Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable development.Hydroelectricity generation from ubiquitous and spontaneous phase transitions between liquid and gas...Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable development.Hydroelectricity generation from ubiquitous and spontaneous phase transitions between liquid and gaseous water has been considered a promising strategy for mitigating the energy crisis.Fibrous materials with unique flexibility,processability,multifunctionality,and practicability have been widely applied for fibrous materials-based hydroelectricity generation(FHG).In this review,the power generation mechanisms,design principles,and electricity enhancement factors of FHG are first introduced.Then,the fabrication strategies and characteristics of varied constructions including 1D fiber,1D yarn,2D fabric,2D membrane,3D fibrous framework,and 3D fibrous gel are demonstrated.Afterward,the advanced functions of FHG during water harvesting,proton dissociation,ion separation,and charge accumulation processes are analyzed in detail.Moreover,the potential applications including power supply,energy storage,electrical sensor,and information expression are also discussed.Finally,some existing challenges are considered and prospects for future development are sincerely proposed.展开更多
Benefiting from the development of Federated Learning(FL)and distributed communication systems,large-scale intelligent applications become possible.Distributed devices not only provide adequate training data,but also ...Benefiting from the development of Federated Learning(FL)and distributed communication systems,large-scale intelligent applications become possible.Distributed devices not only provide adequate training data,but also cause privacy leakage and energy consumption.How to optimize the energy consumption in distributed communication systems,while ensuring the privacy of users and model accuracy,has become an urgent challenge.In this paper,we define the FL as a 3-layer architecture including users,agents and server.In order to find a balance among model training accuracy,privacy-preserving effect,and energy consumption,we design the training process of FL as game models.We use an extensive game tree to analyze the key elements that influence the players’decisions in the single game,and then find the incentive mechanism that meet the social norms through the repeated game.The experimental results show that the Nash equilibrium we obtained satisfies the laws of reality,and the proposed incentive mechanism can also promote users to submit high-quality data in FL.Following the multiple rounds of play,the incentive mechanism can help all players find the optimal strategies for energy,privacy,and accuracy of FL in distributed communication systems.展开更多
The degradation of micropollutants in water via ultraviolet(UV)-based advanced oxidation processes(AOPs)is strongly dependent on the water matrix.Various reactive radicals(RRs)formed in UV-AOPs have different reaction...The degradation of micropollutants in water via ultraviolet(UV)-based advanced oxidation processes(AOPs)is strongly dependent on the water matrix.Various reactive radicals(RRs)formed in UV-AOPs have different reaction selectivities toward water matrices and degradation efficiencies for target micropollutants.Hence,process selection and optimization are crucial.This study developed a facilitated prediction method for the photon fluence-based rate constant for micropollutant degradation(K′_(p,MP))in various UV-AOPs by combining model simulation with portable measurement.Portable methods for measuring the scavenging capacities of the principal RRs(RRSCs)involved in UV-AOPs(i.e.,HO^(·),SO_(4)^(·-),and Cl^(·))using a mini-fluidic photoreaction system were proposed.The simulation models consisted of photochemical,quantitative structure–activity relationship,and radical concentration steady-state approximation models.The RRSCs were determined in eight test waters,and a higher RRSC was found to be associated with a more complex water matrix.Then,by taking sulfamethazine,caffeine,and carbamazepine as model micropollutants,the k′_(p,MP) values in various UV-AOPs were predicted and further verified experimentally.A lower k′_(p,MP) was found to be associated with a higher RRSC for a stronger RR competition;for example,k′_(p,MP) values of 130.9 and 332.5 m^(2) einstein^(–1),respectively,were obtained for carbamazepine degradation by UV/H_(2)O_(2) in the raw water(RRSC=9.47×10^(4) s^(-1))and sand-filtered effluent(RRSC=2.87×10^(4) s^(-1))of a drinking water treatment plant.The developed method facilitates process selection and optimization for UV-AOPs,which is essential for increasing the efficiency and cost-effectiveness of water treatment.展开更多
In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses...In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses and strong disturbances and construction conditions such as the application of high prestress.It is essential to study the support components performance under dynamic-static coupling conditions.Based on this,a multi-functional anchorage support dynamic-static coupling performance test system(MAC system)is developed,which can achieve 7 types of testing functions,including single component performance,anchored net performance,anchored rock performance and so on.The bolt and cable mechanical tests are conducted by MAC system under different prestress levels.The results showed that compared to the non-prestress condition,the impact resistance performance of prestressed bolts(cables)is significantly reduced.In the prestress range of 50–160 k N,the maximum reduction rate of impact energy resisted by different types of bolts is 53.9%–61.5%compared to non-prestress condition.In the prestress range of 150–300 k N,the impact energy resisted by high-strength cable is reduced by76.8%–84.6%compared to non-prestress condition.The MAC system achieves dynamic-static coupling performance test,which provide an effective means for the design of anchorage support system.展开更多
We systematically study the electronic structure of a kagome superconductor CsV_(3)Sb_(5)at different temperatures coveringboth its charge density wave state and normal state with angle-resolved photoemission spectros...We systematically study the electronic structure of a kagome superconductor CsV_(3)Sb_(5)at different temperatures coveringboth its charge density wave state and normal state with angle-resolved photoemission spectroscopy.We observe thatthe V-shaped band aroundГshows three different behaviors,referred to as a/a',βandγ,mainly at different temperatures.Detailed investigations confirm that these bands are all from the same bulk Sb-p_(z)origin,but they are quite sensitiveto the sample surface conditions mainly modulated by temperature.Thus,the intriguing temperature dependent electronicbehavior of the band nearГis affected by the sample surface condition,rather than intrinsic electronic behavior originatingfrom the phase transition.Our result systematically reveals the confusing electronic structure behavior of the energy bandsaroundГ,facilitating further exploration of the novel properties in this material.展开更多
