nonlinear strength criterion is proposed using the average of intermediate(σ2)and minor(σ3)principal stresses in place of σ3 in Ramamurthy(1994)’s strength criterion.The proposed criterion has the main advantages of negligible variation of strength parameters with confining stress and ability to link with conventional strength parameters.Additionally,a new closed-form solution based on the proposed criterion is derived and validated for Chhibro Khodri tunnel.Further,analytical solutions including Singh’s elastoplastic theory,Scussel’s approach,and closed-form solutions based on conventional and modified Ramamurthy(2007)criteria are compared with the results of proposed approach.It is shown that the in situ squeezing pressure predictions made by the proposed approach are more accurate.Also,a parametric study of the present analytical solution is carried out,which displays explicit dependency of tunnel stability on internal support pressure and tunnel depth.The influence of tunnel geometry is observed to be dependent on the applied support pressure.展开更多
In this paper,an exact closed-form solution for a curved sandwich panel with two piezoelectric layers as actuator and sensor that are inserted in the top and bottom facings is presented.The core is made from functiona...In this paper,an exact closed-form solution for a curved sandwich panel with two piezoelectric layers as actuator and sensor that are inserted in the top and bottom facings is presented.The core is made from functionally graded(FG)material that has heterogeneous power-law distribution through the radial coordinate.It is assumed that the core is subjected to a magnetic field whereas the core is covered by two insulated composite layers.To determine the exact solution,first characteristic equations are derived for different material types in a polar coordinate system,namely,magneto-elastic,elastic,and electro-elastic for the FG,orthotropic,and piezoelectric materials,respectively.The displacement-based method is used instead of the stress-based method to derive a set of closed-form real-valued solutions for both real and complex roots.Based on the elasticity theory,exact solutions for the governing equations are determined layer-by-layer that are considerably more accurate than typical simplified theories.The accuracy of the presented method is compared and validated with the available literature and the finite element simulation.The effects of geometrical and material parameters such as FG index,angular span along with external conditions such as magnetic field,mechanical pressure,and electrical difference are investigated in detail through numerical examples.展开更多
Density-graded cellular materials have tremendous potential in structural applications where impact resistance is required.Cellular materials subjected to high impact loading result in a compaction type deformation,us...Density-graded cellular materials have tremendous potential in structural applications where impact resistance is required.Cellular materials subjected to high impact loading result in a compaction type deformation,usually modeled using continuum-based shock theory.The resulting governing differential equation of the shock model is nonlinear,and the density gradient further complicates the problem.Earlier studies have employed numerical methods to obtain the solution.In this study,an analytical closed-form solution is proposed to predict the response of density-graded cellular materials subjected to a rigid body impact.Solutions for the velocity of the impinging rigid body mass,energy absorption capacity of the cellular material,and the incident stress are obtained for a single shock propagation.The results obtained are in excellent agreement with the existing numerical solutions found in the literature.The proposed analytical solution can be potentially used for parametric studies and for effectively designing graded structures to mitigate impact.展开更多
A closed-form solution to the linear matrix equation AX-EXF = BY with X and Y unknown and matrix F being in a companion form is proposed, and two equivalent forms of this solution are also presented. The results provi...A closed-form solution to the linear matrix equation AX-EXF = BY with X and Y unknown and matrix F being in a companion form is proposed, and two equivalent forms of this solution are also presented. The results provide great convenience to the computation and analysis of the solutions to this class of equations, and can perform important functions in many analysis and design problems in descriptor system theory. The results proposed here are parallel to and more general than our early work about the linear matrix equation AX-XF = BY .展开更多
