Pertussis is an acute and highly contagious respiratory disease caused by Bordetella pertussis(B.pertussis),which occurs in people of all ages and is most dangerous for young children,especially infants.The introducti...Pertussis is an acute and highly contagious respiratory disease caused by Bordetella pertussis(B.pertussis),which occurs in people of all ages and is most dangerous for young children,especially infants.The introduction of whole-cell pertussis vaccines(wPVs)in the 1950s dramatically reduced the incidence of pertussis worldwide[1].However,over the past two decades,many studies have reported the resurgence of pertussis in different countries[2].Epidemiological surveillance in Hubei Province over the last 3 years revealed a clear increasing trend in the incidence of pertussis during the coronavirus disease 2019(COVID-19)epidemic.展开更多
Neisseria meningitidis(N.meningtitidis)is a gram negative diplococcus.Neisseria meningitidis(meningococcus)was first identified in the cerebrospinal fluid of a patient with meningitis in 1887 by Weichselbaum,and the e...Neisseria meningitidis(N.meningtitidis)is a gram negative diplococcus.Neisseria meningitidis(meningococcus)was first identified in the cerebrospinal fluid of a patient with meningitis in 1887 by Weichselbaum,and the epidemic was traced back to 1805[1].The serogroups A,B,C,W,X,and Y were the most frequent causes of meningococcal diseased[1].N.meningitidis usually colonizes the human nasopharynx[2].The common clinical manifestations of invasive N.meningitidis infection are meningococcemia and acute meningitis[2].Some patients with meningococcal disease may present with pneumonia,arthritis,pericarditis,conjunctivitis,epiglottitis,sinusitis,otitis,urethritis,and proctitis[2].However,patients rarely present with acute peritonitis initially.展开更多
基金supported by Hubei Province Key R&D Program Project,grant number 2020BCA090,2021BCA148,2022BCE010The Medical Scientific Research Foundation of Hubei Province,China,grant number No.JX6B23+1 种基金the Natural Science Foundation of Hubei Province,grant number 2018CFB630Open Foundation of the Hubei Key Laboratory of Edible Wild Plants Conservation and Utilization[EWPL202301].
文摘Pertussis is an acute and highly contagious respiratory disease caused by Bordetella pertussis(B.pertussis),which occurs in people of all ages and is most dangerous for young children,especially infants.The introduction of whole-cell pertussis vaccines(wPVs)in the 1950s dramatically reduced the incidence of pertussis worldwide[1].However,over the past two decades,many studies have reported the resurgence of pertussis in different countries[2].Epidemiological surveillance in Hubei Province over the last 3 years revealed a clear increasing trend in the incidence of pertussis during the coronavirus disease 2019(COVID-19)epidemic.
基金supported by the National Natural Science Foundation of China[32000066]the Young and Middleaged Talents Project of Hubei Provincial Department of Education[Q20202505]+2 种基金Key Projects of Chibi Science and Technology Bureau in Hubei Province,China[2019SF001]Innovation Team Project of Hubei Normal University[T201907]and the Open Foundation of the Hubei Key Laboratory of Edible Wild Plants Conservation and Utilization[EWPL202008]at Hubei Normal University.
文摘Neisseria meningitidis(N.meningtitidis)is a gram negative diplococcus.Neisseria meningitidis(meningococcus)was first identified in the cerebrospinal fluid of a patient with meningitis in 1887 by Weichselbaum,and the epidemic was traced back to 1805[1].The serogroups A,B,C,W,X,and Y were the most frequent causes of meningococcal diseased[1].N.meningitidis usually colonizes the human nasopharynx[2].The common clinical manifestations of invasive N.meningitidis infection are meningococcemia and acute meningitis[2].Some patients with meningococcal disease may present with pneumonia,arthritis,pericarditis,conjunctivitis,epiglottitis,sinusitis,otitis,urethritis,and proctitis[2].However,patients rarely present with acute peritonitis initially.