Synchrotron radiation has transformed the role of xrays as a mainstream tool for probing the atomic and electronic structure of materials.Synchrotron-based xray sciences have been widely used to study the microscopic ...Synchrotron radiation has transformed the role of xrays as a mainstream tool for probing the atomic and electronic structure of materials.Synchrotron-based xray sciences have been widely used to study the microscopic structure,electronic states,chemical composition.展开更多
AIM: To give the evidence for rationalizing surgical therapy for early gastric cancer with different lymph node status. METHODS: A series of 322 early gastric cancer patients who underwent gastrectomy with more than 1...AIM: To give the evidence for rationalizing surgical therapy for early gastric cancer with different lymph node status. METHODS: A series of 322 early gastric cancer patients who underwent gastrectomy with more than 15 lymph nodes retrieved were reviewed in this study. The rate of lymph node metastasis was calculated. Univariate and multivariate analyses were performed to evaluate the independent factors for predicting lymph node metastasis. RESULTS: No metastasis was detected in No.5, 6 lymph nodes (LN) during proximal gastric cancer total gastrectomy, and in No.10, 11p, 11d during for combined resection of spleen and splenic artery and in No.15 LN during combined resection of transverse colon mesentery. No.11p, 12a, 14v LN were proved negative for metastasis. The global metastastic rate was 14.6% for LN, 5.9% for mucosa, and 22.4% for submucosa carcinoma, respectively. The metastasis in group Ⅱ?was almost limited in No.7, 8a LN. Multivariate analysis identified that the depth of invasion, histological type and lymphatic invasion were independent risk factors for LN metastasis. No metastasis from distal cancer (≤ 1.0 cm in diameter) was detected in group Ⅱ?LN. The metastasis rate increased significantly when the diameter exceeded 3.0 cm. All tumors (≤ 1.0 cm in diameter) with LN metastasis and mucosa invasion showed a depressed macroscopic type, and all protruded carcinomas were > 3.0 cm in diameter. CONCLUSION: Segmental/subtotal gastrectomy plus D1/D1 + No.7 should be performed for carcinoma (≤ 1.0 cm in diameter, protruded type and mucosa invasion).Subtotal gastrectomy plus D2 or D1 + No.7, 8a, 9 is the most rational operation, whereas No.11p, 12a, 14v lymphadenectomy should not be recommended routinely for poorly differentiated and depressed type of submucosa carcinoma (> 3.0 cm in diameter). Total gastrectomy should not be performed in proximal, so does combined resection or D2+/D3 lymphadenectomy.展开更多
Objective： To validate the necessity of increasing the examined lymph node （ELN） count for enhancing the accuracy of prognostic evaluation of gastric cancer （GC） patients after curative gastrectomy in multiple me...Objective： To validate the necessity of increasing the examined lymph node （ELN） count for enhancing the accuracy of prognostic evaluation of gastric cancer （GC） patients after curative gastrectomy in multiple medical centers of China.Methods： The clinicopathological data of 7,620 patients who underwent the curative resection for GC between 2001 and 2011 were included to demonstrate whether the ELN count is indispensable for enhancing the accuracy of prognostic evaluation of GC patients after surgery. After a meticulous stratification by using the cut-point survival analysis, all included 7,620 patients were allocated into three groups as： less than 16 （〈16）, between 16 and 30 （16-30）, and more than 30 （〉30） ELNs. Survival differences among various subgroups of GC patients were analyzed to assess the impact of the ELN count on the stage migration in accordance with the overall survival （OS） of GC patients.Results： Survival analyses revealed that the ELN count was positively correlated with the OS （P：0.001） and was an independent prognostic predictor （P〈0.01） of 7,620 GC patients. Stratum analysis showed that the accuracy of prognostic evaluation could be enhanced when the ELN count was no less than 16 （≥16） for node-negative patients and 〉30 for node-positive patients. Stage migrations were mainly detected in the various subgroups of patients with specific pN stages as follows： pN0 with 16-30 ELNs （pN016-30） and pN0 with 〉30 ELNs （pN0〉30）, pN0 with 〈16 ELNs （pN0〈16） and pNl〉30, pNl〈l6 and pN216_30, pNl：6_30 and pN2〉30, pN3a〈l6 and pN3b16-30, and pN3a〈16 and pN3 b〉30. These findings indicate that increasing the ELN count is a prerequisite to guarantee precisely prognostic evaluation of GC patients.Conclusions： The ELN count should be proposed to be 〉30 for acquiring the accurate prognostic evaluadort for GC patients, especially for node-positive patients.展开更多
AIM:To test the pathogenicity of pseudorabies virus(PRV)variant HN1201 and compare its pathogenicity with a classical PRV Fa strain.METHODS:The pathogenicity of the newly-emerging PRV variant HN1201 was evaluated by d...AIM:To test the pathogenicity of pseudorabies virus(PRV)variant HN1201 and compare its pathogenicity with a classical PRV Fa strain.METHODS:The pathogenicity of the newly-emerging PRV variant HN1201 was evaluated by different inoculating routes,virus loads,and ages of pigs.The classical PRV Fa strain was then used to compare with HN1201 to determine pathogenicity.Clinical symptoms after virus infection were recorded daily and average daily body weight was used to measure the growth performance of pigs.At necropsy,gross pathology and histopathology were used to evaluate the severity of tissue damage caused by virus infection.RESULTS:The results showed that the efficient infection method of RPV HN1201 was via intranasal inoculation at 107 TCID50,and that the virus has high pathogenicity to 35-to 127-d old pigs.Compared with Fa strain,pigs infected with HN1201 showed more severe clinical symptoms and pathological lesions.Immunochemistry results revealed HN1201 had more abundant antigen distribution in extensive organs.CONCLUSION:All of the above results suggest that PRV variant HN1201 was more pathogenic to pigs than the classical Fa strain.展开更多