Efficient calculation of the electrostatic interactions including repulsive force between charged molecules in a biomolecule system or charged particles in a colloidal system is necessary for the molecular scale or pa...Efficient calculation of the electrostatic interactions including repulsive force between charged molecules in a biomolecule system or charged particles in a colloidal system is necessary for the molecular scale or particle scale mechanical analyses of these systems. The electrostatic repulsive force depends on the mid-plane potential between two charged particles. Previous analytical solutions of the mid-plane potential, including those based on simplified assumptions and modern mathematic methods, are reviewed. It is shown that none of these solutions applies to wide ranges of interparticle distance from 0 to 10 and surface potential from 1 to 10. Three previous analytical solutions are chosen to develop a semi-analytical solution which is proven to have more extensive applications. Furthermore, an empirical closed-form expression of mid-plane potential is proposed based on plenty of numerical solutions. This empirical solution has extensive applications, as well as high computational efficiency.展开更多
This article presents closed-form solutions for the frequency analysis of rectangular functionally graded material (FGM) thin plates subjected to initially in-plane loads and with an elastic foundation. Based on class...This article presents closed-form solutions for the frequency analysis of rectangular functionally graded material (FGM) thin plates subjected to initially in-plane loads and with an elastic foundation. Based on classical thin plate theory, the governing differential equations are derived using Hamilton's principle. A neutral surface is used to eliminate stretching-bending coupling in FGM plates on the basis of the assumption of constant Poisson's ratio. The resulting governing equation of FGM thin plates has the same form as homogeneous thin plates. The separation-of-variables method is adopted to obtain solutions for the free vibration problems of rectangular FGM thin plates with separable boundary conditions, including, for example, clamped plates. The obtained normal modes and frequencies are in elegant closed forms, and present formulations and solutions are validated by comparing present results with those in the literature and finite element method results obtained by the authors. A parameter study reveals the effects of the power law index n and aspect ratio a/b on frequencies.展开更多
Based on the integral equation formulations and the moment method, a novel closed form solution for analyzing the mutual coupling effect between the cylindrical comformal rectangular microstrip patch antennas is pres...Based on the integral equation formulations and the moment method, a novel closed form solution for analyzing the mutual coupling effect between the cylindrical comformal rectangular microstrip patch antennas is presented. By using this algorithm, the elements of the impedance matrix and exciting vector are cast into closed forms, thus the computational efficiency is improved dramatically. Numerical results are presented to verify the validity and reliability of the algorithm.展开更多
Dynamic programming(DP)is frequently used to obtain the optimal solution to the hybrid electric vehicle(HEV)energy management.The trade-off between the accuracy and the computational effort is the biggest problem for ...Dynamic programming(DP)is frequently used to obtain the optimal solution to the hybrid electric vehicle(HEV)energy management.The trade-off between the accuracy and the computational effort is the biggest problem for the DP method.The closed-form solution to the DP is proposed to solve this problem.Firstly,the affine linear model of the engine fuel rate is obtained based on engine test data.The piecewise linear approximation of the motor power demand is obtained considering the different energy flows in the charging and discharging stages of the battery.Then,the second-order Taylor expansion for the cost matrix at each time and state grid point is introduced to get the closed-form solution of the optimal torque split.The results show that this method can greatly reduce the computing burden by 93%while ensuring near-optimal fuel economy compared with the conventional DP method.展开更多
BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD....BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.展开更多
In this paper,we mainly focus on a type of nonlinear Choquard equations with nonconstant potential.Under appropriate hypotheses on potential function and nonlinear terms,we prove that the above Choquard equation with ...In this paper,we mainly focus on a type of nonlinear Choquard equations with nonconstant potential.Under appropriate hypotheses on potential function and nonlinear terms,we prove that the above Choquard equation with prescribed 2-norm has some normalized solutions by introducing variational methods.展开更多
In previous papers, we proposed the important Ztransformations and obtained general solutions to a large number of linear and quasi-linear partial differential equations for the first time. In this paper, we will use ...In previous papers, we proposed the important Ztransformations and obtained general solutions to a large number of linear and quasi-linear partial differential equations for the first time. In this paper, we will use the Z1transformation to get the general solutions of some nonlinear partial differential equations for the first time, and use the general solutions to obtain the exact solutions of some typical definite solution problems.展开更多
