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从脾胃气化探讨难治免疫性血小板减少症证治 被引量:8
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作者 曾英坚 彭国蕊 +6 位作者 周露 刘凡 吴欣平 张大玲 欧阳丹 梁桢尧 张小萍 《中国中医急症》 2020年第12期2141-2143,共3页
难治免疫性血小板减少症常引起颅脑出血、内脏出血等急危重症,目前免疫抑制、促血小板生成等药物疗效有限。笔者将中医脾胃气化理论应用于难治免疫性血小板减少症的治疗中,取得了疗效的显著提高。
关键词 难治 免疫性血小板减少症 脾胃气化 证治浅析
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骨髓增生异常综合征患者应用青黄散临床疗效及对QOL评分的影响 被引量:2
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作者 曾英坚 彭国蕊 +3 位作者 姜建泽 刘凡 吴欣平 吴敏 《中国医学创新》 CAS 2019年第31期87-90,共4页
目的:探讨骨髓增生异常综合征患者应用青黄散临床疗效及对生活质量(QOL)评分的影响。方法:选取2016年1月-2018年1月本院收治的52例骨髓增生异常综合征患者,按随机数字表法分为对照组与研究组,各26例。对照组进行常规治疗,研究组进行青... 目的:探讨骨髓增生异常综合征患者应用青黄散临床疗效及对生活质量(QOL)评分的影响。方法:选取2016年1月-2018年1月本院收治的52例骨髓增生异常综合征患者,按随机数字表法分为对照组与研究组,各26例。对照组进行常规治疗,研究组进行青黄散治疗。比较两组治疗效果、外周血象、免疫功能及QOL评分。结果:研究组治疗总有效率高于对照组(χ^2=5.421,P<0.05);治疗前,两组血小板、血红蛋白与骨髓原始细胞百分比比较,差异均无统计学意义(P>0.05)。治疗后,研究组血小板、血红蛋白均高于对照组(P<0.05)。治疗后,两组骨髓原始细胞百分比比较,差异无统计学意义(P>0.05)。治疗后,研究组免疫功能各相关指标均优于对照组(P<0.05);研究组各项QOL评分均高于对照组(P<0.05)。结论:对骨髓增生异常综合征患者进行青黄散治疗,可有效改善临床症状,改善免疫功能和外血象,有利于病情恢复,提高生活质量,具有非常高的临床应用价值,应进一步推广和应用。 展开更多
关键词 骨髓增生异常综合征 青黄散 QOL 评分 不良反应
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白芍总苷胶囊联合强的松治疗原发免疫性血小板减少症临床观察 被引量:5
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作者 操儒森 曾英坚 +2 位作者 樊启辉 刘凡 吴滢 《光明中医》 2020年第22期3621-3623,共3页
目的观察白芍总苷胶囊联合强的松治疗成人慢性原发免疫性血小板减少症的临床疗效。方法将40例成人原发免疫性血小板减少症随机分为治疗组20例及对照组20例,治疗组以白芍总苷胶囊加强的松治疗,对照组仅以强的松治疗,观察血小板计数、巨... 目的观察白芍总苷胶囊联合强的松治疗成人慢性原发免疫性血小板减少症的临床疗效。方法将40例成人原发免疫性血小板减少症随机分为治疗组20例及对照组20例,治疗组以白芍总苷胶囊加强的松治疗,对照组仅以强的松治疗,观察血小板计数、巨核细胞、CD4+、CD8+T细胞计数变化情况。结果治疗组在提升血小板、减少巨核细胞数、改善T细胞亚群方面显著优于对照组(P<0.05)。结论白芍总苷胶囊治疗成人慢性原发免疫性血小板减少症有明显的效果,值得进一步研究。 展开更多
关键词 白芍总苷胶囊 原发免疫性血小板减少症 中医药疗法
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Visual analysis of research hotspots and trends in the treatment of immune thrombocytopenia with traditional Chinese medicine 被引量:2
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作者 GAO Yao WU Zhenhui +5 位作者 WU Min Abid Naeem LI Weizhizi ZHANG Daling LIU Fan zeng yingjian 《Digital Chinese Medicine》 2022年第3期326-339,共14页
Objective Through bibliometrics and visual analysis of the related studies on traditional Chinese medicine(TCM)treatment of immune thrombocytopenia(ITP),this study aims to sort out the overall research progress,hotspo... Objective Through bibliometrics and visual analysis of the related studies on traditional Chinese medicine(TCM)treatment of immune thrombocytopenia(ITP),this study aims to sort out the overall research progress,hotspots,and trends in this field,and provide reference for further research in ITP.Methods The articles on ITP treated by TCM were retrieved from China National Knowledge Infrastructure(CNKI),Wanfang Database,China Science and Technology Journal Database(VIP),Web of Science Core Collection(WOSCC),and PubMed.The retrieval time was from the establishment of the databases to July 31,2022.VOSviewer,CiteSpace,Carrot2,and Note-Express were used for data analysis of the articles in terms of their quantities,types,and journals,and for visualization of research hotspots,authors,institutions,and keywords.Results 1493 Chinese articles and 40 English articles were included.The articles in Chinese mainly focus on clinical trial research and clinical experience summary,while the English articles mainly focus on clinical trial research and animal research.The Chinese articles were published in 317 Chinese journals,while English articles were published in 29 English journals.Research hotspots include the clinical syndrome differentiation of ITP,the therapeutic effect of TCM compounds on ITP,and the mechanism of ITP treatment.Keyword analysis shows that there are many research achievements in integrated traditional Chinese and western medicine treatment,clinical research,famous doctors’experience,TCM treatment,cellular immunity,and humoral immunity.The authors with the most articles in Chinese and English are Professor CHEN Xinyi and Professor MA Rou,respectively,and the research institutions with the most articles are Dongzhimen Hospital of Beijing University of Chinese Medicine and Xiyuan Hospital of China Academy of Chinese Medical Sciences.Chinese herbs often used to treat ITP clinically include Xianhecao(Agrimoniae Herba),Nvzhenzi(Ligustri Lucidi Fructus),Mohanlian(Ecliptae Herba),Zhongjiefeng(Sarcandrae Herba),etc.,and the prescription usually used to treat ITP include Guipi Decoction(归脾汤),Xijiao Dihuang Decoction(犀角地黄汤),Bazhen Decoction(八珍汤),Erzhi Pill(二至丸),and Xiaochaihu De-coction(小柴胡汤).The main development trends toward retrospective study,TCM treatment mechanism,and data mining. 展开更多
关键词 Immune thrombocytopenia Traditional Chinese medicine(TCM) BIBLIOMETRICS Visual analysis CiteSpace VOSviewer Carrot2 Research hotspot
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