Additive manufacturing(AM)is an emerging customized three-dimensional(3D)functional product fabrication technology.It provides a higher degree of design freedom,reduces manufacturing steps,cost and production cycles.H...Additive manufacturing(AM)is an emerging customized three-dimensional(3D)functional product fabrication technology.It provides a higher degree of design freedom,reduces manufacturing steps,cost and production cycles.However,existing metallic component 3D printing techniques are mainly for the manufacture of single material components.With the increasing commercial applications of AM technologies,the need for 3D printing of more than one type of dissimilar materials in a single component increases.Therefore,investigations on multi-material AM(MMAM)emerge over the past decade.Lasers are currently widely used for the AM of metallic components where high temperatures are involved.Here we report the progress and trend in laser-based macro-and micro-scale AM of multiple metallic components.The methods covered in this paper include laser powder bed fusion,laser powder directed energy deposition,and laser-induced forward transfer for MMAM applications.The principles and process/material characteristics are described.Potential applications and challenges are discussed.Finally,future research directions and prospects are proposed.展开更多
AIM:To investigate the expression and prognostic role of pyruvate dehydrogenase(PDH) in gastric cancer(GC).METHODS:This study included 265 patients(194 male,71 female,mean age 59 years(range,29-81 years) with GC who u...AIM:To investigate the expression and prognostic role of pyruvate dehydrogenase(PDH) in gastric cancer(GC).METHODS:This study included 265 patients(194 male,71 female,mean age 59 years(range,29-81 years) with GC who underwent curative surgery at the First Affiliated Hospital of China Medical University from January 2006 to May 2007.All patients were followed up for more than 5 years.Patient-derived paraffin embedded GC specimens were collected for tissue microarrays(TMAs).We examined PDH expression by immunohistochemistry in TMAs containing tumor tissue and matched nonneoplastic mucosa.Immunoreactivity was evaluated independently by two researchers.Overall survival(OS) rates were determined using the Kaplan-Meier estimator.Correlations with other clinicopathologic factors were evaluated by two-tailed χ2 tests or a two-tailed t-test.The Cox proportional-hazard model was used in univariate analysis and multivariate analysis to identify factors significantly correlated with prognosis.RESULTS:Immunohistochemistry showed that 35.47% of total cancer tissue specimens had cytoplasmic PDH staining.PDH expression was much higher in normal mucosa specimens(75.09%;P = 0.001).PDH expression was correlated with Lauren grade(70.77% in intestinal type vs 40.0% in diffuse type;P = 0.001),lymph node metastasis(65.43% with no metastasis vs 51.09% with metastasis;P = 0.033),lymphatic invasion(61.62% with no invasion vs 38.81% with invasion;P = 0.002),histologic subtypes(70.77% in intestinal type vs 40.0% in diffuse type;P = 0.001) and tumor-node-metastasis(TNM) stage(39% in poorly differentiated vs 65.91% in well differentiated and 67.11% in moderately differentiated;P = 0.001) in GC.PDH expression in cancer tissue was significantly associated with higher OS(P < 0.001).The multivariate analysis adjusted for age,Lauren classification,TNM stage,lymph node metastasis,histological type,tumor size,depth of invasion and lymphatic invasion showed that the PDH expression in GC was an independent prognostic factor for higher OS(HR = 0.608,95%CI:0.504-0.734,P < 0.001).CONCLUSION:Our study indicated that PDH expression is an independent prognostic factor in GC patients and that positive expression of PDH may be predictive of favorable outcomes.展开更多
Tremendous progress of developing nuclear magnetic resonance(NMR)fluid analyzer has been witnessed in the oil industry for last two decades.This device allows extensive and accurate exploration of fluid properties,suc...Tremendous progress of developing nuclear magnetic resonance(NMR)fluid analyzer has been witnessed in the oil industry for last two decades.This device allows extensive and accurate exploration of fluid properties,such as its hydrogen content,composition,viscosity,hydrogen index(HI),mud filtrate invasion,gas to oil ratio,average velocity,velocity distribution etc.,in the situations of in situ downhole or surface Petro-pipelines.In this review article,we focus on the design principle,manufacturing,implementation,methodology and applications of NMR fluid analyzer to oil and gas industry.A detailed description of the state-of-art NMR fluid analyzers was firstly given to exhibit their respective characteristics.With these experiences on hand,we introduced a series of NMR fluid analyzers designed by us at China University of Petroleum-Beijing with continuous optimizations,in terms of magnet construction,antenna layout,circuit design and operating surroundings.These systems discussed in this article have been demonstrated to achieve multiple NMR parameter acquisition when the fluid is in stationary or flowing state.In the end,a prototype was fabricated and validated considering a vast of engineering influences,such as variable temperatures in a large range,high pressure,limited volume,detection efficiency,etc.A particular emphasis of this paper is to expedite the measurement efficiency of the NMR fluid analyzer to reduce the operation costs.This dilemma can be Figured out by upgrading both pulse sequence and observational mode.For different fluid states,two rapid pulse sequences were proposed to sufficiently obtain the multi-dimensional NMR correlation map.Meanwhile,two observational modes were developed to take full advantage of the polarization time,during which the individual antenna was systematically switched.Another domain of interest in this review concerns the applications of this new tool.For stationary fluids case,accurate identification of fluid properties is of great value for scheme building in oil and gas exploration process.Particularly,it can acquire the fluid content by different NMR responses of different components.In addition,with Bloembergen theory and Stokes-Einstein equation,not only molecular dynamics and composition,but also oil viscosity can be readily evaluated.Moreover,HI information of crude oils will be speculated through partial least square regression.As for flowing fluids case,velocity is a significant parameter to understand the in situ fluid exploitation and therefore evaluate the productivity of certain oil wells or pipelines.Regarding to the unique magnet and antenna designs in our NMR fluid analyzer;this review adopts two distinct methods to obtain flow velocity at a wide rating scale.The first one is a time-of-flight method adaptive in a homogeneous magnetic field,which is suitable in the case of fluid at high flow velocity.The other one relies on the adjacent echo phase difference at a magnetic field with constant gradient,which is preferred for relatively low flow velocity.In the near future,this tool will be tested underground to offer individual fluid velocities by combining both the stationary and flowing analysis methods.展开更多