In this paper, we get the N-fold Darboux transformation with multi-parameters for the coupled mKdV equations with the help of a guage transformation of the spectral problem. As an application, some new multi-soliton s...In this paper, we get the N-fold Darboux transformation with multi-parameters for the coupled mKdV equations with the help of a guage transformation of the spectral problem. As an application, some new multi-soliton solutions and complexiton solutions are obtained from choosing the appropriate seed solution. All obtained solutions and N-fold Darboux transformations are expressed using the Vandermonde-like determinants.展开更多
This work focuses on a Keller-Segel chemotaxis model, with an emphasis on its conservation laws. Through a new approach combined with the multiplier method, called the mixed method, we obtain conservation vectors that...This work focuses on a Keller-Segel chemotaxis model, with an emphasis on its conservation laws. Through a new approach combined with the multiplier method, called the mixed method, we obtain conservation vectors that are related and unrelated to symmetric information. In addition, some exact solutions with particular forms are obtained according to the method of conservation laws. These particular solutions are different from the group-invariant solutions.展开更多
In this short paper, we first establish the existence of periodic solutions to parabolic equation in the whole space by using the probability method. Then, the periodicity of some function of stochastic process is als...In this short paper, we first establish the existence of periodic solutions to parabolic equation in the whole space by using the probability method. Then, the periodicity of some function of stochastic process is also studied.展开更多
The N-periodic wave solvability problem for the N=1 supersymmetric Sawada–Kotera–Ramani equation is considered by combining the Hirota's bilinear method and the super Riemann theta function. The constraint equat...The N-periodic wave solvability problem for the N=1 supersymmetric Sawada–Kotera–Ramani equation is considered by combining the Hirota's bilinear method and the super Riemann theta function. The constraint equations and unknown parameters are redefined, and the numerical calculation process of the N-periodic wave solutions is derived. It has been verified that under certain conditions, the asymptotic relations between N-periodic wave solutions and N-soliton solutions can be established. Some numerical solutions of three-periodic wave are presented. Under the influence of the Grassmann variable, the three-periodic wave solutions will generate an influence band in the middle region, and the amplitude becomes bigger as the distance from the influence band increases.展开更多
Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhan...Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhancing patient prognosis.Obviously,non-participation of asymptomatic individuals in screening programs hampers early diagnosis and may adversely affect long-term outcomes for CRC patients.In this letter,we provide a comprehensive overview of the current status of early screening practices,while also thoroughly examine the dilemmas and potential solutions associated with early screening for CRC.In response to these issues,we proffer a set of recommendations directed at governmental authorities and the general public,which focus on augmenting financial investment,establishing standardized screening protocols,advancing technological capabilities,and bolstering public awareness campaigns.The importance of collaborative efforts from various stakeholders cannot be overstated in the quest to enhance early detection rates and alleviate the societal burden of CRC.展开更多
基金supported by the National Natural Science Foundation of China (62101359)Sichuan University and Yibin Municipal People’s Government University and City Strategic Cooperation Special Fund Project (2020CDYB-29)+1 种基金the Science and Technology Plan Transfer Payment Project of Sichuan Province (2021ZYSF007)the Key Research and Development Program of Science and Technology Department of Sichuan Province (2020YFS0575,2021KJT0012-2 021YFS-0067)。
文摘Classical localization methods use Cartesian or Polar coordinates, which require a priori range information to determine whether to estimate position or to only find bearings. The modified polar representation (MPR) unifies near-field and farfield models, alleviating the thresholding effect. Current localization methods in MPR based on the angle of arrival (AOA) and time difference of arrival (TDOA) measurements resort to semidefinite relaxation (SDR) and Gauss-Newton iteration, which are computationally complex and face the possible diverge problem. This paper formulates a pseudo linear equation between the measurements and the unknown MPR position,which leads to a closed-form solution for the hybrid TDOA-AOA localization problem, namely hybrid constrained optimization(HCO). HCO attains Cramér-Rao bound (CRB)-level accuracy for mild Gaussian noise. Compared with the existing closed-form solutions for the hybrid TDOA-AOA case, HCO provides comparable performance to the hybrid generalized trust region subproblem (HGTRS) solution and is better than the hybrid successive unconstrained minimization (HSUM) solution in large noise region. Its computational complexity is lower than that of HGTRS. Simulations validate the performance of HCO achieves the CRB that the maximum likelihood estimator (MLE) attains if the noise is small, but the MLE deviates from CRB earlier.
