The prevalence and persistence of antibiotics in soils has become an emerging environmental issue and an increasing threat to soil security and global public health. The problem is more severe in areas undergoing rapi...The prevalence and persistence of antibiotics in soils has become an emerging environmental issue and an increasing threat to soil security and global public health. The problem is more severe in areas undergoing rapid urbanization; however, the ecological risks of antibiotics,seasonal variability, and associated soil microbial responses in peri-urban soils have not been well-explored. The seasonal soil sampling campaigns were conducted in a typical peri-urban watershed in eastern China to investigate distribution of antibiotics. The results demonstrated higher mean concentrations of most antibiotic compounds in winter than in summer in periurban soils. The seasonal variations of norfloxacin, enrofloxacin, and ciprofloxacin were more significant than those of other antibiotics, due to their higher migration ability and bioavailability.An ecological risk assessment demonstrated that chlortetracycline, ciprofloxacin, doxycycline,and ofloxacin can pose high risks to soil microorganisms. Furthermore, the coexistence of multiple antibiotics obviously poses higher risks than individual compounds. A redundancy analysis demonstrated that tetracyclines mainly showed negative correlations with Firmicutes and Chloroflexi, and quinolones showed obviously negative correlations with Acidobacteria,Gemmatimonadetes, and Nitrospirae, suggesting potential inhibition from antibiotics on biological activities or biodegradation processes. However, the persistence of antibiotics in soil results in a significant decrease in bacterial diversity and a change in dominant species.Our results provide an overview of the seasonal variability of antibiotics and the associated effects on bacterial communities in peri-urban soils. The results can provide scientific guidance on decreasing soil contamination with antibiotics to enhance soil security in similar areas.展开更多
The International Symposium on Sub-optimal Health Status was held in the beautiful“deer city”of Baotou,Inner Mongolia,China,from September 12 to September 13,2015.The symposium was hosted by Global Suboptimal Health...The International Symposium on Sub-optimal Health Status was held in the beautiful“deer city”of Baotou,Inner Mongolia,China,from September 12 to September 13,2015.The symposium was hosted by Global Suboptimal Health Association and Capital Medical University and was cosponsored by the Beijing Municipal Key Laboratory of Clinical Epidemiology,Baotou Central Hospital,and Ruike-Donghua Translational Medicine Center,Beijing.展开更多
基金supported by the National Natural Science Foundation of China(Nos.41571130064 and 41701018)the Youth Innovation Promotion Association,Chinese Academy of Sciences(No.2018057)
文摘The prevalence and persistence of antibiotics in soils has become an emerging environmental issue and an increasing threat to soil security and global public health. The problem is more severe in areas undergoing rapid urbanization; however, the ecological risks of antibiotics,seasonal variability, and associated soil microbial responses in peri-urban soils have not been well-explored. The seasonal soil sampling campaigns were conducted in a typical peri-urban watershed in eastern China to investigate distribution of antibiotics. The results demonstrated higher mean concentrations of most antibiotic compounds in winter than in summer in periurban soils. The seasonal variations of norfloxacin, enrofloxacin, and ciprofloxacin were more significant than those of other antibiotics, due to their higher migration ability and bioavailability.An ecological risk assessment demonstrated that chlortetracycline, ciprofloxacin, doxycycline,and ofloxacin can pose high risks to soil microorganisms. Furthermore, the coexistence of multiple antibiotics obviously poses higher risks than individual compounds. A redundancy analysis demonstrated that tetracyclines mainly showed negative correlations with Firmicutes and Chloroflexi, and quinolones showed obviously negative correlations with Acidobacteria,Gemmatimonadetes, and Nitrospirae, suggesting potential inhibition from antibiotics on biological activities or biodegradation processes. However, the persistence of antibiotics in soil results in a significant decrease in bacterial diversity and a change in dominant species.Our results provide an overview of the seasonal variability of antibiotics and the associated effects on bacterial communities in peri-urban soils. The results can provide scientific guidance on decreasing soil contamination with antibiotics to enhance soil security in similar areas.
基金The SHS study was supported by the grants from the National Projects of the Ministry of Science and Technology of China(2006AA02Z434 and 2012BAI37B03)the National Natural Sciences Foundation of China(30800949 and 1747853)+3 种基金the Australian National Health and Medical Research Council(APP1112767)Edith Cowan University Industry Collaboration Scheme 2013(G1001368)Edith Cowan University Strategic Research Fund(2015-2016)COACS was run by Rec Data Medical Science Foundation and Recovery Medical Science Foundation.
文摘The International Symposium on Sub-optimal Health Status was held in the beautiful“deer city”of Baotou,Inner Mongolia,China,from September 12 to September 13,2015.The symposium was hosted by Global Suboptimal Health Association and Capital Medical University and was cosponsored by the Beijing Municipal Key Laboratory of Clinical Epidemiology,Baotou Central Hospital,and Ruike-Donghua Translational Medicine Center,Beijing.