To cope with the arbitrariness of the network delays,a novel method,referred to as the composite particle filter approach based on variational Bayesian(VB-CPF),is proposed herein to estimate the clock skew and clock o...To cope with the arbitrariness of the network delays,a novel method,referred to as the composite particle filter approach based on variational Bayesian(VB-CPF),is proposed herein to estimate the clock skew and clock offset in wireless sensor networks.VB-CPF is an improvement of the Gaussian mixture kalman particle filter(GMKPF)algorithm.In GMKPF,Expectation-Maximization(EM)algorithm needs to determine the number of mixture components in advance,and it is easy to generate overfitting and underfitting.Variational Bayesian EM(VB-EM)algorithm is introduced in this paper to determine the number of mixture components adaptively according to the observations.Moreover,to solve the problem of data packet loss caused by unreliable links,we propose a robust time synchronization(RTS)method in this paper.RTS establishes an autoregressive model for clock skew,and calculates the clock parameters based on the established autoregressive model in case of packet loss.The final simulation results illustrate that VB-CPF yields much more accurate results relative to GMKPF when the network delays are modeled in terms of an asymmetric Gaussian distribution.Moreover,RTS shows good robustness to the continuous and random dropout of time messages.展开更多
Background:Currently,there is no formal consensus regarding a standard classification for gastric cancer(GC)patients with<16 retrieved lymph nodes(rLNs).Here,this study aimed to validate a practical lymph node(LN)s...Background:Currently,there is no formal consensus regarding a standard classification for gastric cancer(GC)patients with<16 retrieved lymph nodes(rLNs).Here,this study aimed to validate a practical lymph node(LN)staging strategy to homogenize the nodal classification of GC cohorts comprising of both<16(Limited set)and≥16(Adequate set)rLNs.Methods:All patients in this study underwent R0 gastrectomy.The overall survival(OS)difference between the Limited and Adequate set from a large Chinese multicenter dataset was analyzed.Using the 8th American Joint Committee on Cancer(AJCC)pathological nodal classification(pN)for GC as base,a modified nodal classification(N’)resembling similar analogy as the 8th AJCC pN classification was developed.The performance of the proposed and 8th AJCC GC subgroups was compared and validated using the Surveillance,Epidemiology,and End Results(SEER)dataset comprising of 10,208 multi-ethnic GC cases.Results:Significant difference in OS between the Limited and Adequate set(corresponding N0–N3a)using the 8th AJCC system was observed but the OS of N0_(limited)vs.N1_(adequate),N1_(limited)vs.N2_(adequate),N2_(limited)vs.N3_(aadequate),and N3_(alimited)vs.N3_(badequate)subgroups was almost similar in the Chinese dataset.Therefore,we formulated an N’classification whereby only the nodal subgroups of the Limited set,except for pT1N0M0 cases as they underwent less extensive surgeries(D1 or D1+gastrectomy),were re-classified to one higher nodal subgroup,while those of the Adequate set remained unchanged(N’0=N0_(adequate)+pT1N0M0_(limited),N’1=N1_(adequate)+N0_(limited)(excluding pT1N0M0_(limited)),N’2=N2_(adequate)+N1_(limited),N’3a=N3_(aadequate)+N2_(limited),and N’3b=N3_(badequate)+N3_(alimited)).This N’classification demonstrated less heterogeneity in OS between the Limited and Adequate subgroups.Further analyses demonstrated superior statistical performance of the pTN’M system over the 8th AJCC edition and was successfully validated using the SEER dataset.Conclusion:The proposed nodal staging strategy was successfully validated in large multi-ethnic GC datasets and represents a practical approach for homogenizing the classification of GC cohorts comprising of patients with<16 and≥16 rLNs.展开更多
For enhancing the control effectiveness,we firstly design a fuzzy logic based sliding mode controller(FSMC)for nonlinear crane systems.On basis of overhead crane dynamic characteristic,the sliding mode function with r...For enhancing the control effectiveness,we firstly design a fuzzy logic based sliding mode controller(FSMC)for nonlinear crane systems.On basis of overhead crane dynamic characteristic,the sliding mode function with regard to trolley position and payload angle.Additionally,in order to eliminate the chattering problem of sliding mode control,the fuzzy logic theory is adopted to soften the control performance.Moreover,aiming at the FSMC parameter setting problem,a DE algorithm based optimization scheme is proposed for enhancing the control performance.Finally,by implementing the computer simulation,the DE based FSMC can effectively tackle the overhead crane sway problem and avoid unexpected accident greatly.展开更多
Kinds of complex-structure wells can effectively improve production,which are widely used.However,in the process of drilling and completion,complex-structure wells with long drilling cycle and large exposed area of re...Kinds of complex-structure wells can effectively improve production,which are widely used.However,in the process of drilling and completion,complex-structure wells with long drilling cycle and large exposed area of reservoir can lead to the fact that reservoir near wellbore is more vulnerable to the working fluid invasion,resulting in more serious formation damage.In order to quantitatively describe the reservoir formation damage in the construction of complex-structure well,taking the inclined well section as the research object,the coordinate transformation method and conformal transformation method are given according to the flow characteristics of reservoir near wellbore in anisotropic reservoir.Then the local skin factor in orthogonal plane of wellbore is deduced.Considering the un-even distribution of local skin factor along the wellbore,the oscillation decreasing model and empirical equation model of damage zone radius distribution along the wellbore direction are established and then the total skin factor model of the whole well is superimposed to realize the reservoir damage evaluation of complex-structure wells.Combining the skin factor model with the production model,the production of complex-structure wells can be predicted more accurately.The two field application cases show that the accuracy of the model can be more than 90%,which can also fully reflect the invasion characteristics of drilling and completion fluid in any well section of complex-structure wells in anisotropic reservoir,so as to further provide guidance for the scientific establish-ment of reservoir production system.展开更多
基金funding support from the National Key Research and Development Program of China(No.2022YFB3805800)the National Natural Science Foundation of China(52173059)+1 种基金The Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions(21KJA540002)Jiangsu Funding Program for Excellent Postdoctoral Talent(2022ZB555).