基金Projects(51078355,50938008) supported by the National Natural Science Foundation of ChinaProject(CX2011B093) supported by the Doctoral Candidate Research Innovation Program of Hunan Province, ChinaProject(20117Q008) supported by the Basic Scientific Research Funds for Central Universities of China
文摘Considering three longitudinal displacement functions and uniform axial displacement functions for shear lag effect and uniform axial deformation of thin-walled box girder with varying depths,a simple and efficient method with high precision to analyze the shear lag effect of thin-walled box girders was proposed.The governing differential equations and boundary conditions of the box girder under lateral loading were derived based on the energy-variational method,and closed-form solutions to stress and deflection corresponding to lateral loading were obtained.Analysis and calculations were carried out with respect to a trapezoidal box girder under concentrated loading or uniform loading and a rectangular box girder under concentrated loading.The analytical results were compared with numerical solutions derived according to the high order finite strip element method and the experimental results.The investigation shows that the closed-form solution is in good agreement with the numerical solutions derived according to the high order finite strip method and the experimental results,and has good stability.Because of the shear lag effect,the stress in cross-section centroid is no longer zero,thus it is not reasonable enough to assume that the strain in cross-section centroid is zero without considering uniform axial deformation.
基金Projects(51078355,50938008) supported by the National Natural Science Foundation of ChinaProject(094801020) supported by the Academic Scholarship for Doctoral Candidates of the Ministry of Education,China+1 种基金Project(CX2011B093) supported by the Doctoral Candidate Research Innovation Project of Hunan Province, ChinaProject(20117Q008) supported by the Central University Basic Scientific Research Business Expenses Special Fund of China
文摘Based on the consideration of longitudinal warp caused by shear lag effects on concrete slabs and bottom plates of steel beams,shear deformation of steel beams and interface slip between steel beams and concrete slabs,the governing differential equations and boundary conditions of the steel-concrete composite box beams under lateral loading were derived using energy-variational method.The closed-form solutions for stress,deflection and slip of box beams under lateral loading were obtained,and the comparison of the analytical results and the experimental results for steel-concrete composite box beams under concentrated loading or uniform loading verifies the closed-form solution.The investigation of the parameters of load effects on composite box beams shows that:1) Slip stiffness has considerable impact on mid-span deflection and end slip when it is comparatively small;the mid-span deflection and end slip decrease significantly with the increase of slip stiffness,but when the slip stiffness reaches a certain value,its impact on mid-span deflection and end slip decreases to be negligible.2) The shear deformation has certain influence on mid-span deflection,and the larger the load is,the greater the influence is.3) The impact of shear deformation on end slip can be neglected.4) The strain of bottom plate of steel beam decreases with the increase of slip stiffness,while the shear lag effect becomes more significant.
基金supported by the National Natural Science Foundation of China (No. 10772014)
文摘The direct separation of variables is used to obtain the closed-form solutions for the free vibrations of rectangular Mindlin plates. Three different characteristic equations are derived by using three different methods. It is found that the deflection can be expressed by means of the four characteristic roots and the two rotations should be expressed by all the six characteristic roots,which is the particularity of Mindlin plate theory. And the closed-form solutions,which satisfy two of the three governing equations and all boundary conditions and are accurate for rectangular plates with moderate thickness,are derived for any combinations of simply supported and clamped edges. The free edges can also be dealt with if the other pair of opposite edges is simply supported. The present results agree well with results published previously by other methods for different aspect ratios and relative thickness.
文摘In this paper,a nonlinear strength criterion is proposed using the average of intermediate(σ2)and minor(σ3)principal stresses in place of σ3 in Ramamurthy(1994)’s strength criterion.The proposed criterion has the main advantages of negligible variation of strength parameters with confining stress and ability to link with conventional strength parameters.Additionally,a new closed-form solution based on the proposed criterion is derived and validated for Chhibro Khodri tunnel.Further,analytical solutions including Singh’s elastoplastic theory,Scussel’s approach,and closed-form solutions based on conventional and modified Ramamurthy(2007)criteria are compared with the results of proposed approach.It is shown that the in situ squeezing pressure predictions made by the proposed approach are more accurate.Also,a parametric study of the present analytical solution is carried out,which displays explicit dependency of tunnel stability on internal support pressure and tunnel depth.The influence of tunnel geometry is observed to be dependent on the applied support pressure.
文摘In this paper,an exact closed-form solution for a curved sandwich panel with two piezoelectric layers as actuator and sensor that are inserted in the top and bottom facings is presented.The core is made from functionally graded(FG)material that has heterogeneous power-law distribution through the radial coordinate.It is assumed that the core is subjected to a magnetic field whereas the core is covered by two insulated composite layers.To determine the exact solution,first characteristic equations are derived for different material types in a polar coordinate system,namely,magneto-elastic,elastic,and electro-elastic for the FG,orthotropic,and piezoelectric materials,respectively.The displacement-based method is used instead of the stress-based method to derive a set of closed-form real-valued solutions for both real and complex roots.Based on the elasticity theory,exact solutions for the governing equations are determined layer-by-layer that are considerably more accurate than typical simplified theories.The accuracy of the presented method is compared and validated with the available literature and the finite element simulation.The effects of geometrical and material parameters such as FG index,angular span along with external conditions such as magnetic field,mechanical pressure,and electrical difference are investigated in detail through numerical examples.
