The 2022 Honghe M_(S)5.0 seismic event is intriguing due to its occurrence in the south of the Red River Fault,an area historically lacking seismic activities greater than M_(S)5.0.To elucidate the seismogenic mechani...The 2022 Honghe M_(S)5.0 seismic event is intriguing due to its occurrence in the south of the Red River Fault,an area historically lacking seismic activities greater than M_(S)5.0.To elucidate the seismogenic mechanism and scrutinize stress-triggered interactions,we calculated co-seismic and post-seismic Coulomb stress alterations induced by nine historical seismic events(M≥6.0).The analysis reveals that these substantial seismic events provoked co-seismic stress augmentations of 1.409 bar and postseismic stress increments of 0.159 bar.Noteworthy seismic events,such as the 1833 Songming,1877Shiping,1913 Eshan,and 1970 Tonghai earthquakes,catalyzed the occurrence of the Honghe earthquake.Areas of heightened future seismic risk include the southern region of the Red River Fault and the eastern segments of the Shiping-Jianshui and Qujiang faults.Additionally,we assessed the correlation between the spatial distribution of aftershocks and the Coulomb stress shift triggered by the mainshock,taking into account the influence of calculation parameter settings.展开更多
Small-molecule organic solar cells(SMOSCs)have attracted considerable attention owing to the merits of small molecules,such as easy purification,well-defined chemical structure.To achieve high-performance SMOSCs,the r...Small-molecule organic solar cells(SMOSCs)have attracted considerable attention owing to the merits of small molecules,such as easy purification,well-defined chemical structure.To achieve high-performance SMOSCs,the rational design of well-matched donor and acceptor materials is extremely essential.In this work,two new small molecular donor materials with subtle change in the conjugated side thiophene rings are synthesized.The subtle change significantly affects the photovoltaic performance of molecular donors.Compared with chlorinated molecule MDJ-Cl,the non-chlorinated analogue MDJ exhibits decreased miscibility with the non-fullerene acceptor Y6,can more efficiently quench the excitons of Y6.As a result,a improved PCE of 11.16% is obtained for MDJ:Y6 based SMOSCs.The results highlight the importance of fine-tuning the molecular structure to achieve high-performance SMOSCs.展开更多
Liver failure is characterized by the rapid deterioration of liver function,often accompanied by ascites,coagulation dysfunction,hepatic encephalopathy,and other critical complications.Owing to the complex multifacete...Liver failure is characterized by the rapid deterioration of liver function,often accompanied by ascites,coagulation dysfunction,hepatic encephalopathy,and other critical complications.Owing to the complex multifaceted pathogenesis and consequential clinical manifestations of the disease,liver failure displays poor prognosis and warrants comprehensive clinical treatment and management.Liver transplantation remains the only well-established treatment for liver failure.However,several factors including transplantation cost and low organ donation rates limit the rate of liver transplantation.The development of a suitable therapy for liver failure is a significant challenge and remains a cause of concern for the medical world.Granulocyte colony-stimulating factor(G-CSF),a member of the cytokine family of hematopoietic growth factors,is involved in the migration of hematopoietic stem cells into the damaged liver,and effectuates their dedifferentiation into hepatocytes.Liver regeneration involves a complex crosstalk of multiple cell types,including hepatocytes,endothelial cells,and inflammatory cells.Neutrophils and monocytes/macrophages that present different types of innate immune cells were found to play a crucial role in the progression of inflammation and restoration of the liver tissue.G-CSF,known as the most common used cytokine,may also affect these immune cells by combining G-CSF receptors on their surface.The immunomodulatory activity of G-CSF should be studied and described in order to ascertain its therapeutic effect on liver failure.展开更多
Synthetic control of metal oxide nanocrystals with precise size and morphology is of great importance for promising optoelectronic applications due to their unique size-and shape-dependent optical/optoelectronic prope...Synthetic control of metal oxide nanocrystals with precise size and morphology is of great importance for promising optoelectronic applications due to their unique size-and shape-dependent optical/optoelectronic properties.Nevertheless,the understanding of the mechanism for size and morphology control of metal oxide nanocrystals are less studied.Here,we demonstrate that acetic acid,the byproduct of the initial chemical reaction of precursors,plays a dominant role in determining the morphology of indium oxide(In_(2)O_(3))nanocrystals by influencing the nucleation of the nanocrystals formation.Sufficient acetic acid would induce anisotropic growth,leading to the generation of nanoflowers,while limited existence of acetic acid results in sphere-shaped nanocrystals.Furthermore,the effects of geometries of In_(2)O_(3) nanocrystals on their plasmonic properties are studied.The resulting plasmonic In_(2)O_(3) nanocrystals show size-tunable plasmon resonance peaks in the near-infrared to mid-infrared regime and outstanding air/thermal stability.Our work shall give an in-depth understanding of the mechanism for geometry control of nanocrystals and offer more opportunities in potential optoelectronic and photothermal applications based on plasmonic metal oxide nanocrystals.展开更多
基金funded by the Youth Seismic Regime Tracking Project of CEA(2023010129)。
文摘The 2022 Honghe M_(S)5.0 seismic event is intriguing due to its occurrence in the south of the Red River Fault,an area historically lacking seismic activities greater than M_(S)5.0.To elucidate the seismogenic mechanism and scrutinize stress-triggered interactions,we calculated co-seismic and post-seismic Coulomb stress alterations induced by nine historical seismic events(M≥6.0).The analysis reveals that these substantial seismic events provoked co-seismic stress augmentations of 1.409 bar and postseismic stress increments of 0.159 bar.Noteworthy seismic events,such as the 1833 Songming,1877Shiping,1913 Eshan,and 1970 Tonghai earthquakes,catalyzed the occurrence of the Honghe earthquake.Areas of heightened future seismic risk include the southern region of the Red River Fault and the eastern segments of the Shiping-Jianshui and Qujiang faults.Additionally,we assessed the correlation between the spatial distribution of aftershocks and the Coulomb stress shift triggered by the mainshock,taking into account the influence of calculation parameter settings.