文摘Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable development.Hydroelectricity generation from ubiquitous and spontaneous phase transitions between liquid and gaseous water has been considered a promising strategy for mitigating the energy crisis.Fibrous materials with unique flexibility,processability,multifunctionality,and practicability have been widely applied for fibrous materials-based hydroelectricity generation(FHG).In this review,the power generation mechanisms,design principles,and electricity enhancement factors of FHG are first introduced.Then,the fabrication strategies and characteristics of varied constructions including 1D fiber,1D yarn,2D fabric,2D membrane,3D fibrous framework,and 3D fibrous gel are demonstrated.Afterward,the advanced functions of FHG during water harvesting,proton dissociation,ion separation,and charge accumulation processes are analyzed in detail.Moreover,the potential applications including power supply,energy storage,electrical sensor,and information expression are also discussed.Finally,some existing challenges are considered and prospects for future development are sincerely proposed.
基金sponsored by the National Key R&D Program of China(No.2018YFB2100400)the National Natural Science Foundation of China(No.62002077,61872100)+4 种基金the Major Research Plan of the National Natural Science Foundation of China(92167203)the Guangdong Basic and Applied Basic Research Foundation(No.2020A1515110385)the China Postdoctoral Science Foundation(No.2022M710860)the Zhejiang Lab(No.2020NF0AB01)Guangzhou Science and Technology Plan Project(202102010440).
文摘Benefiting from the development of Federated Learning(FL)and distributed communication systems,large-scale intelligent applications become possible.Distributed devices not only provide adequate training data,but also cause privacy leakage and energy consumption.How to optimize the energy consumption in distributed communication systems,while ensuring the privacy of users and model accuracy,has become an urgent challenge.In this paper,we define the FL as a 3-layer architecture including users,agents and server.In order to find a balance among model training accuracy,privacy-preserving effect,and energy consumption,we design the training process of FL as game models.We use an extensive game tree to analyze the key elements that influence the players’decisions in the single game,and then find the incentive mechanism that meet the social norms through the repeated game.The experimental results show that the Nash equilibrium we obtained satisfies the laws of reality,and the proposed incentive mechanism can also promote users to submit high-quality data in FL.Following the multiple rounds of play,the incentive mechanism can help all players find the optimal strategies for energy,privacy,and accuracy of FL in distributed communication systems.
基金supported by the National Natural Science Foundation of China(52222002)Bureau of International Cooperation of Chinese Academy of Sciences(032GJHZ2022035MI)State Key Laboratory of Environmental Aquatic Chemistry(23Z01ESPCR).
文摘The degradation of micropollutants in water via ultraviolet(UV)-based advanced oxidation processes(AOPs)is strongly dependent on the water matrix.Various reactive radicals(RRs)formed in UV-AOPs have different reaction selectivities toward water matrices and degradation efficiencies for target micropollutants.Hence,process selection and optimization are crucial.This study developed a facilitated prediction method for the photon fluence-based rate constant for micropollutant degradation(K′_(p,MP))in various UV-AOPs by combining model simulation with portable measurement.Portable methods for measuring the scavenging capacities of the principal RRs(RRSCs)involved in UV-AOPs(i.e.,HO^(·),SO_(4)^(·-),and Cl^(·))using a mini-fluidic photoreaction system were proposed.The simulation models consisted of photochemical,quantitative structure–activity relationship,and radical concentration steady-state approximation models.The RRSCs were determined in eight test waters,and a higher RRSC was found to be associated with a more complex water matrix.Then,by taking sulfamethazine,caffeine,and carbamazepine as model micropollutants,the k′_(p,MP) values in various UV-AOPs were predicted and further verified experimentally.A lower k′_(p,MP) was found to be associated with a higher RRSC for a stronger RR competition;for example,k′_(p,MP) values of 130.9 and 332.5 m^(2) einstein^(–1),respectively,were obtained for carbamazepine degradation by UV/H_(2)O_(2) in the raw water(RRSC=9.47×10^(4) s^(-1))and sand-filtered effluent(RRSC=2.87×10^(4) s^(-1))of a drinking water treatment plant.The developed method facilitates process selection and optimization for UV-AOPs,which is essential for increasing the efficiency and cost-effectiveness of water treatment.
基金supported by the National Natural Science Foundation of China(Nos.51927807,52074164,42277174,42077267 and 42177130)the Natural Science Foundation of Shandong Province,China(No.ZR2020JQ23)China University of Mining and Technology(Beijing)Top Innovative Talent Cultivation Fund for Doctoral Students(No.BBJ2023048)。
文摘In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses and strong disturbances and construction conditions such as the application of high prestress.It is essential to study the support components performance under dynamic-static coupling conditions.Based on this,a multi-functional anchorage support dynamic-static coupling performance test system(MAC system)is developed,which can achieve 7 types of testing functions,including single component performance,anchored net performance,anchored rock performance and so on.The bolt and cable mechanical tests are conducted by MAC system under different prestress levels.The results showed that compared to the non-prestress condition,the impact resistance performance of prestressed bolts(cables)is significantly reduced.In the prestress range of 50–160 k N,the maximum reduction rate of impact energy resisted by different types of bolts is 53.9%–61.5%compared to non-prestress condition.In the prestress range of 150–300 k N,the impact energy resisted by high-strength cable is reduced by76.8%–84.6%compared to non-prestress condition.The MAC system achieves dynamic-static coupling performance test,which provide an effective means for the design of anchorage support system.
基金supported by the National Natural Science Foundation of China(Grant Nos.12174362 and 92065202)the Innovation Program for Quantum Science and Technology(Grant No.2021ZD0302803)the New Cornerstone Science Foundation.Part of this research used Beamline 03U of the Shanghai Synchrotron Radiation Facility,which is supported by ME2 project under contract No.11227902 from the National Natural Science Foundation of China.
文摘We systematically study the electronic structure of a kagome superconductor CsV_(3)Sb_(5)at different temperatures coveringboth its charge density wave state and normal state with angle-resolved photoemission spectroscopy.We observe thatthe V-shaped band aroundГshows three different behaviors,referred to as a/a',βandγ,mainly at different temperatures.Detailed investigations confirm that these bands are all from the same bulk Sb-p_(z)origin,but they are quite sensitiveto the sample surface conditions mainly modulated by temperature.Thus,the intriguing temperature dependent electronicbehavior of the band nearГis affected by the sample surface condition,rather than intrinsic electronic behavior originatingfrom the phase transition.Our result systematically reveals the confusing electronic structure behavior of the energy bandsaroundГ,facilitating further exploration of the novel properties in this material.
