The spatiotemporal regulation of threedimensional(3D)genome dynamics has been implicated in various genome functions including gene transcription,DNA recombination,DNA replication,and DNA repair(Bickmore,2013).
基金the National Natural Science Foundation of China(81572795 and 81773304)the‘Hundred,Thousand and Ten Thousand Talent Project’by Beijing Municipal Government(2017A02)the National Natural Science Foundation of China(31701135).We thank Beijing Municipal Government and the Ministry of Science and Technology of China for funds allocated to NIBS.D.H.and Y.Z.conceived the study.D.H.,X.M.t G.L.J.D.,Y.H.y Q.H.f J.X.f and X.S.performed experiments and analyzed data.Y.Z.analyzed data and wrote the manuscript with support from all authors.
文摘The spatiotemporal regulation of threedimensional(3D)genome dynamics has been implicated in various genome functions including gene transcription,DNA recombination,DNA replication,and DNA repair(Bickmore,2013).