基金the financial support provided by the US Army Research Office under grant number W911NF-18-1-0023.
文摘Density-graded cellular materials have tremendous potential in structural applications where impact resistance is required.Cellular materials subjected to high impact loading result in a compaction type deformation,usually modeled using continuum-based shock theory.The resulting governing differential equation of the shock model is nonlinear,and the density gradient further complicates the problem.Earlier studies have employed numerical methods to obtain the solution.In this study,an analytical closed-form solution is proposed to predict the response of density-graded cellular materials subjected to a rigid body impact.Solutions for the velocity of the impinging rigid body mass,energy absorption capacity of the cellular material,and the incident stress are obtained for a single shock propagation.The results obtained are in excellent agreement with the existing numerical solutions found in the literature.The proposed analytical solution can be potentially used for parametric studies and for effectively designing graded structures to mitigate impact.
基金supported by the Major Program of National Nat-ural Science Foundation of China (No. 60710002) Program for Changjiang Scholars and Innovative Research Team in University
文摘A closed-form solution to the linear matrix equation AX-EXF = BY with X and Y unknown and matrix F being in a companion form is proposed, and two equivalent forms of this solution are also presented. The results provide great convenience to the computation and analysis of the solutions to this class of equations, and can perform important functions in many analysis and design problems in descriptor system theory. The results proposed here are parallel to and more general than our early work about the linear matrix equation AX-XF = BY .
基金Project supported by the National Key Basic Research Program of China(Grant No.2012CB026103)the National Natural Science Foundation of China(Grant No.51009136)the Natural Science Foundation of Jiangsu Province,China(Grant No.BK2011212)
文摘Efficient calculation of the electrostatic interactions including repulsive force between charged molecules in a biomolecule system or charged particles in a colloidal system is necessary for the molecular scale or particle scale mechanical analyses of these systems. The electrostatic repulsive force depends on the mid-plane potential between two charged particles. Previous analytical solutions of the mid-plane potential, including those based on simplified assumptions and modern mathematic methods, are reviewed. It is shown that none of these solutions applies to wide ranges of interparticle distance from 0 to 10 and surface potential from 1 to 10. Three previous analytical solutions are chosen to develop a semi-analytical solution which is proven to have more extensive applications. Furthermore, an empirical closed-form expression of mid-plane potential is proposed based on plenty of numerical solutions. This empirical solution has extensive applications, as well as high computational efficiency.
基金supported by the National Natural Science Foundation of China (Grants 11172028, 1372021)Research Fund for the Doctoral Program of Higher Education of China (Grant 20131102110039)the Innovation Foundation of Beihang University for PhD graduates
文摘This article presents closed-form solutions for the frequency analysis of rectangular functionally graded material (FGM) thin plates subjected to initially in-plane loads and with an elastic foundation. Based on classical thin plate theory, the governing differential equations are derived using Hamilton's principle. A neutral surface is used to eliminate stretching-bending coupling in FGM plates on the basis of the assumption of constant Poisson's ratio. The resulting governing equation of FGM thin plates has the same form as homogeneous thin plates. The separation-of-variables method is adopted to obtain solutions for the free vibration problems of rectangular FGM thin plates with separable boundary conditions, including, for example, clamped plates. The obtained normal modes and frequencies are in elegant closed forms, and present formulations and solutions are validated by comparing present results with those in the literature and finite element method results obtained by the authors. A parameter study reveals the effects of the power law index n and aspect ratio a/b on frequencies.
文摘Based on the integral equation formulations and the moment method, a novel closed form solution for analyzing the mutual coupling effect between the cylindrical comformal rectangular microstrip patch antennas is presented. By using this algorithm, the elements of the impedance matrix and exciting vector are cast into closed forms, thus the computational efficiency is improved dramatically. Numerical results are presented to verify the validity and reliability of the algorithm.