文摘Synchrotron radiation has transformed the role of xrays as a mainstream tool for probing the atomic and electronic structure of materials.Synchrotron-based xray sciences have been widely used to study the microscopic structure,electronic states,chemical composition.
基金Supported by the National Natural Science Foundation of China, No. 30370640
文摘AIM: To give the evidence for rationalizing surgical therapy for early gastric cancer with different lymph node status. METHODS: A series of 322 early gastric cancer patients who underwent gastrectomy with more than 15 lymph nodes retrieved were reviewed in this study. The rate of lymph node metastasis was calculated. Univariate and multivariate analyses were performed to evaluate the independent factors for predicting lymph node metastasis. RESULTS: No metastasis was detected in No.5, 6 lymph nodes (LN) during proximal gastric cancer total gastrectomy, and in No.10, 11p, 11d during for combined resection of spleen and splenic artery and in No.15 LN during combined resection of transverse colon mesentery. No.11p, 12a, 14v LN were proved negative for metastasis. The global metastastic rate was 14.6% for LN, 5.9% for mucosa, and 22.4% for submucosa carcinoma, respectively. The metastasis in group Ⅱ?was almost limited in No.7, 8a LN. Multivariate analysis identified that the depth of invasion, histological type and lymphatic invasion were independent risk factors for LN metastasis. No metastasis from distal cancer (≤ 1.0 cm in diameter) was detected in group Ⅱ?LN. The metastasis rate increased significantly when the diameter exceeded 3.0 cm. All tumors (≤ 1.0 cm in diameter) with LN metastasis and mucosa invasion showed a depressed macroscopic type, and all protruded carcinomas were > 3.0 cm in diameter. CONCLUSION: Segmental/subtotal gastrectomy plus D1/D1 + No.7 should be performed for carcinoma (≤ 1.0 cm in diameter, protruded type and mucosa invasion).Subtotal gastrectomy plus D2 or D1 + No.7, 8a, 9 is the most rational operation, whereas No.11p, 12a, 14v lymphadenectomy should not be recommended routinely for poorly differentiated and depressed type of submucosa carcinoma (> 3.0 cm in diameter). Total gastrectomy should not be performed in proximal, so does combined resection or D2+/D3 lymphadenectomy.
基金supported in part by grants from the Programs of National Natural Science Foundation of China(No.81572372,No.81172080,No.81201773,No.81572372)National Key Research and Development Program(MOST-2016YFC1303202)+2 种基金National Precision Medicine Research Program(2017YFC0908300)the Application Foundation and Advanced Technology Program of Tianjin Municipal Science and Technology Commission(15JCYBJC24800)the National Key Clinical Specialist Construction Programs of China(2013-544)
文摘Objective： To validate the necessity of increasing the examined lymph node （ELN） count for enhancing the accuracy of prognostic evaluation of gastric cancer （GC） patients after curative gastrectomy in multiple medical centers of China.Methods： The clinicopathological data of 7,620 patients who underwent the curative resection for GC between 2001 and 2011 were included to demonstrate whether the ELN count is indispensable for enhancing the accuracy of prognostic evaluation of GC patients after surgery. After a meticulous stratification by using the cut-point survival analysis, all included 7,620 patients were allocated into three groups as： less than 16 （〈16）, between 16 and 30 （16-30）, and more than 30 （〉30） ELNs. Survival differences among various subgroups of GC patients were analyzed to assess the impact of the ELN count on the stage migration in accordance with the overall survival （OS） of GC patients.Results： Survival analyses revealed that the ELN count was positively correlated with the OS （P：0.001） and was an independent prognostic predictor （P〈0.01） of 7,620 GC patients. Stratum analysis showed that the accuracy of prognostic evaluation could be enhanced when the ELN count was no less than 16 （≥16） for node-negative patients and 〉30 for node-positive patients. Stage migrations were mainly detected in the various subgroups of patients with specific pN stages as follows： pN0 with 16-30 ELNs （pN016-30） and pN0 with 〉30 ELNs （pN0〉30）, pN0 with 〈16 ELNs （pN0〈16） and pNl〉30, pNl〈l6 and pN216_30, pNl：6_30 and pN2〉30, pN3a〈l6 and pN3b16-30, and pN3a〈16 and pN3 b〉30. These findings indicate that increasing the ELN count is a prerequisite to guarantee precisely prognostic evaluation of GC patients.Conclusions： The ELN count should be proposed to be 〉30 for acquiring the accurate prognostic evaluadort for GC patients, especially for node-positive patients.
基金Supported by Major Science and Technology Program in Henan Province,No.131100110200
文摘AIM:To test the pathogenicity of pseudorabies virus(PRV)variant HN1201 and compare its pathogenicity with a classical PRV Fa strain.METHODS:The pathogenicity of the newly-emerging PRV variant HN1201 was evaluated by different inoculating routes,virus loads,and ages of pigs.The classical PRV Fa strain was then used to compare with HN1201 to determine pathogenicity.Clinical symptoms after virus infection were recorded daily and average daily body weight was used to measure the growth performance of pigs.At necropsy,gross pathology and histopathology were used to evaluate the severity of tissue damage caused by virus infection.RESULTS:The results showed that the efficient infection method of RPV HN1201 was via intranasal inoculation at 107 TCID50,and that the virus has high pathogenicity to 35-to 127-d old pigs.Compared with Fa strain,pigs infected with HN1201 showed more severe clinical symptoms and pathological lesions.Immunochemistry results revealed HN1201 had more abundant antigen distribution in extensive organs.CONCLUSION:All of the above results suggest that PRV variant HN1201 was more pathogenic to pigs than the classical Fa strain.