基金supported by the National Natural Science Foundation of China(NSFC,Nos.51973169,51703172)the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2020WNLOKF015)the Science Foundation of Wuhan Institute of Technology(No.K202025).
文摘Small-molecule organic solar cells(SMOSCs)have attracted considerable attention owing to the merits of small molecules,such as easy purification,well-defined chemical structure.To achieve high-performance SMOSCs,the rational design of well-matched donor and acceptor materials is extremely essential.In this work,two new small molecular donor materials with subtle change in the conjugated side thiophene rings are synthesized.The subtle change significantly affects the photovoltaic performance of molecular donors.Compared with chlorinated molecule MDJ-Cl,the non-chlorinated analogue MDJ exhibits decreased miscibility with the non-fullerene acceptor Y6,can more efficiently quench the excitons of Y6.As a result,a improved PCE of 11.16% is obtained for MDJ:Y6 based SMOSCs.The results highlight the importance of fine-tuning the molecular structure to achieve high-performance SMOSCs.
基金This work was supported by a grant from the Capital’s Funds for Health Improvement and Research,China(No.2020-1-5031).
文摘Liver failure is characterized by the rapid deterioration of liver function,often accompanied by ascites,coagulation dysfunction,hepatic encephalopathy,and other critical complications.Owing to the complex multifaceted pathogenesis and consequential clinical manifestations of the disease,liver failure displays poor prognosis and warrants comprehensive clinical treatment and management.Liver transplantation remains the only well-established treatment for liver failure.However,several factors including transplantation cost and low organ donation rates limit the rate of liver transplantation.The development of a suitable therapy for liver failure is a significant challenge and remains a cause of concern for the medical world.Granulocyte colony-stimulating factor(G-CSF),a member of the cytokine family of hematopoietic growth factors,is involved in the migration of hematopoietic stem cells into the damaged liver,and effectuates their dedifferentiation into hepatocytes.Liver regeneration involves a complex crosstalk of multiple cell types,including hepatocytes,endothelial cells,and inflammatory cells.Neutrophils and monocytes/macrophages that present different types of innate immune cells were found to play a crucial role in the progression of inflammation and restoration of the liver tissue.G-CSF,known as the most common used cytokine,may also affect these immune cells by combining G-CSF receptors on their surface.The immunomodulatory activity of G-CSF should be studied and described in order to ascertain its therapeutic effect on liver failure.
基金financially supported by the National Natural Science Foundation of China (22005267 and 22105011)the Basic Public Research Program of Zhejiang Province (LGF22B010004 and LY23B010001)+3 种基金the National Key Technologies R&D Program of China (2022YFA1207000)the Research Funds of Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences (A05006C019001 and 2024HIAS-Y008)Hangzhou Science and Technology Bureau of Zhejiang Province (TD2020002)Department of Science and Technology of Zhejiang Province (2024C01192)。
文摘Synthetic control of metal oxide nanocrystals with precise size and morphology is of great importance for promising optoelectronic applications due to their unique size-and shape-dependent optical/optoelectronic properties.Nevertheless,the understanding of the mechanism for size and morphology control of metal oxide nanocrystals are less studied.Here,we demonstrate that acetic acid,the byproduct of the initial chemical reaction of precursors,plays a dominant role in determining the morphology of indium oxide(In_(2)O_(3))nanocrystals by influencing the nucleation of the nanocrystals formation.Sufficient acetic acid would induce anisotropic growth,leading to the generation of nanoflowers,while limited existence of acetic acid results in sphere-shaped nanocrystals.Furthermore,the effects of geometries of In_(2)O_(3) nanocrystals on their plasmonic properties are studied.The resulting plasmonic In_(2)O_(3) nanocrystals show size-tunable plasmon resonance peaks in the near-infrared to mid-infrared regime and outstanding air/thermal stability.Our work shall give an in-depth understanding of the mechanism for geometry control of nanocrystals and offer more opportunities in potential optoelectronic and photothermal applications based on plasmonic metal oxide nanocrystals.