基金National Natural Science Foundation of China:[Grant Number 52077217].
文摘Dynamic programming(DP)is frequently used to obtain the optimal solution to the hybrid electric vehicle(HEV)energy management.The trade-off between the accuracy and the computational effort is the biggest problem for the DP method.The closed-form solution to the DP is proposed to solve this problem.Firstly,the affine linear model of the engine fuel rate is obtained based on engine test data.The piecewise linear approximation of the motor power demand is obtained considering the different energy flows in the charging and discharging stages of the battery.Then,the second-order Taylor expansion for the cost matrix at each time and state grid point is introduced to get the closed-form solution of the optimal torque split.The results show that this method can greatly reduce the computing burden by 93%while ensuring near-optimal fuel economy compared with the conventional DP method.
基金Supported by Science and Technology Department of Sichuan Province,No.2020YFS0376National Natural Science Foundation of China,No.81900599Science and Technology Program of Hospital of TCM,Southwest Medical University,No.2022-CXTD-01.
文摘BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.
基金Supported by the National Natural Science Foundation of China(11671403,11671236,12101192)Henan Provincial General Natural Science Foundation Project(232300420113)。
文摘In this paper,we mainly focus on a type of nonlinear Choquard equations with nonconstant potential.Under appropriate hypotheses on potential function and nonlinear terms,we prove that the above Choquard equation with prescribed 2-norm has some normalized solutions by introducing variational methods.
文摘In previous papers, we proposed the important Ztransformations and obtained general solutions to a large number of linear and quasi-linear partial differential equations for the first time. In this paper, we will use the Z1transformation to get the general solutions of some nonlinear partial differential equations for the first time, and use the general solutions to obtain the exact solutions of some typical definite solution problems.
文摘In this paper, we get the N-fold Darboux transformation with multi-parameters for the coupled mKdV equations with the help of a guage transformation of the spectral problem. As an application, some new multi-soliton solutions and complexiton solutions are obtained from choosing the appropriate seed solution. All obtained solutions and N-fold Darboux transformations are expressed using the Vandermonde-like determinants.
文摘This work focuses on a Keller-Segel chemotaxis model, with an emphasis on its conservation laws. Through a new approach combined with the multiplier method, called the mixed method, we obtain conservation vectors that are related and unrelated to symmetric information. In addition, some exact solutions with particular forms are obtained according to the method of conservation laws. These particular solutions are different from the group-invariant solutions.
基金Supported by the National Natural Science Foundation of China(12171247)。
文摘In this short paper, we first establish the existence of periodic solutions to parabolic equation in the whole space by using the probability method. Then, the periodicity of some function of stochastic process is also studied.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 12101572 and 12371256)2024 Shanxi Province Graduate Innovation Project (Grant No. 2024KY615)the Fundamental Research Program of Shanxi Province of China (Grant No. 202403021211002)。
文摘The N-periodic wave solvability problem for the N=1 supersymmetric Sawada–Kotera–Ramani equation is considered by combining the Hirota's bilinear method and the super Riemann theta function. The constraint equations and unknown parameters are redefined, and the numerical calculation process of the N-periodic wave solutions is derived. It has been verified that under certain conditions, the asymptotic relations between N-periodic wave solutions and N-soliton solutions can be established. Some numerical solutions of three-periodic wave are presented. Under the influence of the Grassmann variable, the three-periodic wave solutions will generate an influence band in the middle region, and the amplitude becomes bigger as the distance from the influence band increases.
文摘Colorectal cancer(CRC)is a prevalent malignancy worldwide,posing a significant public health concern.Mounting evidence has confirmed that timely early screening facilitates the detection of incipient CRC,thereby enhancing patient prognosis.Obviously,non-participation of asymptomatic individuals in screening programs hampers early diagnosis and may adversely affect long-term outcomes for CRC patients.In this letter,we provide a comprehensive overview of the current status of early screening practices,while also thoroughly examine the dilemmas and potential solutions associated with early screening for CRC.In response to these issues,we proffer a set of recommendations directed at governmental authorities and the general public,which focus on augmenting financial investment,establishing standardized screening protocols,advancing technological capabilities,and bolstering public awareness campaigns.The importance of collaborative efforts from various stakeholders cannot be overstated in the quest to enhance early detection rates and alleviate the societal burden of CRC.