文摘Additive manufacturing(AM)is an emerging customized three-dimensional(3D)functional product fabrication technology.It provides a higher degree of design freedom,reduces manufacturing steps,cost and production cycles.However,existing metallic component 3D printing techniques are mainly for the manufacture of single material components.With the increasing commercial applications of AM technologies,the need for 3D printing of more than one type of dissimilar materials in a single component increases.Therefore,investigations on multi-material AM(MMAM)emerge over the past decade.Lasers are currently widely used for the AM of metallic components where high temperatures are involved.Here we report the progress and trend in laser-based macro-and micro-scale AM of multiple metallic components.The methods covered in this paper include laser powder bed fusion,laser powder directed energy deposition,and laser-induced forward transfer for MMAM applications.The principles and process/material characteristics are described.Potential applications and challenges are discussed.Finally,future research directions and prospects are proposed.
基金Grants from the research projects in Liaoning Province Science and Technology Department,No.2007225017,No.2009225011-2 and No.2011415052Science and Technology projects in Shenyang City,No.F11-264-1-19
文摘AIM:To investigate the expression and prognostic role of pyruvate dehydrogenase(PDH) in gastric cancer(GC).METHODS:This study included 265 patients(194 male,71 female,mean age 59 years(range,29-81 years) with GC who underwent curative surgery at the First Affiliated Hospital of China Medical University from January 2006 to May 2007.All patients were followed up for more than 5 years.Patient-derived paraffin embedded GC specimens were collected for tissue microarrays(TMAs).We examined PDH expression by immunohistochemistry in TMAs containing tumor tissue and matched nonneoplastic mucosa.Immunoreactivity was evaluated independently by two researchers.Overall survival(OS) rates were determined using the Kaplan-Meier estimator.Correlations with other clinicopathologic factors were evaluated by two-tailed χ2 tests or a two-tailed t-test.The Cox proportional-hazard model was used in univariate analysis and multivariate analysis to identify factors significantly correlated with prognosis.RESULTS:Immunohistochemistry showed that 35.47% of total cancer tissue specimens had cytoplasmic PDH staining.PDH expression was much higher in normal mucosa specimens(75.09%;P = 0.001).PDH expression was correlated with Lauren grade(70.77% in intestinal type vs 40.0% in diffuse type;P = 0.001),lymph node metastasis(65.43% with no metastasis vs 51.09% with metastasis;P = 0.033),lymphatic invasion(61.62% with no invasion vs 38.81% with invasion;P = 0.002),histologic subtypes(70.77% in intestinal type vs 40.0% in diffuse type;P = 0.001) and tumor-node-metastasis(TNM) stage(39% in poorly differentiated vs 65.91% in well differentiated and 67.11% in moderately differentiated;P = 0.001) in GC.PDH expression in cancer tissue was significantly associated with higher OS(P < 0.001).The multivariate analysis adjusted for age,Lauren classification,TNM stage,lymph node metastasis,histological type,tumor size,depth of invasion and lymphatic invasion showed that the PDH expression in GC was an independent prognostic factor for higher OS(HR = 0.608,95%CI:0.504-0.734,P < 0.001).CONCLUSION:Our study indicated that PDH expression is an independent prognostic factor in GC patients and that positive expression of PDH may be predictive of favorable outcomes.
基金supported by National Natural Science Foundation of China(Grant Nos.21427812,41674137,51974337)National Science and Technology Major Project of China(2017ZX05019002-008)+1 种基金National"111 Project"(B13010)"863 Project"(2013AA064605)。
文摘Tremendous progress of developing nuclear magnetic resonance(NMR)fluid analyzer has been witnessed in the oil industry for last two decades.This device allows extensive and accurate exploration of fluid properties,such as its hydrogen content,composition,viscosity,hydrogen index(HI),mud filtrate invasion,gas to oil ratio,average velocity,velocity distribution etc.,in the situations of in situ downhole or surface Petro-pipelines.In this review article,we focus on the design principle,manufacturing,implementation,methodology and applications of NMR fluid analyzer to oil and gas industry.A detailed description of the state-of-art NMR fluid analyzers was firstly given to exhibit their respective characteristics.With these experiences on hand,we introduced a series of NMR fluid analyzers designed by us at China University of Petroleum-Beijing with continuous optimizations,in terms of magnet construction,antenna layout,circuit design and operating surroundings.These systems discussed in this article have been demonstrated to achieve multiple NMR parameter acquisition when the fluid is in stationary or flowing state.In the end,a prototype was fabricated and validated considering a vast of engineering influences,such as variable temperatures in a large range,high pressure,limited volume,detection efficiency,etc.A particular emphasis of this paper is to expedite the measurement efficiency of the NMR fluid analyzer to reduce the operation costs.This dilemma can be Figured out by upgrading both pulse sequence and observational mode.For different fluid states,two rapid pulse sequences were proposed to sufficiently obtain the multi-dimensional NMR correlation map.Meanwhile,two observational modes were developed to take full advantage of the polarization time,during which the individual antenna was systematically switched.Another domain of interest in this review concerns the applications of this new tool.For stationary fluids case,accurate identification of fluid properties is of great value for scheme building in oil and gas exploration process.Particularly,it can acquire the fluid content by different NMR responses of different components.In addition,with Bloembergen theory and Stokes-Einstein equation,not only molecular dynamics and composition,but also oil viscosity can be readily evaluated.Moreover,HI information of crude oils will be speculated through partial least square regression.As for flowing fluids case,velocity is a significant parameter to understand the in situ fluid exploitation and therefore evaluate the productivity of certain oil wells or pipelines.Regarding to the unique magnet and antenna designs in our NMR fluid analyzer;this review adopts two distinct methods to obtain flow velocity at a wide rating scale.The first one is a time-of-flight method adaptive in a homogeneous magnetic field,which is suitable in the case of fluid at high flow velocity.The other one relies on the adjacent echo phase difference at a magnetic field with constant gradient,which is preferred for relatively low flow velocity.In the near future,this tool will be tested underground to offer individual fluid velocities by combining both the stationary and flowing analysis methods.
基金This work was supported by the National Natural Science Foundation of China(No.61672299)the Natural Science Foundation of the Higher Education Institutions of Jiangsu Province of China(No.18KJB520035)+2 种基金the Youth Foundation of Nanjing University of Finance and Economics(No.L-JXL18002)the Youth Foundation of Nanjing University of Posts and Telecommunications(No.NY218142)the Natural Science Foundation of Jiangsu Province(No.BK20160913).
文摘To cope with the arbitrariness of the network delays,a novel method,referred to as the composite particle filter approach based on variational Bayesian(VB-CPF),is proposed herein to estimate the clock skew and clock offset in wireless sensor networks.VB-CPF is an improvement of the Gaussian mixture kalman particle filter(GMKPF)algorithm.In GMKPF,Expectation-Maximization(EM)algorithm needs to determine the number of mixture components in advance,and it is easy to generate overfitting and underfitting.Variational Bayesian EM(VB-EM)algorithm is introduced in this paper to determine the number of mixture components adaptively according to the observations.Moreover,to solve the problem of data packet loss caused by unreliable links,we propose a robust time synchronization(RTS)method in this paper.RTS establishes an autoregressive model for clock skew,and calculates the clock parameters based on the established autoregressive model in case of packet loss.The final simulation results illustrate that VB-CPF yields much more accurate results relative to GMKPF when the network delays are modeled in terms of an asymmetric Gaussian distribution.Moreover,RTS shows good robustness to the continuous and random dropout of time messages.
基金the National Natural Science Foundation of China(81802451)the China Postdoctoral Science Foundation(2017M622879)+1 种基金the Natural Science Foundation of Guangdong Province(2114050002182,2018A030313827 and 2021A1515011327)the Young Teacher Training Program of Sun Yat-sen University(19ykpy172).
文摘Background:Currently,there is no formal consensus regarding a standard classification for gastric cancer(GC)patients with<16 retrieved lymph nodes(rLNs).Here,this study aimed to validate a practical lymph node(LN)staging strategy to homogenize the nodal classification of GC cohorts comprising of both<16(Limited set)and≥16(Adequate set)rLNs.Methods:All patients in this study underwent R0 gastrectomy.The overall survival(OS)difference between the Limited and Adequate set from a large Chinese multicenter dataset was analyzed.Using the 8th American Joint Committee on Cancer(AJCC)pathological nodal classification(pN)for GC as base,a modified nodal classification(N’)resembling similar analogy as the 8th AJCC pN classification was developed.The performance of the proposed and 8th AJCC GC subgroups was compared and validated using the Surveillance,Epidemiology,and End Results(SEER)dataset comprising of 10,208 multi-ethnic GC cases.Results:Significant difference in OS between the Limited and Adequate set(corresponding N0–N3a)using the 8th AJCC system was observed but the OS of N0_(limited)vs.N1_(adequate),N1_(limited)vs.N2_(adequate),N2_(limited)vs.N3_(aadequate),and N3_(alimited)vs.N3_(badequate)subgroups was almost similar in the Chinese dataset.Therefore,we formulated an N’classification whereby only the nodal subgroups of the Limited set,except for pT1N0M0 cases as they underwent less extensive surgeries(D1 or D1+gastrectomy),were re-classified to one higher nodal subgroup,while those of the Adequate set remained unchanged(N’0=N0_(adequate)+pT1N0M0_(limited),N’1=N1_(adequate)+N0_(limited)(excluding pT1N0M0_(limited)),N’2=N2_(adequate)+N1_(limited),N’3a=N3_(aadequate)+N2_(limited),and N’3b=N3_(badequate)+N3_(alimited)).This N’classification demonstrated less heterogeneity in OS between the Limited and Adequate subgroups.Further analyses demonstrated superior statistical performance of the pTN’M system over the 8th AJCC edition and was successfully validated using the SEER dataset.Conclusion:The proposed nodal staging strategy was successfully validated in large multi-ethnic GC datasets and represents a practical approach for homogenizing the classification of GC cohorts comprising of patients with<16 and≥16 rLNs.
基金This work is supported by the Natural Science Foundation of Jiangsu Province(No.BK20160913)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(No.18KJB520035)+4 种基金the High Level Teacher Research Foundation of Nanjing University of Posts and Telecommunications(No.NY2016021)the Incubation Foundation of Nanjing University of Posts and Telecommunications(No.NY217055)Postdoctoral Foundation of Jiangsu Province(No.1701016A)Natural Science Foundation of China(No.61602259,No.61373135 and No.61672299)National Engineering Laboratory for Logistics Information Technology,YuanTong Express Co.LTD.
文摘For enhancing the control effectiveness,we firstly design a fuzzy logic based sliding mode controller(FSMC)for nonlinear crane systems.On basis of overhead crane dynamic characteristic,the sliding mode function with regard to trolley position and payload angle.Additionally,in order to eliminate the chattering problem of sliding mode control,the fuzzy logic theory is adopted to soften the control performance.Moreover,aiming at the FSMC parameter setting problem,a DE algorithm based optimization scheme is proposed for enhancing the control performance.Finally,by implementing the computer simulation,the DE based FSMC can effectively tackle the overhead crane sway problem and avoid unexpected accident greatly.
基金supported by National Natural Science Foundation of China(Grant No.52004297 and Grant No.51991361)China Postdoctoral Science Foundation(Grant No.BX20200384)。
文摘Kinds of complex-structure wells can effectively improve production,which are widely used.However,in the process of drilling and completion,complex-structure wells with long drilling cycle and large exposed area of reservoir can lead to the fact that reservoir near wellbore is more vulnerable to the working fluid invasion,resulting in more serious formation damage.In order to quantitatively describe the reservoir formation damage in the construction of complex-structure well,taking the inclined well section as the research object,the coordinate transformation method and conformal transformation method are given according to the flow characteristics of reservoir near wellbore in anisotropic reservoir.Then the local skin factor in orthogonal plane of wellbore is deduced.Considering the un-even distribution of local skin factor along the wellbore,the oscillation decreasing model and empirical equation model of damage zone radius distribution along the wellbore direction are established and then the total skin factor model of the whole well is superimposed to realize the reservoir damage evaluation of complex-structure wells.Combining the skin factor model with the production model,the production of complex-structure wells can be predicted more accurately.The two field application cases show that the accuracy of the model can be more than 90%,which can also fully reflect the invasion characteristics of drilling and completion fluid in any well section of complex-structure wells in anisotropic reservoir,so as to further provide guidance for the scientific establish-ment of reservoir production system.
